Roser TP
@rosertp.bsky.social
Postdoc in the Vinuesa at the Crick. Former PhD in the Hepworth Lab and MSc in the Cerutti lab. I just really like immunology ✊🏽🚩💜
Reposted by Roser TP
S-TIR-ring up TLR7 and TLR9: signaling domain substitutions clarify the TLR paradox: www.jci.org/articles/vie...
@rosertp.bsky.social & @carovinuesa.bsky.social provide a Commentary on Claire Leibler et al.: www.jci.org/articles/vie...
@rosertp.bsky.social & @carovinuesa.bsky.social provide a Commentary on Claire Leibler et al.: www.jci.org/articles/vie...
November 14, 2025 at 7:30 PM
S-TIR-ring up TLR7 and TLR9: signaling domain substitutions clarify the TLR paradox: www.jci.org/articles/vie...
@rosertp.bsky.social & @carovinuesa.bsky.social provide a Commentary on Claire Leibler et al.: www.jci.org/articles/vie...
@rosertp.bsky.social & @carovinuesa.bsky.social provide a Commentary on Claire Leibler et al.: www.jci.org/articles/vie...
Reposted by Roser TP
Our new publication on BCR sequencing in ME/CFS, adding to the evidence of an increased usage of IGHV3-30.
Much more immunological research is needed to understand the many lines of evidence indicating immune-mediated or autoimmune components to the disease.
www.frontiersin.org/journals/imm...
Much more immunological research is needed to understand the many lines of evidence indicating immune-mediated or autoimmune components to the disease.
www.frontiersin.org/journals/imm...
Frontiers | Deep sequencing of BCR heavy chain repertoires in myalgic encephalomyelitis/chronic fatigue syndrome
www.frontiersin.org
February 17, 2025 at 7:23 AM
Our new publication on BCR sequencing in ME/CFS, adding to the evidence of an increased usage of IGHV3-30.
Much more immunological research is needed to understand the many lines of evidence indicating immune-mediated or autoimmune components to the disease.
www.frontiersin.org/journals/imm...
Much more immunological research is needed to understand the many lines of evidence indicating immune-mediated or autoimmune components to the disease.
www.frontiersin.org/journals/imm...
Reposted by Roser TP
Tejedor Vaquero, Neuman et al. @gmagrilab.bsky.social demonstrate immunomolecular and reactivity landscapes of gut IgA subclasses in homeostasis and inflammatory bowel disease. https://buff.ly/4jVJYV5
📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r
📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r
February 21, 2025 at 6:20 PM
Tejedor Vaquero, Neuman et al. @gmagrilab.bsky.social demonstrate immunomolecular and reactivity landscapes of gut IgA subclasses in homeostasis and inflammatory bowel disease. https://buff.ly/4jVJYV5
📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r
📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r
Reposted by Roser TP
McClure, @hepworth-lab.bsky.social, Konkel et al. outline a Th17-to-Tfh plasticity during #periodontitis that is protective and limits periodontal pathology. https://buff.ly/41fwVq4
📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r
📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r
February 18, 2025 at 6:14 PM
McClure, @hepworth-lab.bsky.social, Konkel et al. outline a Th17-to-Tfh plasticity during #periodontitis that is protective and limits periodontal pathology. https://buff.ly/41fwVq4
📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r
📘 In Host–Microbe Interactions 2025 👉 https://buff.ly/40XMv8r
Reposted by Roser TP
Wondering if you should get up early for your vaccine for the best immune response? Kai-Michael Tollner's recent paper with the University of Birmingham says don't bother if you're under 60!
Time of day of vaccination does not influence antibody responses to pneumococcal and annual influenza vaccination in a cohort of healthy older adults - PubMed
Vaccines are less immunogenic in older adults, partly due to immunosenescence. Having previously shown that morning influenza vaccination may be more immunogenic in older adults (mean age 71), we…
buff.ly
February 17, 2025 at 9:28 AM
Wondering if you should get up early for your vaccine for the best immune response? Kai-Michael Tollner's recent paper with the University of Birmingham says don't bother if you're under 60!
Reposted by Roser TP
Grateful to see @retractionwatch.com share our story! Learn more about the launch of Journal of Human Immunity, why our editors made the move, and what’s next for our nonprofit journal with @rupress.org. Insights from our EiC @casanovalab.bsky.social here: retractionwatch.com/2025/02/06/e...
Editors resign from Springer immunology journal to launch nonprofit title
Several top editors of the Journal of Clinical Immunology, a Springer Nature title, have jumped ship to start a new, nonprofit journal with Rockefeller University Press. Jean-Laurent Casanova…
retractionwatch.com
February 6, 2025 at 8:36 PM
Grateful to see @retractionwatch.com share our story! Learn more about the launch of Journal of Human Immunity, why our editors made the move, and what’s next for our nonprofit journal with @rupress.org. Insights from our EiC @casanovalab.bsky.social here: retractionwatch.com/2025/02/06/e...
Reposted by Roser TP
Our very own Laura Shuttleworth talked about her brilliant research last night at the @crick.ac.uk for Sofar Sounds, sharing the stage with musicians and poets, and bringing science closer to society.
February 6, 2025 at 3:36 PM
Our very own Laura Shuttleworth talked about her brilliant research last night at the @crick.ac.uk for Sofar Sounds, sharing the stage with musicians and poets, and bringing science closer to society.
Reposted by Roser TP
Are you a parent? Or caring for another adult, relative, friend? And are you a UK-based #academic? 🧪
We recently ran a survey (www.qualtrics.manchester.ac.uk/jfe/form/SV_...) to capture lived experiences - if you didn't complete the survey at the time, please do now. Please share w/ colleagues
We recently ran a survey (www.qualtrics.manchester.ac.uk/jfe/form/SV_...) to capture lived experiences - if you didn't complete the survey at the time, please do now. Please share w/ colleagues
Carers in STEMM: Caring Responsibilities
Are you a UK-based academic or student balancing your role as a caregiver with your research? We want to hear your lived experiences!
www.qualtrics.manchester.ac.uk
January 15, 2025 at 10:19 AM
Are you a parent? Or caring for another adult, relative, friend? And are you a UK-based #academic? 🧪
We recently ran a survey (www.qualtrics.manchester.ac.uk/jfe/form/SV_...) to capture lived experiences - if you didn't complete the survey at the time, please do now. Please share w/ colleagues
We recently ran a survey (www.qualtrics.manchester.ac.uk/jfe/form/SV_...) to capture lived experiences - if you didn't complete the survey at the time, please do now. Please share w/ colleagues
Reposted by Roser TP
Working in Antarctica, scientists have drilled the world’s oldest continuous ice core, 2690 meters long and holding an unbroken history of the atmosphere going back 1.2 million years.
Learn more in this week’s News at a glance. ⬇️
Learn more in this week’s News at a glance. ⬇️
News at a glance: Oldest continuous ice core, formaldehyde's risks, and building Africa's science workforce
The latest in science and policy
scim.ag
January 17, 2025 at 5:07 PM
Working in Antarctica, scientists have drilled the world’s oldest continuous ice core, 2690 meters long and holding an unbroken history of the atmosphere going back 1.2 million years.
Learn more in this week’s News at a glance. ⬇️
Learn more in this week’s News at a glance. ⬇️
Reposted by Roser TP
This is a super interesting (IMO) study on how T cells can repress out of control B cell responses, particularly relevant to autoimmunity and lymphomagenesis #Immunosky #lymphomasky
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Hyperreactive B cells instruct their elimination by T cells to curb autoinflammation and lymphomagenesis
Aberrant immune signal strength in B cells is associated with autoimmune diseases
and lymphoma. Diehl et al. show that hyperreactive B cells trigger cytotoxic T cell-mediated
elimination. Less reactiv...
www.cell.com
January 16, 2025 at 7:24 PM
This is a super interesting (IMO) study on how T cells can repress out of control B cell responses, particularly relevant to autoimmunity and lymphomagenesis #Immunosky #lymphomasky
www.cell.com/immunity/ful...
www.cell.com/immunity/ful...
Reposted by Roser TP
We’re thrilled to announce our partnership with the International Alliance for Primary Immunodeficiency Societies (#IAPIDS) to launch the Journal of Human Immunity (JHI) @jhumimmunity.org (https://buff.ly/3PAEMrK)! Groundbreaking, #OpenAccess research on #HumanImmunity 👉 https://buff.ly/4ajqm8W
January 16, 2025 at 4:00 PM
We’re thrilled to announce our partnership with the International Alliance for Primary Immunodeficiency Societies (#IAPIDS) to launch the Journal of Human Immunity (JHI) @jhumimmunity.org (https://buff.ly/3PAEMrK)! Groundbreaking, #OpenAccess research on #HumanImmunity 👉 https://buff.ly/4ajqm8W
Reposted by Roser TP
There's a lot of replies to our new paper talking about how capitalism or overpopulation are the real enemy. Without getting into whether that's true of the climate emergency or the sixth mass extinction (🙃), I want to briefly explain why pandemics are different. www.nature.com/articles/s44...
Pathogens and planetary change - Nature Reviews Biodiversity
This Review explores the relationship between emerging infectious diseases and biodiversity loss, and how both are connected to global environmental changes in the Anthropocene.
www.nature.com
January 16, 2025 at 6:15 PM
There's a lot of replies to our new paper talking about how capitalism or overpopulation are the real enemy. Without getting into whether that's true of the climate emergency or the sixth mass extinction (🙃), I want to briefly explain why pandemics are different. www.nature.com/articles/s44...
Reposted by Roser TP
David Lynch, Twin Peaks and Muholland Drive director, dies aged 78
David Lynch, Twin Peaks and Muholland Drive director, dies aged 78
Film-maker who specialised in surreal, noir style mysteries made a string of influential, critically acclaimed works including Wild at Heart and Eraserhead
David Lynch, the maverick American director who sustained a successful mainstream career while…
www.theguardian.com
January 16, 2025 at 6:43 PM
David Lynch, Twin Peaks and Muholland Drive director, dies aged 78
Reposted by Roser TP
Bad news for climate just announced! In 2024, Earth's average temperature temporarily exceeded 1.5°C above pre-industrial levels for the first time. This breach highlights accelerating climate risks - toward the end of the "safe zone" defined by the Paris Agreement.🧪🌐🌍
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Earth breaches 1.5 °C climate limit for the first time: what does it mean?
The threshold has been exceeded for only one year so far, but humanity is nearing the end of what many thought was a ‘safe zone’ as climate change worsens.
www.nature.com
January 10, 2025 at 8:08 PM
Bad news for climate just announced! In 2024, Earth's average temperature temporarily exceeded 1.5°C above pre-industrial levels for the first time. This breach highlights accelerating climate risks - toward the end of the "safe zone" defined by the Paris Agreement.🧪🌐🌍
www.nature.com/articles/d41...
www.nature.com/articles/d41...
Reposted by Roser TP
What a great way to start this account and end the week: our preprint describing how dermal γδ T cells mediate a skin-lung axis during parasite infection in mice is online! I'm excited to show the findings of my main postdoc project with @profjudiallen.bsky.social!🧵👇
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Migratory dermal gamma delta T cells determine the balance between lung immunity and tissue damage during Nippostrongylus brasiliensis infection
Many helminth parasites migrate through multiple host organs during infection but how immunity is regulated across these tissues is still poorly understood. To investigate the cellular and molecular a...
www.biorxiv.org
January 10, 2025 at 3:48 PM
What a great way to start this account and end the week: our preprint describing how dermal γδ T cells mediate a skin-lung axis during parasite infection in mice is online! I'm excited to show the findings of my main postdoc project with @profjudiallen.bsky.social!🧵👇
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Roser TP
Global sea-ice extent ranked by month from 1979 through 2024.
Nothing blue since since 2015!
Within the recent nine years, every month has experienced a record-low extent.
🌊🧪⚒️📉
Nothing blue since since 2015!
Within the recent nine years, every month has experienced a record-low extent.
🌊🧪⚒️📉
January 2, 2025 at 7:33 AM
Global sea-ice extent ranked by month from 1979 through 2024.
Nothing blue since since 2015!
Within the recent nine years, every month has experienced a record-low extent.
🌊🧪⚒️📉
Nothing blue since since 2015!
Within the recent nine years, every month has experienced a record-low extent.
🌊🧪⚒️📉
Reposted by Roser TP
AI data centers are multiplying across the U.S. and sucking up huge amounts of power.
New evidence shows they may also be distorting the normal flow of electricity for millions of Americans
New evidence shows they may also be distorting the normal flow of electricity for millions of Americans
AI Needs So Much Power, It’s Making Yours Worse
There’s a strong link between proximity to AI data centers and higher levels of distorted power in residential areas
www.bloomberg.com
December 27, 2024 at 8:30 PM
AI data centers are multiplying across the U.S. and sucking up huge amounts of power.
New evidence shows they may also be distorting the normal flow of electricity for millions of Americans
New evidence shows they may also be distorting the normal flow of electricity for millions of Americans
Reposted by Roser TP
Not only will this create a network effect, but because bioRxiv is intended to be an enabling platform that stimulates evolution, it will allow _other people_ to do great things e.g. connect.biorxiv.org/news/2021/05... 2/2
An easy access dashboard now provides links to scientific discussion and evaluation of bioRxiv preprints.
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
connect.biorxiv.org
December 21, 2024 at 2:05 PM
Not only will this create a network effect, but because bioRxiv is intended to be an enabling platform that stimulates evolution, it will allow _other people_ to do great things e.g. connect.biorxiv.org/news/2021/05... 2/2
Reposted by Roser TP
Hi 👋🏼 The Vinuesa lab has arrived at BlueSky! Follow us if you want to talk about all the exciting science going on in autoimmunity, genetics, and anything B cell-related 🧬 🧪
December 12, 2024 at 7:58 PM
Hi 👋🏼 The Vinuesa lab has arrived at BlueSky! Follow us if you want to talk about all the exciting science going on in autoimmunity, genetics, and anything B cell-related 🧬 🧪
Reposted by Roser TP
Having a color-blind colleague is a good reminder that we need to be more careful when designing figures for scientific publication 🧪
My lab has found this page especially useful for selecting color palettes, used in combination with different symbols: thenode.biologists.com/data-visuali...
My lab has found this page especially useful for selecting color palettes, used in combination with different symbols: thenode.biologists.com/data-visuali...
Color blind friendly palettes for data visualizations with categories
A discussion of color blind friendly palettes for labeling unique catergories in data visualization.
thenode.biologists.com
December 8, 2024 at 9:48 PM
Having a color-blind colleague is a good reminder that we need to be more careful when designing figures for scientific publication 🧪
My lab has found this page especially useful for selecting color palettes, used in combination with different symbols: thenode.biologists.com/data-visuali...
My lab has found this page especially useful for selecting color palettes, used in combination with different symbols: thenode.biologists.com/data-visuali...
Reposted by Roser TP
📌"Pas de gegant per entendre la causa de l' #autisme més comú"
📰 @ara.cat
✍️ @crisaez.bsky.social
➡️ shorturl.at/1Dztj
#IRBScience #Autism @xsalvatella1.bsky.social
📰 @ara.cat
✍️ @crisaez.bsky.social
➡️ shorturl.at/1Dztj
#IRBScience #Autism @xsalvatella1.bsky.social
December 5, 2024 at 8:53 AM
📌"Pas de gegant per entendre la causa de l' #autisme més comú"
📰 @ara.cat
✍️ @crisaez.bsky.social
➡️ shorturl.at/1Dztj
#IRBScience #Autism @xsalvatella1.bsky.social
📰 @ara.cat
✍️ @crisaez.bsky.social
➡️ shorturl.at/1Dztj
#IRBScience #Autism @xsalvatella1.bsky.social
Reposted by Roser TP
New PhD opportunity in the lab with @profjudiallen.bsky.social and @douglaspdyer.bsky.social looking at interactions between ILCs and the extracellular matrix. Application deadline Jan 10th 2025 - spread the word Bluesky immunologists!
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
(Bicentenary) ILC interactions with the extracellular matrix in inflamed barrier tissues at The University of Manchester on FindAPhD.com
PhD Project - (Bicentenary) ILC interactions with the extracellular matrix in inflamed barrier tissues at The University of Manchester, listed on FindAPhD.com
www.findaphd.com
November 28, 2024 at 3:06 PM
New PhD opportunity in the lab with @profjudiallen.bsky.social and @douglaspdyer.bsky.social looking at interactions between ILCs and the extracellular matrix. Application deadline Jan 10th 2025 - spread the word Bluesky immunologists!
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
Reposted by Roser TP
PhD opportunity in my lab together plus collaborative placement with Jenny Mjosberg's group at Karolinska. Looking for someone with a passion to learn and develop spatial 'omics pipelines in the gut. Deadline end of the week! Spread the word:
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...
(International Partnership Studentship) Defining an atlas of tissue-resident lymphocytes in the gut immune microenvironment at The University of Manchester on FindAPhD.com
PhD Project - (International Partnership Studentship) Defining an atlas of tissue-resident lymphocytes in the gut immune microenvironment at The University of Manchester, listed on FindAPhD.com
www.findaphd.com
November 25, 2024 at 11:16 AM
PhD opportunity in my lab together plus collaborative placement with Jenny Mjosberg's group at Karolinska. Looking for someone with a passion to learn and develop spatial 'omics pipelines in the gut. Deadline end of the week! Spread the word:
www.findaphd.com/phds/project...
www.findaphd.com/phds/project...