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Reposted by Joel Selkrig

Pedro Beltrao @pedrobeltrao.bsky.social · 4d

new preprint: Ubiquitin is a protein modification linked with degradation but known to regulate other functions. Over 100k ubiquitination sites have been discovered and here we (@julianvangerwen.bsky.social + others) try to prioritize those most critical to the cell www.biorxiv.org/content/10.1...

The functional landscape of the human ubiquitinome

Protein ubiquitination regulates cell biology through diverse avenues, from quality control-linked protein degradation to signaling functions such as modulating protein-protein interactions and enzyme...

www.biorxiv.org

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Joel Selkrig @jselkrig.bsky.social · 1d

Important (and meticulous) genetic groundwork by the @typaslab.bsky.social and Carlos Voogt on gut microbiome Bacteroides species! Enormous value for the functional microbiome research community

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 2d

A toolkit for transposon libraries and functional genomics in intestinal Bacteroidales https://www.biorxiv.org/content/10.1101/2025.10.10.681549v1

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Reposted by Joel Selkrig

Drosophila Spain @drosospain.bsky.social · 2d

Model organisms, in particular non-mammalian model organisms, such as yeast, Caenorhabditis elegans, #Drosophila and zebrafish, have long stood at the centre of biological discovery www.nature.com/articles/s41...

Reaffirming the value of model organisms in training scientific minds - Nature Cell Biology

As biomedical research prioritizes human models and translational promise, classic model organisms are increasingly dismissed. Here we argue that they have a lasting value, both in enabling discovery and in cultivating scientific thinking, by training researchers in systems reasoning, integrative thinking and independent inquiry.

www.nature.com

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Reposted by Joel Selkrig

AnniZLab: [🦠, 🧬 , ✨] @annizlab.bsky.social · 1d

Fascinating Evo mechanism: diversity-generating retroelements (DGRs)! Highly abundant and frequently horizontally transferred - diversifying ligand-binding domains in gut Bacteroides! 🧪🦠 #microsky #microbiomesky
www.science.org/doi/10.1126/...

Targeted protein evolution in the gut microbiome by diversity-generating retroelements

Diversity-generating retroelements (DGRs) accelerate evolution by rapidly diversifying variable proteins. The human gastrointestinal microbiota harbors the greatest density of DGRs known in nature, su...

www.science.org

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Reposted by Joel Selkrig

The Francis Crick Institute @crick.ac.uk · 3d

We're now recruiting early career group leaders at the Crick to lead ambitious research programmes and explore bold scientific questions.

Hear our Director, Edith Heard, explain why the Crick is a unique place for curiosity-driven research.

Apply now ➡️ www.crick.ac.uk/careers-stud...

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Reposted by Joel Selkrig

Jörg Vogel @jorg-vogel-lab.bsky.social · 4d

Two group leader positions available in the broader areas of RNA science, RNA technologies, and RNA medicine. Attractive packages and a great environment. Come and join us at Helmholtz RNA Würzburg, Bavaria.

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Reposted by Joel Selkrig

Shabaana Khader @khadershabaana.bsky.social · 7d

UChicago Microbiology is searching for tenured or tenure-track faculty working in host-pathogens interactions, viral and bacterial pathogenesis, and emerging infectious diseases. Come join our vibrant Department! microbiology.uchicago.edu
Apply here apply.interfolio.com/174404

Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

apply.interfolio.com

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Reposted by Joel Selkrig

Cameron Thrash @jcamthrash.bsky.social · 10d

A new paradigm for outer membrane protein biogenesis in the Bacteroidota www.nature.com/articles/s41... #jcampubs

A new paradigm for outer membrane protein biogenesis in the Bacteroidota - Nature

Structural and biochemical studies of the β-barrel-assembly machinery from Flavobacterium johnsoniae reveal a subunit composition and assembly that are distinct from those of the canonical Escherichia coli complex.

www.nature.com

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Reposted by Joel Selkrig

Géraldine Laloux @lalouxlab.bsky.social · 26d

🚨New paper out! #MicroSky
Studying obligate predators like Bdellovibrio bacteriovorus is tricky—essential genes for predation are also essential for survival.
We expanded its genetic toolbox:
🧬promoters to fine-tune expression
🧬IPTG-inducible system
🧬CRISPRi for rapid knockdown
bit.ly/46GUn2c
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Expanding the genetic toolbox of the obligate predatory bacterium Bdellovibrio bacteriovorus with inducible gene expression and CRISPR interference

Inducible gene expression and CRISPR interference-mediated depletion in the predatory bacterium Bdellovibrio bacteriovorus.

academic.oup.com

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Reposted by Joel Selkrig

Tom Hitch @tcahitch.bsky.social · 18d

The main work from my time in Aachen is now out 🎉 if you have wanted to make a SynCom that captures the functional-landscape of microbiota, MiMiC2 makes that possible based on metagenomic data! 1/7 doi.org/10.1093/isme...

Function-Based Selection of Synthetic Communities Enables Mechanistic Microbiome Studies

Abstract. Understanding the complex interactions between microbes and their environment requires robust model systems such as synthetic communities (SynCom

doi.org

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Reposted by Joel Selkrig

EMBL @embl.org · Aug 7

We’re looking for curious, innovative science leaders at EMBL Heidelberg! 🔬🧬🦠

Join a vibrant, interdisciplinary community where collaboration and innovation are nurtured at all levels.

Take a look at these four open positions 👇

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Reposted by Joel Selkrig

Rhys Grinter @rhyswg.bsky.social · 23d

The outer membrane of Gram-negative bacteria blocks many antibiotics. Our latest work reveals that L-type pyocins bypass this barrier by inactivating the BAM complex, killing Pseudomonas aeruginosa without entering the cell, providing a new blueprint for beating antibiotic resistance.

A Protein Antibiotic Inhibits the BAM Complex to Kill Without Cell Entry

Many antibiotics are ineffective against Gram-negative pathogens such as Pseudomonas aeruginosa because they cannot penetrate the bacterial outer membrane. Here, we show that protein antibiotics calle...

www.biorxiv.org

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Reposted by Joel Selkrig

Max-Planck-Gesellschaft @maxplanck.de · 28d

Early-career researchers: want to run your own lab? 🌟Max Planck Research Groups offer 6+ years, up to €2.7M in funding, open-topic freedom, team support & tenure-track opportunities. Intrigued? 😃Apply by Oct 14, 2025! www.mpg.de/max-planck-r...

Graphic with a blue background and light green dots. The text 'call for applications' appears in green, and 'Ausschreibung' in white. A white arrow on the right points diagonally upward.

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Reposted by Joel Selkrig

Enninga Lab @enningalab.bsky.social · 24d

🦠 Mycobacteria aren't just tough, they're interior designers! 🦠 Check out our latest #preprint 🚨, led by our PhD student @camimille.bsky.social , where we show that #Mycobacterium tuberculosis builds secret cytoplasmic membranes to adapt its metabolism and sneak past immunity 🤫

Thread coming soon!

bioRxiv Microbiology @biorxiv-microbiol.bsky.social · 25d

Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection https://www.biorxiv.org/content/10.1101/2025.09.17.676823v1

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Joel Selkrig @jselkrig.bsky.social · 24d

Congratulations guys on this nice work!

Reposted by Joel Selkrig

Thomas Clavel @tclavel.bsky.social · 24d

Interested in the design of defined microbial communities for fundamental research and applications? Hope this work & tool will help you 👇 As always @tcahitch.bsky.social has been a driving factor ⭐⭐⭐! github.com/ClavelLab/Mi...; academic.oup.com/ismej/advanc...

Validate User

academic.oup.com

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Reposted by Joel Selkrig

John Lees @bacpop.org · 25d

The EMBL PhD programme is open until 13th October (entry ~Sep 2026):
www.embl.org/about/info/e...

We have three positions in microbial genomics at EMBL-EBI, including one in my group. Please do apply, or if you know anyone that would be interested pass on to them

EMBL International PhD Programme – Unique in the world and waiting for you!

www.embl.org

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Reposted by Joel Selkrig

Oliver Bossdorf @bossdorf.bsky.social · Sep 10

Job Alert! The University of Tübingen is hiring a FULL PROFESSOR (W3) in FUNCTIONAL ECOLOGY! Come and join our institute, and maybe our new excellence clusters @terra-cluster.org and @greenrobust.de. @gfoesoc.bsky.social @britishecologicalsociety.org @ecologicalsociety.bsky.social Please repost!

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Reposted by Joel Selkrig

Jörg Vogel @jorg-vogel-lab.bsky.social · Sep 10

Looking for a new approach to studying or eliminating phages? Check out our study introducing anti-phage ASOs (antisense oligos) out in @Nature today. nature.com/articles/s4158…

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Joel Selkrig @jselkrig.bsky.social · Sep 10

Congratulations Annika and Co!

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Reposted by Joel Selkrig

Willem van Schaik @wvschaik.bsky.social · Sep 6

Reminder that we are recruiting an Assistant Professor Bacterial Genomics @imibirmingham.bsky.social.

www.jobs.ac.uk/job/DOO184/a...

Deadline 24 Sept.

Assistant Professor (Research and Education) in Bacterial Genomics at University of Birmingham

Looking for a new job opportunity in academia? Check out this job opening for a Assistant Professor (Research and Education) in Bacterial Genomics on jobs.ac.uk!

www.jobs.ac.uk

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Reposted by Joel Selkrig

Ákos T Kovács @evolvedbiofilm.bsky.social · Sep 5

Assistant Professor position in the Microbiome Engineering group (Prof Sahar El Aidy) at University of Amsterdam

Assistant Professor in Microbiome Imaging and Functional Analysis
werkenbij.uva.nl/en/vacancies...

Vacancy — Assistant Professor in Microbiome Imaging and Functional Analysis

Are you pioneering molecular tools and applying advanced imaging strategies to uncover how microbial communities are organized and interact in space and time? If so, we invite you to join The Swammerd...

werkenbij.uva.nl

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Reposted by Joel Selkrig

Alan McNally @alanmcn1.bsky.social · Sep 3

We have a position for an Assist Prof in Microbial Genomics in our School of III.

Hod Joan Geoghegan will be happy to field questions if you are interested. No specific area of microbial genomics preferred so please do consider it

www.jobs.ac.uk/job/DOO184/a...

Assistant Professor (Research and Education) in Bacterial Genomics at University of Birmingham

Apply now for the Assistant Professor (Research and Education) in Bacterial Genomics role on jobs.ac.uk - the leading job board for higher education jobs. View details.

www.jobs.ac.uk

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Joel Selkrig @jselkrig.bsky.social · Sep 3

Fantastic work Judith, congratulations!!!!

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Reposted by Joel Selkrig

The Ferrari Lab @theferrarilab.bsky.social · Aug 26

Excited to announce a search for an Associate or Full Professor in Infectious Disease Modeling at Penn State's Center for Infectious Disease Dynamics. Details at link and below.

psu.wd1.myworkdayjobs.com/en-US/PSU_Ac...

Full or Associate Professor in Infectious Disease Modeling

APPLICATION INSTRUCTIONS: CURRENT PENN STATE EMPLOYEE (faculty, staff, technical service, or student), please login to Workday to complete the internal application process. Please do not apply here, a...

psu.wd1.myworkdayjobs.com

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