Filipe De Vadder
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filipedevadder.bsky.social
Filipe De Vadder
@filipedevadder.bsky.social
360 followers 440 following 140 posts
@cnrs.bsky.social researcher at @IGFLyon.bsky.social, working on #microbiota #physiology #nutrition #intestine. I like the gut, beer, metal and rugby.
Posts Replies Media Videos
Reposted by Filipe De Vadder
cnrs.fr
Is open science on the cusp of taking a new turn in the current context of international tension twinned with AI's rapid rise? Sylvie Rousset, the director of the CNRS's Open Research Data Department takes stock of the organisation progress in this area.
Open science – the CNRS's successes
Is open science on the cusp of taking a new turn in the current context of international tension twinned with AI's rapid rise, for better or for worse?
www.cnrs.fr
November 25, 2025 at 3:11 PM
Reposted by Filipe De Vadder
blekhman.bsky.social
I wrote about the recent autism-microbiome paper, why I think it's the most important microbiome paper this year, and what it says about the field

open.substack.com/pub/blekhman...
The Autism-Microbiome Hypothesis Is Falling Apart
Why this new review paper should be required reading for every microbiome researcher
open.substack.com
November 19, 2025 at 5:12 PM
filipedevadder.bsky.social
New Neuron paper by Mitchell, Dahly, Bishop tears apart the “autism is caused by the microbiome” story. Tiny n, noisy 16S, contradictory taxa, vague “dysbiosis”. It reads like an autopsy of a hype bubble.
www.cell.com/neuron/fullt...
Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism
Claims that the gut microbiome causally contributes to autism regularly appear in the scientific literature and popular press. Mitchell et al. critically examine influential studies underpinning these...
www.cell.com
November 19, 2025 at 3:03 PM
filipedevadder.bsky.social
Every year I am surprised to see universities celebrating their “highly cited researchers” from a closed index, owned by Clarivate. How is it calculated? Who knows. Is it a skewed index? Of course it is. Did these universities not sign the DORA agreement? Raoult was a highly cited researcher too…
November 15, 2025 at 9:41 AM
filipedevadder.bsky.social
Je garde cette image,
D’horreur et d’effroi,
À jamais gravée en moi.

youtu.be/5FrunmQctu4?...
Tagada Jones Vendredi 13 - Officiel
YouTube video by TAGADA JONES
youtu.be
November 13, 2025 at 7:12 AM
Reposted by Filipe De Vadder
erictopol.bsky.social
The baseless protein craze
"You just create an inefficient system where your body gets very good at wasting food protein”
“It’s really frustrating because there isn’t evidence to support the claims that they’re making"
Feature @nature.com
nature.com/articles/d41...
How much protein do you really need? What the science says
Fitness influencers promote super-high-protein diets, but studies show there’s only so much the body can use.
nature.com
November 12, 2025 at 2:40 PM
Reposted by Filipe De Vadder
francoisleulier.bsky.social
Latest from the lab by @longweibai.bsky.social
www.biorxiv.org/content/10.1...
1/6
A nutrient-sensitive enterokine coordinates developmental plasticity through inter-organ signalling
Animal survival in fluctuating environments depend on the ability to modulate their developmental pace in response to nutrient availability, a phenomenon known as developmental plasticity. In Drosophi...
www.biorxiv.org
November 8, 2025 at 2:44 PM
Reposted by Filipe De Vadder
cassouman40.bsky.social
La crédibilité se mesure en acte, pas en mots!
En tant qu'auteur #GIEC, je ne me sens nullement reconnu par ce discours; je me sens trahi par des paroles qui n'ont plus de valeurs
#colère
La désinformation ne va pas se combattre par du "mots contre mots" mais par du "actes contre mots".
Un fil 🧵
1/
quotaclimat.org QuotaClimat ⏱ @quotaclimat.org · 19d
🔥 Des années de travail pour obtenir une telle reconnaissance politique : hier, Emmanuel Macron a déclaré à la COP30 que « la désinformation climatique fait peser une menace sur nos démocraties, sur l’agenda de Paris et donc sur notre sécurité collective ».
November 8, 2025 at 4:38 PM
filipedevadder.bsky.social
Yes please! And also shitty reference genes for qPCR (whose stability is not even checked on geNorm).
aliciakowaltowski.bsky.social Alicia Kowaltowski @aliciakowaltowski.bsky.social · 20d
Can we please stop using GAPDH as a "loading control", particularly in metabolic studies??
November 6, 2025 at 4:24 PM
Reposted by Filipe De Vadder
aliciakowaltowski.bsky.social
Can we please stop using GAPDH as a "loading control", particularly in metabolic studies??
November 6, 2025 at 1:11 PM
Reposted by Filipe De Vadder
mixlamalice.bsky.social
J'y reviens mais entendre ça dans un moment où aucune commande, aucune mission, aucun remboursement, aucun recrutement ne peut se faire sans "effort", ne parlons même pas de faire de la recherche mais simplement de travailler, c'est vraiment dur à entendre (voir aussi le fil d'@aigverte.bsky.social)
cedricbrun.bsky.social Cédric Brun @cedricbrun.bsky.social · 26d
Quand notre ministre de tutelle nous insulte devant la représentation nationale. "Bande de nuls" "complètement à la ramasse".
Nous reprocher des taux de réussite faible à Horizon Europe et ERC, quand manquent les moyens pour assurer nos missions de service public. Surtout changez rien!👌
October 31, 2025 at 4:23 PM
Reposted by Filipe De Vadder
mixlamalice.bsky.social
Fascinant. Il faut écouter ça. Outre le langage ordurier faussement parler vrai mais vraiment insultant, que dit-il? Il dit que le taux de succès était bon mais que selon leurs critères on ne déposait pas assez d'erc.
cedricbrun.bsky.social Cédric Brun @cedricbrun.bsky.social · 26d
Quand notre ministre de tutelle nous insulte devant la représentation nationale. "Bande de nuls" "complètement à la ramasse".
Nous reprocher des taux de réussite faible à Horizon Europe et ERC, quand manquent les moyens pour assurer nos missions de service public. Surtout changez rien!👌
October 31, 2025 at 9:39 AM
Reposted by Filipe De Vadder
blibep.bsky.social
La @socneuro.bsky.social a publié avec plusieurs Sociétés savantes et Associations de patients une tribune dans Le Monde « Budget 2026 : La taxation des expérimentations animales mettrait en péril la recherche en France » : www.lemonde.fr/sciences/art...
#plf2026 @sneuroendo.bsky.social
Budget 2026 : « La taxation des expérimentations animales mettrait en péril la recherche en France »
TRIBUNE. Dans une tribune au « Monde », des représentants de sociétés savantes, de fondations, d’associations et de réseaux scientifiques mettent en garde contre le dépôt d’amendements au projet de lo...
www.lemonde.fr
October 28, 2025 at 5:05 PM
Reposted by Filipe De Vadder
microbiome.bsky.social
We selected the laziest mouse at each round to inoculate the next batch of germfree mice: over rounds of selection and passaging, behavior shifted without changes to the mouse genome: rdcu.be/eM3rO
🦠🧫
Selection and transmission of the gut microbiome alone can shift mammalian behavior
Nature Communications - Here, the authors present evidence that the gut microbiome alone, without changes in the host genome, can shape how animals respond to selection, identifying a bacterium and...
rdcu.be
October 28, 2025 at 7:51 AM
Reposted by Filipe De Vadder
pawelburkhardt.bsky.social
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience

Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E

@jeffcolgren.bsky.social @msarscentre.bsky.social
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
rdcu.be
October 27, 2025 at 6:48 PM
Reposted by Filipe De Vadder
cp-neuron.bsky.social
An enteric-DRG pathway for interoception and visceral pain in mice
Wang et al. reveal a neuroanatomical and functional crosstalk between cholinergic enteric neurons and sensory neurons of the dorsal root ganglia that mediates colonic interoception. While this pathway typically elicits non-aversive reflexes under physiological conditions, inflammatory colitis triggers plasticity that transforms its output to promote aversive behaviors.
dlvr.it
October 23, 2025 at 3:24 PM
filipedevadder.bsky.social
@mads100tist.bsky.social you will love this one. “Hey, give all your ideas to Springer-Nature, we’re totally cool with that. We already did it when we bought Research Squire and protocols.io but hey, keep feeding us please!”
October 21, 2025 at 1:21 PM
Reposted by Filipe De Vadder
faquin.bsky.social
Les risques de dérives sont énormes. Bush avait financé la génétique légale à hauteur de plusieurs millions de $ au prétexte de la guerre contre le terrorisme. Résultat c'est aussi utilisé pour traquer les racisés de manière plus globale. Aucune surprise, on prend le risque de tendre vers ça aussi.
October 20, 2025 at 4:05 PM
filipedevadder.bsky.social
#ProudPI 🎓
Thrilled to share that @ameliejoly.bsky.social received the thesis prize of the @sneuroendo.bsky.social, huge congratulations! 👏
And @lucasrebiffe.bsky.social is presenting the follow-up of the project in a great poster. Exciting to see the team’s work shining! 💪
#SNE25
2025 Thesis Prize Winner is Amélie Joly Amélie presenting her work Lucas presenting his poster
October 10, 2025 at 12:02 PM
filipedevadder.bsky.social
Our new study, just accepted in the Journal of the Endocrine Society
👉 doi.org/10.1210/jend...
We found that semaglutide, beyond its metabolic effects, can exacerbate growth stunting in juvenile mice by reducing energy metabolism, a context-dependent effect of GLP-1 signaling.
pendingpublications
Pending Publication
doi.org
October 9, 2025 at 4:09 PM
filipedevadder.bsky.social
La science est formelle: le prochain gouvernement aura une durée négative
October 6, 2025 at 8:47 AM
Reposted by Filipe De Vadder
gonzaparra.bsky.social
After months of buildup, it’s finally real! 🎉 The Evolutionary Systems Biophysics Group (ESBG) is officially alive at @bsc-cns.bsky.social . Proud to start this new adventure as a Ramon y Cajal Junior Group Leader🧬
Thanks to all who have been part of this process!
tinyurl.com/4r9vf4zx
October 2, 2025 at 8:06 AM
Reposted by Filipe De Vadder
science.org
Jane Goodall has died at the age of 91.

In 2020, Goodall spoke with Science Editor-in-Chief H. Holden Thorp for a #ScienceEditorial reflecting on the 60th anniversary of her arrival in Gombe to study wild chimpanzees. Read more: https://scim.ag/472Chb8
"… Goodall’s … is a story of genuine scientific curiosity, determination, and respect for nature and humanity …" H. Holden Thorp, Editor-in-chief, Science journals
October 1, 2025 at 7:13 PM
Reposted by Filipe De Vadder
sncs-fsu.bsky.social
Le SNCS-FSU apporte son soutien à notre collègue Gabriel #Zucman dont le travail de recherche rigoureux en économie a été caricaturé et dénigré par Bernard Arnault

Le SNCS-FSU dénonce plus largement les attaques contre les libertés académiques 👇
sncs.fr/2025/09/25/l...

#ESR #VeilleESR
September 30, 2025 at 6:54 AM
Reposted by Filipe De Vadder
cp-cellhostmicrobe.bsky.social
Microbiota extends reproductive lifespan:

Germ-free female mice undergo accelerated primordial follicle loss & reduced reproductive capacity that are restored upon post-natal colonization. Microbial SCFAs & fiber mitigates ovarian dysfunction
www.cell.com/cell-host-mi...
The microbiota extends the reproductive lifespan of mice by safeguarding the ovarian reserve
Munyoki et al. demonstrate that gut microbiota extend the female reproductive lifespan by safeguarding the ovarian reserve. Germ-free mice undergo accelerated primordial follicle loss and reduced repr...
www.cell.com
September 29, 2025 at 7:54 PM