Dr Satoshi Akima, FRACP
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toshiakima.bsky.social
Dr Satoshi Akima, FRACP
@toshiakima.bsky.social
12K followers 1.9K following 940 posts
Nephrology & Internal Medicine. Immunothrombosis incl DIC. ISTH Member. No Conflicts of Interest. Views my own etc
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toshiakima.bsky.social
Dr Satoshi Akima, FRACP @toshiakima.bsky.social · Nov 4
The Central Error of the Pandemic…

Is that of running pandemic management by laissez-faire socioeconomic principles.

If you grasp this, all the other errors fall into place as the inevitable consequence of following that line of thought. 🧵 1/x
Reposted by Dr Satoshi Akima, FRACP
thjournal.bsky.social
📣 Heavy Menstrual Bleeding in Women Treated with DOACs: Results of the HEMBLED Registry ⬇️

📌 Lindhoff-Last report differences among DOACs and their influence on the intensity of sponteneous menstrual bleeding

🆓 on TH: www.thieme-connect.de/products/ejo...

#Thrombosis #DOAC #VTE #HemeSky
November 21, 2025 at 7:31 PM
Reposted by Dr Satoshi Akima, FRACP
jama.com
Adults with #AFib who drank at least one cup of caffeinated coffee daily after successful cardioversion had a lower risk of recurrence than those who abstained from coffee & caffeine.

Lead author & JAMA Associate Editor Gregory M. Marcus, MD, MAS, explains the results of the study.

🔗 ja.ma/4p14pSw
November 25, 2025 at 2:25 PM
toshiakima.bsky.social
TGA says some vitamin B6 will come off shelves and require prescriptions for large doses after rise in toxicity cases apple.news/A_FmyXxPATFC...
B6 toxicity victims 'vindicated' as TGA confirms it is coming off shelves — ABC News
The Therapeutic Goods Administration (TGA) will crack down on vitamin B6 after a rise in toxicity cases causing life-altering nerve damage to many Australians.
apple.news
November 25, 2025 at 8:22 PM
Reposted by Dr Satoshi Akima, FRACP
panaccindex.bsky.social
cholera in Hamburg, 1892 broke me www.panaccindex.info/p/review-dea...
REVIEW: Death in Hamburg: Society and Politics in the Cholera Years by Richard J. Evans (1987)
The Legacy of Johann Kraus Lives On
www.panaccindex.info
November 25, 2025 at 7:17 PM
Reposted by Dr Satoshi Akima, FRACP
mikehoney.bsky.social
My work on SARS-CoV-2 variants informed a recent piece in The Lancet: "Epidemiological and virological update on the emerging SARS-CoV-2 variant BA.3.2".

The authors were kind enough to mention me and the Variant Hunters Ryan Hisner and Federico Gueli.
www.thelancet.com/journals/lan...
🧵
Epidemiological and virological update on the emerging SARS-CoV-2 variant BA.3.2
The constant emergence of novel SARS-CoV-2 variants has driven the COVID-19 pandemic and sustains the current endemic. Saltation variants, such as BA.2.86,1 encode highly mutated spike (S) proteins th...
www.thelancet.com
November 25, 2025 at 1:30 AM
Reposted by Dr Satoshi Akima, FRACP
njbbari3.bsky.social
I think… if there was ever a good reason to burn jet fuel… raising awareness and interest in preventing airborne disease in hospitals among people for whom it is a constant workplace hazard has to be one.

I’m very pleased with how enthusiastic clinicians have been on #SaferAirInHealthcare
November 25, 2025 at 11:20 AM
Reposted by Dr Satoshi Akima, FRACP
mikehoney.bsky.social
Australian COVID-19 weekly stats update:

The risk estimate has been inching up again, current around 0.1% “Currently Infectious”, or 1-in-758.

That implies a 4% chance that someone is infectious in a group of 30.

#COVID19 #SARSCoV2 #Australia
🧵
November 24, 2025 at 9:45 AM
Reposted by Dr Satoshi Akima, FRACP
buonsenso.bsky.social
Low-Dose Rapamycin for ME/CFS and Long COVID: New Clinical Data, Promising Hints, and Ongoing Caution

danilobuonsenso.substack.com/p/low-dose-r...
Low-Dose Rapamycin for ME/CFS and Long COVID: New Clinical Data, Promising Hints, and Ongoing Caution
Over the past months, I have written several posts exploring the potential role of low-dose rapamycin in Long COVID and ME/CFS (Part 1, Part 2, Part 3).
danilobuonsenso.substack.com
November 23, 2025 at 3:25 PM
Reposted by Dr Satoshi Akima, FRACP
nejm.org
In patients with cardiovascular disease and an implantable cardioverter–defibrillator, increasing potassium levels to the high-normal range reduced the risk of arrhythmia events, hospitalizations, and death. Full POTCAST trial results: nej.md/4oQtHTN

#MedSky #CardioSky
November 23, 2025 at 8:01 PM
Reposted by Dr Satoshi Akima, FRACP
mikehoney.bsky.social
Here's the latest variant picture with a global scope, to early November.

BA.3.* (mostly BA.3.2.2) has started showing significant signs of growth. Recent samples have mostly been reported from Germany and Australia.

#COVID19 #SARSCoV2 #Global #BA_3_2 #XFG #Stratus
🧵
November 23, 2025 at 5:28 AM
Reposted by Dr Satoshi Akima, FRACP
mikehoney.bsky.social
Here's the latest variant picture for Australia, to early November.

BA.3.* (all BA.3.2.2) rose to 19% and seems the most likely challenger to replace NB.1.8.1.* "Nimbus".

#COVID19 #SARSCoV2 #Australia #BA_3_2
🧵
November 23, 2025 at 5:42 AM
Reposted by Dr Satoshi Akima, FRACP
njbbari3.bsky.social
Wear a #respie *before*, during and after your “winter bug”… because there are lots of them, and the next one is waiting.

www.manchestereveningnews.co.uk/news/uk-news...
UKHSA says 'wear a mask' as four viruses spread in UK
Health bosses expect to see 'further increases' in winter virus levels as the colder months hit
www.manchestereveningnews.co.uk
November 23, 2025 at 2:46 AM
Reposted by Dr Satoshi Akima, FRACP
toshiakima.bsky.social
Overall, this review highlights the limited evidence supporting the use of anti-Xa monitoring for dose adjustments in the therapeutic use of low-molecular-weight heparins. Therefore, we conclude that measuring anti-Xa levels is currently not justified. @jthjournal.bsky.social
A systematic review on anti-Xa monitoring in the therapeutic use of low-molecular-weight heparins - PubMed
Low-molecular-weight heparins are widely utilized, including in special patient populations (eg, patients with renal impairment, pregnancy, and obesity). Monitoring with anti-Xa measurements is often used, but the effectiveness of anti-Xa-based dose adjustments remains uncertain. This systematic rev …
pubmed.ncbi.nlm.nih.gov
November 21, 2025 at 11:28 PM
Reposted by Dr Satoshi Akima, FRACP
thecovidinfoguy.bsky.social
AUSTRALIA Weekly COVID Update — 21 November 2025

SA up (+24.8%)
NSW up (+6.3%)

WA down (-9.3%) Avg 17/day in hospital
QLD down (-2.0%) 29 in hospital (+38%)

VIC next update: 28 Nov
TAS next update: 12 Dec

ACT paused reporting for 2025

Aged-care update delayed today
A table titled “AUSTRALIA Weekly COVID Update — 21 November 2025.” It lists each state and territory with columns for Trend, % Change, and Reporting Notes. SA: UP +24.8%, weekly update. NSW: UP +6.3%, weekly update; positivity 2.5%. WA: DOWN –9.3%, 17 in hospital per day; positivity 2.1%. QLD: DOWN –2.0%, 29 in hospital (+38%). VIC: No data; fortnightly reporting, next update 28 Nov. TAS: No data; monthly reporting, next update 12 Dec. ACT: Ended weekly reporting for 2025; returns autumn/winter 2026. NT: COVID data no longer published on NT Health’s website. Aged care: Weekly data delayed; not published today.
November 21, 2025 at 7:23 AM
Reposted by Dr Satoshi Akima, FRACP
thecovidinfoguy.bsky.social
Economic burden of long COVID: macroeconomic, cost-of-illness and microeconomic impacts

Published: 21 November 2025

Long COVID affects an estimated 36% globally, creating a huge economic burden: about $1 trillion a year worldwide, roughly $9,000 per US patient and $170 billion in lost US earnings.
A screenshot of an article page from npj Primary Care Respiratory Medicine. The headline reads: “Economic burden of long COVID: macroeconomic, cost-of-illness and microeconomic impacts.” The article is written by Amit Bansal and published on 21 November 2025 as an open-access brief communication. The abstract text explains that Long COVID—defined as symptoms lasting more than three months after SARS-CoV-2 infection—poses a major global health and economic challenge. It notes a global prevalence estimate of 36%, with reported ranges from 1–92%. The article summarizes current estimates of economic impacts, including macroeconomic costs, cost-of-illness, and microeconomic effects. It highlights an average annual global economic burden of $1 trillion and about $9,000 per patient in the USA, where some individuals also face substantial out-of-pocket costs. Lost earnings in the USA are estimated at $170 billion annually. The abstract further mentions increased unemployment, financial distress, and work impairment lasting up to three years post-infection. The paper calls for standardised metrics, notes methodological discrepancies, and identifies research gaps, including the lack of longitudinal studies, limited economic aggregation, and insufficient data on long COVID subtypes, biomarkers, and intervention evaluations.
November 22, 2025 at 1:51 AM
Reposted by Dr Satoshi Akima, FRACP
elisaperego78.bsky.social
Autopsies of 18 foetuses showed that "SARS-CoV-2 can be widely distributed in fetal organs through vertical transmission". In addition immune and DNA damage were found in the infected organs

www.nature.com/articles/s41...
Presence of SARS-CoV-2 in fetal organs via intraamniotic infection - Nature Communications
Infection with SARS-CoV-2 during pregnancy may result in maternal and fetal complications. Here, the authors analyze 18 fetuses following maternal SARS-CoV-2 infection and identify distribution in fet...
www.nature.com
November 22, 2025 at 1:12 AM
Reposted by Dr Satoshi Akima, FRACP
pedshemedoc.bsky.social
Vaccines DO NOT cause autism - there is extensive research showing this. Resurrecting old, discredited, fraudulent work is shameful.

Vaccine-preventable illnesses are serious - this is going to cause real harms.

This is dangerous & disappointing.
November 21, 2025 at 11:40 PM
toshiakima.bsky.social
Debunking the myth of so-called “corrected” calcium. Use whole/uncorrected Ca as your screening test and confirm with an ionised Ca
November 22, 2025 at 12:11 AM
toshiakima.bsky.social
Overall, this review highlights the limited evidence supporting the use of anti-Xa monitoring for dose adjustments in the therapeutic use of low-molecular-weight heparins. Therefore, we conclude that measuring anti-Xa levels is currently not justified. @jthjournal.bsky.social
A systematic review on anti-Xa monitoring in the therapeutic use of low-molecular-weight heparins - PubMed
Low-molecular-weight heparins are widely utilized, including in special patient populations (eg, patients with renal impairment, pregnancy, and obesity). Monitoring with anti-Xa measurements is often used, but the effectiveness of anti-Xa-based dose adjustments remains uncertain. This systematic rev …
pubmed.ncbi.nlm.nih.gov
November 21, 2025 at 11:28 PM
Reposted by Dr Satoshi Akima, FRACP
thecovidinfoguy.bsky.social
Japan’s flu cases are rising at the fastest pace in 10 years, with experts pointing to the rising number of tourists as one of the likely factors.

From Nov 10–16, 145,526 cases were reported across 3,000 facilities, averaging 37.7—above the 30 warning level.

Source: archive.md/tGnSi
A news page from The Straits Times shows the headline: “Japan’s flu cases hit warning level at fastest pace in 10 years.” Below the headline is a photo of a busy street in Japan with several people walking outdoors. The street is lined with tall buildings covered in colorful shop signs and advertisements, including signs for ABC Mart and various restaurants. The lighting suggests late afternoon, with shadows cast across the walkway. The people in the foreground appear dressed for cool weather, wearing jackets and long sleeves. The caption notes that the most commonly reported virus was the type-A Hong Kong strain. The article lists its publication and update time as November 21, 2025.
November 21, 2025 at 11:01 PM
Reposted by Dr Satoshi Akima, FRACP
njbbari3.bsky.social
And look at this… flu and the heart… 1930s!

virologyresearchservices.com/2019/04/30/w....
When Flu hits you in the Heart - VIROLOGY RESEARCH SERVICES
Why you’re at increased risk of heart attack when you have the flu
virologyresearchservices.com
November 19, 2025 at 9:06 PM
Reposted by Dr Satoshi Akima, FRACP
thecovidinfoguy.bsky.social
Princess Kako of Japan tested positive for COVID-19 after developing a fever on Tuesday. She had a sore throat Sunday after a Tokyo event and tested negative Monday, but a second test on Tuesday returned a positive result.

Source: archive.md/IAquh
A news article from Nippon.com titled “Japanese Princess Kako Tests Positive for COVID-19.” Below the headline is a photo of Princess Kako standing at a podium, holding papers and speaking into two microphones. She wears a white floral blouse with a black bow and looks composed against a plain yellow backdrop.
November 18, 2025 at 6:11 AM
Reposted by Dr Satoshi Akima, FRACP
thecovidinfoguy.bsky.social
UK: "Two-thirds of nurses in UK work while unwell, says union"

"A survey by the Royal College of Nursing (RCN) of more than 20,000 nursing staff found that 66% had worked when they should have been on sick leave, up from 49% in 2017."

www.theguardian.com/society/2025...
Two-thirds of nurses in UK work while unwell, says union
Understaffing is driving workers to ill health and discouraging them for taking leave, says Royal College of Nursing CEO
www.theguardian.com
November 18, 2025 at 3:45 AM
Reposted by Dr Satoshi Akima, FRACP
healthcare-global.bsky.social
www.sciencedaily.com/releases/202...
CRISPR brings back ancient gene that prevents gout and fatty liver
By reactivating a long-lost gene, researchers were able to lower uric acid levels and stop damaging fat accumulation in human liver models. The breakthrough hints at a future where gout and several me...
www.sciencedaily.com
November 17, 2025 at 1:56 AM
Reposted by Dr Satoshi Akima, FRACP
adamjkucharski.bsky.social
NIH directors have pointed to below estimates as evidence that Sweden was 'best in the world at protecting human life' for COVID (www.city-journal.org/article/nih-...). But plot doesn't show what they apparently think it shows - and there is a big red flag that immediately jumps out... 🧵
November 16, 2025 at 10:02 AM