Ankur Sharma
@ankuroncofetal.bsky.social
Laboratory Head Garvan Institute | CSL Centenary Fellow | OncoFetal Ecosystem | #SingleCell #SpatialTranscriptomics #LiverCancer #Immunotherapy #Vaccines
Pinned
Ankur Sharma
@ankuroncofetal.bsky.social
· Feb 16
Garvan researchers will lead a project to map 2,000 cancer samples, aiming to understand why treatments vary across patients and cancer types. This initiative involves one of the largest collaborative cancer studies between Australia and Japan.
ow.ly/XPIF50UZTQe
ow.ly/XPIF50UZTQe
Very excited to launch CELLOGRAMRx a joint project between Australia 🇦🇺 (NHMRC) & Japan 🇯🇵 (AMED) teams to build a pan cancer atlas of oncofetal cells, understand population level differences and identify novel therapeutic targets by employing spatial omics & machine learning approaches!
This is game changer!!
Spatial multi-omics reveals cell-type-specific nuclear compartments
Two-layer DNA seqFISH+
Simultaneous mapping of 100,049 genomic loci
+ nascent transcriptome for 17,856 genes in single cells
www.nature.com/articles/s41...
Spatial multi-omics reveals cell-type-specific nuclear compartments
Two-layer DNA seqFISH+
Simultaneous mapping of 100,049 genomic loci
+ nascent transcriptome for 17,856 genes in single cells
www.nature.com/articles/s41...
April 10, 2025 at 10:03 PM
This is game changer!!
Spatial multi-omics reveals cell-type-specific nuclear compartments
Two-layer DNA seqFISH+
Simultaneous mapping of 100,049 genomic loci
+ nascent transcriptome for 17,856 genes in single cells
www.nature.com/articles/s41...
Spatial multi-omics reveals cell-type-specific nuclear compartments
Two-layer DNA seqFISH+
Simultaneous mapping of 100,049 genomic loci
+ nascent transcriptome for 17,856 genes in single cells
www.nature.com/articles/s41...
Reposted by Ankur Sharma
Run a lab at an international cancer research centre in Melbourne, Australia!
Applications open until May 9th….
👇👇👇
Applications open until May 9th….
👇👇👇
We are recruiting a group leader in laboratory research at Peter Mac Cancer Centre in
Melbourne, Australia 🔬🦘💥
Work in a cutting edge research environment in a vibrant world city!
We value research excellence, creativity and diversity.
Join us!
careers.petermac.org/job/MELBOURN...
Melbourne, Australia 🔬🦘💥
Work in a cutting edge research environment in a vibrant world city!
We value research excellence, creativity and diversity.
Join us!
careers.petermac.org/job/MELBOURN...
Group Leader
Group Leader
careers.petermac.org
March 21, 2025 at 9:09 PM
Run a lab at an international cancer research centre in Melbourne, Australia!
Applications open until May 9th….
👇👇👇
Applications open until May 9th….
👇👇👇
Reposted by Ankur Sharma
Bsky vs Twitter engagement difference now 50-fold...
March 11, 2025 at 4:18 PM
Bsky vs Twitter engagement difference now 50-fold...
Very excited to launch CELLOGRAMRx a joint project between Australia 🇦🇺 (NHMRC) & Japan 🇯🇵 (AMED) teams to build a pan cancer atlas of oncofetal cells, understand population level differences and identify novel therapeutic targets by employing spatial omics & machine learning approaches!
Garvan researchers will lead a project to map 2,000 cancer samples, aiming to understand why treatments vary across patients and cancer types. This initiative involves one of the largest collaborative cancer studies between Australia and Japan.
ow.ly/XPIF50UZTQe
ow.ly/XPIF50UZTQe
February 16, 2025 at 8:09 PM
Very excited to launch CELLOGRAMRx a joint project between Australia 🇦🇺 (NHMRC) & Japan 🇯🇵 (AMED) teams to build a pan cancer atlas of oncofetal cells, understand population level differences and identify novel therapeutic targets by employing spatial omics & machine learning approaches!
Reposted by Ankur Sharma
Fantastic opportunity: 🚀 Calling early-career scientists! Apply for the 2025 ELISIR Scholar at EPFL. From outstanding PhD straight to group leader. Join an interdisciplinary research community to conduct independent research in any area of #lifesciences in Lausanne, CH
👉 go.epfl.ch/ELISIR
👉 go.epfl.ch/ELISIR
EPFL Life Sciences Early Independent Research Scholar (ELISIR)
From exceptional PhD directly to independent group leader
go.epfl.ch
January 10, 2025 at 5:03 PM
Fantastic opportunity: 🚀 Calling early-career scientists! Apply for the 2025 ELISIR Scholar at EPFL. From outstanding PhD straight to group leader. Join an interdisciplinary research community to conduct independent research in any area of #lifesciences in Lausanne, CH
👉 go.epfl.ch/ELISIR
👉 go.epfl.ch/ELISIR
It was great to visit IIT-Kanpur and Delhi University his week and interact with colleagues Amit Dutt, Hamim Zafar, Arun Shukla, Ananda, Santosh and others.. discussing common grounds between developmental biology and cancer.. also an opportunity to revisit old memories of undergrad days..
January 9, 2025 at 3:36 AM
It was great to visit IIT-Kanpur and Delhi University his week and interact with colleagues Amit Dutt, Hamim Zafar, Arun Shukla, Ananda, Santosh and others.. discussing common grounds between developmental biology and cancer.. also an opportunity to revisit old memories of undergrad days..
Reposted by Ankur Sharma
We are here 🦋. Save the date for Oz Single Cell 2025, 23-25 May in Sydney
January 7, 2025 at 3:49 AM
We are here 🦋. Save the date for Oz Single Cell 2025, 23-25 May in Sydney
I’ll be speaking at DU south campus and talking about our recent work. Thank you Amit Dutt for kind invitation. This is an special for me as 20 years ago I did my first internship as undergraduate at DU Genetics dept which ignited my interest in genome biology 🧬
January 3, 2025 at 6:58 AM
I’ll be speaking at DU south campus and talking about our recent work. Thank you Amit Dutt for kind invitation. This is an special for me as 20 years ago I did my first internship as undergraduate at DU Genetics dept which ignited my interest in genome biology 🧬
Reposted by Ankur Sharma
Scientists can be classified as either Foxes or Hedgehogs; borrowing Isaiah Berlin’s famous use of the saying that “a fox knows many things, but a hedgehog knows one big thing”
Hedgehogs: Darwin, Monod, McClintock, Dawkins, Kimura..
Foxes: Wallace, Jacob, Brenner, Gould, Ohta..
Hedgehogs: Darwin, Monod, McClintock, Dawkins, Kimura..
Foxes: Wallace, Jacob, Brenner, Gould, Ohta..
December 22, 2024 at 2:32 AM
Scientists can be classified as either Foxes or Hedgehogs; borrowing Isaiah Berlin’s famous use of the saying that “a fox knows many things, but a hedgehog knows one big thing”
Hedgehogs: Darwin, Monod, McClintock, Dawkins, Kimura..
Foxes: Wallace, Jacob, Brenner, Gould, Ohta..
Hedgehogs: Darwin, Monod, McClintock, Dawkins, Kimura..
Foxes: Wallace, Jacob, Brenner, Gould, Ohta..
Reposted by Ankur Sharma
The fate of T cells, such as seen in exhausted T cells, is tied to nutrients. This introduces the potential of therapies directed at keeping T cell identity and function intact. (And the infamous Krebs cycle makes a comeback to my brain)
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Nutrient-driven histone code determines exhausted CD8+ T cell fates
ACLY-deficient CAR T cells targeting the tumor-associated antigen disialoganglioside GD2 (GD2 CAR T cells) also resisted acquiring TEX-like properties, exhibiting reduced CD39 expression when co-cultu...
www.science.org
December 12, 2024 at 10:36 PM
The fate of T cells, such as seen in exhausted T cells, is tied to nutrients. This introduces the potential of therapies directed at keeping T cell identity and function intact. (And the infamous Krebs cycle makes a comeback to my brain)
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Ankur Sharma
Find out more about Prof Cindy Ma @garvaninstitute.bsky.social & her journey @jexpmed.bsky.social. Cindy is in the Precision Immunology Program & will be our new Faculty Chair in 2025!
rupress.org/jem/article/...
rupress.org/jem/article/...
Cindy Ma: Science is often not black and white, and the answer usually lies in the grey | Journal of Experimental Medicine | Rockefeller University Press
Professor Cindy Ma heads the Human Immune Disorders Laboratory at the Garvan Institute of Medical Research. She is a member of the Garvan Faculty, holds a
rupress.org
December 6, 2024 at 8:55 PM
Find out more about Prof Cindy Ma @garvaninstitute.bsky.social & her journey @jexpmed.bsky.social. Cindy is in the Precision Immunology Program & will be our new Faculty Chair in 2025!
rupress.org/jem/article/...
rupress.org/jem/article/...
Reposted by Ankur Sharma
I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...
Method of the Year 2024: spatial proteomics - Nature Methods
Approaches for profiling the spatial proteome in tissues are the basis of atlas-scale projects that are delivering on their promise for understanding biological complexity in health and disease.
www.nature.com
December 6, 2024 at 8:52 PM
I could not be more thrilled to announce the Nature Methods @naturemethods.bsky.social Method of the Year is Spatial Proteomics! Please see our editorial as a roadmap to the fantastic content in this special issue! www.nature.com/articles/s41...
Reposted by Ankur Sharma
📢 World-leading Immunologists. The Nossal Endowed Chair of Immunology has just been announced @wehi-research.bsky.social. This is your chance to move (or return) to Australia to do ground-breaking research and join a thriving environment for discovery and translation.
WEHI - The Sir Gustav Nossal Professor of Immunology - Alumni Global
The Professor will lead transformative research into the complexities of the immune system, building on Sir Gustav Nossal’s pioneering work. By fostering a culture of scientific excellence and innovat...
alumniglobal.com
December 2, 2024 at 6:24 AM
📢 World-leading Immunologists. The Nossal Endowed Chair of Immunology has just been announced @wehi-research.bsky.social. This is your chance to move (or return) to Australia to do ground-breaking research and join a thriving environment for discovery and translation.
Reposted by Ankur Sharma
December 1, 2024 at 8:07 AM
Reposted by Ankur Sharma
If your #NHMRC ideas grant was unsuccessful and you have a story to share about the impact of this on your #biomedicalresearch, career, team - get in touch. Federal DOH have asked #NARF to collect stories of impact of low funding. #SaveOzScience #DiscoveriesNeedDollars #EMCRs
November 26, 2024 at 1:46 AM
If your #NHMRC ideas grant was unsuccessful and you have a story to share about the impact of this on your #biomedicalresearch, career, team - get in touch. Federal DOH have asked #NARF to collect stories of impact of low funding. #SaveOzScience #DiscoveriesNeedDollars #EMCRs
Reposted by Ankur Sharma
At Garvan, we see a future where everyone lives a longer, healthier life.
We bring together world-leading researchers and clinicians, collaborating locally and globally, to improve human health.
www.youtube.com/watch?v=FOIP...
#science #medicalresearch #health #disease
We bring together world-leading researchers and clinicians, collaborating locally and globally, to improve human health.
www.youtube.com/watch?v=FOIP...
#science #medicalresearch #health #disease
Welcome to Garvan
YouTube video by Garvan Institute of Medical Research
www.youtube.com
November 25, 2024 at 12:33 AM
At Garvan, we see a future where everyone lives a longer, healthier life.
We bring together world-leading researchers and clinicians, collaborating locally and globally, to improve human health.
www.youtube.com/watch?v=FOIP...
#science #medicalresearch #health #disease
We bring together world-leading researchers and clinicians, collaborating locally and globally, to improve human health.
www.youtube.com/watch?v=FOIP...
#science #medicalresearch #health #disease
Reposted by Ankur Sharma
November 23, 2024 at 7:45 PM
Reposted by Ankur Sharma
‘A place of joy’: why scientists are joining the rush to Bluesky
For me, it certainly feels good to be here!
@natureportfolio.bsky.social @bsky.app
www.nature.com/articles/d41...
For me, it certainly feels good to be here!
@natureportfolio.bsky.social @bsky.app
www.nature.com/articles/d41...
‘A place of joy’: why scientists are joining the rush to Bluesky
Researchers say the social-media platform — an alternative to X — offers more control over the content they see and the people they engage with.
www.nature.com
November 22, 2024 at 6:49 AM
‘A place of joy’: why scientists are joining the rush to Bluesky
For me, it certainly feels good to be here!
@natureportfolio.bsky.social @bsky.app
www.nature.com/articles/d41...
For me, it certainly feels good to be here!
@natureportfolio.bsky.social @bsky.app
www.nature.com/articles/d41...
Five months into new gig! Here we are building world class team in Oncofetal research at Garvan Institute! We are looking for a computational biologist with proven track record in spatial biology, if you are keen to explore neighbourhoods drop a text :)
November 22, 2024 at 9:26 AM
Five months into new gig! Here we are building world class team in Oncofetal research at Garvan Institute! We are looking for a computational biologist with proven track record in spatial biology, if you are keen to explore neighbourhoods drop a text :)
@jleslie1.bsky.social welcome mate!
November 22, 2024 at 8:05 AM
@jleslie1.bsky.social welcome mate!
Reposted by Ankur Sharma
We have a new position for a bioinformatician / computational biologist exploring genomic and epigenomic features of #cfDNA to uncover new cancer biology.
careers.petermac.org/job/MELBOURN...
careers.petermac.org/job/MELBOURN...
Bioinformatics Post Doctoral Researcher - SJ Dawson
Bioinformatics Post Doctoral Researcher - SJ Dawson
careers.petermac.org
November 21, 2024 at 6:45 AM
We have a new position for a bioinformatician / computational biologist exploring genomic and epigenomic features of #cfDNA to uncover new cancer biology.
careers.petermac.org/job/MELBOURN...
careers.petermac.org/job/MELBOURN...
Art of doing night science by Keith Yamamoto
1. Ability to identify important problems
2. Develop hypothesis
3. Capacity to jigsaw puzzle
4. Taking a risky route
#justdoit
youtube.com/watch?v=3-aH...
1. Ability to identify important problems
2. Develop hypothesis
3. Capacity to jigsaw puzzle
4. Taking a risky route
#justdoit
youtube.com/watch?v=3-aH...
youtube.com
November 21, 2024 at 8:31 PM
Art of doing night science by Keith Yamamoto
1. Ability to identify important problems
2. Develop hypothesis
3. Capacity to jigsaw puzzle
4. Taking a risky route
#justdoit
youtube.com/watch?v=3-aH...
1. Ability to identify important problems
2. Develop hypothesis
3. Capacity to jigsaw puzzle
4. Taking a risky route
#justdoit
youtube.com/watch?v=3-aH...
Reposted by Ankur Sharma
CHMC Division of Immunobiology is hiring Assistant Professors. You can have a lab next to mine if you like.
November 20, 2024 at 7:33 PM
CHMC Division of Immunobiology is hiring Assistant Professors. You can have a lab next to mine if you like.
Very cool work on Notch signaling’s role in drives sexually dimorphic responses in HCC by @amaialujambio.bsky.social & co. in Cancer Discovery
aacrjournals.org/cancerdiscov...
aacrjournals.org/cancerdiscov...
November 20, 2024 at 8:16 PM
Very cool work on Notch signaling’s role in drives sexually dimorphic responses in HCC by @amaialujambio.bsky.social & co. in Cancer Discovery
aacrjournals.org/cancerdiscov...
aacrjournals.org/cancerdiscov...
Reposted by Ankur Sharma
Pls share 🌟Join the IMP as a Group Leader
We are 👀 for a colleague, ready to lead a groundbreaking research program. Enjoy generous funding, outstanding facilities & a vibrant scientific community in one of the world's most livable cities @impvienna.bsky.social
👉https://tinyurl.com/impgl2025
November 20, 2024 at 10:46 AM
Pls share 🌟Join the IMP as a Group Leader
We are 👀 for a colleague, ready to lead a groundbreaking research program. Enjoy generous funding, outstanding facilities & a vibrant scientific community in one of the world's most livable cities @impvienna.bsky.social
👉https://tinyurl.com/impgl2025