Mae Woods
@maewoods.bsky.social
Passionate about compbio | high performance computing | mathematics | digitalization | cell & gene therapy. Opinions are my own.
GitHub: https://github.com/MaeWoods
GitHub: https://github.com/MaeWoods
Reposted by Mae Woods
So what is a #Supermoon? Well, the Moon is typically ~¼ million miles away (30 Earths in a row), but thanks to its elliptical orbit, that distance changes. Tonight the Full Moon is 2-Earths closer than normal (221,823 miles away), making it appear ~15% brighter than usual hence #Supermoon! 🔭🧪
If you've got clear skies, go outside and wave at our neighbour who is looking particularly stunning tonight. And if you have them, root out the binoculars to get a closer look at the grey maria: ~3.5 billion years ago these were seas of molten lava 🤓 #supermoon 🔭🧪
November 5, 2025 at 4:04 PM
So what is a #Supermoon? Well, the Moon is typically ~¼ million miles away (30 Earths in a row), but thanks to its elliptical orbit, that distance changes. Tonight the Full Moon is 2-Earths closer than normal (221,823 miles away), making it appear ~15% brighter than usual hence #Supermoon! 🔭🧪
Reposted by Mae Woods
There's a PhD position now available with me in Bath, on the evolution of symbiosis. www.findaphd.com/phds/project.... The supervisory team also includes @anja1.bsky.social @phil-donoghue.bsky.social and others. NB, this is open both to UK-based students *and* to international students :)
The genomic basis of symbiotic integration at University of Bath on FindAPhD.com
PhD Project - The genomic basis of symbiotic integration at University of Bath, listed on FindAPhD.com
www.findaphd.com
October 9, 2025 at 9:39 AM
There's a PhD position now available with me in Bath, on the evolution of symbiosis. www.findaphd.com/phds/project.... The supervisory team also includes @anja1.bsky.social @phil-donoghue.bsky.social and others. NB, this is open both to UK-based students *and* to international students :)
Reposted by Mae Woods
#compchem #compbio Happy to be part of this new paper just published in @commsbio.nature.com : "Targeting RNA with Small Molecules using State-of-the-Art Methods Provides Highly Predictive Affinities of Riboswitch Inhibitors."
www.nature.com/articles/s42...
@qubit-pharma.bsky.social
www.nature.com/articles/s42...
@qubit-pharma.bsky.social
October 1, 2025 at 1:15 PM
#compchem #compbio Happy to be part of this new paper just published in @commsbio.nature.com : "Targeting RNA with Small Molecules using State-of-the-Art Methods Provides Highly Predictive Affinities of Riboswitch Inhibitors."
www.nature.com/articles/s42...
@qubit-pharma.bsky.social
www.nature.com/articles/s42...
@qubit-pharma.bsky.social
Reposted by Mae Woods
Calling early-career developmental biologists!
Apply for a funded place at our #Workshop, Novelty, Co-option and Divergence During Gene Network Evolution.
Application deadline: 5 December
www.biologists.com/workshops/ju...
#DevBio #BiologistsWorkshops #Collaboration #Networking
Apply for a funded place at our #Workshop, Novelty, Co-option and Divergence During Gene Network Evolution.
Application deadline: 5 December
www.biologists.com/workshops/ju...
#DevBio #BiologistsWorkshops #Collaboration #Networking
September 28, 2025 at 1:19 PM
Calling early-career developmental biologists!
Apply for a funded place at our #Workshop, Novelty, Co-option and Divergence During Gene Network Evolution.
Application deadline: 5 December
www.biologists.com/workshops/ju...
#DevBio #BiologistsWorkshops #Collaboration #Networking
Apply for a funded place at our #Workshop, Novelty, Co-option and Divergence During Gene Network Evolution.
Application deadline: 5 December
www.biologists.com/workshops/ju...
#DevBio #BiologistsWorkshops #Collaboration #Networking
Reposted by Mae Woods
Why am I doing this? Simon Sinek says that all good stories start with "Why" so... I had a go at starting with "Why", and it changed the way I think about #fairness and #progress.
#PersonalDevelopment #SelfHelp #Values #Ethics #WellBeing #Humanity #Collective #Individual #nonzero
#PersonalDevelopment #SelfHelp #Values #Ethics #WellBeing #Humanity #Collective #Individual #nonzero
FAIRNESS & PROGRESS
Exploring the relationship between fairness and progress, emphasizing non-zero-sum games as a means to enhance human well-being and collective growth.
nonzerosum.games
September 27, 2025 at 8:17 AM
Why am I doing this? Simon Sinek says that all good stories start with "Why" so... I had a go at starting with "Why", and it changed the way I think about #fairness and #progress.
#PersonalDevelopment #SelfHelp #Values #Ethics #WellBeing #Humanity #Collective #Individual #nonzero
#PersonalDevelopment #SelfHelp #Values #Ethics #WellBeing #Humanity #Collective #Individual #nonzero
Reposted by Mae Woods
Reposted by Mae Woods
A new paper I worked on is out in Justice Quarterly! I won't speak on the substantive nature of the paper as I worked solely as the methodologist, but I developed a new matching method not otherwise described in the literature, and I want to tell you about it!
#statssky #casualsky
#statssky #casualsky
The Effects of a Place-Based Intervention on Resident Reporting of Crime and Service Needs: A Frontier Matching Approach
Prior research has found that reporting of crime incidents and service needs remain low in many U.S. cities. This study employs a matching strategy using observational data from a large public repo...
doi.org
September 18, 2025 at 3:23 PM
A new paper I worked on is out in Justice Quarterly! I won't speak on the substantive nature of the paper as I worked solely as the methodologist, but I developed a new matching method not otherwise described in the literature, and I want to tell you about it!
#statssky #casualsky
#statssky #casualsky
Reposted by Mae Woods
Pleasure to present the final project of my PhD research at #ConformationalDesign25!
Thank you to AstraZeneca for hosting and the organising committee for a day of engaging talks 👏
#CompChem #ChemSky
Thank you to AstraZeneca for hosting and the organising committee for a day of engaging talks 👏
#CompChem #ChemSky
March 21, 2025 at 11:26 AM
Pleasure to present the final project of my PhD research at #ConformationalDesign25!
Thank you to AstraZeneca for hosting and the organising committee for a day of engaging talks 👏
#CompChem #ChemSky
Thank you to AstraZeneca for hosting and the organising committee for a day of engaging talks 👏
#CompChem #ChemSky
Reposted by Mae Woods
In 1950, Alan Turing - while at @manchester.ac.uk - proposed a simple but profound experiment: can a machine convincingly imitate human thought?
We now call it the Turing Test. 🧠💻
We now call it the Turing Test. 🧠💻
a man wearing suspenders and a watch looks down in front of a machine
Alt: Alarn Turing looks down in front of a machine
media.tenor.com
September 16, 2025 at 12:33 PM
In 1950, Alan Turing - while at @manchester.ac.uk - proposed a simple but profound experiment: can a machine convincingly imitate human thought?
We now call it the Turing Test. 🧠💻
We now call it the Turing Test. 🧠💻
AAV related news. Restored enzyme activity in the brain www.insideprecisionmedicine.com/topics/preci...
Gene Therapy Can Restore Myelin in Children with Fatal Brain Disorder
MYR-101 gene therapy reduces N-acetylaspartate, increases myelin, and improves development in Canavan disease patients.
www.insideprecisionmedicine.com
September 21, 2025 at 6:15 AM
AAV related news. Restored enzyme activity in the brain www.insideprecisionmedicine.com/topics/preci...
Reposted by Mae Woods
Excited to be a topic editor for:
Synthetic Biology in Pharmacology: Engineering Circuits and Cells for Therapeutics
We are seeking articles regarding:
- Artificial Cells for Drug Delivery
- Metabolic Engineering for Drug Production
- Synthetic Gene Circuits
tinyurl.com/38j4d6u4
🧪👩🔬#Chemsky
Synthetic Biology in Pharmacology: Engineering Circuits and Cells for Therapeutics
We are seeking articles regarding:
- Artificial Cells for Drug Delivery
- Metabolic Engineering for Drug Production
- Synthetic Gene Circuits
tinyurl.com/38j4d6u4
🧪👩🔬#Chemsky
Frontiers | Synthetic Biology in Pharmacology: Engineering Circuits and Cells for Therapeutics
Synthetic biology, an interdisciplinary field blending principles from molecular biology, organic chemistry, computational modeling, and nanobiotechnology, f...
www.frontiersin.org
September 12, 2025 at 11:08 PM
Excited to be a topic editor for:
Synthetic Biology in Pharmacology: Engineering Circuits and Cells for Therapeutics
We are seeking articles regarding:
- Artificial Cells for Drug Delivery
- Metabolic Engineering for Drug Production
- Synthetic Gene Circuits
tinyurl.com/38j4d6u4
🧪👩🔬#Chemsky
Synthetic Biology in Pharmacology: Engineering Circuits and Cells for Therapeutics
We are seeking articles regarding:
- Artificial Cells for Drug Delivery
- Metabolic Engineering for Drug Production
- Synthetic Gene Circuits
tinyurl.com/38j4d6u4
🧪👩🔬#Chemsky
Reposted by Mae Woods
This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation www.sciencedirect.com/science/arti...
Highlight: α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation www.sciencedirect.com/science/arti...
bims-proteo 2025-09-14 papers
biomed.news
September 14, 2025 at 7:09 AM
This week's selection of articles on #proteostasis thanks to @biomednews.bsky.social -- biomed.news/bims-proteo/...
Highlight: α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation www.sciencedirect.com/science/arti...
Highlight: α-Synuclein aggregates inhibit ESCRT-III through sequestration and collateral degradation www.sciencedirect.com/science/arti...
Reposted by Mae Woods
On this week, 40 years ago, my friend Ralph Isberg, then a postdoc with Stan Falkow, reported the discovery of the 1st invasin gene in @nature.com "We report here the identification of a single genetic locus from this organism (Y. pseudotuberculosis) that is sufficient to convert the innocuous
September 13, 2025 at 1:08 PM
On this week, 40 years ago, my friend Ralph Isberg, then a postdoc with Stan Falkow, reported the discovery of the 1st invasin gene in @nature.com "We report here the identification of a single genetic locus from this organism (Y. pseudotuberculosis) that is sufficient to convert the innocuous
I found this article for some light weekend reading. Healthcare premises cost guides - outdated but interesting nonetheless
www.england.nhs.uk/wp-content/u...
Next time when buying a flag (~£5) Why not recycle cardboard, make your own & donate the cost?
nhscharitiestogether.co.uk?utm_source=g...
www.england.nhs.uk/wp-content/u...
Next time when buying a flag (~£5) Why not recycle cardboard, make your own & donate the cost?
nhscharitiestogether.co.uk?utm_source=g...
NHS Charities Together
NHS Charities Together is the national charity caring for the NHS. Help us make healthcare better for everyone.
nhscharitiestogether.co.uk
September 14, 2025 at 10:12 AM
I found this article for some light weekend reading. Healthcare premises cost guides - outdated but interesting nonetheless
www.england.nhs.uk/wp-content/u...
Next time when buying a flag (~£5) Why not recycle cardboard, make your own & donate the cost?
nhscharitiestogether.co.uk?utm_source=g...
www.england.nhs.uk/wp-content/u...
Next time when buying a flag (~£5) Why not recycle cardboard, make your own & donate the cost?
nhscharitiestogether.co.uk?utm_source=g...
Reposted by Mae Woods
In a new work with Joseph Rich and Conrad Oakes we tackle the problem of how to best organize alluvial plots. We formalize two optimization problems and develop a solution for them based on the neighbornet algorithm, implemented in the program wompwomp: github.com/pachterlab/w...
September 5, 2025 at 12:20 PM
In a new work with Joseph Rich and Conrad Oakes we tackle the problem of how to best organize alluvial plots. We formalize two optimization problems and develop a solution for them based on the neighbornet algorithm, implemented in the program wompwomp: github.com/pachterlab/w...
Reposted by Mae Woods
scVerse conference is at Stanford this year! Encourage folks (especially Bay Area/West coast folks) to sign up and attend. Cool workshops/talks and other events + great community of developers for one of the most widely used open source software for single cell data analysis!
🎉 scverse conference 2025 Registration & Call for Abstracts NOW OPEN! 🎉
We're excited to announce that registration and the call for abstracts are officially open for the scverse Conference 2025!
Details in thread!
🧵 1/3
We're excited to announce that registration and the call for abstracts are officially open for the scverse Conference 2025!
Details in thread!
🧵 1/3
August 26, 2025 at 6:50 PM
scVerse conference is at Stanford this year! Encourage folks (especially Bay Area/West coast folks) to sign up and attend. Cool workshops/talks and other events + great community of developers for one of the most widely used open source software for single cell data analysis!
Reposted by Mae Woods
We are excited to host Drs. Amit Sharma and Xiaoyan Xu for our upcoming #GDTcellclub virtual talks.
Date: August 21, 2025
Time: 12pm (New York) | 5pm (London, UK)
nyulangone.zoom.us/j/9589051706...
*Talks will be recorded* for those who are unable to attend live.
Date: August 21, 2025
Time: 12pm (New York) | 5pm (London, UK)
nyulangone.zoom.us/j/9589051706...
*Talks will be recorded* for those who are unable to attend live.
August 16, 2025 at 4:29 PM
We are excited to host Drs. Amit Sharma and Xiaoyan Xu for our upcoming #GDTcellclub virtual talks.
Date: August 21, 2025
Time: 12pm (New York) | 5pm (London, UK)
nyulangone.zoom.us/j/9589051706...
*Talks will be recorded* for those who are unable to attend live.
Date: August 21, 2025
Time: 12pm (New York) | 5pm (London, UK)
nyulangone.zoom.us/j/9589051706...
*Talks will be recorded* for those who are unable to attend live.
Reposted by Mae Woods
A UN survey found that 67% of people believe in a better future with 15 to 17 year-olds being the most optimistic. To achieve this, we share ways that educators can bring #accessibility skills into lessons to help build an inclusive digital world for future generations.
#InternationalYouthDay #A11y
#InternationalYouthDay #A11y
August 12, 2025 at 7:55 AM
A UN survey found that 67% of people believe in a better future with 15 to 17 year-olds being the most optimistic. To achieve this, we share ways that educators can bring #accessibility skills into lessons to help build an inclusive digital world for future generations.
#InternationalYouthDay #A11y
#InternationalYouthDay #A11y
Reposted by Mae Woods
Happy @diffuseproject.bsky.social launch day! Check out our latest effort. We're grappling with how to better understand protein dynamics and capture/share the information that would best allow the community to make use of that data. Take a look!
What’s the next PDB? Maybe it’s …the PDB.
We just launched @diffuseproject.bsky.social a structural biology initiative exploring protein motion & rethinking how we generate and use experimental data. Quick 🧵👇
www.diffuse.science
We just launched @diffuseproject.bsky.social a structural biology initiative exploring protein motion & rethinking how we generate and use experimental data. Quick 🧵👇
www.diffuse.science
The Diffuse Project
The Diffuse Project
www.diffuse.science
August 12, 2025 at 4:48 PM
Happy @diffuseproject.bsky.social launch day! Check out our latest effort. We're grappling with how to better understand protein dynamics and capture/share the information that would best allow the community to make use of that data. Take a look!
Reposted by Mae Woods
Happy to announce our paper comparing embryonic gene expression between C. elegans and C. briggsae, work led by Christopher Large with Rupa Khanal and in collaboration with Junhyong Kim and Bob Waterston. www.science.org/doi/10.1126/...
Lineage-resolved analysis of embryonic gene expression evolution in C. elegans and C. briggsae
The constraints that govern the evolution of gene expression patterns across development remain unclear. Single-cell RNA sequencing can detail these constraints by systematically profiling homologous ...
www.science.org
June 20, 2025 at 8:25 PM
Happy to announce our paper comparing embryonic gene expression between C. elegans and C. briggsae, work led by Christopher Large with Rupa Khanal and in collaboration with Junhyong Kim and Bob Waterston. www.science.org/doi/10.1126/...
Reposted by Mae Woods
Which RNAs are functional? Been a long time goal of @deboramarks.bsky.social to start an RNA sequence —> function and structure mapping.
Huge thx to team for pushing on this when - led by Rohit Arora and Murphy Angelo for seeing this thru and Pascal Notin for pulling together!!!
Huge thx to team for pushing on this when - led by Rohit Arora and Murphy Angelo for seeing this thru and Pascal Notin for pulling together!!!
🚨 New paper 🚨 RNA modeling just got its own Gym! 🏋️ Introducing RNAGym, large-scale benchmarks for RNA fitness and structure prediction.
🧵 1/9
🧵 1/9
June 18, 2025 at 7:47 PM
Which RNAs are functional? Been a long time goal of @deboramarks.bsky.social to start an RNA sequence —> function and structure mapping.
Huge thx to team for pushing on this when - led by Rohit Arora and Murphy Angelo for seeing this thru and Pascal Notin for pulling together!!!
Huge thx to team for pushing on this when - led by Rohit Arora and Murphy Angelo for seeing this thru and Pascal Notin for pulling together!!!
