@single-molecule.bsky.social
Electronic Genome mapper (EGM) using Nabsys OhmX, NGS, DNA, genomics, structural variants, fact-based politics, a little sports
If Schumer won't step aside, he needs to be pushed aside. This process was an abomination. If my Democratic senators (Whitehouse and Reed) won't replace Schumer, we need to replace them with senators who will.
We won't be successful fighting Trump with Schumer/Durban in party leadership positions. Now is the time to put leaders in place who understand the fight we're in.
Will you call for Schumer to step aside?
Will you call for Schumer to step aside?
November 11, 2025 at 1:09 AM
If Schumer won't step aside, he needs to be pushed aside. This process was an abomination. If my Democratic senators (Whitehouse and Reed) won't replace Schumer, we need to replace them with senators who will.
I don't like to speak ill of the dead. Thanks for doing it for me.
Yes, some people's legacies are complicated. For example, Watson. After all, though he was racist, don't forget his other traits. For example, he was also sexist. And also anti-semitic. And a data / idea thief. So let's not forget all the different facets.
November 8, 2025 at 1:24 PM
I don't like to speak ill of the dead. Thanks for doing it for me.
Reposted
Study hard today. Pop quiz after potluck!
November 2, 2025 at 7:08 PM
Study hard today. Pop quiz after potluck!
Reposted
Exactly what you said. A lot of people are the same but a lot of people are also missing
There was a discussion on LinkedIn yesterday about the good days of Academic Twitter before everything went to crap and we left. I'm curious why we haven't been able to recreate that here. A lot of the same folks are here, but there's not as much engagement. What's Bluesky missing? ⚛️🧪
November 2, 2025 at 3:53 PM
Exactly what you said. A lot of people are the same but a lot of people are also missing
Reposted
To shameless quote my own piece, “The legacy media is apparently more interested in the climate musings of an erstwhile PC mogul than a sober assessment by the world’s leading climate scientists.”
October 31, 2025 at 10:12 PM
To shameless quote my own piece, “The legacy media is apparently more interested in the climate musings of an erstwhile PC mogul than a sober assessment by the world’s leading climate scientists.”
Reposted
If a temporary resident of the White House can totally demolish the East Wing to build a gaudy ballroom, without any authority, approval, or regulation, he can tear down the rest of the White House to build a Walmart. That this destruction is allowed underscores how off the rails our country is now.
October 24, 2025 at 7:35 PM
If a temporary resident of the White House can totally demolish the East Wing to build a gaudy ballroom, without any authority, approval, or regulation, he can tear down the rest of the White House to build a Walmart. That this destruction is allowed underscores how off the rails our country is now.
A great letter!
www.thedailybeast.com/a-strongly-w...
www.thedailybeast.com/a-strongly-w...
A Strongly Worded Letter From Donald Trump’s HOA
From one president to another, there are some property violations to address.
www.thedailybeast.com
October 22, 2025 at 8:19 PM
A great letter!
www.thedailybeast.com/a-strongly-w...
www.thedailybeast.com/a-strongly-w...
Reposted
Italy to get 4 billion euros in 2026 from banks, insurers reut.rs/4oB5AaU
Italy to get 4 billion euros in 2026 from banks, insurers
Italy plans to garner around 4 billion euros ($4.66 billion) next year from its banks and insurers through a package of measures contained in the government's 2026 budget, Economy Minister Giancarlo Giorgetti said on Wednesday.
reut.rs
October 22, 2025 at 4:25 PM
Italy to get 4 billion euros in 2026 from banks, insurers reut.rs/4oB5AaU
Sunrise the day after millions protested the impending dictatorship. Many media confused thousands with millions. My local paper printed no local coverage despite 30,000 marching a block from their office. @providencejournal.bsky.social should not wonder why circulation continues to drop
October 19, 2025 at 1:52 PM
Sunrise the day after millions protested the impending dictatorship. Many media confused thousands with millions. My local paper printed no local coverage despite 30,000 marching a block from their office. @providencejournal.bsky.social should not wonder why circulation continues to drop
I don’t know how many thousands were at the providence rally today because there were too many to ever fit into a photo. Must have been more than 10K but don’t know how many more
October 18, 2025 at 7:45 PM
I don’t know how many thousands were at the providence rally today because there were too many to ever fit into a photo. Must have been more than 10K but don’t know how many more
Reposted
Johnson, Emmer and Marshall denounce the No Kings rallies as something arranged by the "terrorist wing" of the Democratic Party. This is outrageous. Express your response in the time-honored way. Go to the rally. I'll be there next Saturday. www.nokings.org
No Kings
As the president escalates his authoritarian power grab, the NO KINGS non-violent movement continues to rise stronger. We are united once again to remind the world: America has No Kings and the power ...
www.nokings.org
October 11, 2025 at 2:05 PM
Johnson, Emmer and Marshall denounce the No Kings rallies as something arranged by the "terrorist wing" of the Democratic Party. This is outrageous. Express your response in the time-honored way. Go to the rally. I'll be there next Saturday. www.nokings.org
Both my wife and I got double-vaxed yesterday, flu and Covid. I feel safer already and sorry for those who have been duped by RFK Jr and his deadly anti-vax friends. There is no safer, better preventative than a vaccine. We should be encouraging vaccinations, not making it difficult to get them
October 7, 2025 at 3:03 AM
Both my wife and I got double-vaxed yesterday, flu and Covid. I feel safer already and sorry for those who have been duped by RFK Jr and his deadly anti-vax friends. There is no safer, better preventative than a vaccine. We should be encouraging vaccinations, not making it difficult to get them
Reposted
If this country was truly “pro-life,” we would have Medicare for All, a Green New Deal, gun reform, universal child care, and a living wage.
The right-wing agenda isn’t about “life.”
It’s about control.
The right-wing agenda isn’t about “life.”
It’s about control.
October 2, 2025 at 6:45 PM
If this country was truly “pro-life,” we would have Medicare for All, a Green New Deal, gun reform, universal child care, and a living wage.
The right-wing agenda isn’t about “life.”
It’s about control.
The right-wing agenda isn’t about “life.”
It’s about control.
firstwordhealthtech.com/story/6228854
#Nabsys will be well represented at #ASHG25 in two weeks in Boston. I will be presenting my own poster on Friday but also available to discuss posters on repeat expansions and use of CRISPR to customize EGM for genomic assays that are otherwise impossible
#Nabsys will be well represented at #ASHG25 in two weeks in Boston. I will be presenting my own poster on Friday but also available to discuss posters on repeat expansions and use of CRISPR to customize EGM for genomic assays that are otherwise impossible
firstwordhealthtech.com
October 2, 2025 at 7:01 PM
firstwordhealthtech.com/story/6228854
#Nabsys will be well represented at #ASHG25 in two weeks in Boston. I will be presenting my own poster on Friday but also available to discuss posters on repeat expansions and use of CRISPR to customize EGM for genomic assays that are otherwise impossible
#Nabsys will be well represented at #ASHG25 in two weeks in Boston. I will be presenting my own poster on Friday but also available to discuss posters on repeat expansions and use of CRISPR to customize EGM for genomic assays that are otherwise impossible
The up escalator at the Eagle Rock Target was broken today, forcing my wife and me to walk up. I expect an investigation and inclusion in the escalator files, never to be released.
September 27, 2025 at 11:29 PM
The up escalator at the Eagle Rock Target was broken today, forcing my wife and me to walk up. I expect an investigation and inclusion in the escalator files, never to be released.
Was walking around Harvard and saw this. Things have not gotten better in 62 years
September 23, 2025 at 11:12 AM
Was walking around Harvard and saw this. Things have not gotten better in 62 years
Reposted
September 18, 2025 at 3:34 PM
Reposted
Turning off the fire alarms won’t prevent the fire.
US Treasury-led watchdog dismantles climate advisory panels
U.S. financial regulators voted on Wednesday to disband two committees charged with monitoring financial risks brought on by climate change, ending a multi-year Biden administration effort to embed climate threats into financial regulations.
www.reuters.com
September 13, 2025 at 5:23 PM
Turning off the fire alarms won’t prevent the fire.
#AGBTPH25 JY: Can do all by all testing of compounds x cancer models. 50 cancer models, 1200 drug treatments, 60K experiments, 100M cells
September 10, 2025 at 10:53 PM
#AGBTPH25 JY: Can do all by all testing of compounds x cancer models. 50 cancer models, 1200 drug treatments, 60K experiments, 100M cells
#AGBTPH25 JK: Could apply functional data to reclassify 682 VUS. Look at All of Us data, rare LOF missense have higher risk of cancer. AlphaMissense prediction calls too many variants pathogenic
September 10, 2025 at 10:41 PM
#AGBTPH25 JK: Could apply functional data to reclassify 682 VUS. Look at All of Us data, rare LOF missense have higher risk of cancer. AlphaMissense prediction calls too many variants pathogenic
#AGBTPH25 JK: Lynch syndrome is first inherited cancer risk syndrome, LOF in DNA mismatch repair genes. Most are missense with most being VUS. Apply 6-TG to cells to select MMR- proteins. Mapped 73,568 missense variants. Most have no effect but there are hot spots for impact
September 10, 2025 at 10:37 PM
#AGBTPH25 JK: Lynch syndrome is first inherited cancer risk syndrome, LOF in DNA mismatch repair genes. Most are missense with most being VUS. Apply 6-TG to cells to select MMR- proteins. Mapped 73,568 missense variants. Most have no effect but there are hot spots for impact