Lightnews — Scholar-powered news

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Jeffrey J. Gray @jeffreyjgray.bsky.social · 7d

Excited to share our new preprint “Unified Sampling and Ranking for Protein Docking with DFMDock” by PhD candidate Lee-Shin Chu and Post-Doc Sudeep Sarma! We designed a diffusion docking model that samples rigid-body conformations by predicting forces and ranks poses using predicted energies.

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Krystal Tsosie @kstsosie.bsky.social · 8h

Out today via @natgenet.nature.com, the first federally funded #Tribal #data repository, a revolutionary approach to data management and applied/operationalization of IDSov @d4itdr.bsky.social. Also, if you are at #ASHG25, come see us this morning in 205ABC
www.nature.com/articles/s41...

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aslynn's tremendous 'tism horror show 👻 🎃 @audhd-psychnp.com · 1d

The SPACE acronym comprises 5 needs of autistic people: Sensory needs, Predictability, Acceptance, Communication & Empathy.

In 3 essential domains: Physical space, Processing space and Emotional space.

Here we will consider the relevance of these domains in the educational context:

Dr Aoife Munroe @aoifemunroe.bsky.social · Aug 25

📣Publication Announcement!

Our article 'Autistic SPACE for Inclusive Education' has been published open access with Neurodiversity Journal 📑

doi.org/10.1177/2754...

Autistic SPACE for Inclusive Education - Elaine McGoldrick, Aoife Munroe, Rachel Ferguson, Carina Byrne, Mary Doherty, 2025

The continuing policy commitment to Inclusive Education internationally requires the prioritisation of the creation of inclusive schools in practice. Research w...

doi.org

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Kate Clancy @kateclancy.bsky.social · 1d

I am being asked to tell my department which pieces of lab equipment should be supported with backup power because they expect rolling blackouts and brownouts in 2026 due to increased energy demands from AI. In case you're wondering how my day is going.

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Alt CDC (they/them) @altcdc.altgov.info · 1d

📣Protesting is important. It is a visible reminder that we are not alone and that we are not powerless. It sends a message to those weak men in DC: that we will not give up our freedoms without a fight 🇺🇸

See you on Saturday. Bring friends 💪

#NoKings 🚫👑

www.nokings.org

No Kings

As the president escalates his authoritarian power grab, the NO KINGS non-violent movement continues to rise stronger. We are united once again to remind the world: America has No Kings and the power ...

www.nokings.org

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Katie Slivensky @kslivensky.bsky.social · 1d

4yo, playing with plastic dinos, humming a mournful tune:

"This is the part where the dinosaurs die."

*hides dinos; pulls out a stuffed hippo and a lion flashlight*

"And this is the part where new creatures come out."

*pulls out 3 Little People™ and a toy saw*

"Then humans come, with tools."

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Vikram Alva @vikramalva.bsky.social · 1d

Our Pyrodictium cannulae paper is out in its final form! Cannulae assemble into calcium-stabilized tubular filaments stable at 100 °C—a unique archaeal cell–cell connection. Led brilliantly by @mikesleutel.bsky.social & @vinceconticello.bsky.social.

www.nature.com/articles/s41467-025-64120-8

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Jennifer Molidor @jennifermolidor.bsky.social · 5d

Hanging onto every bit of good news

The river has come alive in the Klamath with wild Chinook salmon. The wider ecosystem is healing.

This most powerful story of Indigenous-led #rewilding after the largest dam removal in US history keeps getting better.

lostcoastoutpost.com/2025/oct/9/o...

One Year After Klamath Dam Removal, 'There's Just Fish Jumping All Over the Place': Scientists Describe Improvements to Water Quality and Wildlife

lostcoastoutpost.com

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Molly Knight @mollyknight.bsky.social · 3d

Whistling when ICE is about to kidnap someone for no reason is incredibly effective. They know what they are doing is wrong and will scatter in the wind when too many witnesses gather.

FORM A CROWD
STAY LOUD
PROTECT EACH OTHER
CODE I:
ICE NEARBY
BLOW QUICKLY IN A BROKEN RHYTHM:
PRE-PRE-PRE!
→ ALERTS THE COMMUNITY THAT ICE AGENTS ARE IN THE AREA.
ROGERS PARK WHISTLE PROTOCOLS
WHY A WHISTLE? ON THE STREETS
• A SIMPLE TOOL FOR FAST ALERTS.
• LOUD.
RECOGNIZABLE.
IMPOSSIBLE TO IGNORE.
• OUR VOICES ARE
STRONGER TOGETHER.
WHISTLES GUIDE
PEOPLE TO:
• FOLLOW ICE CARAVANS
• CATCH UP WITH THE CROWD
• ALERT NEIGHBORS
TO JOIN IN
NOISE = VISIBILITY.
CODE 2:
CODE RED
BLOW THREE LONG BLASTS:
PREEEE-PREEEE-PREEEE!
→ ICE IS DETAINING SOMEONE.
FORM A CROWD, STAY LOUD.
DON'T STAY SILENT. STAY NONVIOLENT.
WHY IT WORKS
• INSTANT ALERT
SYSTEM
• FASTER THAN SOCIAL MEDIA
• TURNS SILENCE INTO COMMUNITY
ACTION
ORIGINAL FLYER CREATED BY:
WHAT YOU CAN DO
• WEAR YOUR WHISTLE AROUND YOUR NECK
TEACH FAMILY
EIGHBORS TH
CODES
• USE IT WHEN ICE IS
SPOTTED
• PROTECT EACH OTHER, ALWAYS
TOGETHER, WE KEEP OUR COMMUNITY SAFE.
FORM A CROWD, STAY LOUD.
THIS FLYER DISTRIBUTED BY:
PROTECT RP
• @PROTECTRP_

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Yehlin Cho @yehlincho.bsky.social · 2d

Thrilled to announce our new preprint, “Protein Hunter: Exploiting Structure Hallucination within Diffusion for Protein Design,” in collaboration with @Griffin, @GBhardwaj8 and @sokrypton.org

🧬Code and notebooks will be released by the end of this week.
🎧Golden- Kpop Demon Hunters

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Chise @sailorrooscout.bsky.social · 3d

GOOD NEWS! Researchers have developed a cancer vaccine that has shown STUNNING results, PREVENTING up to 88% of MULTIPLE aggressive cancers by harnessing dual-pathway nanoparticles that train the immune system to recognize and destroy tumor cells. In some cases, it COMPLETELY prevented metastasis.

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Anne Carpenter @drannecarpenter.bsky.social · 5d

15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵

mitochondria from bipolar patients are closer to the nucleus in these images; control patients' are spread out further

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Scott Fabricant MD PhD @safabric.bsky.social · 3d

In honour of spooky month, share a 4 word horror story that only someone in your profession would understand.

"Cefiderocol-resistant Pseudomonas osteomyelitis" 👻👻

Darren Irwin (he / him) @darrenirwin.bsky.social · 3d

In honour of spooky month, share a 4 word horror story that only someone in your profession would understand.

"Developed new species concept"

Marjorie James Keenan @unenthusiast.com · 3d

In honour of spooky month, share a 4 word horror story that only someone in your profession would understand.

rm -rf ~/

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SusanK @susankleinfelter.bsky.social · 3d

Bridges math art is on my bucket list #sciart

robertfathauer.bsky.social @robertfathauer.bsky.social · 4d

This weekend would be a great time to submit your art for the exhibition to be held at the Joint Mathematics Meetings. Take advantage of this opportunity to share your work with over 5000 attendees this January in Washington, DC. You’ll need to submit by the 15th at gallery.bridgesmathart.org.

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Science Magazine @science.org · 4d

“We can continue accelerating toward an AI-powered future that amplifies existing inequities, or we can deliberately steer toward one that increases prospects for shared global prosperity,” writes Chinasa T. Okolo in a new #ScienceExpertVoices article. https://scim.ag/46JkNka

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SusanK @susankleinfelter.bsky.social · 3d

Giant Pikachu bouncy house where children climb in and out through the vagina

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Çağrı Çevrim @cagricevrim.bsky.social · 5d

I’m thrilled to share my postdoc work and the first paper from the McKinley Lab! 🎉
@karalmckinley.bsky.social
We built the first transgenic model of menstruation in mice.
We used it to uncover how the endometrium organizes and sheds during menstruation. 🧪
www.biorxiv.org/content/10.1...
🧵

Induction of menstruation in mice reveals the regulation of menstrual shedding

During menstruation, an inner layer of the endometrium is selectively shed, while an outer, progenitor-containing layer is preserved to support repeated regeneration. Progress in understanding this co...

www.biorxiv.org

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STCmicrobeblog @stcmicrobeblog.bsky.social · 5d

𝘗𝘴𝘦𝘶𝘥𝘰𝘮𝘰𝘯𝘢𝘴 fans take note 👇

"𝘗. 𝘢𝘦𝘳𝘶𝘨𝘪𝘯𝘰𝘴𝘢 senses EPS trails using type IV pili and adhesins during biofilm formation"

www.nature.com/articles/s41...
#MicroSky

figure from https://www.nature.com/articles/s41564-025-02087-4

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Levayer Lab @levayerr.bsky.social · 6d

Happy to share the last version of our story @currentbiology.bsky.social on the role of interfacial tension in mechanical cell competition led by @leovalon.bsky.social and Alexis Matamoro Vidal
www.sciencedirect.com/science/arti...

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SusanK @susankleinfelter.bsky.social · 6d

Woohoo! Go Foldit!

Structural Biology @actacrystd.iucr.org · 6d

Andreas C. Petrides et al.: Reconstructing biological molecules with help from video gamers ##Foldit##PDBREDO##CitizenScience@umassd...##IUCrhttps://journals.iucr.org/paper?S2059798325008149

Reconstructing biological molecules with help from video gamers

The results of the Foldit citizen science puzzles for crystallographic models and their integration into the PDB-REDO databank are discussed.

journals.iucr.org

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Chise @sailorrooscout.bsky.social · 7d

GOOD NEWS! Researchers have discovered a powerful antibody, known as 04_A06, that is able to neutralize 98.5% of MORE THAN 300 different HIV strains AND permanently reduce HIV viral load to undetectable levels, making it one of the broadest-acting antibodies against HIV identified to date.

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Alt CDC (they/them) @altcdc.altgov.info · 6d

Laughter is medicine. G’night all

Dr. Lucky Tran @luckytran.com · 7d

🎵 They did the Monster Slash 😭 @ellecordova.bsky.social

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bioRxiv Cell Biology @biorxiv-cellbio.bsky.social · 6d

Optogenetic construction of de novo integrin-adhesion complexes reveals role for biocondensation in adhesion nucleation https://www.biorxiv.org/content/10.1101/2025.10.08.681107v1

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Roni Odai @rodai.bsky.social · 13d

Viral AlphaFold Database (VAD) is live in Science Advances

~27,000 predicted viral protein monomers & homodimers

Conserved folds across bacteria, archaea & eukaryotic viruses

New toxin–antitoxin system KreTA uncovered

Vast “functional darkness” remains uncharted

www.science.org/doi/10.1126/...

The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes

VAD is a Viral AlphaFold Database of protein monomers and homodimers from viruses infecting hosts across the tree of life.

www.science.org

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Carl Zimmer @carlzimmer.com · 6d

Today my @nytimes.com colleagues and I are launching a new series called Lost Science. We interview US scientists who can no longer discover something new about our world, thanks to this year‘s cuts. Here is my first interview with a scientist who studied bees and fires. Gift link: nyti.ms/3IWXbiE

nyti.ms

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