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Reposted by Alex Shackman

David Cooper @davidbcooper.bsky.social · 14h

Rosie the Ribbiter

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Alex Shackman @ajshackman.bsky.social · 11h

Clay wins. The last iteration of his lab website was cool. This even cooler.

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Ted McCormick @tedmccormick.bsky.social · 12h

Shared courtesy of my Penn History colleague, Ben Nathans

Image: A variation on Benjamin Franklin’s “Join, or Die” engraving, originally published in the Pennsylvania Gazette in 1754. Each segment of the snake has the name of a university sent Trump’s “compact”: Texas, AZ, Vanderbilt, USC, Dartmouth, UVA, Brown, Penn, MIT.

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Dana Houle @danahoule.bsky.social · 1d

Chicagoland is a friendly, safe, vibrant, & fun place. I’m very happy my kids have grown up in the Rogers Park neighborhood of the city, & in Evanston. They’re both wonderful places.

But ICE is attacking us. People are doing everything possible to protect their neighbors. But it’s hard.

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Prof Sam Illingworth @samillingworth.com · 2d

💉 2024–25 Covid-19 vaccine effectiveness

In U.S. veterans, the updated vaccine reduced 6-month risks of Covid-related ED visits (-29%), hospitalisations (-39%), and deaths (-64%) vs flu-only group.

🔗 doi.org/10.1056/NEJMoa2510226

#SciComm #COVID19 #Vaccines 🧪

Association of 2024–2025 Covid-19 Vaccine with Covid-19 Outcomes in U.S. Veterans | NEJM

Amid the declining clinical severity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and diminishing public uptake of annual coronavirus disease 2019 (Covid-19) vaccines, ...

doi.org

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Alex Shackman @ajshackman.bsky.social · 1d

9/n. Another puzzle piece: #BLA NotJust #B$T Differential Recruitment of Competing Valence-Related Amygdala Networks during Anxiety www.cell.com/neuron/pdfEx...

www.cell.com

Alex Shackman @ajshackman.bsky.social · 1d

Great discussion: jingle/jangle, precision of nomenclature, what is arousal, dissociable flavors of arousal, weak coherence of emo response channels, boomerang-shaped norm IAPS SAM ratings, limitations of signatures & Ianetti/Apkarian critique, etc.

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Alex Shackman @ajshackman.bsky.social · 1d

psycnet.apa.org/doiLanding?d... How attention and working memory married and divorced, with JEP: HPP as the witness.
Olivers, Roelfsema, Soto & Woodman (2025).

APA PsycNet

psycnet.apa.org

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Alex Shackman @ajshackman.bsky.social · 2d

Today's target article

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Alex Shackman @ajshackman.bsky.social · 3d

Portland FTW

Adam Serwer @adamserwer.bsky.social · 3d

www.wweek.com/culture/2025...

Can you put into words what that purpose is? You and the frog have really become icons of this protest.

There’s been a nice overall whimsy that has shown up. The frog is amazing. We had a bunch of other inflatable people here last night, too. I saw people playing Twister the other day.

What they rely on is fear. So by coming out in an absurdist manner, it speaks to them, to some extent, that we’re actually not that afraid.

It also dismantles their narrative a little bit. When they try to describe this situation as “war-torn,” it becomes much harder to take them seriously when they have to post a video saying [U.S. Secretary of Homeland Security] Kristi Noem is up on the balcony staring over the Antifa Army and it’s, like, eight journalists and five protesters and one of them is in a chicken suit.

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Alex Shackman @ajshackman.bsky.social · 4d

www.sciencedirect.com/science/arti...

Sensory reformatting for a working visual memory

A core function of visual working memory (WM) is to sustain mental representations of recent visual inputs, thereby bridging moments of experience. Th…

www.sciencedirect.com

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Bethany Albertson @albertsonb2.bsky.social · 5d

My all time favorite Dolly Parton quote - if you feel like sharing yours, it's been a day...

“I'm not offended by all the dumb blonde jokes because I know I'm not dumb—and I'm not blonde either.”

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Alex Shackman @ajshackman.bsky.social · 4d

psychiatryonline.org/doi/10.1176/...

Reduced Threat-Related Neural Efficiency: A Possible Biomarker for Pediatric Anxiety Disorders | American Journal of Psychiatry

Objective: Pediatric anxiety disorders are common and predict adult psychopathology, yet current treatments, such as cognitive-behavioral therapy (CBT), produce lasting remission in less than 50% of a...

psychiatryonline.org

Alex Shackman @ajshackman.bsky.social · 4d

Mazel tov, Zane! bsos.umd.edu/featured-con...

Weizhen Xie Receives 2025 Young Investigators Award

bsos.umd.edu

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Miri Forbes @miriforbes.bsky.social · 5d

We’ve just published another video on HiTOP that tries to flesh out a bit more how the framework can be helpful in research: youtu.be/q0jOi_Nl1yo

We hope it’s useful, and are keen to hear any feedback

Thanks again so much to @tashtc.bsky.social for all of her hard work creating this video series ✨

Using HiTOP in Research

YouTube video by HiTOP

youtu.be

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Alex Shackman @ajshackman.bsky.social · 5d

Worth re-reading. #Nibble

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Alex Shackman @ajshackman.bsky.social · 5d

8/n. Yet, in contrast to work in humans and animals outside the scanner, imagers have yet to tackle this fundamental question. Why? Generally, the ITI contributes to the implicit baseline in std 1st-level fMRI GLM's, and std (uncalibrated) fMRI is insensitive to slow signals (1/f noise), h/t RikH

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Alex Shackman @ajshackman.bsky.social · 5d

7/n. it's effectively a (complex) cue indicating p>0 of future threat encounters (p=1 in mouse & DeGeneres; p=0.5 in Lissek; p>0 in NHP). It's sensitive to BST/BNST function & loss-of-function pubmed.ncbi.nlm.nih.gov/19692610/

The bed nucleus of the stria terminalis mediates inter-individual variations in anxiety and fear - PubMed

While learning to fear stimuli that predict danger promotes survival, the inability to inhibit fear to inappropriate cues leads to a pernicious cycle of avoidance behaviors. Previous studies have reve...

pubmed.ncbi.nlm.nih.gov

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Alex Shackman @ajshackman.bsky.social · 5d

6/n. There is something important and interesting about this persistent state of elevated defensive responding, likely reflecting the fact that the ITI is not just 'dead-time' between cues,

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Alex Shackman @ajshackman.bsky.social · 5d

5/n. And Lissek's patients, during the Pavlovian threat conditioning ITI (outlier dots on the left-most portion of the patient panels)

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Alex Shackman @ajshackman.bsky.social · 5d

4/n. Or dispositionally anxious monkeys in the minutes following a threat encounter ... shackmanlab.org/wp-content/u...

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Alex Shackman @ajshackman.bsky.social · 5d

3/n. Or this woman living w/ with social anxiety at work, between moments of performance/scrutiny www.youtube.com/watch?v=O5nP...

Social Anxiety Disorder: Afraid of People (Social Phobia Documentary)

YouTube video by REALWOMEN/REALSTORIES

www.youtube.com

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Alex Shackman @ajshackman.bsky.social · 5d

2/n. My mind goes to videos of people traversing haunted houses (or watching a horror movie), in the moments between jump scares (YT search for Ellen DeGeneres & Andy & Haunted House). e.g. www.youtube.com/watch?v=ZXZ6...

Andy and Amy's Haunted House

YouTube video by TheEllenShow

www.youtube.com

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Alex Shackman @ajshackman.bsky.social · 5d

1/n. #FearAndAnxiety #Mice. I'm currently obsessed with Fig S1 from Wang...& Tejeda '24. Check out the persistent freezing in the CS+ ITI's during acquisition. Does anyone have sharable video of something similar in rats or mice?

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altNOAA 🇺🇸 @altnoaa.bsky.social · 5d

Antifa Gang Tattoo Identification
Radical symbols may include “AA” (may include numbers like 82nd), a screaming eagle (may include numbers like 101st), or cryptic Latin like “De Oppresso Liber” (translation: definitely plotting). Learn to ID Antifa™!

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