Zechner Lab
@zechnerlab.bsky.social
Research group at SISSA / Trieste. Interested in stochastic processes in biology & biophysics. Posts by C. Zechner.
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We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28!
www.cam.ac.uk/jobs/univers...
www.cam.ac.uk/jobs/univers...
University Assistant/Associate Professor in Control Theory and Systems Biology
Applications are invited for a University Assistant/Associate Professorship in the broad area of Control Theory and Systems Biology. The successful candidate will join the Control Group
www.cam.ac.uk
December 3, 2025 at 12:19 PM
We are opening a FACULTY POSITION (tenure track, permanent) in the University of Cambridge at the interface of control and biology, interpreted broadly. Theorists and wet lab quantitative biologists with backgrounds in control, EE, applied math, ... apply by Jan 28!
www.cam.ac.uk/jobs/univers...
www.cam.ac.uk/jobs/univers...
Reposted by Zechner Lab
I am honored and proud to work with my amazing group @mpi-cbg.de and @csbdresden.bsky.social 🥰 🧬. Thanks to all my colleagues for the wonderful scientific environment. And thank you @kboes.bsky.social for preparing this superb video! 🤩
Watch this video about the work of the research group of @agnestoth.bsky.social @mpi-cbg.de & @csbdresden.bsky.social. Agnes and her group work on protein plasticity and evolution. For her work, Agnes recently received the Schering Young Investigator Award 2025! youtu.be/lEpvGu3J63M?...
Protein plasticity and evolution: The research group of Agnes Toth-Petroczy at MPI-CBG
YouTube video by MPI-CBG
youtu.be
December 1, 2025 at 9:17 AM
I am honored and proud to work with my amazing group @mpi-cbg.de and @csbdresden.bsky.social 🥰 🧬. Thanks to all my colleagues for the wonderful scientific environment. And thank you @kboes.bsky.social for preparing this superb video! 🤩
Reposted by Zechner Lab
The most precious commodity you have is your attention. You don’t have to waste it on poor-faith debates or arguments with strangers if you don’t think they’ll be productive. You can prioritize the things that matter to you and make your life richer.
November 30, 2025 at 8:00 PM
The most precious commodity you have is your attention. You don’t have to waste it on poor-faith debates or arguments with strangers if you don’t think they’ll be productive. You can prioritize the things that matter to you and make your life richer.
Reposted by Zechner Lab
I’m very excited to start this project — it brings together ideas that matured over many years and opens a long-term path for innovation in RNA modelling. 🍾 🧬
🎉Our group has been awarded a prestigious #FIS grant! #RNAScale - Exploring RNA Dynamics across Scales: From Base Pairs to Viral Genomes 👉 www.bussilab.org/fis3
We will soon open postdoctoral positions across several components of the project! An expression-of-interest form is already online.
We will soon open postdoctoral positions across several components of the project! An expression-of-interest form is already online.
RNAScale
Exploring RNA Dynamics across Scales
www.bussilab.org
November 28, 2025 at 1:36 PM
I’m very excited to start this project — it brings together ideas that matured over many years and opens a long-term path for innovation in RNA modelling. 🍾 🧬
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One of our founding directors Anthony Hyman @hymanlab.bsky.social will become @embl.org Director General: www.mpi-cbg.de/news-outreac...
November 27, 2025 at 1:20 PM
One of our founding directors Anthony Hyman @hymanlab.bsky.social will become @embl.org Director General: www.mpi-cbg.de/news-outreac...
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Wonderful to see the beautiful preprint from Sabate et al now published - TADs are also dynamic structures in human cells, with remarkably similar parameters between mESCs and HCT116 cells
www.nature.com/articles/s41...
www.nature.com/articles/s41...
November 15, 2025 at 5:24 PM
Wonderful to see the beautiful preprint from Sabate et al now published - TADs are also dynamic structures in human cells, with remarkably similar parameters between mESCs and HCT116 cells
www.nature.com/articles/s41...
www.nature.com/articles/s41...
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Two 2-year postdoc positions in my theory group — for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176
#biophysics
#biophysics
Postdoc in Theoretical Biophysics
Two postdoc positions (each for two years, funded by Amidex Foundation) are available in theoretical biophysics within the theory group at DyNaMo (Aix-Marseille University).
euraxess.ec.europa.eu
October 27, 2025 at 4:19 PM
Two 2-year postdoc positions in my theory group — for studying the interplay between metabolism and morphogenesis at the edge of the Calanques and the Mediterranean. More information can be found on: euraxess.ec.europa.eu/jobs/381176
#biophysics
#biophysics
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Really excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication.
www.biorxiv.org/content/10.1...
A🧵👇
www.biorxiv.org/content/10.1...
A🧵👇
September 24, 2025 at 9:45 PM
Really excited to share our latest work led by @mattiaubertini.bsky.social and @nesslfy.bsky.social: we report that cohesin loop extrusion creates rare but long-lived encounters between genomic sequences which underlie efficient enhancer-promoter communication.
www.biorxiv.org/content/10.1...
A🧵👇
www.biorxiv.org/content/10.1...
A🧵👇
Reposted by Zechner Lab
Thanks a lot to @elisecutts.bsky.social for nicely highlighting and putting in context our article! It was very interesting to discuss together, notably about the analogies between the emergence of order in Hydra and other physical phenomena.
Hydra are ~basically~ immortal.
Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads!
This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
Shred 50 of the lil guys to bits and pack their cells in a blob, and that blob will grow into a new Hydra... albeit with a few extra heads!
This week's post is a Q&A @anaisbailles.bsky.social @mpi-cbg.de about the physics of how Hydra coax order from chaos.🧪⚛️
Hydra are a cosmos in a cuvette
Anaïs Bailles on astrophysics and immortal animals
www.reviewertoo.com
September 12, 2025 at 1:56 PM
Thanks a lot to @elisecutts.bsky.social for nicely highlighting and putting in context our article! It was very interesting to discuss together, notably about the analogies between the emergence of order in Hydra and other physical phenomena.
Reposted by Zechner Lab
Great work! Congratulations you all & especially to
@carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...
@carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...
The Friday second try: After intense work, especially in the last year, this work is finally ready to be seen by the public. Led by @apramos.bsky.social and great collaboration with @carldmodes.bsky.social group especially @liormoneta.bsky.social : www.biorxiv.org/content/10.1...
The Optic cup is actively shape programmed by independently patterned apical forces
During morphogenesis, initially flat tissues often must transition into complex 3D shapes, reminiscent of shape-programmable systems in physics and engineering. One key question in developmental biolo...
www.biorxiv.org
August 22, 2025 at 2:13 PM
Great work! Congratulations you all & especially to
@carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...
@carldmodes.bsky.social who joined today after a lot of arm twisting by Caren...
Reposted by Zechner Lab
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 21, 2025 at 5:19 AM
Out today in @nature.com: Together with the Honigmann, Shevchenko, Drobot and Hof labs, we present a general workflow for imaging the localization and transport of individual lipids in cells and mapping their metabolism.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Zechner Lab
Our beautiful Hydra made the cover!!! 😍😍😍
An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de
Actin fibers in blue, nuclei in orange.
An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de
Actin fibers in blue, nuclei in orange.
August 13, 2025 at 8:51 AM
Our beautiful Hydra made the cover!!! 😍😍😍
An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de
Actin fibers in blue, nuclei in orange.
An experiment performed by Pavel Mejstrik with a HCR protocol by @giuliaserafini.bsky.social, @paveltomancak.bsky.social lab @mpi-cbg.de
Actin fibers in blue, nuclei in orange.
Reposted by Zechner Lab
Our first #Hydra paper. @anaisbailles.bsky.social all the way, with crucial theory contributions from Carl Modes and @zechnerlab.bsky.social Hydra maintenance by Heino Andreas and HCR by Giulia Serafini. Teamwork. Many thanks to the generous Hydra research community.
Very happy that the first article from my postdoc work in the Tomancak lab is now published @PNAS! www.pnas.org/doi/10.1073/.... We studied the self-organization of actin in aggregates made from Hydra cells. Thread below (1/9)
August 6, 2025 at 3:13 PM
Our first #Hydra paper. @anaisbailles.bsky.social all the way, with crucial theory contributions from Carl Modes and @zechnerlab.bsky.social Hydra maintenance by Heino Andreas and HCR by Giulia Serafini. Teamwork. Many thanks to the generous Hydra research community.
Reposted by Zechner Lab
Stretching the immortal Hydra. Publication by @paveltomancak.bsky.social group with Carl Modes @mpi-cbg.de & @zechnerlab.bsky.social shows how cells can create a new organism from scratch by coordinating their mechanical properties. @anaisbailles.bsky.social @pnas.org www.mpi-cbg.de/news-outreac...
Stretching the immortal Hydra
Dresden researchers show how cells can create a new organism from scratch by coordinating their mechanical properties.
www.mpi-cbg.de
August 5, 2025 at 12:45 PM
Stretching the immortal Hydra. Publication by @paveltomancak.bsky.social group with Carl Modes @mpi-cbg.de & @zechnerlab.bsky.social shows how cells can create a new organism from scratch by coordinating their mechanical properties. @anaisbailles.bsky.social @pnas.org www.mpi-cbg.de/news-outreac...
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Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Novel Research in Biological Artificial Intelligence
Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.
www.mpi-cbg.de
June 26, 2025 at 11:26 AM
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Reposted by Zechner Lab
We are searching for an AI researcher in lab automation, statistical ML and (theoretical) physics AI for bio/med. Expression of interest and nominations welcome!!!
Novel Research in Biological Artificial Intelligence: Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence @mpi-cbg.de and @csbdresden.bsky.social. More information: www.mpi-cbg.de/news-outreac...
Novel Research in Biological Artificial Intelligence
Expressions of interest and nominations for a Max Planck Director to lead research in the field of Biological Artificial Intelligence.
www.mpi-cbg.de
June 26, 2025 at 9:10 PM
We are searching for an AI researcher in lab automation, statistical ML and (theoretical) physics AI for bio/med. Expression of interest and nominations welcome!!!
Reposted by Zechner Lab
We are looking for a research assistant to join our lab and support ongoing projects with genome engineering in mouse embryonic stem cells! Please get in touch if you are interested.
www.fmi.ch/education-ca...
www.fmi.ch/education-ca...
Friedrich Miescher Institute, open position
Friedrich Miescher Institute, open position
www.fmi.ch
June 26, 2025 at 3:04 PM
We are looking for a research assistant to join our lab and support ongoing projects with genome engineering in mouse embryonic stem cells! Please get in touch if you are interested.
www.fmi.ch/education-ca...
www.fmi.ch/education-ca...
Reposted by Zechner Lab
(1/n) Thread @matteomazzocca.bsky.social @domenicnarducci.bsky.social Simon Grosse-Holz @jessematthias.bsky.social preprint
Q: how does chromatin move?
Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...
Q: how does chromatin move?
Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...
May 15, 2025 at 12:37 PM
(1/n) Thread @matteomazzocca.bsky.social @domenicnarducci.bsky.social Simon Grosse-Holz @jessematthias.bsky.social preprint
Q: how does chromatin move?
Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...
Q: how does chromatin move?
Using MINFLUX, SPT & SRLCI, we track chromatin dynamics across 7 orders of magnitude in time to provide answers www.biorxiv.org/content/10.1...
Many congratulations to Anne for defending her PhD this week…excellent results and presentation! We wish you all the best for your future career!
March 28, 2025 at 8:51 AM
Many congratulations to Anne for defending her PhD this week…excellent results and presentation! We wish you all the best for your future career!
Reposted by Zechner Lab
We are finalizing the program of the @cecamevents.bsky.social RNA modelling across scales www.cecam.org/workshop-det... at SISSA, Trieste, Italy, May 19-22. Please note that we still have a few slots for in person attendance. We will accept applications for the next few weeks, until fully booked!
March 27, 2025 at 5:15 PM
We are finalizing the program of the @cecamevents.bsky.social RNA modelling across scales www.cecam.org/workshop-det... at SISSA, Trieste, Italy, May 19-22. Please note that we still have a few slots for in person attendance. We will accept applications for the next few weeks, until fully booked!
Reposted by Zechner Lab
Come to #Prague for #Woodstock2025. What is it? A scientific conference unlike any other. Think #BurningMan or #MusicFestival but #science themed. It'll have two parts - decentralised sessions spread in #Prague (sightsee as you move around) & #campsite event to wrap it up (1/7)
March 2, 2025 at 11:52 AM
Come to #Prague for #Woodstock2025. What is it? A scientific conference unlike any other. Think #BurningMan or #MusicFestival but #science themed. It'll have two parts - decentralised sessions spread in #Prague (sightsee as you move around) & #campsite event to wrap it up (1/7)
Reposted by Zechner Lab
"Cacio e pepe" physics: In arxiv.org/abs/2501.00536v1, eight Italian scientists from the Max Planck Institute for the Physics of Complex Systems explain the physics behind a perfect dish of "cacio e pepe" and how to eschew the dreaded "mozzarella phase" - work featured @nytimes.com.
January 29, 2025 at 8:50 PM
"Cacio e pepe" physics: In arxiv.org/abs/2501.00536v1, eight Italian scientists from the Max Planck Institute for the Physics of Complex Systems explain the physics behind a perfect dish of "cacio e pepe" and how to eschew the dreaded "mozzarella phase" - work featured @nytimes.com.
Congratulations Tommaso for an excellent PhD defense! Very well done!
February 13, 2025 at 4:56 PM
Congratulations Tommaso for an excellent PhD defense! Very well done!
Excited to share our new work with Frank Jülicher on noise control & concentration buffering in intracellular condensates! There has been confusion about these concepts, which we aim to address in this paper.
www.cell.com/cell-systems...
www.cell.com/cell-systems...
February 12, 2025 at 8:47 AM
Excited to share our new work with Frank Jülicher on noise control & concentration buffering in intracellular condensates! There has been confusion about these concepts, which we aim to address in this paper.
www.cell.com/cell-systems...
www.cell.com/cell-systems...
Reposted by Zechner Lab
Starting the new season of seminars in Molecular and Statistical Biophysics at SISSA! Gareth Tribello today gave a talk with title “Reconnaissance Metadynamics Rides Again”
February 4, 2025 at 8:22 PM
Starting the new season of seminars in Molecular and Statistical Biophysics at SISSA! Gareth Tribello today gave a talk with title “Reconnaissance Metadynamics Rides Again”