Leonardo Claudino
@lmbclaudino.bsky.social
Computer Science PhD. Staff Scientist at the Laboratory of Brain and Cognition (LBC) @NIMH/NIH. Opinions are my own.
Reposted by Leonardo Claudino
This is a nice paper. It faces down a common problem: in order to explain to why a common approach cannot work even in theory, we first need to teach a framework in which regression is not magic that tells us which variables on right cause the variable on left. It's exhausting.
Anyway great paper!
Anyway great paper!
October 7, 2025 at 11:38 AM
This is a nice paper. It faces down a common problem: in order to explain to why a common approach cannot work even in theory, we first need to teach a framework in which regression is not magic that tells us which variables on right cause the variable on left. It's exhausting.
Anyway great paper!
Anyway great paper!
Reposted by Leonardo Claudino
Mirror manifolds: partially overlapping neural subspaces for speaking and listening https://www.biorxiv.org/content/10.1101/2025.09.20.677504v1
September 20, 2025 at 11:15 PM
Mirror manifolds: partially overlapping neural subspaces for speaking and listening https://www.biorxiv.org/content/10.1101/2025.09.20.677504v1
Reposted by Leonardo Claudino
In retrospect, it was the presidency of Obrack Ofuane -- a Greek ambulance-chasing lawyer from Queens with eye-popping white veneers -- from 2009 to 1017 that set us on this current course toward madness
I've seen this on Bluesky and had to try it myself. The image below was the response to the prompt: "Show me a diagram of the US presidents since Herbert Hoover, with their names and years in office under their photos" Bravo, OpenAI, bravo.
August 8, 2025 at 7:21 PM
In retrospect, it was the presidency of Obrack Ofuane -- a Greek ambulance-chasing lawyer from Queens with eye-popping white veneers -- from 2009 to 1017 that set us on this current course toward madness
Reposted by Leonardo Claudino
Repetition-related reductions in neural activity support improved behavior through increases in oscillatory power https://www.biorxiv.org/content/10.1101/2025.07.06.663291v1
July 7, 2025 at 3:17 AM
Repetition-related reductions in neural activity support improved behavior through increases in oscillatory power https://www.biorxiv.org/content/10.1101/2025.07.06.663291v1
Reposted by Leonardo Claudino
New work from our lab investigating the relationship between repetition suppression, repetition priming and increases in oscillatory power in simultaneous fMRI-EEG. Induced power increases are strongly associated with priming magnitude, supporting a mix of the synchrony and facilitation models.
Repetition-related reductions in neural activity support improved behavior through increases in oscillatory power https://www.biorxiv.org/content/10.1101/2025.07.06.663291v1
July 7, 2025 at 2:30 PM
New work from our lab investigating the relationship between repetition suppression, repetition priming and increases in oscillatory power in simultaneous fMRI-EEG. Induced power increases are strongly associated with priming magnitude, supporting a mix of the synchrony and facilitation models.
Reposted by Leonardo Claudino
Escherichia coli bacteria (E. coli) can convert a molecule derived from a waste plastic bottle into paracetamol, a pain medication also known as acetaminophen, according to a paper in Nature Chemistry. go.nature.com/44cvLw1 #chemsky 🧪
July 6, 2025 at 1:16 AM
Escherichia coli bacteria (E. coli) can convert a molecule derived from a waste plastic bottle into paracetamol, a pain medication also known as acetaminophen, according to a paper in Nature Chemistry. go.nature.com/44cvLw1 #chemsky 🧪
Reposted by Leonardo Claudino
![Wikipedia definition of "idiot plot": In literary criticism, an idiot plot is one which is "kept in motion solely by virtue of the fact that everybody involved is an idiot",[1]: 26 and where the story would quickly end, or possibly not even happen, if this were not the case.](https://cdn.bsky.app/img/feed_thumbnail/plain/did:plc:6waxgers6k753hgsmh2prmv7/bafkreicwreql25fxq3hliczfe3pgz6djdjbrvwbax2d2oyevjm73tb3voy@jpeg)
Reposted by Leonardo Claudino
Preprint alert 🚨! Excited to share our new work on metacognition in value-based decision-making. www.biorxiv.org/cgi/content/.... We ask whether it is possible to derive a computational measure of metacognitive ability for economic preference choices.
Computational characterization of metacognitive ability in subjective decision-making
Metacognition is the process of reflecting on and controlling one's own thoughts and behaviors. Metacognitive ability is often measured through modeling the relationship between confidence reports and...
www.biorxiv.org
May 29, 2025 at 2:42 AM
Preprint alert 🚨! Excited to share our new work on metacognition in value-based decision-making. www.biorxiv.org/cgi/content/.... We ask whether it is possible to derive a computational measure of metacognitive ability for economic preference choices.
Reposted by Leonardo Claudino
This project began after my move to NIH and has been an eye-opening synthesis of my and Silvia's previous work. Couldn't be prouder of the incredible work of my first trainee and first author Corey Plate, who has just left NIH to begin his MD/PhD!
Preprint alert 🚨! Excited to share our new work on metacognition in value-based decision-making. www.biorxiv.org/cgi/content/.... We ask whether it is possible to derive a computational measure of metacognitive ability for economic preference choices.
Computational characterization of metacognitive ability in subjective decision-making
Metacognition is the process of reflecting on and controlling one's own thoughts and behaviors. Metacognitive ability is often measured through modeling the relationship between confidence reports and...
www.biorxiv.org
May 29, 2025 at 3:10 AM
This project began after my move to NIH and has been an eye-opening synthesis of my and Silvia's previous work. Couldn't be prouder of the incredible work of my first trainee and first author Corey Plate, who has just left NIH to begin his MD/PhD!
Reposted by Leonardo Claudino
Here’s your chance to ask the new NIH director some questions. Don’t be shy!
NIH is going to hold a town hall for staff with director Jayanta Bhattacharya, and apparently the form to submit questions is publicly available. In case that’s of interest.
forms.office.com/pages/respon...
forms.office.com/pages/respon...
April 25, 2025 at 2:58 AM
Here’s your chance to ask the new NIH director some questions. Don’t be shy!
Reposted by Leonardo Claudino
I’ll just leave this here.
April 6, 2025 at 3:23 PM
I’ll just leave this here.
Reposted by Leonardo Claudino
A majority of a panel of justices of Brazil’s Supreme Court has accepted charges against former President Jair Bolsonaro over an alleged attempt to stay in office after his 2022 election defeat.
Majority of Brazil's Supreme Court panel accepts coup charge against ex-President Bolsonaro
A majority of a panel of justices of Brazil’s Supreme Court has accepted charges against former President Jair Bolsonaro over an alleged attempt to stay in office after his 2022 election defeat.
bit.ly
March 26, 2025 at 3:39 PM
A majority of a panel of justices of Brazil’s Supreme Court has accepted charges against former President Jair Bolsonaro over an alleged attempt to stay in office after his 2022 election defeat.
Reposted by Leonardo Claudino
Interested in dopamine? Have fMRI data? We’ve identified a temporal BOLD feature that carries rich information about dopamine physiology. This measure, obtainable from resting-state and task fMRI, opens new ways to indirectly probe dopamine’s role in cognition and disease. 1/n tinyurl.com/bddyz67b
Temporal fMRI Dynamics Map Dopamine Physiology
Spatial variations in dopamine function are linked to cognition and substance use disorders but are challenging to characterize with current methods. Because dopamine influences blood vessel dilation,...
www.biorxiv.org
March 26, 2025 at 12:40 PM
Interested in dopamine? Have fMRI data? We’ve identified a temporal BOLD feature that carries rich information about dopamine physiology. This measure, obtainable from resting-state and task fMRI, opens new ways to indirectly probe dopamine’s role in cognition and disease. 1/n tinyurl.com/bddyz67b
Reposted by Leonardo Claudino
We still have space for a few more folks to attend. All expenses paid!
We're hosting a hackathon in May! This is aimed at jsPsych users who want to learn how to contribute to open source software and extend jsPsych. It's free, and we'll cover travel expenses. Learn more and sign up here:
jspsych.github.io/hackathon/sp...
jspsych.github.io/hackathon/sp...
jsPsych Spring 2025
jspsych.github.io
March 26, 2025 at 1:37 PM
We still have space for a few more folks to attend. All expenses paid!
Reposted by Leonardo Claudino
This cure for sickle cell anemia was made possible by NIH-funded research to turn the gene for fetal hemoglobin back on. It was done predominantly by NIH researchers, including intramural researchers on the NIH campus.
irp.nih.gov/catalyst/33/...
irp.nih.gov/catalyst/33/...
March 15, 2025 at 6:44 PM
This cure for sickle cell anemia was made possible by NIH-funded research to turn the gene for fetal hemoglobin back on. It was done predominantly by NIH researchers, including intramural researchers on the NIH campus.
irp.nih.gov/catalyst/33/...
irp.nih.gov/catalyst/33/...
Reposted by Leonardo Claudino
as I tell my Genetics class every year, this breakthrough is based on 70 years of NIH-funded, basic research, commercialized by biotech
bsky.app/profile/need...
bsky.app/profile/need...
March 15, 2025 at 6:49 PM
as I tell my Genetics class every year, this breakthrough is based on 70 years of NIH-funded, basic research, commercialized by biotech
bsky.app/profile/need...
bsky.app/profile/need...
Reposted by Leonardo Claudino
People who consumed 200 to 300 milligrams of caffeine a day were less likely to develop coronary heart disease, Type 2 diabetes or stroke.
Drinking this much coffee a day is linked to a lower risk of several diseases
People who consumed 200 to 300 milligrams of caffeine a day were less likely to develop coronary heart disease, Type 2 diabetes or stroke.
nbcnews.to
March 11, 2025 at 12:00 PM
People who consumed 200 to 300 milligrams of caffeine a day were less likely to develop coronary heart disease, Type 2 diabetes or stroke.
Reposted by Leonardo Claudino
Can we use brain scans to identify biologically distinct "autisms"? And If so, how?
In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions!
Find out more here 👇👇
www.biorxiv.org/content/10.1...
Thread below 🧵 1/n
In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions!
Find out more here 👇👇
www.biorxiv.org/content/10.1...
Thread below 🧵 1/n
March 6, 2025 at 11:18 AM
Can we use brain scans to identify biologically distinct "autisms"? And If so, how?
In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions!
Find out more here 👇👇
www.biorxiv.org/content/10.1...
Thread below 🧵 1/n
In our latest cross-species study 🐭👨 with @iitalk.bsky.social we dive into these questions!
Find out more here 👇👇
www.biorxiv.org/content/10.1...
Thread below 🧵 1/n
“Waste, abuse and fraud” is the new bs talking point to be repeated over and over without any evidence by the red hat folks
March 6, 2025 at 6:49 PM
“Waste, abuse and fraud” is the new bs talking point to be repeated over and over without any evidence by the red hat folks
Reposted by Leonardo Claudino
“I’m Still Here” wins Best International Feature Film at the #Oscars. It will also be up for Best Picture at the end of the night, and its star, Fernanda Torres, remains a dark horse in the Best Actress category. www.newyorker.com/live/oscars-...
March 3, 2025 at 3:13 AM
“I’m Still Here” wins Best International Feature Film at the #Oscars. It will also be up for Best Picture at the end of the night, and its star, Fernanda Torres, remains a dark horse in the Best Actress category. www.newyorker.com/live/oscars-...
Reposted by Leonardo Claudino
I currently have two fully-funded PhD opportunities in my lab - both providing a chance to work on the incredible LEAF data set that we have been collecting the last couple of years (220 children followed longitudinally from 10-30 months on measures of attention and early EF). Please share!
March 1, 2025 at 1:02 PM
I currently have two fully-funded PhD opportunities in my lab - both providing a chance to work on the incredible LEAF data set that we have been collecting the last couple of years (220 children followed longitudinally from 10-30 months on measures of attention and early EF). Please share!
Reposted by Leonardo Claudino
This new Atlantic piece on the timeline of the NIH shutdown reads like the script to a new Soderbergh film. It is so, so dark and perfectly captures the evil and intentional chaos behind everything we've experienced over the last month www.theatlantic.com/health/archi...
Inside the Collapse at the NIH
Administration officials pressured the NIH to avoid clear advice from the agency’s own lawyers to restart grant funding now.
www.theatlantic.com
February 27, 2025 at 7:12 PM
This new Atlantic piece on the timeline of the NIH shutdown reads like the script to a new Soderbergh film. It is so, so dark and perfectly captures the evil and intentional chaos behind everything we've experienced over the last month www.theatlantic.com/health/archi...
Reposted by Leonardo Claudino
One of the most-viewed PNAS articles in the last week is “Neural network retuning and neural predictors of learning success associated with cello training.” Explore the article here: www.pnas.org/doi/10.1073/...
For more trending articles, visit ow.ly/Me2U50SkLRZ.
For more trending articles, visit ow.ly/Me2U50SkLRZ.
February 27, 2025 at 6:18 PM
One of the most-viewed PNAS articles in the last week is “Neural network retuning and neural predictors of learning success associated with cello training.” Explore the article here: www.pnas.org/doi/10.1073/...
For more trending articles, visit ow.ly/Me2U50SkLRZ.
For more trending articles, visit ow.ly/Me2U50SkLRZ.
Reposted by Leonardo Claudino
www.nature.com/articles/s41... awesome new work out today! From the Lee lab in the intramural research program at NIMH!
Brain-wide presynaptic networks of functionally distinct cortical neurons - Nature
Behavioural-state-dependent pyramidal neurons have a distinct pattern of long-range glutamatergic inputs, with a larger proportion of thalamic versus motor cortex inputs compared with non-behavio...
www.nature.com
February 27, 2025 at 12:21 AM
www.nature.com/articles/s41... awesome new work out today! From the Lee lab in the intramural research program at NIMH!
Reposted by Leonardo Claudino
📢 We’re hiring!
Join the Somneuro team at UMass Amherst! Work with cutting-edge developmental cognitive neuroscience research and gain hands-on experience in sleep physiology!
🚀 Post- baccalaureate
📆 Apply now!
#CognitiveNeuroscience #ResearchJobs #PsychologyJobs #Academia
Join the Somneuro team at UMass Amherst! Work with cutting-edge developmental cognitive neuroscience research and gain hands-on experience in sleep physiology!
🚀 Post- baccalaureate
📆 Apply now!
#CognitiveNeuroscience #ResearchJobs #PsychologyJobs #Academia
Details - Research Fellow - Somneuro Lab | Human Resources | UMass Amherst
careers.umass.edu
February 23, 2025 at 11:49 PM
📢 We’re hiring!
Join the Somneuro team at UMass Amherst! Work with cutting-edge developmental cognitive neuroscience research and gain hands-on experience in sleep physiology!
🚀 Post- baccalaureate
📆 Apply now!
#CognitiveNeuroscience #ResearchJobs #PsychologyJobs #Academia
Join the Somneuro team at UMass Amherst! Work with cutting-edge developmental cognitive neuroscience research and gain hands-on experience in sleep physiology!
🚀 Post- baccalaureate
📆 Apply now!
#CognitiveNeuroscience #ResearchJobs #PsychologyJobs #Academia