CryoCloud
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cryocloudio.bsky.social
CryoCloud
@cryocloudio.bsky.social
We provide a cloud-native platform for cryo-EM data analysis which integrates cloud storage, scalable compute and an intuitive web-app for fast and easy end-to-end cryo-EM data analysis.
🔥 Three years ago, the CryoCloud platform went live 🎉

Today, scientists from 25+ countries rely on it every day for analysing their structural biology data – and we couldn’t be prouder of how far things have come.

Thank you to all our users, collaborators, and early supporters 💙

#CryoEM
December 5, 2025 at 9:20 AM
🚀 CryoCloud v2.17 is live!

This release introduces Targets – a new way to organise datasets & projects around your molecule of interest.

Targets make it easier to browse results, store reference files in one place and launch automated workflows.

connect.cryocloud.io/release-note...

#CryoEM
December 5, 2025 at 6:11 AM
November Map of the Month: CDK-activating kinase (CAK), an oncology target bound to the covalent inhibitor THZ1 💊

We reprocessed EMPIAR‑11793 and produced a 2.5 Å map of the ~85 kDa CAK-THZ1 complex using CryoCloud.

🔬 Dataset size: 12,572 movies
🧠 Total compute time: 52 hours

#CryoEM #CryoCloud
November 26, 2025 at 10:23 AM
🚀 CryoCloud v2.16 is live!

This release introduces filament support, including filament picking, visualisation, and a new Initial Model job type for helical workflows.

Full release notes → connect.cryocloud.io/release-note...

#CryoEM #StructuralBiology
November 21, 2025 at 4:19 PM
🌟 Employee Spotlight: Anna Boronina

Anna brings a strong mix of ML and software engineering to #CryoCloud. She’s behind our ML-based particle picker, which has expanded since its initial release to include contamination segmentation, models for diverse targets & lightning-fast performance.

#cryoEM
November 19, 2025 at 8:23 AM
Back from a #PSDI2025 in Basel. Lots of good discussions and clear interest in practical ways to handle growing cryo-EM and X-ray data volumes.

We shared results from our large-scale automated analysis of 53 EMPIAR datasets (key takeaways in the comment below!)

#CryoEM #StructuralBiology
November 13, 2025 at 9:10 AM
We’re heading to #PSDI2025!

Meet the CryoCloud team and don’t miss our talks:
⚡ Sun 9 Nov: Towards Automating Cryo-EM Data Analysis
🚀 Tue 11 Nov: Accelerating Data Analysis with CryoCloud

Drop by our booth or book a chat 👇
connect.cryocloud.io/meetings/cry...

#CryoEM #XrayCrystallography
November 5, 2025 at 8:39 AM
October Map of the Month: GLP-1R

With pharma racing to develop next-generation obesity and diabetes drugs, this #GPCR needs no introduction 💊

We reprocessed EMPIAR-10673, showing GLP-1R bound to its natural ligand GLP-1, and achieved a 2.7 Å map on CryoCloud using 40 h of compute.

#CryoEM
October 28, 2025 at 11:09 AM
🌟 Employee Spotlight: Tadej Satler (@tadejsatler.bsky.social)

Tadej brings deep scientific and computational expertise to CryoCloud. His recent work on GPU-accelerated motion correction (MotionCorr CC) is a key step toward faster, more accessible cryo-EM.

Proud to have him on the team! 🚀

#CryoEM
October 24, 2025 at 7:57 AM
🚀 CryoCloud version 2.13 is here!

Highlights:
🔹 Adjust map visualisation with new, easily-accessible iso-level slider ⬇️
🔹 Create particle subsets using metadata values
🔹 Clearer dataset-import feedback
🔹 Custom browser tab names, and more

Full notes: connect.cryocloud.io/release-note...

#CryoEM
October 23, 2025 at 1:34 PM
🚀 CryoCloud v2.12 is here!

This release brings major project grid usability updates, including filtering by processing branch, so you can highlight an entire job tree and focus on one processing path at a time (preview below!)

Full release notes: connect.cryocloud.io/release-note...

#CryoEM
October 17, 2025 at 7:51 AM
⏰ Tomorrow!

Join us for the CryoCloud #XRayCrystallography webinar featuring a short introduction to the new pipeline and a panel discussion on today’s challenges and opportunities in high-throughput XRC data processing.

events.teams.microsoft.com/event/6f09a4...

#CryoCloud #StructuralBiology
October 15, 2025 at 10:18 AM
🚀 CryoCloud MotionCorr – our new GPU-accelerated motion correction is here!

Released last week as part of CryoCloud v2.11, our new GPU-accelerated motion correction algorithm delivers up to 4× faster performance than the legacy CPU-based Relion implementation.

v2.11 notes: t.co/zK4YKotSWI

#CryoEM
October 14, 2025 at 10:30 AM
🚀 CryoCloud v2.11 is here!

Version 2.11 brings up to 4x faster motion correction, contamination detection in CryoCloud Picker (see a preview below!), and major performance boosts across the platform.

Full release notes: connect.cryocloud.io/release-note...

#CryoEM #CryoCloud
October 10, 2025 at 3:27 PM
⏳ 1 Week to Go!

After introducing CryoCloud’s integration of Global Phasing’s Pipedream workflow, we’ll be joined by four experts to discuss the challenges and opportunities in high-throughput #XrayCrystallography.

Register here: events.teams.microsoft.com/event/6f09a4...
October 10, 2025 at 12:27 PM
CryoCloud is heading to Women in Electron Microscopy #WeM2025 this week!

We’re proud to sponsor this inaugural event supporting women in electron microscopy.

Our own @ievadr.bsky.social will speak on cloud-native automation to enable high-throughput #cryoEM for drug discovery.

See you there!
October 7, 2025 at 9:11 AM
📢 CryoCloud Newsletter – Issue #2 is here!

💎 New X-ray Crystallography pipeline
🧬 Biologics case studies: antibodies & vaccines
🚀 Platform release notes
🎤 CryoCloud at WeM 2025
👋 Team update: Welcome, Josh!
📅 Upcoming events & more

Read it here: connect.cryocloud.io/newsletter-o...

#cryoEM #XRC
October 6, 2025 at 11:23 AM
🚀 CryoCloud Platform Release 2.10.1 is here!

This is a big one – CryoCloud now supports X-ray Crystallography alongside #cryoEM 💎

📖 Read the full release notes, including other improvements and bug fixes: connect.cryocloud.io/release-note...

#CryoCloud #XrayCrystallography #StructuralBiology
October 3, 2025 at 8:26 AM
🚀 New in CryoCloud: Automated X-ray Crystallography Data Processing!

Join our launch webinar on Oct 16 (11 AM ET | 5 PM CET) featuring a CDK2 case study + industry panel on high-throughput XRC.

👉 Register: lnkd.in/ev4e7K_h

#StructuralBiology #XRayCrystallography #XRC #CryoEM
October 2, 2025 at 8:09 AM
📣 Live from the Dutch Structural Biology Meeting in Delft! Robert (@riborob.bsky.social) is presenting our CryoCloud poster on accelerating #cryoEM workflows. We’re also sponsoring the Poster Prize 🧦🎉 Big thanks to Arjen Jakobi (@cryotud.bsky.social) for organising. Excited for today’s discussions!
September 26, 2025 at 12:22 PM
September Map of the Month: Small Data, Big Insights ⚡️

From just 233 movies, CryoCloud delivered a 3.2 Å SARS-CoV-2 spike map in 3.5 h.

Fast and efficient #cryoEM, exactly what vaccine design teams need when screening dozens of antigen variants per day.

📬 DM or [email protected] for more info!
September 24, 2025 at 12:23 PM
Thrilled to welcome Dr Joshua White as Senior Application Scientist at CryoCloud! With deep expertise in single-particle analysis & end-to-end #cryoEM workflows, Josh will lead data analysis, user training & support. Excited to have his experience & energy on board! 🚀

@jbrwhite.bsky.social
September 19, 2025 at 11:50 AM
The CryoCloud team just returned from a retreat in the Belgian Ardennes 🌿 For the first time, all 11 of us met in person, with colleagues from 6 countries. We had work sessions, walks, meals, spotted deer 🦌 … and launched our first edition of CryoCloud #cryoEM socks! 🚀
September 15, 2025 at 8:50 AM
🌟 Employee Spotlight: Ilja Gubins ‪(@igubins.bsky.social‬)

🚀 From building CryoCloud’s multi-cloud infrastructure from scratch to leading ISO certification & security efforts, Ilja has been the driving force of our technical foundation.

🙌 We're proud to have him as our Co-Founder & CTO!

#CryoEM
August 28, 2025 at 10:13 AM
Tomorrow’s the day! 🚀

Join our webinar "CryoCloud: Secure & Automated Cryo-EM Data Processing in the Cloud" to learn how CryoCloud helps streamline #cryoEM workflows with automation, scalability, and cloud-native tools.

Register here: events.teams.microsoft.com/event/85b6a4...

#structuralbiology
📢 Webinar announcement!

CryoCloud: Secure & Automated Cryo-EM Data Processing in the Cloud

Join to get a tour of the app and learn about real-world case studies of challenging targets 🔬

📅 August 26
🕓 4:00 PM CEST / 10:00 AM EDT

👉 Register here: events.teams.microsoft.com/event/85b6a4...

#cryoEM
August 25, 2025 at 12:23 PM