Alex Shackman
ajshackman.bsky.social
Alex Shackman
@ajshackman.bsky.social
Laboratory for Affective & Translational Neuroscience, University of Maryland | shackmanlab.org | affective neuroscience | "pessimism of the intellect, optimism of the will.”
Reposted by Alex Shackman
Some additional updates to deadlines have been released for grant submissions that fell during the shutdown

grants.nih.gov/grants/guide...
NOT-OD-26-012: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated Guidance on Reopening of NIH Extramural Activities Following the October 1, 2025 - Lapse in Appropriations NOT-...
grants.nih.gov
November 25, 2025 at 3:16 AM
Reposted by Alex Shackman
Not only that, but there is a Nobel prize (or 2 or 3 or 4) behind most of those fundamental discoveries.
Every machine in a Hospital that diagnoses your body without cutting you open is based on a principle of Physics, discovered by a Physicist who had no interest in Medicine.

If you think the world doesn’t need Basic Science, or that somehow Science has failed you, think again.

#sciencematters
November 25, 2025 at 11:38 AM
Reposted by Alex Shackman
#PenNLINC is recruiting a clinical coordinator / lab manager!!! Looking for someone who is good with both people + code, wants to learn to acquire + analyze imaging data. Alumni in this role have written 1st author papers + gone to top grad programs.

Website: www.pennlinc.io

Job: bit.ly/4ojvCir
neuroimaging | Satterthwaite Lab | UPenn
www.satterthwaitelab.com Homepage for Satterthwaite lab neuroimaging | neurodevelopment | adolescence | psychiatry | machine learning | network science
www.pennlinc.io
November 24, 2025 at 9:59 PM
Adding to my classroom slides Wenzel...(2025). Unraveling the link between neuroticism and well-being in daily life: The role of event occurrence, event appraisals, affective reactivity, and affective recovery. Jpsp. doi.org/10.1037/pspp...
APA PsycNet
doi.org
November 25, 2025 at 11:54 AM
Reposted by Alex Shackman
PS is excited to announce the launch of "Individual Differences in Cognition” (IDIC), an open-access journal on research in cognitive psychology, science, and neuroscience. Co-Editors-in-Chief are Andrew R.A. Conway & Michael J. Kane. Manuscripts accepted this spring. More information coming soon!
November 22, 2025 at 10:09 PM
Reposted by Alex Shackman
Interacting processes operating on vastly different timescales (from milliseconds to millennia) shape emergence & properties of human language(s). Roles of biology & culture, & the complex interplay between them, can be empirically investigated in humans, nonhuman animals & computational models. 8/n
November 23, 2025 at 11:54 AM
Reposted by Alex Shackman
What’s the lore behind choosing your career path ?
November 11, 2025 at 4:41 PM
Harrison, T. J., Lawhead, C., Calentino, A. E., Grieshaber, A., Katz, B. A., Silver, J., Olino, T. M., & Klein, D. N. (2025). Intergenerational transmission of depression: Testing a comprehensive set of putative mediators. JPCS, 134(7), 733–745. doi.org/10.1037/abn0...
APA PsycNet
doi.org
November 22, 2025 at 5:50 PM
Reposted by Alex Shackman
I wrote a little bit about the "missing heritability" question and several recent studies that have brought it to a close. A short 🧵
The missing heritability question is now (mostly) answered
Not with a bang but with a whimper
theinfinitesimal.substack.com
November 21, 2025 at 10:34 PM
Reposted by Alex Shackman
fascinating idea.
November 21, 2025 at 9:50 PM
I found myself using these multiple times in Zoom meetings this week. Very handy for one-on-one mentoring of ugrads/grads, teaching, and thinking....https://rpsychologist.com/viz . Big thanks to @rpsychologist.com !
November 21, 2025 at 6:53 PM
Reposted by Alex Shackman
And the next step? Full voxel-level modeling.

Recent numerical advances cracked the scalability barrier. Voxel-level hierarchical modeling is now feasible, revealing just how punishing traditional multiple-comparison adjustments really are.
arxiv.org/abs/2511.12825
SIMBA: Scalable Image Modeling using a Bayesian Approach, A Consistent Framework for Including Spatial Dependencies in fMRI Studies
Bayesian spatial modeling provides a flexible framework for whole-brain fMRI analysis by explicitly incorporating spatial dependencies, overcoming the limitations of traditional massive univariate app...
arxiv.org
November 18, 2025 at 10:13 PM
Reposted by Alex Shackman
6 Suggestions for DSM-6

Making the next DSM look less like a house of mirrors

www.psychiatrymargins.com/p/6-suggesti...
6 Suggestions for DSM-6
Making the next DSM look less like a house of mirrors
www.psychiatrymargins.com
November 20, 2025 at 11:55 PM
Reposted by Alex Shackman
As the Neuroscience 2025 meeting comes to a close, it's time for us to think about the future. Do you want to help us shape neuroscience research and future @sfn.org meetings? Consider nominating yourself or colleagues: www.sfn.org/about/volunt...
Call for Nominations
www.sfn.org
November 21, 2025 at 12:16 AM