Marc Perry
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mdperry.bsky.social
Marc Perry
@mdperry.bsky.social
700 followers 1.8K following 110 posts
Biochemist (by training), Geneticist (by osmosis), Bioinformatician (by experience). Possesses an extremely peculiar sense of humor/humour.
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Reposted by Marc Perry
A potent and plain-spoken defence of DEI in science - from the experts. Representation *matters*.
(Voice of Mr. Rogers) “Can you say Nosferatu? Sure you can(!)” #twilight
Well obvs he is one hot MAGA warrior [this is sarcasm]. Facts: he is (a) overly full of himself, (b) delusional, (c) a Josef Goebbels doppelgänger, (AND wannabe). I don’t think he’ll be happy until he incites an armed revolt and then gets to call in air strikes on tenement slums. (IMHO)
Reposted by Marc Perry
John Clarke, Michel Devoret and John Martinis have been awarded the 2025 Nobel Prize in Physics for demonstrating quantum physics on the macroscopic scale, which has paved the way for quantum computing. ⚛️🧪
Groundbreaking quantum-tunnelling experiments win physics Nobel
John Clarke, Michel Devoret and John Martinis discovered quantum physics on a macroscopic scale, paving the way for quantum computing.
go.nature.com
Today’s NYT Spelling Bee Puzzle seems replete with answers for a former #celegans #genetics fan . . .
Reposted by Marc Perry
Are you an early career scientist who wants to get specialist training in C. elegans model for your laboratory research? we co-organize again the EMBO C. elegans course! Do not miss applying!
🪱 Ready to take your C. elegans skills to the next level? Join our #EMBOCelegans course!

🎯 Learn hands-on genome editing, AI-driven imaging, microfluidics & uncover development, physiology & evolutionary insights.

📍 EMBL Heidelberg
📅 23 – 29 Mar 2026
👉 Apply by 8 Dec: s.embl.org/cel26-01-bl
Reposted by Marc Perry
Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans

journals.biologists.com/dev/article/...
Reposted by Marc Perry
Fun fact: diluted tattoo inks and washes make pretty decent carbon sources for NTMs.
Reposted by Marc Perry
You had me at "supergiant cannibals." 😱 Gotta love the world of ciliates. Good🧵⬇️
As a member of the Toronto Perl Mongers I volunteered at the TPRC held in Toronto in 2023. This blog post from Bryan Katz relates his experience with Perl in general, and specifically at that conference #relatable #perl
www.perl.com/article/my-g...
My Guilty Perl Obsession
Perl came for free. How much have I contributed in return? Absolutely nothing.
www.perl.com
Roundworms = nematodes
Flatworms = platyhelminths
Segmented worms = annelids
Have they changed this system of classifying types of worms since the late 1970s (when I learned it/them)?
Next you’ll be telling us Pluto is no longer a planet and that birds are just a type of reptile.
Reposted by Marc Perry
Pervasive homeobox gene function in the male-specific nervous system of Caenorhabditis elegans https://www.biorxiv.org/content/10.1101/2025.05.13.653874v1
Whoah!!
I am pleased to share our latest manuscript, a collaboration with my @sickkidsto.bsky.socical colleague Dr. Ran Kafri. Led by PhD student Rachel Webster, who found that the CDK4/Rb/E2F pathway regulates metabolism to prevent premature aging in C. elegans. www.nature.com/articles/s41...
CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans - Heredity
Heredity - CDK-4 regulates nucleolar size and metabolism at the cost of late-life fitness in C. elegans
www.nature.com
Reposted by Marc Perry
The Provisional Mortality statistics have been updated by the Australian Bureau of Statistics (ABS), up to January 2025.

Here are the deaths where the underlying cause of death was certified by a doctor as COVID-19 (22,357 deaths).
#COVID19 #Australia
🧵
Reposted by Marc Perry
The US has cut the equivalent of 3X the total annual CIHR budget so far this year, revealing both how low the CIHR budget is and how utterly draconian the White House has treated one of the most precious and successful institutions the US has ever built.
Update of my analysis of funding missing in FY2025 compared to FY2024.

Bottom line: The missing amount is estimated to be $2.05 B from non-competitive renewals and $0.83 B from new and competitive renewals.

Total: $2.88 B
Reposted by Marc Perry
Huge thanks to Federico Gueli for his tips on new lineages to watch out for, eg
bsky.app/profile/siam...
🧵
One SC2 variant that i see usually overlooked is XFC that is basically LP.8.1.1 with the NTD from LF.7 ,
interestingly it has been sampled two times in travelers coming into US from Ethiopia in a period spanning four months suggesting it may have high prevalence there along with XFJ .
Reposted by Marc Perry
With the LP.8.1.* variant dominant from the global perspective, it is time to ponder which variant might drive the next wave.

The leading contenders at this point are XDV.* (led by NB.1.8.1), and XFG.*.
#COVID19 #NB_1_8_1 #XFG
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@augustorendon.bsky.social It was such a good idea now everyone is copying you. Who knew?
🇨🇦 Canada is sequencing 100,000 genomes to revolutionize healthcare. From rare diseases to drug safety in kids, this $200M effort will drive AI-powered precision health—and ensure breakthroughs reflect Canada’s diverse population. It's our turn. #Genomics genomecanada.ca/how-100000-g...
How 100,000 Genomes Can Help Re-define Health Care in Canada - GenomeCanada
What if your doctor could really see you? Not just the physical you, but the genetic you? Genetic variation causes cancer, rare disease and hereditary illness. It can be linked to drastically differe...
genomecanada.ca
Oh the stories we could uncover if we collected all of these tales. As a postdoc we learned that Bob Horvitz selected ‘n’ b/c he tested all of the remaining single letters and n was the easiest/fastest to draw. Who knows? I used ‘uc’ for (pick 1): Upper Canada|Univ of California|Univ of Colorado
Reposted by Marc Perry
🪱 Worm people! C. elegans Mentor Match sign-ups close May 8:

👩‍🔬 Be matched with a mentor → custom career guidance
🤝 Join a peer group → swap tips & stay accountable
✨ Both → double support

Tell your lab mates and help us grow the program!
Mentee sign-up for the 2025 C. elegans Community Mentor Match program
The 2025 C. elegans Community Mentor Match is open to graduate students, postdocs, and faculty at any career stage. This survey collects information to help the committee (a) identify the most appropr...
docs.google.com
Reposted by Marc Perry