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Beth Cimini 🔬💻📊

@bethcimini.bsky.social

3.3K followers 3.3K following 1.3K posts

She/her. I turn pictures into numbers so others can turn them into medicine. Also I yell about politics a lot. See the fantastic things my team does at https://ciminilab.github.io/WeMakeStuff . Views my own, awesome science from my amazing team.

ciminilab.github.io

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Beth Cimini 🔬💻📊 @bethcimini.bsky.social · Nov 12

The highs of the conference yesterday and advising people on Twitter this morning have made me a bit reflective - I want to share some stuff I've never put online before, in case it helps others out.

In grad school, by any measure of academic success, I was a complete failure.

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BioImaging North America @bioimagingna.bsky.social · 11d

#HappyFluorescenceFriday!

#microscopycommunity- Join us for Image Analysis Journeys from Academia to Industry featuring Caroline Miller, Kevin Murphy, Jian Wei Tay, Erick Ratamero, Sara McArdle, and Sripad Ram. Nov 6, 1:00 to 2:30 pm ET

More info & registration: buff.ly/eFUU6up

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Beth Cimini 🔬💻📊 @bethcimini.bsky.social · 6h

Episode 16 - Learn more about the Cell Painting Gallery, a free repository of nearly a petabyte of images and imaging data, curated by the incredibly talented @erinweisbart.bsky.social . Truly a goldmine for big-data lovers everywhere!

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derek guy @dieworkwear.bsky.social · 1d

It's hard to help Americans left behind because so much of US identity is rooted in individualism. The average American conservative holds all three positions at once:

— Virtue signals about supporting US manufacturing
— Against raising the minimum wage
— Buys foreign imports because they're cheap

HardPass4 on Twitter tweets: "I'm willing to pay more for quality products if they are made in America, by Americans, who are paid a decent income." The tweet shows Norman Rockwell's "Freedom of Speech" painting, which is often used to show the tweeter is expressing a brave opinion.

HardPass4 on Twitter tweets: "MINIMUM WAGE JOBS WERE NOT MEANT TO BE A CAREER. Why does no one understand this? Entry level jobs are STEPPING STONES to better jobs. No one wants to work towards that though."

HardPass4 on Twitter tweets: "Buy $5 gloves instead of $50 ones. Trust me." The tweet shows a box of "Gorilla Grip" gloves.

The label on Gorilla Grip gloves show they're made in China.

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Faine Greenwood @faineg.bsky.social · 20h

These people really don't grasp the connection between "gleefully forcing a bunch of highly educated and highly motivated people out of their jobs" and "those people now have a lot of free time and hate you even more than they did before," do they

Aaron Rupar @atrupar.com · 1d

Sean Duffy: "The No Kings protest, Maria, really frustrating. This is part of antifa, paid protesters. It begs the question who's funding it."

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Andrew Lawrence @ndrew.bsky.social · 3d

every single tech idea is like “soon our robots will be capable of playing catch with your kid, freeing you up to spend more time working on your employers’ spreadsheets”

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bleary @bleary.off-the-records.com · 23h

If anyone needs me I will be in the museum, lying down next to the bog bodies.

Did people really memorize phone numbers before cell phones, or is that just a movie thing?
2? Questions
I was watching some old shows from the 90s and noticed people would just dial numbers from memory - like they'd call their friends or family without looking anything up.
Made me wonder if that was actually normal back then? Did people genuinely have all their important numbers memorized, or did most folks keep a little address book or written list nearby?

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Brandon Friedman @brandonfriedman.bsky.social · 1d

Promoting the editor-in-chief's personal side project. Zero named sources in a story that promotes the editor-in-chief's personal political position. Misspelling the subject's name. It took one day for CBS News to become a conservative blog.

www.cbsnews.com/video/some-n...

CBS News: Some NYPD officers worry about Mandani becoming NYC mayor the Free Press reports.

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Kai Ryssdal @kairyssdal.bsky.social · 1d

Wut?

Aaron Rupar @atrupar.com · 1d

Bessent: "No Kings means no paychecks. No paychecks and no government."

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Bobby Kogan @bbkogan.bsky.social · 1d

Truly can’t believe they took this quote
www.thebulwark.com/p/the-other-...

"They keep saying as loudly as possible, we're going to do more illegal partisan impoundments, and I think Democrats are seeing this and it just reinforces their sense they can't negotiate with these guys," Bobby Kogan, senior director of federal budget policy at the Center for American Progress, told me. "It's Darth Vader saying 'I have altered the deal, pray I don't alter it any further'—again and again and again."

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Faine Greenwood @faineg.bsky.social · 1d

Mods are asleep post brassicas

You either die a brassica or you live long enough to see yourself become a crab.

CAP'N
CRUNCH'S
DOPSIAll
NATURALLY &
ARTIFICIALLY
Brassica oleracea
otened
cer

What vegetable are you?
I'm brassica oleracea
Do you have the slightest idea how little that narrows it down?

Brassica oleracea

Ladies, get you a fella who can do it all

Selection for terminal buds
Selection for lateral buds
Selection for stem
Selection for leaves
Selection for stems and flowers
Selection for flower clusters
Cabbage
Brussels sprouts
Kohlrabi
Kale
Broccoli
Cauliflower

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Dr. Stephanie @punkrockscience.bsky.social · 1d

The data’s in Excel.

Marjorie James Keenan @unenthusiast.com · 2d

In honour of spooky month, share a 4 word horror story that only someone in your profession would understand.

rm -rf ~/

hammancheez @hammancheez.bsky.social · 2d

"The chancellor approved it"

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Giulia Bertolin @bertolingiulia.bsky.social · 1d

Excited to share our #BioSenSRRF preprint on bioRxiv! 🎉
We show how SRRF microscopy can be used with FRET-based biosensors to 🔬mitochondrial functions with high resolution 😍.
Code and test data are open (GitHub + Zenodo).
👏 to Nicolas, Pierre-Jean, and co-authors! www.biorxiv.org/content/10.1...

Combining FRET and super-resolution microscopy reveals kinase activation and mitochondrial activity at the nanoscale

Protein kinases are key regulators of intracellular signaling, showing activities in specific subcellular compartments and in micro- or nano-domains. Genetically encoded biosensors based on Förster′s ...

www.biorxiv.org

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Jacob T. Levy @jacobtlevy.bsky.social · 1d

Good Place:

Fun fact: Columbus is in the Bad Place
because of all the raping, slave trade, and genocide.

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Beth Cimini 🔬💻📊 @bethcimini.bsky.social · 1d

Or spookier even: make that `tensorflow<2`

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Beth Cimini 🔬💻📊 @bethcimini.bsky.social · 1d

Cloud egress 1 petabyte

OR

50M files, no metadata

OR

Tensorflow/Torch shared environment

Marjorie James Keenan @unenthusiast.com · 2d

In honour of spooky month, share a 4 word horror story that only someone in your profession would understand.

rm -rf ~/

hammancheez @hammancheez.bsky.social · 2d

"The chancellor approved it"

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AnnaClimbsMtns🔱 @annaclimbsmtns.bsky.social · 3d

Is your team no longer in the MLB postseason? Want to hop on the Mariners bandwagon? We will welcome you with open arms! Here are some reasons why you should join us.
- We've never been to the WS, let alone won it.
- Our best player has a nickname celebrating his big ass.

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Carl T. Bergstrom @carlbergstrom.com · 2d

Thankfully, some of yesterday's CDC firings have been rescinded.

But this should be a major scandal, not business as usual in this shitshow of an administration. It's either spectacular incompetence or an effort to make even politically untouchable positions feel precarious to those in them.

Helen Branswell 🇨🇦 @helenbranswell.bsky.social · 2d

100s of #CDC employees were notified Friday they were being fired — RIF'd. The firings cross multiple parts of the agency, endangering its core mission of keeping Americans safe.
Saturday, some were informed they were RIF'd in error.
Hard to imagine how this happens www.statnews.com/2025/10/11/c...

CDC battered by government shutdown firings, while some are rescinded

The White House’s mass firing of CDC staff on Friday has decimated offices related to injury prevention, respiratory disease surveillance, and chronic disease, according to four people familiar with t...

www.statnews.com

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Pavel @spavel.bsky.social · 2d

bitch what

Onedrive settings. A toggle for using AI to detect and identify faces is set to on. The caption says, you can only turn off this setting 3 times per year.

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Anne Carpenter @drannecarpenter.bsky.social · 4d

15 years in the making, we confirmed that mitochondria - the powerhouse of the cell - have an unusual localization in patients who experience psychosis (including schizophrenia and bipolar disorders). You’ll never guess what kind of patient cells we used to make this discovery… 🧵

mitochondria from bipolar patients are closer to the nucleus in these images; control patients' are spread out further

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Coleen Murphy @ctmurphy1.bsky.social · 4d

Begging scientists (and media posts about science) to stop using ChatGPT-generated images

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Brendan Nyhan @brendannyhan.bsky.social · 4d

Every targeted institution (my own very much included) should cut and paste this letter onto their letterhead.

Kathleen Clark @kathleenclark.bsky.social · 4d

A master class from MIT in responding to authoritarian overreach:

Your “premise … is inconsistent with our core belief that scientific funding should be based on scientific merit alone.
… America’s leadership in science & innovation depends on independent thinking & open competition for excellence.

Dear Madam Secretary,
I write in response to your letter of October 1, inviting MIT to review a "Compact for Academic Excellence in Higher Education." I acknowledge the vital importance of these matters.
I appreciated the chance to meet with you earlier this year to discuss the priorities we share for American higher education.
As we discussed, the Institute's mission of service to the nation directs us to advance knowledge, educate students and bring knowledge to bear on the world's great challenges.
We do that in line with a clear set of values, with excellence above all. Some practical examples:
• MIT prides itself on rewarding merit. Students, faculty and staff succeed here based on the strength of their talent, ideas and hard work. For instance, the Institute was the first to reinstate the SAT/ACT requirement after the pandemic. And MIT has never had legacy preferences in admissions.
• MIT opens its doors to the most talented students regardless of their family's finances. Admissions are need-blind. Incoming undergraduates whose families earn less than $200,000 a year pay no tuition. Nearly 88% of our last graduating class left MIT with no debt for their education. We make a wealth of free courses and low-cost certificates available to any American with an internet connection. Of the undergraduate degrees we award, 94% are in STEM fields. And in service to the nation, we cap enrollment of international undergraduates at roughly 10%.

source:
https://orgchart.mit.edu/letters/regarding-compact

• We value free expression, as clearly described in the MIT Statement on Freedom of Expression and Academic Freedom. We must hear facts and opinions we don't like - and engage respectfully with those with whom we disagree.
These values and other MIT practices meet or exceed many standards outlined in the document you sent. We freely choose these values because they're right, and we live by them because they support our mission - work of immense value to the prosperity, competitiveness, health and security of the United States. And of course, MIT abides by the law.
The document also includes principles with which we disagree, including those that would restrict freedom of expression and our independence as an institution. And fundamentally, the premise of the document is inconsistent with our core belief that scientific funding should be based on scientific merit alone.
In our view, America's leadership in science and innovation depends on independent thinking and open competition for excellence. In that free marketplace of ideas, the people of MIT gladly compete with the very best, without preferences. Therefore, with respect, we cannot support the proposed approach to addressing the issues facing higher education.
As you know, MIT's record of service to the nation is long and enduring. Eight decades ago, MIT leaders helped invent a scientific partnership between America's research universities and the U.S. government that has delivered extraordinary benefits for the American people. We continue to believe in the power of this partnership to serve the nation.
Sincerely,
Sally Kornbluth

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Turku BioImaging @turkubioimaging.bsky.social · 4d

🚀Join Helsinki BioImaging as an Image Analysis Specialist🖥️to support cross-disciplinary image analysis projects. If you love coding and are interested in working at the crossroads of computer science and biology, apply by 🗓️ November 15, 2025⤵️
jobs.helsinki.fi/job/Helsinki...
#jobopening

Image Analysis Specialist/Engineer/Coordinator, Helsinki Bioimaging

jobs.helsinki.fi

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Josh Moody @byjoshmoody.bsky.social · 4d

MIT rejects "compact" proposed by the Trump administration.
MIT prez wrote: it "would restrict freedom of expression and our independence as an institution" and "is inconsistent with our core belief that scientific funding should be based on scientific merit alone."
orgchart.mit.edu/letters/rega...

Regarding the Compact | MIT Organization Chart

orgchart.mit.edu

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Brendan Keogh @brkeogh.bsky.social · 4d

I still think the most accurate and consistent way to think about generative AI is that, in every instance, people exclusively use it for tasks that they don't have any respect for or give a shit about.

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lastpositivist.bsky.social @lastpositivist.bsky.social · 4d

you know what fair

Bootleggirl on twitter writes: "I still dislike the Star Wars sequels but I can't no longer fault them for running with the premise of "20 years after fascism, same fascism again, but stupider" bc I just lived through that.

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