Marie Billaud
mariebillaud.bsky.social
Marie Billaud
@mariebillaud.bsky.social
Pronounce Bee-yo (🇫🇷)
Vascular biologist. Cat lover.
Asst Prof in Cardiovascular Medicine & Surgery at BWH/HMS in Boston
Formerly Pitt, UVA, Bordeaux.
Reposted by Marie Billaud
Very proud to share our lab’s recently published work in AJP-Heart

Early in my NIH K08 on #EndMT, we found an interesting signal in COL8A1 in athero, w/ biphasic response to TNF

🙏🏻 to ⭐️ postdoc Qian Li for leading us here (& @haoyin.bsky.social for summary!)

journals.physiology.org/doi/full/10....
November 21, 2025 at 1:54 PM
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Attempt number seven at uploading this video of intermediate filaments in an enormous COS7 cell. I have a feeling the BlueSky compression will not do it any favors.
November 21, 2025 at 3:54 AM
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Wanna be my colleague? We've got TT positions open!

1 in genetics/genomics jobs.missouristate.edu/postings/83638.
1 in biology education / open jobs.missouristate.edu/postings/83639.
1 in freshwater fisheries biology jobs.missouristate.edu/postings/83637

Date of first consideration is Jan 4 2026
November 20, 2025 at 11:21 PM
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Baym continues to make freakin' art. Must see thread/paper
Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/
www.science.org/doi/10.1126/...
Intracellular competition shapes plasmid population dynamics
From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...
www.science.org
November 20, 2025 at 11:29 PM
November 21, 2025 at 3:20 AM
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Me: "Taking vacation time is essential for emotional well-being, recovery from burnout, and future productivity. In all jobs but especially true in research, where mental focus is essential. Offering more vacation time should be required, and employees should take it"

Also me: "But not me though"
November 21, 2025 at 12:07 AM
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Actomyosin contractility and a threshold of cadherin cell adhesion is required during tissue fusion, say Camilla Teng @xsciteng.bsky.social, Jeffrey Bush @jeffbush.bsky.social and colleagues @ctbatucsf.bsky.social: rupress.org/jcb/article/...

#Development #Adhesion
November 20, 2025 at 7:45 PM
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Hey med students interested in CV research—consider applying to the Sarnoff research program for a fully funded year in an outstanding lab!

Please RT
November 20, 2025 at 8:04 PM
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Join us to pursue cutting-edge research at the interface of megakaryocyte biology and translational medicine. We have NIH-funded postdoc positions available to investigate platelet production and the broader functions of megakaryocytes. I’ll be attending ASH and would be happy to connect.
November 20, 2025 at 7:12 PM
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New on bioRxiv! 🚨
“Pericyte and Endothelial Primary Cilia and Centrioles have Disparate Organization Across the Brain Microvasculature”
This project studying #microvascular cells took an unexpected turn when we discovered that #pericytes have primary #cilia!
🔗 www.biorxiv.org/content/10.1...
🧪 🧵1/8
November 20, 2025 at 9:04 PM
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Thrilled to share this last little bit of my thesis work w/ @siegenthalerlab.bsky.social! 🐭🧠 Generating the PDGFRa cKO line we use in this paper was no trivial task, spanning multiple years (& a pandemic!) We were extremely excited to see this phenotype & even more excited to share it with everyone!
Our work out in @devbiol.bsky.social, PDGFra is needed for 🧠 perivascular fibroblast development... ⬇️ perivascular fibroblast = ⬇️ perivascular macrophage...cross-talk? 👀
Led by Hannah Jones @hejcell.bsky.social w/ Kelsey Abrams, Sophia Kim, excited for more projects w/ @fantauzzolab.bsky.social!
November 20, 2025 at 8:01 PM
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We are hiring a postdoc! 🧪
▶️ Project: nucleotide metabolism (genomics & biochemistry)
▶️ Start date: spring 2026 (flexible)
▶️ More info and application: tinyurl.com/3kjrbb2x
Please share 🌏

@fbm-unil.bsky.social @dib-unil.bsky.social @unil.bsky.social @snsf.ch
Career Opportunities: Postdoctoral position in cellular metabolism (22584)
tinyurl.com
November 20, 2025 at 6:26 AM
Reposted by Marie Billaud
For readers interested in therapeutic strategies based on inducing proximity between proteins, such as Halda's RIPTACs, here's a review on the field www.nature.com/articles/s41...
rdcu.be/eQzXF

and a news story on RIPTACs www.nature.com/articles/d41...
Induced proximity-based therapeutic modalities - Nature Reviews Drug Discovery
Induced proximity modalities encompass monovalent and bifunctional agents, such as molecular glues and proteolysis-targeting chimeras, that induce an interaction between biomolecules to functionally m...
www.nature.com
November 18, 2025 at 3:25 PM
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Yubo Zou, Deborah Leckband and colleagues find that EGFR is an essential component in E-cadherin force transduction complexes.
Highlight: journals.biologists.com/jcs/article/...
Article: journals.biologists.com/jcs/article/...
#OpenAccess #ReadandPublish
November 20, 2025 at 10:03 AM
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we need an ozempic that makes you feel well-rested
November 20, 2025 at 1:49 AM
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We are looking for a postdoctoral fellow to work on induced proximity 🤜🤛 and functional genomics! Join our team in Toronto 🇨🇦 to tackle major challenges in oncology and neurodegeneration. www.nature.com/naturecareer...
POSTDOCTORAL FELLOW - Toronto (City), Ontario (CA) job with Taipale Lab, Donnelly Centre, University of Toronto | 12849004
The Taipale lab in the Donnelly CCBR and University of Toronto is looking for a highly motivated Postdoctoral Fellow
www.nature.com
November 19, 2025 at 5:51 PM
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INCREDIBLE CURVES
November 19, 2025 at 10:43 PM
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Assistant Professor position posted for my Department, Biological Sciences at UNC Charlotte! Current research foci: Immunology, Microbiology, Virology; Biomolecular Function; Proteostasis; Genome Integrity; Epigenome Regulation; Cancer; Environmental Risks. jobs.charlotte.edu/postings/65141
Assistant Professor
Applicants should possess a Ph.D. in the biological sciences or related fields.Candidates are expected to document expertise in their specialty by a record of postdoctoral training, peer reviewed publ...
jobs.charlotte.edu
November 19, 2025 at 2:16 PM
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AOC sur la bulle IA :

"Nous ne devrions pas envisager un plan de sauvetage de ces entreprises [d'IA] alors que les soins de santé et l'aide alimentaire sont refusés aux Américains, précipitant certains problèmes mentaux que les gens tentent de résoudre eux-mêmes en utilisant les chatbots IA."
Trump's economy is being held up by a massive AI bubble.

A recent study found that of 300 companies that owned generative AI tools, 95% reported zero return on their investments.

We will not entertain a bailout of these companies should this bubble pop.
November 19, 2025 at 8:28 PM
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quick test with SAM3 - impressed with how well it seems to track long protrusions? prompted for "cell", does not find anything when looking for "fibroblast" or "nucleus"
November 19, 2025 at 8:15 PM
Reposted by Marie Billaud
Excited to share the latest from our lab (final version, open access):

Brain Capillary Ion Channels: Physiology and Channelopathies

Physiology | @apspublications.bsky.social

journals.physiology.org/doi/full/10....

@uvmlarnermed.bsky.social
November 19, 2025 at 1:38 PM
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A Consensus Statement in Nature Reviews Immunology clarifies the existing subset-based nomenclature for T cells. It also proposes an alternative modular nomenclature that is designed to be brief and flexible and to avoid ambiguity and unwanted implications. go.nature.com/3Xzfoqb #immunosky 🧪
November 19, 2025 at 2:17 PM
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Methodology
November 18, 2025 at 9:47 AM
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Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526
HMS - Postdoctoral Fellow in BCMP, Brown Lab
We invite applicants for a postdoctoral fellow position in the Brown lab at Harvard Medical School in Boston, Massachusetts. The Brown lab uses structural, biophysical, and biochemical approaches to d...
academicpositions.harvard.edu
November 18, 2025 at 8:05 PM
Reposted by Marie Billaud
NEW: Epstein survivors release the most powerful PSA I have ever seen.

Make this go viral so every member of the House of Representatives sees it.
November 16, 2025 at 11:43 PM