Graham Murray
@gkmurray.bsky.social
Professor of Psychiatry and Neuroscience at Cambridge University and Cambridgeshire and Peterborough NHS Trust. Interested in early intervention and personalised medicine.
Reposted by Graham Murray
this is one of my favourite observations about sample size calculations. (afaik first articulated by Miettinen in 1985)
November 25, 2025 at 10:56 AM
this is one of my favourite observations about sample size calculations. (afaik first articulated by Miettinen in 1985)
Reposted by Graham Murray
This chart (which applies even more to social media than it did to TV) lives in my head rent free.
Social media enveloping traditional media means everything and everyone is now competing in the entertainment market. Boring stuff like policy that affects millions of lives doesn’t stand a chance.
Social media enveloping traditional media means everything and everyone is now competing in the entertainment market. Boring stuff like policy that affects millions of lives doesn’t stand a chance.
November 23, 2025 at 8:24 PM
This chart (which applies even more to social media than it did to TV) lives in my head rent free.
Social media enveloping traditional media means everything and everyone is now competing in the entertainment market. Boring stuff like policy that affects millions of lives doesn’t stand a chance.
Social media enveloping traditional media means everything and everyone is now competing in the entertainment market. Boring stuff like policy that affects millions of lives doesn’t stand a chance.
Reposted by Graham Murray
📣🔥Thrilled to announce that 2026 Computational Psychiatry Conference will take place in New Haven, CT, btw July 14-16 -
www.cpconf.org
@robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop
More info to come soon!
www.cpconf.org
@robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop
More info to come soon!
November 21, 2025 at 7:27 PM
📣🔥Thrilled to announce that 2026 Computational Psychiatry Conference will take place in New Haven, CT, btw July 14-16 -
www.cpconf.org
@robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop
More info to come soon!
www.cpconf.org
@robbrutledge.bsky.social @drrickadams.bsky.social @tobiasuhauser.bsky.social @docqhuys.bsky.social @clairegillan.bsky.social Sonia Bishop
More info to come soon!
Reposted by Graham Murray
Individuals with schizophrenia exhibit region-specific reductions in dendritic spine densities across cortical regions involved in visual-spatial working memory. ja.ma/48dYiTW
November 21, 2025 at 12:00 PM
Individuals with schizophrenia exhibit region-specific reductions in dendritic spine densities across cortical regions involved in visual-spatial working memory. ja.ma/48dYiTW
“GABA-glutamate corelease is functionally inhibitory or excitatory …., supporting a homeostatic role for GABA-glutamate cotransmission with broad implications for disorders of imbalanced motivation.”
GABA-glutamate corelease is a mechanism for state-dependent neurotransmission https://www.biorxiv.org/content/10.1101/2025.11.19.689286v1
November 20, 2025 at 6:14 PM
“GABA-glutamate corelease is functionally inhibitory or excitatory …., supporting a homeostatic role for GABA-glutamate cotransmission with broad implications for disorders of imbalanced motivation.”
Reposted by Graham Murray
Let me present the Spoon Illusion 🙂🥄
This has been in the works for over a decade when we were just goofing around testing sound localisation in my in-laws' kitchen... But we finally managed to do some reasonably controlled experiments on this. #psychscisky #neuroskyence
doi.org/10.1177/0301...
This has been in the works for over a decade when we were just goofing around testing sound localisation in my in-laws' kitchen... But we finally managed to do some reasonably controlled experiments on this. #psychscisky #neuroskyence
doi.org/10.1177/0301...
November 19, 2025 at 9:20 PM
Let me present the Spoon Illusion 🙂🥄
This has been in the works for over a decade when we were just goofing around testing sound localisation in my in-laws' kitchen... But we finally managed to do some reasonably controlled experiments on this. #psychscisky #neuroskyence
doi.org/10.1177/0301...
This has been in the works for over a decade when we were just goofing around testing sound localisation in my in-laws' kitchen... But we finally managed to do some reasonably controlled experiments on this. #psychscisky #neuroskyence
doi.org/10.1177/0301...
Reposted by Graham Murray
1) INFO FOR RESEARCHERS: The charity ME Research UK (MERUK) has an open call for PhD-level research funding.
Applicants should submit an Outline Proposal Form before Friday, 9 January 2026.
Applicants should submit an Outline Proposal Form before Friday, 9 January 2026.
November 18, 2025 at 2:30 PM
1) INFO FOR RESEARCHERS: The charity ME Research UK (MERUK) has an open call for PhD-level research funding.
Applicants should submit an Outline Proposal Form before Friday, 9 January 2026.
Applicants should submit an Outline Proposal Form before Friday, 9 January 2026.
Reposted by Graham Murray
I wrote about my knee injury and recent surgery, Oliver Sacks's "A Leg to Stand On", and how a zombie Calvinism continues to distort the American health care system:
open.substack.com/pub/kathrynp...
open.substack.com/pub/kathrynp...
"A Leg to Stand On"
Lessons in solidarity from knee surgery, physical therapy, and Oliver Sacks
open.substack.com
November 17, 2025 at 6:40 PM
I wrote about my knee injury and recent surgery, Oliver Sacks's "A Leg to Stand On", and how a zombie Calvinism continues to distort the American health care system:
open.substack.com/pub/kathrynp...
open.substack.com/pub/kathrynp...
Reposted by Graham Murray
Our study aims to understand psychosis, and improve outcomes for individuals with psychosis. By intervening early, we will provide timely support and care, ultimately enhancing lives.
We reached 250 participants!
eim.digitrial.com
@oxhealthbrc.bsky.social @cpftresearch.bsky.social
We reached 250 participants!
eim.digitrial.com
@oxhealthbrc.bsky.social @cpftresearch.bsky.social
November 17, 2025 at 2:12 PM
Our study aims to understand psychosis, and improve outcomes for individuals with psychosis. By intervening early, we will provide timely support and care, ultimately enhancing lives.
We reached 250 participants!
eim.digitrial.com
@oxhealthbrc.bsky.social @cpftresearch.bsky.social
We reached 250 participants!
eim.digitrial.com
@oxhealthbrc.bsky.social @cpftresearch.bsky.social
Reposted by Graham Murray
Beautifully written, funny, and important. Also ouch.
I wrote about my knee injury and recent surgery, Oliver Sacks's "A Leg to Stand On", and how a zombie Calvinism continues to distort the American health care system:
open.substack.com/pub/kathrynp...
open.substack.com/pub/kathrynp...
"A Leg to Stand On"
Lessons in solidarity from knee surgery, physical therapy, and Oliver Sacks
open.substack.com
November 17, 2025 at 7:01 PM
Beautifully written, funny, and important. Also ouch.
Reposted by Graham Murray
The importance of the departmental tea room where you can bump into anyone ....the importance of hearing diverse views. Today's post: The Importance of Community occamstypewriter.org/athenedonald...
The Importance of Community | Athene Donald's Blog
occamstypewriter.org
November 16, 2025 at 8:30 PM
The importance of the departmental tea room where you can bump into anyone ....the importance of hearing diverse views. Today's post: The Importance of Community occamstypewriter.org/athenedonald...
Reposted by Graham Murray
For lovers of @ourworldindata.org - we have improved our search functionality! Great work by the team at the backend to improve user experience. Enjoy!
ourworldindata.org/introducing-...
ourworldindata.org/introducing-...
Introducing our new, more powerful search
Finding what you’re looking for, or discovering something new, has never been easier.
ourworldindata.org
November 14, 2025 at 5:58 PM
For lovers of @ourworldindata.org - we have improved our search functionality! Great work by the team at the backend to improve user experience. Enjoy!
ourworldindata.org/introducing-...
ourworldindata.org/introducing-...
Reposted by Graham Murray
My review of #Crick by @matthewcobb.bsky.social has been published online by @science.org. The book is lucid, beautifully crafted, and compelling. It will instantly become the definitive guide to this extraordinary individual’s life and work.
November 13, 2025 at 8:14 PM
My review of #Crick by @matthewcobb.bsky.social has been published online by @science.org. The book is lucid, beautifully crafted, and compelling. It will instantly become the definitive guide to this extraordinary individual’s life and work.
Reposted by Graham Murray
Jonny Smallwood @themindwanders.bsky.social was a beloved friend and mentor. He was taken from us too soon. His was a beautiful mind who understood the beauty of minds. As ever before, his kind voice guides me and his work will continue. We miss you Jonny. www.cbs.mpg.de/news/obituar...
Obituary – Jonathan Smallwood
www.cbs.mpg.de
November 13, 2025 at 3:19 PM
Jonny Smallwood @themindwanders.bsky.social was a beloved friend and mentor. He was taken from us too soon. His was a beautiful mind who understood the beauty of minds. As ever before, his kind voice guides me and his work will continue. We miss you Jonny. www.cbs.mpg.de/news/obituar...
Reposted by Graham Murray
Addendum: I quickly wrote something partially about the results, and the potential for misunderstanding, but also about history's profound irony.
open.substack.com/pub/arutherf...
open.substack.com/pub/arutherf...
November 13, 2025 at 8:33 AM
Addendum: I quickly wrote something partially about the results, and the potential for misunderstanding, but also about history's profound irony.
open.substack.com/pub/arutherf...
open.substack.com/pub/arutherf...
Reposted by Graham Murray
at last. Expression of concern has appeared on BMJ stem cell paper with 44 comments
pubpeer.com/publications...
pubpeer.com/publications...
PubPeer - Prevention of acute myocardial infarction induced heart fail...
There are comments on PubPeer for publication: Prevention of acute myocardial infarction induced heart failure by intracoronary infusion of mesenchymal stem cells: phase 3 randomised clinical trial (P...
pubpeer.com
November 12, 2025 at 8:44 PM
at last. Expression of concern has appeared on BMJ stem cell paper with 44 comments
pubpeer.com/publications...
pubpeer.com/publications...
Reposted by Graham Murray
That’s quite the entrance to bluesky Loic 😅!!
November 12, 2025 at 7:08 PM
That’s quite the entrance to bluesky Loic 😅!!
Reposted by Graham Murray
First time on Bsky and first big announcement!
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
Estimation and mapping of the missing heritability of human phenotypes - Nature
WGS data were used from 347,630 individuals with European ancestry in the UK Biobank to obtain high-precision estimates of coding and non-coding rare variant heritability for 34 co...
www.nature.com
November 12, 2025 at 5:57 PM
First time on Bsky and first big announcement!
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
I am excited to announce that our new study explaining the missing heritability of many phenotypes using WGS data from ~347,000 UK Biobank participants has just been published in @Nature.
Our manuscript is here: www.nature.com/articles/s41....
🧠🩺
A MH trust has asked me a question and some of you may be better placed to help -
Does anyone know of a 136 process where a non-s12 doctor "triages" all 136 detentions on arrival at the PoS ahead of the AMHP-led assessment?
1/
Does anyone know of a 136 process where a non-s12 doctor "triages" all 136 detentions on arrival at the PoS ahead of the AMHP-led assessment?
1/
November 12, 2025 at 1:17 PM
🧠🩺
Reposted by Graham Murray
Come and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here.
www.cam.ac.uk/jobs/faculty...
www.cam.ac.uk/jobs/faculty...
Faculty Position in Computational Biology
Applications are invited for an Assistant/ Associate Professorship in Computational Biology to commence on 1 April 2026 or shortly thereafter. This is a joint post between the Department of Applied
www.cam.ac.uk
November 11, 2025 at 9:05 PM
Come and join us here in Cambridge! Applications open for a new faculty position, for a researcher in computational and/or theoretical biology, based jointly in Genetics and Mathematics. Happy to answer questions about research, teaching and working here.
www.cam.ac.uk/jobs/faculty...
www.cam.ac.uk/jobs/faculty...
Reposted by Graham Murray
Gift link!
“To reckon with Watson’s legacy, then, we propose celebrating what he wouldn’t—or couldn’t—recognize: the shared intelligence of the human race, which can produce miracles and wonders, even as each of us, individually, is so terribly fallible.“
“To reckon with Watson’s legacy, then, we propose celebrating what he wouldn’t—or couldn’t—recognize: the shared intelligence of the human race, which can produce miracles and wonders, even as each of us, individually, is so terribly fallible.“
The Paradox of James Watson
The discovery of DNA was evidence of how deeply interconnected humans are, but the late scientist saw only difference.
www.theatlantic.com
November 10, 2025 at 6:56 PM
Gift link!
“To reckon with Watson’s legacy, then, we propose celebrating what he wouldn’t—or couldn’t—recognize: the shared intelligence of the human race, which can produce miracles and wonders, even as each of us, individually, is so terribly fallible.“
“To reckon with Watson’s legacy, then, we propose celebrating what he wouldn’t—or couldn’t—recognize: the shared intelligence of the human race, which can produce miracles and wonders, even as each of us, individually, is so terribly fallible.“
Reposted by Graham Murray
Gift link:
The Paradox of James Watson
The discovery of DNA was evidence of how deeply interconnected humans are, but the late scientist saw only difference.
www.theatlantic.com
November 10, 2025 at 7:12 PM
Gift link:
Reposted by Graham Murray
Very excited to be able to finally share our latest work, "Cloud computing for equitable, data-driven dementia medicine," just published in The Lancet Digital Health!
authors.elsevier.com/sd/article/S...
more info in thread: 🧵
authors.elsevier.com/sd/article/S...
more info in thread: 🧵
Cloud computing for equitable, data-driven dementia medicine
Dementia poses an increasing global health challenge, and the introduction of new
drugs with diverse activity profiles underscores the need for the rapid development
and deployment of tailored predict...
www.thelancet.com
November 10, 2025 at 2:23 PM
Very excited to be able to finally share our latest work, "Cloud computing for equitable, data-driven dementia medicine," just published in The Lancet Digital Health!
authors.elsevier.com/sd/article/S...
more info in thread: 🧵
authors.elsevier.com/sd/article/S...
more info in thread: 🧵
Reposted by Graham Murray
We just published a paper in PNAS, showing microstructural changes to the hippocampus in aging and presymptomatic Alzheimer's disease - in humans, in vivo.
We continue to show the value of structural MRI beyond simply measuring large-scale atrophy!
Read here: ow.ly/1NvV50XkXnX
We continue to show the value of structural MRI beyond simply measuring large-scale atrophy!
Read here: ow.ly/1NvV50XkXnX
November 9, 2025 at 5:00 PM
We just published a paper in PNAS, showing microstructural changes to the hippocampus in aging and presymptomatic Alzheimer's disease - in humans, in vivo.
We continue to show the value of structural MRI beyond simply measuring large-scale atrophy!
Read here: ow.ly/1NvV50XkXnX
We continue to show the value of structural MRI beyond simply measuring large-scale atrophy!
Read here: ow.ly/1NvV50XkXnX
Reposted by Graham Murray
New paper on everyone’s favourite topic, QC!
We show why you should do genotype-level QC on your WGS data
www.biorxiv.org/content/10.1...
Very real quotes about this paper -
“The most exciting, mind-blowing paper of the year!”
“On a par with Fisher 1918”
“I read it every night. Just so beautiful”
We show why you should do genotype-level QC on your WGS data
www.biorxiv.org/content/10.1...
Very real quotes about this paper -
“The most exciting, mind-blowing paper of the year!”
“On a par with Fisher 1918”
“I read it every night. Just so beautiful”
Genotype-level quality control substantially reduces error rates in population-scale whole-genome sequencing
Population-scale whole-genome sequencing data will contain many individual-level genotype errors, even after allele-level quality control (QC). We establish the need for genotype-level QC using UK Bio...
www.biorxiv.org
November 8, 2025 at 9:31 AM
New paper on everyone’s favourite topic, QC!
We show why you should do genotype-level QC on your WGS data
www.biorxiv.org/content/10.1...
Very real quotes about this paper -
“The most exciting, mind-blowing paper of the year!”
“On a par with Fisher 1918”
“I read it every night. Just so beautiful”
We show why you should do genotype-level QC on your WGS data
www.biorxiv.org/content/10.1...
Very real quotes about this paper -
“The most exciting, mind-blowing paper of the year!”
“On a par with Fisher 1918”
“I read it every night. Just so beautiful”