Brigid Flanagan
@bflanaga.bsky.social
Research Operations Consultant | Book lover | Nurse | Former New Englander now back home in Ireland ...Co.Monaghan | News Hound | #clinicalresearch
Fabulous news!
Australia just recorded zero cervical cancer cases in women under 25 for the first time since records began in 1982. The amazing result of HPV vaccination.
November 28, 2025 at 8:47 PM
Fabulous news!
Great news for people with asthma!
An international clinical trial has found that participants who received injections of tezepelumab, a human monoclonal antibody, once every four weeks were able to reduce or even stop taking steroid medications for severe asthma entirely with no ill effects.
This is why science matters.
This is why science matters.
November 27, 2025 at 10:30 AM
Great news for people with asthma!
Reposted by Brigid Flanagan
Two exciting phase two trials show incredible success of mrna vaccines for seasonal flu with infectious symptoms prevented in some healthy individuals. 🧪🧵
Experimental mRNA flu vaccine shows superior efficacy against symptomatic illness
www.cidrap.umn.edu
November 26, 2025 at 6:42 AM
Two exciting phase two trials show incredible success of mrna vaccines for seasonal flu with infectious symptoms prevented in some healthy individuals. 🧪🧵
Reposted by Brigid Flanagan
A new study found the Trump administration’s cuts to NIH grants disrupted more than 380 clinical trials, affecting over 74,000 participants.
The cuts disproportionately impacted trials on infectious diseases and minority communities.
The cuts disproportionately impacted trials on infectious diseases and minority communities.
Federal cuts upended clinical trials. A new study reveals the toll.
Grants for 383 clinical trials were terminated and the funding disruptions affected more than 74,000 trial participants, according to new research.
www.washingtonpost.com
November 17, 2025 at 11:00 PM
A new study found the Trump administration’s cuts to NIH grants disrupted more than 380 clinical trials, affecting over 74,000 participants.
The cuts disproportionately impacted trials on infectious diseases and minority communities.
The cuts disproportionately impacted trials on infectious diseases and minority communities.
Reposted by Brigid Flanagan
From Paul Kim on leucovorin: "Proffering a proactive guarantee of approval on the basis of a limited, non-trial-based dossier effectively broadcasts that the FDA is prepared to approve new drugs without clinical trials."
www.milbank.org/quarterly/op...
www.milbank.org/quarterly/op...
The New Politics of New Drug Approval | Milbank Memorial Fund
As feared at the start of the second Trump Administration, the Food and Drug Administration (FDA) has proven a willing good soldier in fulfilling the
www.milbank.org
November 11, 2025 at 10:53 AM
From Paul Kim on leucovorin: "Proffering a proactive guarantee of approval on the basis of a limited, non-trial-based dossier effectively broadcasts that the FDA is prepared to approve new drugs without clinical trials."
www.milbank.org/quarterly/op...
www.milbank.org/quarterly/op...
Some good news for a change.
GOOD NEWS! Researchers have developed a new mRNA vaccine that has been shown to suppress abnormal blood vessel growth in the retina, offering hope to MILLIONS of patients with age-related vision loss. The vaccine triggered strong antibody responses that REDUCED retinal damage by UP TO 85%.
November 3, 2025 at 11:15 PM
Some good news for a change.
Reposted by Brigid Flanagan
Effectiveness of Colchicine for the Treatment of Long COVID: A Randomized Clinical Trial
jamanetwork.com/journals/jam...
"among adults with long COVID, colchicine did not improve functional capacity, respiratory function, or inflammatory markers."
#LongCovid #PASC
jamanetwork.com/journals/jam...
"among adults with long COVID, colchicine did not improve functional capacity, respiratory function, or inflammatory markers."
#LongCovid #PASC
Effectiveness of Colchicine for the Treatment of Long COVID
This randomized clinical trial evaluates the superiority of colchicine over placebo among adults with long COVID in improving functional outcome at 52 weeks from baseline.
jamanetwork.com
October 26, 2025 at 2:33 PM
Effectiveness of Colchicine for the Treatment of Long COVID: A Randomized Clinical Trial
jamanetwork.com/journals/jam...
"among adults with long COVID, colchicine did not improve functional capacity, respiratory function, or inflammatory markers."
#LongCovid #PASC
jamanetwork.com/journals/jam...
"among adults with long COVID, colchicine did not improve functional capacity, respiratory function, or inflammatory markers."
#LongCovid #PASC
100% agree. It is difficult to challenge misinformation when you cannot access the data to support your argument.
In general I think it's hard to combat scientific misinformation when some of the best research is locked behind an academic paywall, while lots of nonsense gets published free for everyone to read in predatory journals.
September 29, 2025 at 9:14 PM
100% agree. It is difficult to challenge misinformation when you cannot access the data to support your argument.
Reposted by Brigid Flanagan
🧪 New ACOG guidelines warn against cannabis use in pregnancy. Despite its use for nausea, mounting evidence links it to preterm birth, low birth weight, and neurocognitive delays in children. THC is known to cross the placenta and concentrate in the fetal brain.
#MedSky
#MedSky
Pregnant Women Should Not Use Cannabis, New Medical Guidelines Say
Marijuana during pregnancy is linked to poor birth outcomes and developmental delays in children, a leading medical society advised.
www.nytimes.com
September 23, 2025 at 3:51 AM
🧪 New ACOG guidelines warn against cannabis use in pregnancy. Despite its use for nausea, mounting evidence links it to preterm birth, low birth weight, and neurocognitive delays in children. THC is known to cross the placenta and concentrate in the fetal brain.
#MedSky
#MedSky
Correlation is not causation. Read the cited papers!
The papers that HHS cites to bolster their claim appear to have convinced many people that this is a legit scientific observation. But the citations actually show no correlation between Tylenol use and autism. PSA: Don't believe something because someone provides a citation. Go read the cited paper🧪
🧪
>77 million votes. Today the big reveal on autism: Tylenol. "I'm making these statements from me, I'm not making them from these doctors." youtu.be/esKFMCb_hYU?...
The viewer comments below the video are the only glimmer of hope.
>77 million votes. Today the big reveal on autism: Tylenol. "I'm making these statements from me, I'm not making them from these doctors." youtu.be/esKFMCb_hYU?...
The viewer comments below the video are the only glimmer of hope.
September 23, 2025 at 6:47 AM
Correlation is not causation. Read the cited papers!
Hardly a surprise!
“Conclusion:
After private equity acquisition, hospitals on average reduced salaries and staffing relative to nonacquired hospitals…This decreased capacity to deliver care may explain the increased patient transfers to other hospitals, shortened ICU lengths of stay, and increased ED mortality.” 🩺🧪
After private equity acquisition, hospitals on average reduced salaries and staffing relative to nonacquired hospitals…This decreased capacity to deliver care may explain the increased patient transfers to other hospitals, shortened ICU lengths of stay, and increased ED mortality.” 🩺🧪
Hospital Staffing and Patient Outcomes After Private Equity Acquisition | Annals of Internal Medicine
Background: After private equity acquisition, hospitals may experience changes in staffing with implications for patients. Objective: To examine hospital staffing and patient outcomes in emergency dep...
www.acpjournals.org
September 23, 2025 at 6:44 AM
Hardly a surprise!
Wow! A drug that is off patent and readily available. Excellent news!
September 11, 2025 at 7:56 AM
Wow! A drug that is off patent and readily available. Excellent news!
Reposted by Brigid Flanagan
#ResistanceEarth
#BlueEarth
Researchers have linked fine particulate air pollution (PM2.5) to the buildup of alpha-synuclein protein clumps called Lewy bodies. The clumps leads to neurodegenerative diseases, including Lewy body dementia and Parkinson's disease.
neurosciencenews.com/air-pollutio...
#BlueEarth
Researchers have linked fine particulate air pollution (PM2.5) to the buildup of alpha-synuclein protein clumps called Lewy bodies. The clumps leads to neurodegenerative diseases, including Lewy body dementia and Parkinson's disease.
neurosciencenews.com/air-pollutio...
Air Pollution Linked to Toxic Protein Clumps Driving Lewy Body Dementia - Neuroscience News
A new study reveals a molecular link between fine particulate air pollution (PM2.5) and Lewy body dementia, a devastating neurodegenerative condition.
neurosciencenews.com
September 7, 2025 at 10:24 PM
#ResistanceEarth
#BlueEarth
Researchers have linked fine particulate air pollution (PM2.5) to the buildup of alpha-synuclein protein clumps called Lewy bodies. The clumps leads to neurodegenerative diseases, including Lewy body dementia and Parkinson's disease.
neurosciencenews.com/air-pollutio...
#BlueEarth
Researchers have linked fine particulate air pollution (PM2.5) to the buildup of alpha-synuclein protein clumps called Lewy bodies. The clumps leads to neurodegenerative diseases, including Lewy body dementia and Parkinson's disease.
neurosciencenews.com/air-pollutio...
Hopefully the grant money is locked in and can't be rescinded!
Stem cell transplants — high risk procedures that replace a patient’s immune system with cells from a healthy donor — can cure HIV. Researchers at OHSU just won a 10-year grant to try to study this effect and design a better cure.
A handful of patients have been cured of HIV. OHSU just won $8.4 million to decode their cells for a cure
Researchers have known for more than a decade that the procedure will sometimes wipe out the HIV virus too — something scientists have been unable to do as in their hunt for a vaccine and a cure.
www.opb.org
August 29, 2025 at 5:12 PM
Hopefully the grant money is locked in and can't be rescinded!
Great win for Tommy Fleetwood...finally!
August 24, 2025 at 9:56 PM
Great win for Tommy Fleetwood...finally!
Good for them!
The Annals of Internal Medicine has refused US health secretary Robert F Kennedy Jr’s demand to retract a study that found that vaccines containing the adjuvant aluminium hydroxide did not increase the incidence of 50 chronic disorders, including autism and asthma
www.bmj.com/content/390/...
www.bmj.com/content/390/...
August 18, 2025 at 8:08 PM
Good for them!
Love this!
Patient’s potassium result was too low
Fired the lab manager
Fired the lab manager
August 3, 2025 at 9:03 AM
Love this!
Encouraging news for people with Parkinson's disease.
An early-stage clinical trial in France appeared to help restore some brain function for three Parkinson's patients.
Light stimulation shows promise in slowing Parkinson's, scientists say
An early-stage clinical trial in France appeared to help restore some brain function for three Parkinson's patients.
l.euronews.com
July 31, 2025 at 9:55 PM
Encouraging news for people with Parkinson's disease.
They don't make it easy to even get a copy of your consent!.
Remember that time when you had to sign a bunch of consent forms on a hospital iPad, with no idea what you are agreeing with? Digitizing paperwork could sometimes make it harder to opt out of data sharing or simply accessing your own records. themarkup.org/hello-world/...
During my kid’s surgery, I was denied a copy of my consent form — then sent to a ghost office – The Markup
Help us understand the challenges patients face opting out of voluntary uses of their data, or getting access to their records.
themarkup.org
July 31, 2025 at 6:55 PM
They don't make it easy to even get a copy of your consent!.
Some good news about Ivermectin ...not Covid related!
Ivermectin is an antiparasitic drug that kills mosquitoes feeding on treated persons. In this trial in Kenya, ivermectin given once per month for 3 months led to a 26% lower incidence of malaria than albendazole. Full trial results: nej.md/4lIyNzB
#MedSky #IDSky
#MedSky #IDSky
July 23, 2025 at 9:25 PM
Some good news about Ivermectin ...not Covid related!
Reposted by Brigid Flanagan
Lonni Besançon faced online abuse, threats and legal challenges in response to his research integrity sleuthing during the COVID-19 pandemic
go.nature.com/4m5DN0X
go.nature.com/4m5DN0X
The COVID-19 pandemic transformed this scientist into a research-integrity sleuth
Lonni Besançon has faced online abuse, threats and legal challenges. But he remains proud of his service to science and society.
go.nature.com
July 22, 2025 at 1:20 PM
Lonni Besançon faced online abuse, threats and legal challenges in response to his research integrity sleuthing during the COVID-19 pandemic
go.nature.com/4m5DN0X
go.nature.com/4m5DN0X
Worth watching. Hope for ALS patients.
July 16, 2025 at 8:13 AM
Worth watching. Hope for ALS patients.
Reposted by Brigid Flanagan
'We have someone practicing medicine without a license and people will be harmed'.
BREAKING: Six leading medical organizations filed a lawsuit on Monday against Robert F. Kennedy Jr., the health secretary, and the health dept, charging that recent decisions limiting access to vaccines were unscientific and harmful to the public.
(Gift link)
www.nytimes.com/2025/07/07/h...
(Gift link)
www.nytimes.com/2025/07/07/h...
Medical Societies Sue Kennedy and H.H.S. Over Vaccine Advice
www.nytimes.com
July 7, 2025 at 8:16 PM
'We have someone practicing medicine without a license and people will be harmed'.
Reposted by Brigid Flanagan
We're continuing to report on the impacts of the Trump administration canceling hundreds of grants supporting health research.
In our last story, we heard from more than 150 researchers. Many said these cuts would harm people participating in their studies:
In our last story, we heard from more than 150 researchers. Many said these cuts would harm people participating in their studies:
Shattered Science: The Research Lost as Trump Targets NIH Funding
The Trump administration cut research funding that sought cures for future pandemics, examined the causes of dementia and tried to prevent HIV transmission. More than 150 researchers shared with…
projects.propublica.org
July 3, 2025 at 2:01 PM
We're continuing to report on the impacts of the Trump administration canceling hundreds of grants supporting health research.
In our last story, we heard from more than 150 researchers. Many said these cuts would harm people participating in their studies:
In our last story, we heard from more than 150 researchers. Many said these cuts would harm people participating in their studies: