Andrew Bissette
andrewbissette.bsky.social
Andrew Bissette
@andrewbissette.bsky.social
Recovering prebiotic chemist. Editor in Chief at Cell Reports Physical Science @cp-cellrepphyssci.bsky.social. Personal account, views not my employer's, etc.
Pinned
STEM editorial & publishing starter pack: go.bsky.app/7aTGjKw
Reposted by Andrew Bissette
They’ll have left a trail to follow
November 27, 2025 at 10:11 PM
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Come for the dough pun, stay for the hidden chemistry pun (He = helium, which is the gas in the balloon and what causes it to float (rise))
November 27, 2025 at 4:20 PM
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Handing back student work that’s been written by ChatGPT with a 0 followed by the comment “This essay will never stand in authentic wonder before the Beauty of God’s creation.”
Pope Leo XIV told students not to use artificial intelligence for homework, saying that AI ‘won’t stand in authentic wonder before the beauty of God’s creation.’
Even God Is Worried About ChatGPT
Pope Leo XIV told students not to use artificial intelligence for homework, saying that AI ‘won’t stand in authentic wonder before the beauty of God’s creation.’
www.vulture.com
November 26, 2025 at 3:35 PM
Things I find inconsiderate #567: when conference catering provide<10 sandwiches for the vegan attendees, and everyone else treats them as just another interesting option to have alongside the meat based selection.
November 26, 2025 at 1:16 PM
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Not that you asked, but here's a thread of intriguing 100% FAKE chemistry facts to amuse/bore your friends and family.

Great for gatherings when you need to change the subject!

(Feel free to add your own!)

#chemchat
Not that you asked, but here's a thread of intriguing (real!) food facts to amuse/bore your friends and family.

Great for gatherings when you need to change the subject!
November 25, 2025 at 8:31 PM
Reposted by Andrew Bissette
It is ridiculous that startup founders and only startup founders will say chemical synthesis is the bottleneck. It was ridiculous when Revolution Medicines said it in ~2010, it's ridiculous now.
Onepot.AI has launched with $13 million in funding to use artificial intelligence and robotics to automate one of the most time-consuming steps in drug development: chemical synthesis. cen.acs.org/business/sta... #chemsky 🧪
Molecule-maker Onepot.AI launches with $13 million
With an AI engine named Phil and a robotic platform, the start-up cuts down on synthesis turnaround
cen.acs.org
November 25, 2025 at 3:23 PM
Reposted by Andrew Bissette
I cannot imagine what could possibly go wrong in trying to court-martial an astronaut and pilot decorated multiple times for valor and exceptional service, who is also a sitting senator, for correctly making the point that service members are obliged not to follow unlawful orders
Hegseth is now threatening to recall Sen. Mark Kelly to active duty in order to court martial him.
November 24, 2025 at 6:45 PM
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Ask not how many tabs you can have open,
But ask how many tabs you can have open per window
November 24, 2025 at 3:45 PM
Really enjoyed this Q&A @cp-patterns.bsky.social with five AI researchers, asking whether AI is overhyped. www.cell.com/patterns/ful...
Is AI overhyped?
In this People of Data, we asked five researchers, including three members of the journal’s advisory board, whether they feel AI technologies are currently overhyped. Their responses reveal both optim...
www.cell.com
November 24, 2025 at 1:38 PM
Reposted by Andrew Bissette
I tried an even harder example on Gemini Pro image generation and this is quite scary/amazing. I asked for a microscopy image of around 20 HeLa cells, GFP tagged 20% nuclear, 10% membrane, +1 nuclear staining, + overlap. Image below and prompt in the following post.
November 21, 2025 at 5:32 PM
Honestly LLMs have really improved my writing. Not through using them, mind. But trying to avoid sounding like them has really cured me of some bad habits.
November 22, 2025 at 3:09 PM
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I feel like an absolute Cassandra. I definitely remember having a conversation in supervision 2 and a half years ago about how they'll come for Gillick competence, and later it'll be contraceptives and a persons right to abortion.
Kathleen Stock has written an article against "abortion permissiveness". She claims abortion requires "justification" saying the state should limit "unacceptable decision-making" by women about their own bodies.

This is who anti-trans activists proclaim as the feminist thought leaders of our time.
November 21, 2025 at 3:41 PM
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any suggestions for a equivalent reagent for Na/Hg?
November 21, 2025 at 11:48 AM
Reposted by Andrew Bissette
How do we make sense of scientific literature that is growing explosively to the point where no-one could read all the relevant papers, and is contaminated with fraudulent and LLM-generated papers? I think that science isn't currently equipped to deal with this, and we need to. #science #metascience
November 20, 2025 at 5:01 PM
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every company in 2025
November 12, 2025 at 5:59 PM
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November 18, 2025 at 2:28 PM
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A thread of some cartoons rejected by The New Yorker:
November 20, 2025 at 10:56 PM
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These same folks extremely committed to fighting antisemitism in universities
Exclusive: The U.S. Coast Guard will no longer classify the swastika, nooses and the Confederate flag as hate symbols.

The military service drafted a new policy that classifies them as “potentially divisive.”
U.S. Coast Guard will no longer classify swastikas, nooses as hate symbols
The military service, which falls under the Department of Homeland Security, has drafted a new policy that classifies such items “potentially divisive.”
www.washingtonpost.com
November 20, 2025 at 10:34 PM
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The Punctuation Collection™️
November 20, 2025 at 2:37 PM
Reposted by Andrew Bissette
Analytical chemistry has become extremely automated in the last 25 years, and yet shit continues to break in new and befuddling ways that AI can’t possibly parse. The “datasets” for it to learn instrument repairs from exist in the minds of experts and are significantly vibes-based.
A fair question is how much of a day's work could be outsourced to a machine? As I've become proficient with AI tools, I find that much of what takes me time (but not deep cognitive effort) can be automated. PhDs are hired, at least in part, for their thinking skills. Not all jobs require them.
November 20, 2025 at 1:16 AM
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#chemchat
i need your best inorganic memes. Go
November 18, 2025 at 2:14 PM
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Not just because I'm writing a book on #BattlestarGalactica, but damn I wish this show was streaming right now (it's not! this is Not Good). Partly bec it's MORE relevant than ever, partly bec it fucking rules, mainly bec Laura Roslin shouting "I'M COMING FOR ALL OF YOU" is now my entire personality
November 18, 2025 at 3:15 AM
Reposted by Andrew Bissette
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
November 18, 2025 at 10:18 AM