Massimo Gadina
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massimogg.bsky.social
Massimo Gadina
@massimogg.bsky.social
120 followers 210 following 64 posts
Cytokines-JAKs-JAK inhibitors, Immunologist, mentor. Vespa (1961) 🛵 owner. Runner, AC Milan 🔴⚫️ fan. Opinion are solely mine.
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Reposted by Massimo Gadina
#Medsky🧪 #IDSky #oncosky #immunosky #pharmsky #publichealth #Ruxolitinib has shown promise for treating some symptoms of #LongCOVID by targeting the persistent, low-grade inflammation that characterizes the condition. As a Janus kinase (JAK) inhibitor,
Reposted by Massimo Gadina
@biorxivpreprint.bsky.social IL-36 upregulates type-I IFN responses in systemic #lupus erythematosus by promoting the accumulation of self-nucleic acids
www.biorxiv.org/content/10.1... @kingscollegelondon.bsky.social
Friday Night in San Francisco.
Al Di Meola, John McLaughlin, Paco de Lucia
en.wikipedia.org
Walked into COSTCO, for few things…. Walked out with a Novavax COVID shot! Not bad!
#vaccines
I think this piece should be read by many of my colleagues (senior and junior as well). Maybe somewhat satirical but a very on-point analysis nonetheless. #ImmunoSky

The Man Who Refused a Nobel Prize That He Never Won www.medpagetoday.com/opinion/seco...
Opinion | The Man Who Refused a Nobel Prize That He Never Won
Rethinking the scientific awards system
www.medpagetoday.com
Excellent analysis!
Vaccination: Risks and Benefits

Driving is important for our jobs and lifestyles, and the risk is quite low. So is vaccination.

www.nejm.org/doi/full/10....
Very accurate quote seen on a wall at the #Moomin museum in Tampere.
Reposted by Massimo Gadina
Equal Safety of JAK Inhibitors and TNF Inhibitors

JAMA has published a systematic review and meta-analysis of head-to-head studies showing there was no meaningful difference in safety events observed when taking either JAKi vs TNFi therapies for the treatment of IMIDs.

rheumnow.com/news/equal-s...
Excellent course/meeting. Great line up pf speakers and presenters. Consider attending!
#ImmunoSky
Registration deadline extended!

Registration for the FOCIS European Advanced Course now closes Sept 28!
Join leading global experts for 5 days of cutting-edge immunology — from molecular insights to clinical applications.

🚨 Register: zurl.co/bJ0Hk
RSV vaccine…. Done!
Vaccines save lives!!
#vaccine
Reposted by Massimo Gadina
Excited for support to uncover mechanisms of #primaryimmunedeficiencies #inbornerrorsofimmunity with friends @bogunoviclab.bsky.social and Josh Milner
When rare and undiagnosed conditions feel hopeless, science can unlock answers. Thanks to a new $12.4M NIH grant, WashU Medicine’s Megan Cooper, MD, deepens her work studying genetic causes to better diagnose and treat children with rare immune disorders medicine.washu.edu/news/researc...
Research explores genetics underlying immune system disorders | WashU Medicine
A $12 million NIH grant awarded to Megan Cooper, MD, PhD, will support the effort to understand and diagnose immune deficiencies.
medicine.washu.edu
Reposted by Massimo Gadina
"A respected network of hospitals and cancer centers is halting enrollment in clinical trials for children with brain cancer after the federal government said it would no longer provide funding to the group." www.nytimes.com/2025/08/28/w...
Pediatric Brain Cancer Trial Group to Be Phased Out
www.nytimes.com
Reposted by Massimo Gadina
(MotorTrend) Hey TOYOTA! Anyone home? It appears that NO ONE IS HOME if you are contributing $$ to Election-Denying GOP officials. GET SMART, YOU GUYS. LOOK AT THE POLLS. Trump & Co. are DOWN. And WE WILL WALK AWAY FROM YOU. Get smart, think it over, & CHANGE.

www.motortrend.com/news/toyota-...
Toyota Resumes Donations to Election-Objecting Republicans, Reigniting Controversy
Toyota is again contributing to controversial elected officials who questioned the results of the 2020 election, six months after pausing over backlash.
www.motortrend.com
Excellent course. Consider attending!!
📃 Check out the FOCIS European Advanced Course Preliminary Program. Join global experts for 5 days of cutting-edge immunology - from molecular mechanisms to clinical trials.

📃 Preliminary Program: zurl.co/S1pN6
🚨 Register before Sept 15: zurl.co/bJ0Hk
Reposted by Massimo Gadina
📃 Check out the FOCIS European Advanced Course Preliminary Program. Join global experts for 5 days of cutting-edge immunology - from molecular mechanisms to clinical trials.

📃 Preliminary Program: zurl.co/S1pN6
🚨 Register before Sept 15: zurl.co/bJ0Hk
Reposted by Massimo Gadina
TYK2 inhibition enhances Treg differentiation and function while preventing Th1 and Th17 differentiation
@cp-cellrepmed.bsky.social
@mklevings.bsky.social
cell.com/cell-reports...
Reposted by Massimo Gadina
one small consolation of being a 60+ year old investigator is the ability to submit to 𝘔𝘈𝘛𝘜𝘙𝘌 family journals — sure they’re low impact (for our knees) but they have an early bird special if you submit between 4:00 and 5:30 on weekdays
KC and the Overcast band
Supercool work!
Expanding the cytokine receptor alphabet reprograms T cells into diverse states @natmicrobiol.nature.com #GarciaLab @xrtcell.bsky.social
www.nature.com/articles/s41...
Reposted by Massimo Gadina
JAK2V617F neutrophils evade homeostatic clearance and accumulate in MPN owing to JAK2-STAT5–dependent upregulation of CD24. buff.ly/eujxmx2 #hemesky