#MarieCurieActions #MSCA #DoctoralNetworks #HorizonEurope #H2020 #ResearchImpactEU #IntegratedStressResponse #Autoimmunediseases #Dendriticcells
October 17, 2025 at 10:11 AM
This research letter provides a proof of concept that the pharmacological or genetic inhibition of mTOR sensitizes T-cell acute lymphoblastic leukemia cells to #Venetoclax via the sustained activation of #IntegratedStressResponse. #medsky
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
October 14, 2025 at 10:30 PM
This research letter provides a proof of concept that the pharmacological or genetic inhibition of mTOR sensitizes T-cell acute lymphoblastic leukemia cells to #Venetoclax via the sustained activation of #IntegratedStressResponse. #medsky
#OpenAccess: doi.org/10.1038/s413...
#OpenAccess: doi.org/10.1038/s413...
Have you ever wondered what are the mediators and effects of mitohormesis in organisms? In our review, we explore the unexpected path of mitochondrial stress to systemic benefits. 🔥 #mitochondria #mitohormesis #integratedstressresponse @ucberkeleyofficial.bsky.social
Mammalian #mitohormesis:
Amanda Gunawan, Irene Liparulo and Andreas Stahl review the winding path from mitochondrial stressors to organismal benefits
www.embopress.org/doi/full/10....
Amanda Gunawan, Irene Liparulo and Andreas Stahl review the winding path from mitochondrial stressors to organismal benefits
www.embopress.org/doi/full/10....
September 11, 2025 at 3:31 PM
Have you ever wondered what are the mediators and effects of mitohormesis in organisms? In our review, we explore the unexpected path of mitochondrial stress to systemic benefits. 🔥 #mitochondria #mitohormesis #integratedstressresponse @ucberkeleyofficial.bsky.social
Online today: Convergent activation of the #IntegratedStressResponse and ER–mitochondria uncoupling in VAPB-associated #AmyotrophicLateralSclerosis
By C. Landry, H. Miranda & colleagues at Case Western Reserve University
➡️ doi.org/10.1038/s443...
By C. Landry, H. Miranda & colleagues at Case Western Reserve University
➡️ doi.org/10.1038/s443...
August 5, 2025 at 2:07 PM
Online today: Convergent activation of the #IntegratedStressResponse and ER–mitochondria uncoupling in VAPB-associated #AmyotrophicLateralSclerosis
By C. Landry, H. Miranda & colleagues at Case Western Reserve University
➡️ doi.org/10.1038/s443...
By C. Landry, H. Miranda & colleagues at Case Western Reserve University
➡️ doi.org/10.1038/s443...
How is #Proteoglycan #Glycosaminoglycan accumulated in #ThoracicAorticAneurysm?😎
#AortaEd
An overactivation of #HexosamineBiosyntheticPathway-GAG-#IntegratedStressResponse #ERStress PERK eIF2α ATF4 cascade
@jorgeoller.bsky.social bioRxiv 2024
www.biorxiv.org/content/10.1...
#AortaEd
An overactivation of #HexosamineBiosyntheticPathway-GAG-#IntegratedStressResponse #ERStress PERK eIF2α ATF4 cascade
@jorgeoller.bsky.social bioRxiv 2024
www.biorxiv.org/content/10.1...
May 10, 2025 at 11:49 AM
How is #Proteoglycan #Glycosaminoglycan accumulated in #ThoracicAorticAneurysm?😎
#AortaEd
An overactivation of #HexosamineBiosyntheticPathway-GAG-#IntegratedStressResponse #ERStress PERK eIF2α ATF4 cascade
@jorgeoller.bsky.social bioRxiv 2024
www.biorxiv.org/content/10.1...
#AortaEd
An overactivation of #HexosamineBiosyntheticPathway-GAG-#IntegratedStressResponse #ERStress PERK eIF2α ATF4 cascade
@jorgeoller.bsky.social bioRxiv 2024
www.biorxiv.org/content/10.1...
#HappyResearcher #Immunology #IntegratedStressResponse #DendriticCells #SLE #SAVI #ISR #MarieCurieActions #MSCA #DoctoralNetworks #HorizonEurope (7/7)
March 13, 2025 at 2:38 PM
Honored to be working on the Characterization of rare gene variants affecting the Integrated Stress Response in dendritic cells and interferonopathies at @ciml.bsky.social in P. Pierre’s lab.
And grateful to be part of the @immerge.bsky.social program!
#ISR #IntegratedStressResponse #SAVI #SLE
And grateful to be part of the @immerge.bsky.social program!
#ISR #IntegratedStressResponse #SAVI #SLE
🔬 Meet the Researchers Behind IMMERGE! 🔬
This week: @angelopilotti.bsky.social & Dr. Pierre from @cnrs.fr!
Angelo will study the functional impact of EIF2AK mutants in dendritic cells & interferonopathies🧬👨🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #DCs #Interferonopathies
This week: @angelopilotti.bsky.social & Dr. Pierre from @cnrs.fr!
Angelo will study the functional impact of EIF2AK mutants in dendritic cells & interferonopathies🧬👨🔬
Stay tuned for more IMMERGE scientists! 🚀
#IMMERGE #MSCA #IEI #DCs #Interferonopathies
March 4, 2025 at 8:23 PM
Honored to be working on the Characterization of rare gene variants affecting the Integrated Stress Response in dendritic cells and interferonopathies at @ciml.bsky.social in P. Pierre’s lab.
And grateful to be part of the @immerge.bsky.social program!
#ISR #IntegratedStressResponse #SAVI #SLE
And grateful to be part of the @immerge.bsky.social program!
#ISR #IntegratedStressResponse #SAVI #SLE
🙋 Are you studying the Unfolded Protein Response (UPR) and/or the Integrated Stress Response (ISR)?
👇🏻 Let’s all gather here!
Thank you @profmarciniak.bsky.social!
#UPR #ISR #UnfoldedProteinResponse #IntegratedStressResponse
👇🏻 Let’s all gather here!
Thank you @profmarciniak.bsky.social!
#UPR #ISR #UnfoldedProteinResponse #IntegratedStressResponse
November 24, 2024 at 1:29 PM
🙋 Are you studying the Unfolded Protein Response (UPR) and/or the Integrated Stress Response (ISR)?
👇🏻 Let’s all gather here!
Thank you @profmarciniak.bsky.social!
#UPR #ISR #UnfoldedProteinResponse #IntegratedStressResponse
👇🏻 Let’s all gather here!
Thank you @profmarciniak.bsky.social!
#UPR #ISR #UnfoldedProteinResponse #IntegratedStressResponse