Journal of Experimental Medicine
@jem.org
Journal of Experimental Medicine publishes immunology, cancer, stem cells, microbial pathogenesis, vascular biology, and neurobiology research. Published by Rockefeller University Press @rupress.org
🌐 rupress.org/jem
🌐 rupress.org/jem
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Journal of Experimental Medicine
@jem.org
· Dec 17
The 2025 𝘉𝘦𝘴𝘵 𝘰𝘧 𝘑𝘌𝘔 highlights research in basic #immunology, #immunotherapy & #TumorImmunology, #InbornErrorsOfImmunity, #neurodegeneration, & #inflammation. We remain grounded in our commitment to publishing studies that push the boundaries of our knowledge forward 👉 rupress.org/jem/collecti...
Explore the 2025 𝘉𝘦𝘴𝘵 𝘰𝘧 𝘑𝘌𝘔 papers in basic #immunology, #immunotherapy and #TumorImmunology, #InbornErrorsOfImmunity, #neurodegeneration, and #inflammation 👉 rupress.org/jem/collecti...
THANK YOU to our authors, reviewers, and readers for your interest and continued support for JEM!
THANK YOU to our authors, reviewers, and readers for your interest and continued support for JEM!
January 16, 2026 at 2:31 PM
Explore the 2025 𝘉𝘦𝘴𝘵 𝘰𝘧 𝘑𝘌𝘔 papers in basic #immunology, #immunotherapy and #TumorImmunology, #InbornErrorsOfImmunity, #neurodegeneration, and #inflammation 👉 rupress.org/jem/collecti...
THANK YOU to our authors, reviewers, and readers for your interest and continued support for JEM!
THANK YOU to our authors, reviewers, and readers for your interest and continued support for JEM!
Reposted by Journal of Experimental Medicine
Welcome to @jem.org!
📢 JEM is delighted to introduce the 2026 Associate Editors: Semir Beyaz, Coco Chu, Erin M. Gibson (@erinmgibson.bsky.social), Benjamin G. Hale (@benhale.bsky.social), Guideng Li, Esther Obeng, João Pereira, and Pamela Rosato. Welcome! 👉 rupress.org/jem/pages/as...
January 15, 2026 at 9:36 PM
Welcome to @jem.org!
Join the #EMBL conference "The new cardiobiology: engineering, vascular, and molecular insights," 🗓️ February 16-19. Register for virtual attendance by February 9 👉 www.embl.org/about/info/c...
#EMBLCardioBiology
@events.embl.org
#EMBLCardioBiology
@events.embl.org
January 15, 2026 at 8:30 PM
Join the #EMBL conference "The new cardiobiology: engineering, vascular, and molecular insights," 🗓️ February 16-19. Register for virtual attendance by February 9 👉 www.embl.org/about/info/c...
#EMBLCardioBiology
@events.embl.org
#EMBLCardioBiology
@events.embl.org
Reposted by Journal of Experimental Medicine
Excited to join!
📢 JEM is delighted to introduce the 2026 Associate Editors: Semir Beyaz, Coco Chu, Erin M. Gibson (@erinmgibson.bsky.social), Benjamin G. Hale (@benhale.bsky.social), Guideng Li, Esther Obeng, João Pereira, and Pamela Rosato. Welcome! 👉 rupress.org/jem/pages/as...
January 15, 2026 at 4:04 PM
Excited to join!
Reposted by Journal of Experimental Medicine
Happy to join @jem.org as an Associate Editor for 2026 and to contribute to the journal’s publishing process and community!
📢 JEM is delighted to introduce the 2026 Associate Editors: Semir Beyaz, Coco Chu, Erin M. Gibson (@erinmgibson.bsky.social), Benjamin G. Hale (@benhale.bsky.social), Guideng Li, Esther Obeng, João Pereira, and Pamela Rosato. Welcome! 👉 rupress.org/jem/pages/as...
January 15, 2026 at 3:07 PM
Happy to join @jem.org as an Associate Editor for 2026 and to contribute to the journal’s publishing process and community!
🌐 Early registration deadline is approaching for @keystoneSymposia.bsky.social meeting, #Aging: #Immune Function & #OrganHealth, March 22-25 in Banff 🏔️
Register here 👉 www.keystonesymposia.org/conferences/...
#KSAging26
Register here 👉 www.keystonesymposia.org/conferences/...
#KSAging26
January 15, 2026 at 4:15 PM
🌐 Early registration deadline is approaching for @keystoneSymposia.bsky.social meeting, #Aging: #Immune Function & #OrganHealth, March 22-25 in Banff 🏔️
Register here 👉 www.keystonesymposia.org/conferences/...
#KSAging26
Register here 👉 www.keystonesymposia.org/conferences/...
#KSAging26
🌐 Early registration deadline is approaching for @keystoneSymposia.bsky.social meeting, #InnateImmunity: Diversity in #HostDefense & Disease, March 22-25 in Banff 🏔️
Register here 👉 www.keystonesymposia.org/conferences/...
#KSInnateImmune26
Register here 👉 www.keystonesymposia.org/conferences/...
#KSInnateImmune26
January 15, 2026 at 4:02 PM
🌐 Early registration deadline is approaching for @keystoneSymposia.bsky.social meeting, #InnateImmunity: Diversity in #HostDefense & Disease, March 22-25 in Banff 🏔️
Register here 👉 www.keystonesymposia.org/conferences/...
#KSInnateImmune26
Register here 👉 www.keystonesymposia.org/conferences/...
#KSInnateImmune26
Spatiotemporal dynamics of fetal liver hematopoietic niches. From Mesquita Peixoto, Soares-da-Silva, Bonnet, Zhou, Baroud, Pinto-do-Ó, Cumano, and colleagues 👉 rupress.org/jem/article/...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
January 15, 2026 at 3:15 PM
Spatiotemporal dynamics of fetal liver hematopoietic niches. From Mesquita Peixoto, Soares-da-Silva, Bonnet, Zhou, Baroud, Pinto-do-Ó, Cumano, and colleagues 👉 rupress.org/jem/article/...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📢 JEM is delighted to introduce the 2026 Associate Editors: Semir Beyaz, Coco Chu, Erin M. Gibson (@erinmgibson.bsky.social), Benjamin G. Hale (@benhale.bsky.social), Guideng Li, Esther Obeng, João Pereira, and Pamela Rosato. Welcome! 👉 rupress.org/jem/pages/as...
January 15, 2026 at 3:02 PM
📢 JEM is delighted to introduce the 2026 Associate Editors: Semir Beyaz, Coco Chu, Erin M. Gibson (@erinmgibson.bsky.social), Benjamin G. Hale (@benhale.bsky.social), Guideng Li, Esther Obeng, João Pereira, and Pamela Rosato. Welcome! 👉 rupress.org/jem/pages/as...
🌐 Explore emerging research w/ field leaders @keystoneSymposia.bsky.social #CancerImmunotherapy: Mechanisms, Clinical Advances & Combinations, March 15-18 in Québec 🏰 JEM's Senior Editor @montse-jexpmed.bsky.social is attending!
Register 👉 www.keystonesymposia.org/conferences/...
#KSCancerImmune26
Register 👉 www.keystonesymposia.org/conferences/...
#KSCancerImmune26
January 15, 2026 at 2:30 PM
🌐 Explore emerging research w/ field leaders @keystoneSymposia.bsky.social #CancerImmunotherapy: Mechanisms, Clinical Advances & Combinations, March 15-18 in Québec 🏰 JEM's Senior Editor @montse-jexpmed.bsky.social is attending!
Register 👉 www.keystonesymposia.org/conferences/...
#KSCancerImmune26
Register 👉 www.keystonesymposia.org/conferences/...
#KSCancerImmune26
Single-cell and spatial profiling highlights #TB-induced myofibroblasts as drivers of lung pathology. From Ian Mbano, Nuo Liu, Paul Elkington @unisouthampton.bsky.social, Alex Shalek @mit.edu, Alasdair Leslie (Africa Health Research Institute) et al: rupress.org/jem/article/...
#Tuberculosis
#Tuberculosis
January 14, 2026 at 8:30 PM
Single-cell and spatial profiling highlights #TB-induced myofibroblasts as drivers of lung pathology. From Ian Mbano, Nuo Liu, Paul Elkington @unisouthampton.bsky.social, Alex Shalek @mit.edu, Alasdair Leslie (Africa Health Research Institute) et al: rupress.org/jem/article/...
#Tuberculosis
#Tuberculosis
🌐 Explore emerging research with field leaders @keystoneSymposia.bsky.social #MyeloidCells : Heterogeneity & Therapeutic Promise, February 23-26 in Keystone🌲 JEM's Deputy Editor Gaia Trincucci @gaiajexpmed.bsky.social is attending! Register 👉 www.keystonesymposia.org/conferences/...
#KSMyeloid26
#KSMyeloid26
January 14, 2026 at 3:30 PM
🌐 Explore emerging research with field leaders @keystoneSymposia.bsky.social #MyeloidCells : Heterogeneity & Therapeutic Promise, February 23-26 in Keystone🌲 JEM's Deputy Editor Gaia Trincucci @gaiajexpmed.bsky.social is attending! Register 👉 www.keystonesymposia.org/conferences/...
#KSMyeloid26
#KSMyeloid26
Reposted by Journal of Experimental Medicine
It’s #JEM_Spotlight time again: this month we would like to highlight the detailed analysis of serological antibodies elicited after R21/Matrix-M malaria vaccine. Because, you know, vaccines work. doi.org/10.1084/jem.20241908
January 14, 2026 at 2:34 PM
It’s #JEM_Spotlight time again: this month we would like to highlight the detailed analysis of serological antibodies elicited after R21/Matrix-M malaria vaccine. Because, you know, vaccines work. doi.org/10.1084/jem.20241908
Amir Ferry, Ananda Goldrath et al. show that differentiation of tissue-resident memory T cells (TRM) is accompanied by the upregulation of the conventional DC1 (cDC1) chemoattractant, Xcl1. rupress.org/jem/article/...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
January 14, 2026 at 3:15 PM
Amir Ferry, Ananda Goldrath et al. show that differentiation of tissue-resident memory T cells (TRM) is accompanied by the upregulation of the conventional DC1 (cDC1) chemoattractant, Xcl1. rupress.org/jem/article/...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
🌐 Explore emerging #Hematopoiesis research with field leaders @keystoneSymposia.bsky.social, February 23-26 in Keystone🌲 JEM's Deputy Editor Gaia Trincucci @gaiajexpmed.bsky.social is attending! Register now 👉 www.keystonesymposia.org/conferences/...
#KSHemato26
#KSHemato26
January 14, 2026 at 3:15 PM
🌐 Explore emerging #Hematopoiesis research with field leaders @keystoneSymposia.bsky.social, February 23-26 in Keystone🌲 JEM's Deputy Editor Gaia Trincucci @gaiajexpmed.bsky.social is attending! Register now 👉 www.keystonesymposia.org/conferences/...
#KSHemato26
#KSHemato26
The cribriform plate: A dynamic central nervous system immune hub. New review from Collin J. Laaker, Zsuzsanna Fabry and colleagues @uwmadison.bsky.social: rupress.org/jem/article/...
#Neuroscience #Neuroinflammation
#Neuroscience #Neuroinflammation
January 13, 2026 at 3:45 PM
The cribriform plate: A dynamic central nervous system immune hub. New review from Collin J. Laaker, Zsuzsanna Fabry and colleagues @uwmadison.bsky.social: rupress.org/jem/article/...
#Neuroscience #Neuroinflammation
#Neuroscience #Neuroinflammation
Native stem cell transcriptional circuits define cardinal features of high-risk #leukemia. From Qing Wang, Francesco Boccalatte, Jason Xu, Iannis Aifantis, Mark Chiang and colleagues 👉 rupress.org/jem/article/...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
January 13, 2026 at 3:15 PM
Native stem cell transcriptional circuits define cardinal features of high-risk #leukemia. From Qing Wang, Francesco Boccalatte, Jason Xu, Iannis Aifantis, Mark Chiang and colleagues 👉 rupress.org/jem/article/...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📘 Part of 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
#Claudin 1-mediated positioning of DC1 to mTECs is essential for maintenance of central #tolerance. New study from Jiří Březina, Dominik Filipp and colleagues @imgprague.bsky.social @czechacademy.bsky.social: rupress.org/jem/article/...
#Autoimmunity #DendriticCells
#Autoimmunity #DendriticCells
January 13, 2026 at 2:45 PM
#Claudin 1-mediated positioning of DC1 to mTECs is essential for maintenance of central #tolerance. New study from Jiří Březina, Dominik Filipp and colleagues @imgprague.bsky.social @czechacademy.bsky.social: rupress.org/jem/article/...
#Autoimmunity #DendriticCells
#Autoimmunity #DendriticCells
Molecular and phenotypic blueprint of human #hematopoiesis links proliferation stress to #StemCell #aging. New study from Emanuele Lettera, Raffaella Di Micco @dimiccolab.bsky.social and colleagues: rupress.org/jem/article/...
#TechnicalAdvances #Resources #StemCells
#TechnicalAdvances #Resources #StemCells
January 13, 2026 at 2:30 PM
Molecular and phenotypic blueprint of human #hematopoiesis links proliferation stress to #StemCell #aging. New study from Emanuele Lettera, Raffaella Di Micco @dimiccolab.bsky.social and colleagues: rupress.org/jem/article/...
#TechnicalAdvances #Resources #StemCells
#TechnicalAdvances #Resources #StemCells
Transcription of #HIV-1 is heterogenous among authentic latent CD4+ T cell clones, say Cintia Bittar, Michel C. Nussenzweig @rockefeller.edu and colleagues: rupress.org/jem/article/...
#InfectiousDisease #HostDefense #Virology
#InfectiousDisease #HostDefense #Virology
January 12, 2026 at 4:31 PM
Transcription of #HIV-1 is heterogenous among authentic latent CD4+ T cell clones, say Cintia Bittar, Michel C. Nussenzweig @rockefeller.edu and colleagues: rupress.org/jem/article/...
#InfectiousDisease #HostDefense #Virology
#InfectiousDisease #HostDefense #Virology
ERAdP facilitates biogenesis of dense core vesicles in #Paneth cells to enhance intestinal defense, say Cunzhen Li, Zhen Xiong, Deyuan Kong, Yun Chen, Qiang Zhan, Zusen Fan (Institute of Biophysics, Chinese Academy of Sciences) and colleagues: rupress.org/jem/article/...
#InfectiousDisease #IBD
#InfectiousDisease #IBD
January 12, 2026 at 4:04 PM
ERAdP facilitates biogenesis of dense core vesicles in #Paneth cells to enhance intestinal defense, say Cunzhen Li, Zhen Xiong, Deyuan Kong, Yun Chen, Qiang Zhan, Zusen Fan (Institute of Biophysics, Chinese Academy of Sciences) and colleagues: rupress.org/jem/article/...
#InfectiousDisease #IBD
#InfectiousDisease #IBD
FOXO1 re-expression with a dual-recombinase allele rescues class switching in germinal center B cells, say Carlota Farré Díaz, Eleni Kabrani, Klaus Rajewsky and colleagues @mdc-berlin.bsky.social: rupress.org/jem/article/...
#LymphocyteBiology
#LymphocyteBiology
January 12, 2026 at 3:45 PM
FOXO1 re-expression with a dual-recombinase allele rescues class switching in germinal center B cells, say Carlota Farré Díaz, Eleni Kabrani, Klaus Rajewsky and colleagues @mdc-berlin.bsky.social: rupress.org/jem/article/...
#LymphocyteBiology
#LymphocyteBiology
Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes. From @hlpeks.bsky.social, @emmaschambers.bsky.social, @bcellsrosser.bsky.social, Ciurtin et al. 👉 rupress.org/jem/article/...
📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
January 12, 2026 at 3:15 PM
Estrogen influences class-switched memory B cell frequency only in humans with two X chromosomes. From @hlpeks.bsky.social, @emmaschambers.bsky.social, @bcellsrosser.bsky.social, Ciurtin et al. 👉 rupress.org/jem/article/...
📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
📘 In 2025: The Year in Experimental Medicine rupress.org/jem/collecti...
Tet2 deficiency–induced expansion of monocyte-derived #macrophages promotes liver #fibrosis Jiuxing Feng, Baitong Wu, Yujiang Geno Shi and colleagues (Fudan University): rupress.org/jem/article/...
#Hematopoiesis #InnateImmunity #Inflammation
#Hematopoiesis #InnateImmunity #Inflammation
January 12, 2026 at 3:03 PM
Tet2 deficiency–induced expansion of monocyte-derived #macrophages promotes liver #fibrosis Jiuxing Feng, Baitong Wu, Yujiang Geno Shi and colleagues (Fudan University): rupress.org/jem/article/...
#Hematopoiesis #InnateImmunity #Inflammation
#Hematopoiesis #InnateImmunity #Inflammation
T cell engagers emerge as a compelling therapeutic modality. New review from Baeuerle, Grieshaber-Bouyer, Sauer, and Michaelson: rupress.org/jem/article/...
#CancerFocus #TumorImmunology #TcellEngagers
#CancerFocus #TumorImmunology #TcellEngagers
January 12, 2026 at 2:30 PM
T cell engagers emerge as a compelling therapeutic modality. New review from Baeuerle, Grieshaber-Bouyer, Sauer, and Michaelson: rupress.org/jem/article/...
#CancerFocus #TumorImmunology #TcellEngagers
#CancerFocus #TumorImmunology #TcellEngagers