Umberto Perron
@uperron.bsky.social
🧪🤖 #Bioinformatics + #CompBio + #ML for #immunology at omniscope.ai //
📍🇪🇺🇮🇹🇪🇸 //
🧶 protein enjoyer //
🔧 I try to fix stuff //
📍🇪🇺🇮🇹🇪🇸 //
🧶 protein enjoyer //
🔧 I try to fix stuff //
Pinned
Umberto Perron
@uperron.bsky.social
· Nov 17
Any chance of getting Biology+AI Daily in here? Biggest X pull factor left for me tbh
Reposted by Umberto Perron
17-year-long Scottish study of 82,000+ adults finds commuting by bike reduces your risk of:
• early death
• hospitalisation for any reason
• cardiovascular disease
• cancer mortality
• treatment for mental health problems.
Yeah, but those LTNs and bike lanes are *really* annoying.
• early death
• hospitalisation for any reason
• cardiovascular disease
• cancer mortality
• treatment for mental health problems.
Yeah, but those LTNs and bike lanes are *really* annoying.
December 18, 2024 at 10:36 AM
17-year-long Scottish study of 82,000+ adults finds commuting by bike reduces your risk of:
• early death
• hospitalisation for any reason
• cardiovascular disease
• cancer mortality
• treatment for mental health problems.
Yeah, but those LTNs and bike lanes are *really* annoying.
• early death
• hospitalisation for any reason
• cardiovascular disease
• cancer mortality
• treatment for mental health problems.
Yeah, but those LTNs and bike lanes are *really* annoying.
Reposted by Umberto Perron
Three must read papers for PhD students. #scisky #PhD #science #research #academicsky
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
November 24, 2024 at 1:54 PM
Three must read papers for PhD students. #scisky #PhD #science #research #academicsky
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
1. The importance of stupidity in scientific research
Open Access
journals.biologists.com/jcs/article/...
Reposted by Umberto Perron
Immunotherapy for oncology
New more effective & cheap anti-venoms
Allosteric switch proteins
New Alzheimer’s treatments
De novo functional nanopores
Vaccines
And so much more from Baker Lab. Thank you for being such an inspiration and for forging a path forward. 🚀💜
www.youtube.com/live/HnT1VWz...
New more effective & cheap anti-venoms
Allosteric switch proteins
New Alzheimer’s treatments
De novo functional nanopores
Vaccines
And so much more from Baker Lab. Thank you for being such an inspiration and for forging a path forward. 🚀💜
www.youtube.com/live/HnT1VWz...
YouTube
Share your videos with friends, family, and the world
www.youtube.com
December 9, 2024 at 8:43 PM
Immunotherapy for oncology
New more effective & cheap anti-venoms
Allosteric switch proteins
New Alzheimer’s treatments
De novo functional nanopores
Vaccines
And so much more from Baker Lab. Thank you for being such an inspiration and for forging a path forward. 🚀💜
www.youtube.com/live/HnT1VWz...
New more effective & cheap anti-venoms
Allosteric switch proteins
New Alzheimer’s treatments
De novo functional nanopores
Vaccines
And so much more from Baker Lab. Thank you for being such an inspiration and for forging a path forward. 🚀💜
www.youtube.com/live/HnT1VWz...
Reposted by Umberto Perron
We updated our BindCraft preprint with lots of new exciting results! We release all our binder sequences and models, include more in silico analysis, novel design targets, and present AAV retargeting to specific cell types using de novo binders!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 8, 2024 at 8:27 AM
We updated our BindCraft preprint with lots of new exciting results! We release all our binder sequences and models, include more in silico analysis, novel design targets, and present AAV retargeting to specific cell types using de novo binders!
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Umberto Perron
Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
December 6, 2024 at 8:39 AM
Super excited to preprint our work on developing a Biomolecular Emulator (BioEmu): Scalable emulation of protein equilibrium ensembles with generative deep learning from @msftresearch.bsky.social ch AI for Science.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Umberto Perron
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
There are already many articles for which there is more attention on Bluesky than on other comparable micro-blogging sites, meaning the academic community and the general public have clearly adopted Bluesky as one of its core places to disseminate and discuss new research.
A Place of Joy.
A Place of Joy.
December 3, 2024 at 2:10 PM
Scientists, academics, researchers: We’re excited to share that @altmetric.com is now tracking mentions of your research on Bluesky! 🧪
Reposted by Umberto Perron
Strong new evidence for T cell exhaustion in myalgic encephalomyelitis (ME/CFS) reflecting chronic viral infection, relevant to #LongCovid, and possible path to treatment candidates
www.pnas.org/doi/epub/10.... @pnas.org
www.pnas.org/doi/epub/10.... @pnas.org
December 2, 2024 at 8:46 PM
Strong new evidence for T cell exhaustion in myalgic encephalomyelitis (ME/CFS) reflecting chronic viral infection, relevant to #LongCovid, and possible path to treatment candidates
www.pnas.org/doi/epub/10.... @pnas.org
www.pnas.org/doi/epub/10.... @pnas.org
Reposted by Umberto Perron
#ExperimentRequest does anyone have room in their budget to A) retrain MPNN exclusively on cold-adapted proteins and B) express some designs and measure their thermostability?
n=1, but IMO the most important result in this paper is the negative result that this training set does no better on designing proteins with high melting temperatures
December 3, 2024 at 9:35 AM
#ExperimentRequest does anyone have room in their budget to A) retrain MPNN exclusively on cold-adapted proteins and B) express some designs and measure their thermostability?
btw that staircase isn't Midjourney hallucinating, it's actually a real place @embl.org 🧬
Join EMBL’s scientific community 🙌
Apply until 31 December:
👉 EMBL CPP fellowship www.embl.org/about/info/s...
👉 EMBL Sabbatical Visitor fellowship
www.embl.org/about/info/s...
We can’t wait to see you around!
🧪🧬 🔬 🖥️ #MolBiol
Apply until 31 December:
👉 EMBL CPP fellowship www.embl.org/about/info/s...
👉 EMBL Sabbatical Visitor fellowship
www.embl.org/about/info/s...
We can’t wait to see you around!
🧪🧬 🔬 🖥️ #MolBiol
November 25, 2024 at 9:18 AM
btw that staircase isn't Midjourney hallucinating, it's actually a real place @embl.org 🧬
so sick!
Hey folks! I got a tattoo of my beloved PIEZO ion channel on my arm! Now I can show how they activate (flatten) under pressure by flexing—Will add a bit of performance art to my science talks 🧪🧠.
November 22, 2024 at 10:27 AM
so sick!
Reposted by Umberto Perron
Now I can share external links without the posts being down regulated - I thought it would share this again!:)
I have compiled a list of now 100+ companies in the 'TechBio' space into a fully open database for the community.
Find here and please share if you like
open.substack.com/pub/harrisbi...
I have compiled a list of now 100+ companies in the 'TechBio' space into a fully open database for the community.
Find here and please share if you like
open.substack.com/pub/harrisbi...
November 21, 2024 at 8:53 AM
Now I can share external links without the posts being down regulated - I thought it would share this again!:)
I have compiled a list of now 100+ companies in the 'TechBio' space into a fully open database for the community.
Find here and please share if you like
open.substack.com/pub/harrisbi...
I have compiled a list of now 100+ companies in the 'TechBio' space into a fully open database for the community.
Find here and please share if you like
open.substack.com/pub/harrisbi...
The sky is blue over the south building @ebi.embl.org 💙
Not enough bioinformatics in your Bluesky feed? We’ve got you covered. Follow us for our latest news, exciting life science research, updates from our data resources, new tools and training resources.
Haven't heard of EMBL-EBI? Take a look at what we’re working on. www.ebi.ac.uk/about/our-im...
Haven't heard of EMBL-EBI? Take a look at what we’re working on. www.ebi.ac.uk/about/our-im...
Our impact
We provide open data that helps scientists understand life and that informs solutions to real-world problems, such as infectious diseases, climate change and food security.
www.ebi.ac.uk
November 20, 2024 at 9:51 AM
The sky is blue over the south building @ebi.embl.org 💙
Reposted by Umberto Perron
There’s a new Practical Cheminformatics post, “Some Thoughts on Dataset Splitting,” (with code and a robot cartoon) at practicalcheminformatics.blogspot.com/2024/11/some... .
November 18, 2024 at 1:34 PM
There’s a new Practical Cheminformatics post, “Some Thoughts on Dataset Splitting,” (with code and a robot cartoon) at practicalcheminformatics.blogspot.com/2024/11/some... .
The classics are back
November 18, 2024 at 7:05 PM
The classics are back
Any chance of getting Biology+AI Daily in here? Biggest X pull factor left for me tbh
November 17, 2024 at 7:32 PM
Any chance of getting Biology+AI Daily in here? Biggest X pull factor left for me tbh
Great stuff! Can't wait to try this out (yay MIT) 🤓
Thrilled to announce Boltz-1, the first open-source and commercially available model to achieve AlphaFold3-level accuracy on biomolecular structure prediction! An exciting collaboration with Jeremy, Saro, and an amazing team at MIT and Genesis Therapeutics. A thread!
November 17, 2024 at 6:57 PM
Great stuff! Can't wait to try this out (yay MIT) 🤓
Reposted by Umberto Perron
who knew it would be easier to get everyone to switch social media platforms than getting them to use hg38
November 14, 2024 at 6:45 PM
who knew it would be easier to get everyone to switch social media platforms than getting them to use hg38