Filipe De Vadder
@filipedevadder.bsky.social
@cnrs.bsky.social researcher at @IGFLyon.bsky.social, working on #microbiota #physiology #nutrition #intestine. I like the gut, beer, metal and rugby.
Reposted by Filipe De Vadder
Expliquer le consumérisme à base de dopamine, on dirait un challenge où les neurosciences sont instrumentalisées pour ne jamais prononcer le mot "capitalisme".
C'est confondre le mécanisme et la cause - un peu comme si on repondait "pourquoi on va au boulot" par "parce que le métro nous y emmène".
C'est confondre le mécanisme et la cause - un peu comme si on repondait "pourquoi on va au boulot" par "parce que le métro nous y emmène".
November 28, 2025 at 7:09 AM
Expliquer le consumérisme à base de dopamine, on dirait un challenge où les neurosciences sont instrumentalisées pour ne jamais prononcer le mot "capitalisme".
C'est confondre le mécanisme et la cause - un peu comme si on repondait "pourquoi on va au boulot" par "parce que le métro nous y emmène".
C'est confondre le mécanisme et la cause - un peu comme si on repondait "pourquoi on va au boulot" par "parce que le métro nous y emmène".
Once again some bullshit published in Scientific Reports (the same journal that published a paper on “neutrosophic statistics”, a “nonlinear model of a love story”, or a correlation between BMI and dishonesty. What a surprise.
"Runctitiononal features"? "Medical fymblal"? "1 Tol Line storee"? This gets worse the longer you look at it. But it's got to be good, because it was published in Nature Scientific Reports last week: www.nature.com/articles/s41... h/t @asa.tsbalans.se
November 27, 2025 at 10:50 PM
Once again some bullshit published in Scientific Reports (the same journal that published a paper on “neutrosophic statistics”, a “nonlinear model of a love story”, or a correlation between BMI and dishonesty. What a surprise.
Reposted by Filipe De Vadder
Is open science on the cusp of taking a new turn in the current context of international tension twinned with AI's rapid rise? Sylvie Rousset, the director of the CNRS's Open Research Data Department takes stock of the organisation progress in this area.
Open science – the CNRS's successes
Is open science on the cusp of taking a new turn in the current context of international tension twinned with AI's rapid rise, for better or for worse?
www.cnrs.fr
November 25, 2025 at 3:11 PM
Is open science on the cusp of taking a new turn in the current context of international tension twinned with AI's rapid rise? Sylvie Rousset, the director of the CNRS's Open Research Data Department takes stock of the organisation progress in this area.
Reposted by Filipe De Vadder
I wrote about the recent autism-microbiome paper, why I think it's the most important microbiome paper this year, and what it says about the field
open.substack.com/pub/blekhman...
open.substack.com/pub/blekhman...
The Autism-Microbiome Hypothesis Is Falling Apart
Why this new review paper should be required reading for every microbiome researcher
open.substack.com
November 19, 2025 at 5:12 PM
I wrote about the recent autism-microbiome paper, why I think it's the most important microbiome paper this year, and what it says about the field
open.substack.com/pub/blekhman...
open.substack.com/pub/blekhman...
New Neuron paper by Mitchell, Dahly, Bishop tears apart the “autism is caused by the microbiome” story. Tiny n, noisy 16S, contradictory taxa, vague “dysbiosis”. It reads like an autopsy of a hype bubble.
www.cell.com/neuron/fullt...
www.cell.com/neuron/fullt...
Conceptual and methodological flaws undermine claims of a link between the gut microbiome and autism
Claims that the gut microbiome causally contributes to autism regularly appear in
the scientific literature and popular press. Mitchell et al. critically examine influential
studies underpinning these...
www.cell.com
November 19, 2025 at 3:03 PM
New Neuron paper by Mitchell, Dahly, Bishop tears apart the “autism is caused by the microbiome” story. Tiny n, noisy 16S, contradictory taxa, vague “dysbiosis”. It reads like an autopsy of a hype bubble.
www.cell.com/neuron/fullt...
www.cell.com/neuron/fullt...
Every year I am surprised to see universities celebrating their “highly cited researchers” from a closed index, owned by Clarivate. How is it calculated? Who knows. Is it a skewed index? Of course it is. Did these universities not sign the DORA agreement? Raoult was a highly cited researcher too…
November 15, 2025 at 9:41 AM
Every year I am surprised to see universities celebrating their “highly cited researchers” from a closed index, owned by Clarivate. How is it calculated? Who knows. Is it a skewed index? Of course it is. Did these universities not sign the DORA agreement? Raoult was a highly cited researcher too…
Tagada Jones Vendredi 13 - Officiel
YouTube video by TAGADA JONES
youtu.be
November 13, 2025 at 7:12 AM
Reposted by Filipe De Vadder
The baseless protein craze
"You just create an inefficient system where your body gets very good at wasting food protein”
“It’s really frustrating because there isn’t evidence to support the claims that they’re making"
Feature @nature.com
nature.com/articles/d41...
"You just create an inefficient system where your body gets very good at wasting food protein”
“It’s really frustrating because there isn’t evidence to support the claims that they’re making"
Feature @nature.com
nature.com/articles/d41...
How much protein do you really need? What the science says
Fitness influencers promote super-high-protein diets, but studies show there’s only so much the body can use.
nature.com
November 12, 2025 at 2:40 PM
The baseless protein craze
"You just create an inefficient system where your body gets very good at wasting food protein”
“It’s really frustrating because there isn’t evidence to support the claims that they’re making"
Feature @nature.com
nature.com/articles/d41...
"You just create an inefficient system where your body gets very good at wasting food protein”
“It’s really frustrating because there isn’t evidence to support the claims that they’re making"
Feature @nature.com
nature.com/articles/d41...
Reposted by Filipe De Vadder
Reposted by Filipe De Vadder
La crédibilité se mesure en acte, pas en mots!
En tant qu'auteur #GIEC, je ne me sens nullement reconnu par ce discours; je me sens trahi par des paroles qui n'ont plus de valeurs
#colère
La désinformation ne va pas se combattre par du "mots contre mots" mais par du "actes contre mots".
Un fil 🧵
1/
En tant qu'auteur #GIEC, je ne me sens nullement reconnu par ce discours; je me sens trahi par des paroles qui n'ont plus de valeurs
#colère
La désinformation ne va pas se combattre par du "mots contre mots" mais par du "actes contre mots".
Un fil 🧵
1/
🔥 Des années de travail pour obtenir une telle reconnaissance politique : hier, Emmanuel Macron a déclaré à la COP30 que « la désinformation climatique fait peser une menace sur nos démocraties, sur l’agenda de Paris et donc sur notre sécurité collective ».
November 8, 2025 at 4:38 PM
Yes please! And also shitty reference genes for qPCR (whose stability is not even checked on geNorm).
Can we please stop using GAPDH as a "loading control", particularly in metabolic studies??
November 6, 2025 at 4:24 PM
Yes please! And also shitty reference genes for qPCR (whose stability is not even checked on geNorm).
Reposted by Filipe De Vadder
Can we please stop using GAPDH as a "loading control", particularly in metabolic studies??
November 6, 2025 at 1:11 PM
Can we please stop using GAPDH as a "loading control", particularly in metabolic studies??
Reposted by Filipe De Vadder
La @socneuro.bsky.social a publié avec plusieurs Sociétés savantes et Associations de patients une tribune dans Le Monde « Budget 2026 : La taxation des expérimentations animales mettrait en péril la recherche en France » : www.lemonde.fr/sciences/art...
#plf2026 @sneuroendo.bsky.social
#plf2026 @sneuroendo.bsky.social
Budget 2026 : « La taxation des expérimentations animales mettrait en péril la recherche en France »
TRIBUNE. Dans une tribune au « Monde », des représentants de sociétés savantes, de fondations, d’associations et de réseaux scientifiques mettent en garde contre le dépôt d’amendements au projet de lo...
www.lemonde.fr
October 28, 2025 at 5:05 PM
La @socneuro.bsky.social a publié avec plusieurs Sociétés savantes et Associations de patients une tribune dans Le Monde « Budget 2026 : La taxation des expérimentations animales mettrait en péril la recherche en France » : www.lemonde.fr/sciences/art...
#plf2026 @sneuroendo.bsky.social
#plf2026 @sneuroendo.bsky.social
Reposted by Filipe De Vadder
We selected the laziest mouse at each round to inoculate the next batch of germfree mice: over rounds of selection and passaging, behavior shifted without changes to the mouse genome: rdcu.be/eM3rO
🦠🧫
🦠🧫
Selection and transmission of the gut microbiome alone can shift mammalian behavior
Nature Communications - Here, the authors present evidence that the gut microbiome alone, without changes in the host genome, can shape how animals respond to selection, identifying a bacterium and...
rdcu.be
October 28, 2025 at 7:51 AM
We selected the laziest mouse at each round to inoculate the next batch of germfree mice: over rounds of selection and passaging, behavior shifted without changes to the mouse genome: rdcu.be/eM3rO
🦠🧫
🦠🧫
Reposted by Filipe De Vadder
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
The evolutionary origins of synaptic proteins and their changing roles in different organisms across evolution
Nature Reviews Neuroscience - Recent studies have shed further light on the evolutionary origins of chemical synapses, In this Review, Colgren and Burkhardt explore how ancient proteins were...
rdcu.be
October 27, 2025 at 6:48 PM
First neurons didn’t appear overnight. We trace their roots to ancient secretory cells - showing how lifestyle & behavior shaped the evolution of first synapses.🧠🌊 #Evolution #Neuroscience
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
Our latest in @natrevneuro.nature.com
Link: rdcu.be/eMX3E
@jeffcolgren.bsky.social @msarscentre.bsky.social
Reposted by Filipe De Vadder
@mads100tist.bsky.social you will love this one. “Hey, give all your ideas to Springer-Nature, we’re totally cool with that. We already did it when we bought Research Squire and protocols.io but hey, keep feeding us please!”
October 21, 2025 at 1:21 PM
@mads100tist.bsky.social you will love this one. “Hey, give all your ideas to Springer-Nature, we’re totally cool with that. We already did it when we bought Research Squire and protocols.io but hey, keep feeding us please!”
Reposted by Filipe De Vadder
Les risques de dérives sont énormes. Bush avait financé la génétique légale à hauteur de plusieurs millions de $ au prétexte de la guerre contre le terrorisme. Résultat c'est aussi utilisé pour traquer les racisés de manière plus globale. Aucune surprise, on prend le risque de tendre vers ça aussi.
October 20, 2025 at 4:05 PM
Les risques de dérives sont énormes. Bush avait financé la génétique légale à hauteur de plusieurs millions de $ au prétexte de la guerre contre le terrorisme. Résultat c'est aussi utilisé pour traquer les racisés de manière plus globale. Aucune surprise, on prend le risque de tendre vers ça aussi.
#ProudPI 🎓
Thrilled to share that @ameliejoly.bsky.social received the thesis prize of the @sneuroendo.bsky.social, huge congratulations! 👏
And @lucasrebiffe.bsky.social is presenting the follow-up of the project in a great poster. Exciting to see the team’s work shining! 💪
#SNE25
Thrilled to share that @ameliejoly.bsky.social received the thesis prize of the @sneuroendo.bsky.social, huge congratulations! 👏
And @lucasrebiffe.bsky.social is presenting the follow-up of the project in a great poster. Exciting to see the team’s work shining! 💪
#SNE25
October 10, 2025 at 12:02 PM
#ProudPI 🎓
Thrilled to share that @ameliejoly.bsky.social received the thesis prize of the @sneuroendo.bsky.social, huge congratulations! 👏
And @lucasrebiffe.bsky.social is presenting the follow-up of the project in a great poster. Exciting to see the team’s work shining! 💪
#SNE25
Thrilled to share that @ameliejoly.bsky.social received the thesis prize of the @sneuroendo.bsky.social, huge congratulations! 👏
And @lucasrebiffe.bsky.social is presenting the follow-up of the project in a great poster. Exciting to see the team’s work shining! 💪
#SNE25
Our new study, just accepted in the Journal of the Endocrine Society
👉 doi.org/10.1210/jend...
We found that semaglutide, beyond its metabolic effects, can exacerbate growth stunting in juvenile mice by reducing energy metabolism, a context-dependent effect of GLP-1 signaling.
👉 doi.org/10.1210/jend...
We found that semaglutide, beyond its metabolic effects, can exacerbate growth stunting in juvenile mice by reducing energy metabolism, a context-dependent effect of GLP-1 signaling.
pendingpublications
Pending Publication
doi.org
October 9, 2025 at 4:09 PM
Our new study, just accepted in the Journal of the Endocrine Society
👉 doi.org/10.1210/jend...
We found that semaglutide, beyond its metabolic effects, can exacerbate growth stunting in juvenile mice by reducing energy metabolism, a context-dependent effect of GLP-1 signaling.
👉 doi.org/10.1210/jend...
We found that semaglutide, beyond its metabolic effects, can exacerbate growth stunting in juvenile mice by reducing energy metabolism, a context-dependent effect of GLP-1 signaling.
La science est formelle: le prochain gouvernement aura une durée négative
October 6, 2025 at 8:47 AM
La science est formelle: le prochain gouvernement aura une durée négative
Reposted by Filipe De Vadder
After months of buildup, it’s finally real! 🎉 The Evolutionary Systems Biophysics Group (ESBG) is officially alive at @bsc-cns.bsky.social . Proud to start this new adventure as a Ramon y Cajal Junior Group Leader🧬
Thanks to all who have been part of this process!
tinyurl.com/4r9vf4zx
Thanks to all who have been part of this process!
tinyurl.com/4r9vf4zx
October 2, 2025 at 8:06 AM
After months of buildup, it’s finally real! 🎉 The Evolutionary Systems Biophysics Group (ESBG) is officially alive at @bsc-cns.bsky.social . Proud to start this new adventure as a Ramon y Cajal Junior Group Leader🧬
Thanks to all who have been part of this process!
tinyurl.com/4r9vf4zx
Thanks to all who have been part of this process!
tinyurl.com/4r9vf4zx
Reposted by Filipe De Vadder
Jane Goodall has died at the age of 91.
In 2020, Goodall spoke with Science Editor-in-Chief H. Holden Thorp for a #ScienceEditorial reflecting on the 60th anniversary of her arrival in Gombe to study wild chimpanzees. Read more: https://scim.ag/472Chb8
In 2020, Goodall spoke with Science Editor-in-Chief H. Holden Thorp for a #ScienceEditorial reflecting on the 60th anniversary of her arrival in Gombe to study wild chimpanzees. Read more: https://scim.ag/472Chb8
October 1, 2025 at 7:13 PM
Jane Goodall has died at the age of 91.
In 2020, Goodall spoke with Science Editor-in-Chief H. Holden Thorp for a #ScienceEditorial reflecting on the 60th anniversary of her arrival in Gombe to study wild chimpanzees. Read more: https://scim.ag/472Chb8
In 2020, Goodall spoke with Science Editor-in-Chief H. Holden Thorp for a #ScienceEditorial reflecting on the 60th anniversary of her arrival in Gombe to study wild chimpanzees. Read more: https://scim.ag/472Chb8