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lacarlson.bsky.social
Lars-Anders Carlson
@lacarlson.bsky.social
1.8K followers 260 following 220 posts
Structural virology group leader at Umeå University, Sweden.
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Reposted by Lars-Anders Carlson
rberntsson.bsky.social
Ronnie Berntsson @rberntsson.bsky.social · 3d
This is really cool! If you want to get a card game that explains microorganisms - now's your chance!

www.umu.se/en/news/rese...
Researchers' card game teaches children about microorganisms
Hope to spark curiosity about life beneath the water’s surface – with playful game cards.
www.umu.se
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Reposted by Lars-Anders Carlson
jpkreysing.bsky.social
Jan Philipp Kreysing @jpkreysing.bsky.social · 3d
❓What if you could peek between your tilt series ❓ We are proud to introduce cryoTIGER -- deep-learning based tilt interpolation for enhanced reconstruction in cryo-ET. A great collaboration between Turoňová lab, @becklab.bsky.social, @hummerlab.bsky.social #teamtomo www.nature.com/articles/s42...
cryoTIGER: deep-learning based tilt interpolation generator for enhanced reconstruction in cryo electron tomography - Communications Biology
Deep learning-based interpolation using cryoTIGER enhances angular sampling in cryoET, improving 3D reconstructions, particle localization, and structural recovery without increasing electron dose.
www.nature.com
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Reposted by Lars-Anders Carlson
istaresearch.bsky.social
Institute of Science and Technology Austria (ISTA) @istaresearch.bsky.social · 3d
Join us for the Austrian Cryo-EM Symposium from Nov 11–12 at ISTA! Top speakers, cutting-edge cryo-EM, and a chance to explore Vienna & the ISTA campus. Register now 👉 cryoem-symposium.pages.ist.ac.at/registration/

#cryoEM
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lacarlson.bsky.social
Lars-Anders Carlson @lacarlson.bsky.social · 3d
www.nobelprize.org/prizes/peace...
Nobel Peace Prize 2025
The Nobel Peace Prize 2025 was awarded to Maria Corina Machado “for her tireless work promoting democratic rights for the people of Venezuela and for her struggle to achieve a just and peaceful transi...
www.nobelprize.org
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lacarlson.bsky.social
Lars-Anders Carlson @lacarlson.bsky.social · 3d
This sounds really interesting!
carmensmp.bsky.social
Carmen San Martín @carmensmp.bsky.social · 3d
Pleased to share our latest publication on #adenovirus structure: dx.plos.org/10.1371/jour...
Aviadenovirus structure: A highly thermostable capsid in the absence of stabilizing proteins
Author summary The International Committee for Virus Taxonomy currently recognizes over 120 adenovirus species, grouped in six genera, with host range covering all kinds of vertebrates. Although all a...
dx.plos.org
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Reposted by Lars-Anders Carlson
clauswilke.com
Claus Wilke @clauswilke.com · 5d
Biology is much more complicated than most non-biologists can imagine. And AI is not going to change this anytime soon.
blog.genesmindsmachines.com/p/we-still-c...
We still can’t predict much of anything in biology
Biology is hard. Yes, even for AI.
blog.genesmindsmachines.com
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Reposted by Lars-Anders Carlson
sciezgin.bsky.social
Erdinc Sezgin @sciezgin.bsky.social · 4d
The last edition in Lisbon was incredible! I’m sure this one will be nothing short of that!
biologists.bsky.social
The Company of Biologists @biologists.bsky.social · 4d
Registration is now open to attend Journal of Cell Science's meeting on Imaging Cell Dynamics, organised by Francesca Bottanelli, Guillaume Jacquemet, Michael Way and Giulia Zanetti.

Find out more: biologists.com/meetings/jcs...

#JCSimaging #Microscopy #Microscope #Imaging #Cells #CellScience
Imaging Cell Dynamics 11-14 May 2026 Montanyà Hotel, Catalonia, Spain Register now - early-bird deadline: 16 January 2026 Journal of Cell Science Meeting
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Reposted by Lars-Anders Carlson
odedrechavi.bsky.social
Oded Rechavi @odedrechavi.bsky.social · 4d
When you’re editing your draft for the 100th time and thinking “What will the reviewers think of my manuscript?”, remember that they’ll be reading it in this position.
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Reposted by Lars-Anders Carlson
jowolff.bsky.social
Jo Wolff @jowolff.bsky.social · 4d
This was not a sample of academics.
yougov.co.uk
YouGov @yougov.co.uk · 4d
How many browsing tabs do you typically have open?*

1: 6%
2-5: 54%
6-10: 14%
11-20: 8%
21-30: 2%
More than 30: 3%

*across all windows, on desktop/laptop

yougov.co.uk/topics/techn...
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Reposted by Lars-Anders Carlson
mclellanlab.bsky.social
Jason McLellan @mclellanlab.bsky.social · 4d
I'm honored to receive a MacArthur Fellowship. As always, I extend my sincerest thanks to all my wonderful mentors, colleagues, collaborators, admins, and trainees who make this work possible. #MacFellow
texasscience.bsky.social
Texas Science @texasscience.bsky.social · 4d
UT Austin has a new “genius grant” recipient!

Texas Science professor Jason McLellan has been awarded a MacArthur Fellowship — aka the “genius grant” — by The MacArthur Foundation.

#TexasScience @mclellanlab.bsky.social #MacArthurGenius @utaustin.bsky.social
cns.utexas.edu/news/accolad...
Virus Slayer Awarded ‘Genius Grant’ by MacArthur Foundation
The award recognizes Jason McLellan’s work to investigate how viruses infect our cells and to develop new treatments for infectious disease.
cns.utexas.edu
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Reposted by Lars-Anders Carlson
denkenny.bsky.social
Kenneth Ehses @denkenny.bsky.social · 4d
✨Excited that the main project of my PhD is now available as a pre-print on #bioRxiv

Here, we used #CryoET to visualise mitochondrial proteostatic stress and together with SPA #CryoEM shed light into the functional cycle of the Hsp60:10 chaperone system. #TeamTomo

🔗 www.biorxiv.org/content/10.1...
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Reposted by Lars-Anders Carlson
juanbonifacino.bsky.social
Juan S. Bonifacino @juanbonifacino.bsky.social · 5d
Excited to share our latest manuscript by @saikat2025.bsky.social and an international team, reporting variants in the EARP- and GARP-interacting protein EIPR1 associated with a neurodevelopmental disorder. Will send you the PDF if you can’t access the article: academic.oup.com/brain/articl...
EIPR1 variants cause a neurodevelopmental disorder with endolysosomal and dense core vesicle defects
Abstract. EIPR1 (EARP-interacting protein 1, formerly known as TSSC1) is a WD40-domain protein that interacts with the EARP (endosome-associated recycling
academic.oup.com
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Reposted by Lars-Anders Carlson
rodai.bsky.social
Roni Odai @rodai.bsky.social · 11d
Viral AlphaFold Database (VAD) is live in Science Advances

~27,000 predicted viral protein monomers & homodimers

Conserved folds across bacteria, archaea & eukaryotic viruses

New toxin–antitoxin system KreTA uncovered

Vast “functional darkness” remains uncharted

www.science.org/doi/10.1126/...
The Viral AlphaFold Database of monomers and homodimers reveals conserved protein folds in viruses of bacteria, archaea, and eukaryotes
VAD is a Viral AlphaFold Database of protein monomers and homodimers from viruses infecting hosts across the tree of life.
www.science.org
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Reposted by Lars-Anders Carlson
dereklowe.bsky.social
Derek Lowe @dereklowe.bsky.social · 5d
I don’t think I’ve ever had more fun in the lab than when I was making MOFs myself (and trying to use them for small-molecule X-ray structure determination). So let me celebrate by posting a few of the MOF crystals I prepared:
Bright green transparent metal-organic framework crystals prepared with copper and a “multipronged” carboxylic acid ligand. The crystals formed blocky roughly rectangular pieces with some very large emerald-like chunks. Pink/red transparent metal-organic framework crystals prepared with cobalt and a “multipronged” carboxylic acid ligand. The crystals formed as a mixture of long rectangular types and aggregated chunks. Purple transparent metal-organic framework crystals prepared with cobalt and a “multipronged” carboxylic acid ligand. The crystals formed long slightly blocky needles. Clear transparent metal-organic framework crystals prepared with zirconium and a “multipronged” carboxylic acid ligand. The crystals formed chunky hexagons.
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Reposted by Lars-Anders Carlson
lindorfflarsen.bsky.social
Kresten Lindorff-Larsen @lindorfflarsen.bsky.social · 5d
A good day to remember John Gurdon’s school report from his biology master at Eton
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Reposted by Lars-Anders Carlson
briggsgroup.bsky.social
Briggs Group @briggsgroup.bsky.social · 7d
The mechanistic basis of cargo selection during Golgi maturation. From Rebecca Taylor, @katciazynska.bsky.social, @jggkaufman.bsky.social & @grigorytagiltsev.bsky.social at @mpibiochem.bsky.social with David Owen and Sean Munro's group @cellbiol-mrclmb.bsky.social | www.science.org/doi/10.1126/...
The mechanistic basis of cargo selection during Golgi maturation
Resident proteins of the Golgi recycle in vesicles and the protein GOLPH3 enables the COPI vesicle coat to accomplish this.
www.science.org
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lacarlson.bsky.social
Lars-Anders Carlson @lacarlson.bsky.social · 5d
Cool conference!
cryocloudio.bsky.social
CryoCloud @cryocloudio.bsky.social · 6d
CryoCloud is heading to Women in Electron Microscopy #WeM2025 this week!

We’re proud to sponsor this inaugural event supporting women in electron microscopy.

Our own @ievadr.bsky.social will speak on cloud-native automation to enable high-throughput #cryoEM for drug discovery.

See you there!
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Reposted by Lars-Anders Carlson
rcsbpdb.bsky.social
RCSB Protein Data Bank @rcsbpdb.bsky.social · 5d
The genome of ebola virus contains instructions for building seven proteins, which assemble with the genomic RNA to form one of the deadliest viruses.
PDB101: Molecule of the Month: Ebola Virus Proteins
Structures of ebola virus proteins are giving new hope for fighting this deadly virus
pdb101.rcsb.org
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Reposted by Lars-Anders Carlson
Thelonevirologist @thelonevirologist.bsky.social · 6d
Immunogenicity of a trivalent haemorrhagic fever vaccine candidate against Sudan virus, Marburg virus and Lassa virus in an mpox vaccine

www.microbiologyresearch.org/content/jour...
Immunogenicity of a trivalent haemorrhagic fever vaccine candidate against Sudan virus, Marburg virus and Lassa virus in an mpox vaccine
A multivalent vaccine targeting high-consequence infectious diseases in Sub-Saharan Africa (SSA), which are linked to high mortality, morbidity and overlapping clinical manifestations, would significa...
www.microbiologyresearch.org
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Reposted by Lars-Anders Carlson
vdlorenzo.bsky.social
Victor de Lorenzo (CNB, Madrid) @vdlorenzo.bsky.social · 6d
Université Grenoble Alpes opens a full professorship in microbiology in 2026. The selected candidate will develop their research program on quantitative approaches in microbiology in the Laboratoire Interdisciplinaire de Physique. More info: liphy.univ-grenoble-alpes.fr/en/join-us/r...
Professorship (tenure) in 'Quantitative approaches in microbiology' (CNU Sections 64/65) | LIPhy - Université Grenoble Alpes
liphy.univ-grenoble-alpes.fr
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Reposted by Lars-Anders Carlson
chillzaa.bsky.social
Chris H. Hill @chillzaa.bsky.social · 6d
Enteroviruses cause over a billion infections each year, but the details of how their genomes capture host ribosomes have remained elusive. I'm pleased to share a new preprint from Miguel in our group, providing some new insights into this problem:
www.biorxiv.org/content/10.1...
Structural and mechanistic insights into translation initiation on the enterovirus Type 1 IRES
Enteroviruses are a widespread and diverse set of pathogens responsible for over ~1 billion human infections annually. Upon cell entry, translation of the virus genome is mediated by an internal ribos...
www.biorxiv.org
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Reposted by Lars-Anders Carlson
boghuma.bsky.social
BK. Titanji @boghuma.bsky.social · 6d
A new Nature Medicine study analyzing health records from >100 million people in the US offers compelling evidence that reactivation of varicella-zoster virus (VZV) ,the same virus that causes chickenpox and shingles may contribute to dementia risk.
www.nature.com/articles/s41...
Varicella-zoster virus reactivation and the risk of dementia - Nature Medicine
Large-scale longitudinal health records reveal consistent association of varicella-zoster virus reactivation with dementia.
www.nature.com
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Reposted by Lars-Anders Carlson
daumlab.bsky.social
The Daum Lab @daumlab.bsky.social · 7d
Out in Science Advances: Our #cryoEM structure of HFTV1, a virus infecting the halophile #archaea. *First full atomic structure (containing all structural proteins) of any tailed virus!* Congrats and thanks to all co-authors and our fantastic collaborators! www.science.org/doi/10.1126/...
Cryo-EM resolves the structure of the archaeal dsDNA virus HFTV1 from head to tail
This structure of an archaeal tailed virus (arTV) provides detailed insights into arTV assembly and infection mechanisms.
www.science.org
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Reposted by Lars-Anders Carlson
sjorsscheres.bsky.social
Sjors Scheres @sjorsscheres.bsky.social · 8d
If you are interesting in developing new algorithms for #cryoEM as a #PhD student or as a #postdoc, then do email or DM me. We have exciting opportunities coming up.
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lacarlson.bsky.social
Lars-Anders Carlson @lacarlson.bsky.social · 8d
These stoic thoughts are hard to digest for us today. Yet they can be traced back to Socrates, and are perhaps still worth considering?
daily-stoic.bsky.social
Daily Stoic @daily-stoic.bsky.social · 8d
"It can ruin your life only if it ruins your character. Otherwise it cannot harm you" Marcus Aurelius
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