Pedro Friedmann Angeli
@angelifriedmann.bsky.social
Reposted by Pedro Friedmann Angeli
Why the brand of phase separation proposed by Tony Hyman is pseudoscientific and why it makes him incompatible with leadership of EMBL @embl.org, a major European institution in Molecular Biology #MolecularBiology
🧵A thread
#science #PhaseSeparation #BlueSkyScience #AcademicBluesky #BioSky
🧵A thread
#science #PhaseSeparation #BlueSkyScience #AcademicBluesky #BioSky
November 29, 2025 at 3:12 PM
Why the brand of phase separation proposed by Tony Hyman is pseudoscientific and why it makes him incompatible with leadership of EMBL @embl.org, a major European institution in Molecular Biology #MolecularBiology
🧵A thread
#science #PhaseSeparation #BlueSkyScience #AcademicBluesky #BioSky
🧵A thread
#science #PhaseSeparation #BlueSkyScience #AcademicBluesky #BioSky
I’m on the last season of Stranger Things and it’s basically El Chavo del 8 now: everyone’s ‘a kid’, but the faces say otherwise
November 28, 2025 at 9:00 PM
I’m on the last season of Stranger Things and it’s basically El Chavo del 8 now: everyone’s ‘a kid’, but the faces say otherwise
an urgent change in the system is needed and its not the one german politicians are advocating for -
German academia: great place to work? You should think twice before giving it a try: Permanent positions are very rare, most scholars have to drop out after some precarious years. @dianakwon.bsky.social has written a great piece about this for @nature.com and also talked to yours truly. #IchBinHanna
How to stop the revolving door of German academia
Germany is one of the most popular destinations for students and scholars worldwide, but those pursuing academic careers face significant hurdles to success.
www.nature.com
November 28, 2025 at 4:33 PM
an urgent change in the system is needed and its not the one german politicians are advocating for -
Reposted by Pedro Friedmann Angeli
Recently out: “Uniform dynamics of cohesin-mediated loop extrusion in living human cells”. In this study led by brilliant former PhD student Thomas Sabaté we use live cell microscopy and polymer simulations to characterize how DNA loops and TADs form in human cells by cohesin-driven extrusion. (1/4)
November 23, 2025 at 4:35 PM
Recently out: “Uniform dynamics of cohesin-mediated loop extrusion in living human cells”. In this study led by brilliant former PhD student Thomas Sabaté we use live cell microscopy and polymer simulations to characterize how DNA loops and TADs form in human cells by cohesin-driven extrusion. (1/4)
Reposted by Pedro Friedmann Angeli
Jair agora vai vomitar merda em uma sala da superintendência da duas letras...
November 22, 2025 at 10:28 AM
Jair agora vai vomitar merda em uma sala da superintendência da duas letras...
Day 30: manuscript still ‘with editor’.
I’m sure when the decision finally comes, the handling fee will reflect the immense effort of… letting it sit in the queue for a month.
Modern publishing: pay to wait.
I’m sure when the decision finally comes, the handling fee will reflect the immense effort of… letting it sit in the queue for a month.
Modern publishing: pay to wait.
November 21, 2025 at 5:24 PM
Day 30: manuscript still ‘with editor’.
I’m sure when the decision finally comes, the handling fee will reflect the immense effort of… letting it sit in the queue for a month.
Modern publishing: pay to wait.
I’m sure when the decision finally comes, the handling fee will reflect the immense effort of… letting it sit in the queue for a month.
Modern publishing: pay to wait.
@brasil247.bsky.social
da uma conferida lah nesse abuso de ChatGPT
da uma conferida lah nesse abuso de ChatGPT
November 20, 2025 at 4:45 PM
@brasil247.bsky.social
da uma conferida lah nesse abuso de ChatGPT
da uma conferida lah nesse abuso de ChatGPT
Reposted by Pedro Friedmann Angeli
🔓Don't miss this #OpenAccess review from @dbkonrad.bsky.social & co. at @univie.ac.at & @lmumuenchen.bsky.social, part of our New Talent collection providing their perspective on cysteine-reactive activity-based probes #orgchem #chembio
Check it out in full here🔽
Check it out in full here🔽
A perspective on cysteine-reactive activity-based probes
Activity-based protein profiling (ABPP) is a powerful method to investigate protein function, identify protein targets and determine the mechanisms-of-action of chemical probes as well as small…
pubs.rsc.org
November 20, 2025 at 12:30 PM
🔓Don't miss this #OpenAccess review from @dbkonrad.bsky.social & co. at @univie.ac.at & @lmumuenchen.bsky.social, part of our New Talent collection providing their perspective on cysteine-reactive activity-based probes #orgchem #chembio
Check it out in full here🔽
Check it out in full here🔽
Dear reviewer its not really helpful if you list all the good things about us but you still reject the grant because you don't like the workplan
November 20, 2025 at 11:43 AM
Dear reviewer its not really helpful if you list all the good things about us but you still reject the grant because you don't like the workplan
Reposted by Pedro Friedmann Angeli
Excited to share our new study, led by @dellaVolpe_L, now out in @natcellbio.nature.com! Blocking #ferroptosis enhances human 🩸 stem cell expansion, with implications for transplantation and gene therapy. www.nature.com/articles/s41...
November 18, 2025 at 5:49 PM
Excited to share our new study, led by @dellaVolpe_L, now out in @natcellbio.nature.com! Blocking #ferroptosis enhances human 🩸 stem cell expansion, with implications for transplantation and gene therapy. www.nature.com/articles/s41...
Reposted by Pedro Friedmann Angeli
calling "Acetylysine" the 21st amino acid is a declaration of war
October 24, 2025 at 6:38 PM
calling "Acetylysine" the 21st amino acid is a declaration of war
Reposted by Pedro Friedmann Angeli
We are delighted to announce our #HighlyCited2025 researchers: Ronny Thomale, @angelifriedmann.bsky.social , Georg Gasteiger, @dominicgrun.bsky.social, and Christoph Wanner. Congratulations!
➡️ www.uni-wuerzburg.de/en/news-and-...
➡️ www.uni-wuerzburg.de/en/news-and-...
November 12, 2025 at 9:19 AM
We are delighted to announce our #HighlyCited2025 researchers: Ronny Thomale, @angelifriedmann.bsky.social , Georg Gasteiger, @dominicgrun.bsky.social, and Christoph Wanner. Congratulations!
➡️ www.uni-wuerzburg.de/en/news-and-...
➡️ www.uni-wuerzburg.de/en/news-and-...
Reposted by Pedro Friedmann Angeli
The review by Banani, Lee, Hyman & Rosen (NRMCB 2017) www.nature.com/articles/nrm... on biomolecular condensates has >6000 citations. It…
1. Introduced a broad definition of “biomolecular condensates,” promoting acceptance that a unifying mechanism may underlie all membrane-less compartments.
1. Introduced a broad definition of “biomolecular condensates,” promoting acceptance that a unifying mechanism may underlie all membrane-less compartments.
Biomolecular condensates: organizers of cellular biochemistry - Nature Reviews Molecular Cell Biology
In addition to membrane-bound organelles, eukaryotic cells feature various membraneless compartments, including the centrosome, the nucleolus and various granules. Many of these compartments form thro...
www.nature.com
November 17, 2025 at 7:24 AM
The review by Banani, Lee, Hyman & Rosen (NRMCB 2017) www.nature.com/articles/nrm... on biomolecular condensates has >6000 citations. It…
1. Introduced a broad definition of “biomolecular condensates,” promoting acceptance that a unifying mechanism may underlie all membrane-less compartments.
1. Introduced a broad definition of “biomolecular condensates,” promoting acceptance that a unifying mechanism may underlie all membrane-less compartments.
Kids today will never know the pain of waking up early on Saturday, running to the TV for your favourite cartoon…
…only to realise it’s a repeat you already watched five times 😭📺
Streaming killed a very specific kind of character building experience
…only to realise it’s a repeat you already watched five times 😭📺
Streaming killed a very specific kind of character building experience
November 15, 2025 at 7:38 AM
Kids today will never know the pain of waking up early on Saturday, running to the TV for your favourite cartoon…
…only to realise it’s a repeat you already watched five times 😭📺
Streaming killed a very specific kind of character building experience
…only to realise it’s a repeat you already watched five times 😭📺
Streaming killed a very specific kind of character building experience
Reposted by Pedro Friedmann Angeli
Billionaires are more publicly involved in politics than ever—and Americans aren’t loving it.
Americans Want Billionaires Out Of Politics—And Think They’re A Threat To Democracy, Poll Shows
Billionaires are more publicly involved in politics than ever—and Americans aren’t loving it.
www.forbes.com
November 14, 2025 at 3:40 PM
Billionaires are more publicly involved in politics than ever—and Americans aren’t loving it.
Reposted by Pedro Friedmann Angeli
1/ It is no secret that I view the unchecked rise of liquid–liquid phase separation (LLPS) in biology as a profound distortion of molecular biology. It conflicts with its principles, it is logically incompatible with them, and the claims made in its name have been, with rare exceptions,...
–>2
–>2
November 14, 2025 at 8:27 AM
1/ It is no secret that I view the unchecked rise of liquid–liquid phase separation (LLPS) in biology as a profound distortion of molecular biology. It conflicts with its principles, it is logically incompatible with them, and the claims made in its name have been, with rare exceptions,...
–>2
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Every single time I apply with a colleague to a bilateral grant that involves the #CNPq 🇧🇷is a chance for one its reviewers to tell me how I have a mediocre scientific carreer - not sure why the personal swings but this is anything but professional 🧐
November 14, 2025 at 5:27 AM
Every single time I apply with a colleague to a bilateral grant that involves the #CNPq 🇧🇷is a chance for one its reviewers to tell me how I have a mediocre scientific carreer - not sure why the personal swings but this is anything but professional 🧐
🚨We have just launched a search to fill a new Jr group leader position!🚨
Great conditions to kickstart your own independent carreer - happy to answer any questions you might have.
please spread the word and repost!
www.uni-wuerzburg.de/en/rvz/jobs-...
Great conditions to kickstart your own independent carreer - happy to answer any questions you might have.
please spread the word and repost!
www.uni-wuerzburg.de/en/rvz/jobs-...
Job Offers - Rudolf Virchow Center for Integrative and Translational Bioimaging
www.uni-wuerzburg.de
November 12, 2025 at 3:13 PM
🚨We have just launched a search to fill a new Jr group leader position!🚨
Great conditions to kickstart your own independent carreer - happy to answer any questions you might have.
please spread the word and repost!
www.uni-wuerzburg.de/en/rvz/jobs-...
Great conditions to kickstart your own independent carreer - happy to answer any questions you might have.
please spread the word and repost!
www.uni-wuerzburg.de/en/rvz/jobs-...
Reposted by Pedro Friedmann Angeli
957 proposals were submitted in the latest round of ERC Synergy applications. They expect to fund 50 which means around 5% success rate. This is really not sustainable and a lot of people are likely avoiding doing this knowing how poor the chances are.
erc.europa.eu/news-events/...
erc.europa.eu/news-events/...
Applications for ERC Synergy Grants 2026: Facts and figures
The ERC Synergy Grants 2026 call closed for applications on 5 November 2025. These are the preliminary data on the submitted proposals:
erc.europa.eu
November 11, 2025 at 1:22 PM
957 proposals were submitted in the latest round of ERC Synergy applications. They expect to fund 50 which means around 5% success rate. This is really not sustainable and a lot of people are likely avoiding doing this knowing how poor the chances are.
erc.europa.eu/news-events/...
erc.europa.eu/news-events/...
Reposted by Pedro Friedmann Angeli
We have a post-doctoral fellow position in our laboratory. Please spread the news and encourage applications. Thank you!
vcujobs.com/jobs/post-do...
vcujobs.com/jobs/post-do...
Post-Doctoral Fellow - Department of Cellular, Molecular, and Genetic Medicine - MCV Main Campus, Virginia, United States
Advertising Summary: Virginia Commonwealth University (VCU) School of Medicine is a premier academic medical center located in the heart of Richmond. Accounting for almost half of VCU’s sponsored rese...
vcujobs.com
November 11, 2025 at 2:23 PM
We have a post-doctoral fellow position in our laboratory. Please spread the news and encourage applications. Thank you!
vcujobs.com/jobs/post-do...
vcujobs.com/jobs/post-do...
Reposted by Pedro Friedmann Angeli
Excited to share our work @nature.com! Postdoc @mariopalma.bsky.social, with major contributions from @retickerflynn.bsky.social and collaborators, discovered melanoma cells in lymph nodes gain a targetable FSP1 dependency that limits progression. #TeamFSP1
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Lymph node environment drives FSP1 targetability in metastasizing melanoma | Nature
www.nature.com
November 5, 2025 at 4:11 PM
Excited to share our work @nature.com! Postdoc @mariopalma.bsky.social, with major contributions from @retickerflynn.bsky.social and collaborators, discovered melanoma cells in lymph nodes gain a targetable FSP1 dependency that limits progression. #TeamFSP1
www.nature.com/articles/s41...
www.nature.com/articles/s41...
pubs.acs.org/doi/abs/10.1...
Congrats @theprattgroup.bsky.social for this thought provocative study. Still some unexpected observations in the autoxidation of lpids 👀
Congrats @theprattgroup.bsky.social for this thought provocative study. Still some unexpected observations in the autoxidation of lpids 👀
Intramolecular Hydrogen Atom Transfer Enables Hydroperoxyl Radical Formation during the Peroxidation of Unsaturated Lipids
Lipid peroxidation (autoxidation) is among the most well-studied free radical chain reactions and drives a cell death modality (ferroptosis) implicated in neurodegeneration and the damage resulting fr...
pubs.acs.org
November 1, 2025 at 10:25 PM
pubs.acs.org/doi/abs/10.1...
Congrats @theprattgroup.bsky.social for this thought provocative study. Still some unexpected observations in the autoxidation of lpids 👀
Congrats @theprattgroup.bsky.social for this thought provocative study. Still some unexpected observations in the autoxidation of lpids 👀
Reposted by Pedro Friedmann Angeli
Reposted by Pedro Friedmann Angeli
calling "Acetylysine" the 21st amino acid is a declaration of war
October 24, 2025 at 6:38 PM
calling "Acetylysine" the 21st amino acid is a declaration of war