@spapid.bsky.social
Reposted
When a mysterious deadly virus attacked the Four Corners region of the U.S., the assistance of Navajo elders proved invaluable in uncovering the cause. Read this story of resilience, wisdom and collaboration: asm.social/2Gn #NAHM2025
How Indigenous Knowledge Helped Solve a Mysterious Outbreak | ASM.org
When a mysterious deadly virus attacked the Four Corners region of the U.S., the assistance of Navajo elders proved invaluable in uncovering the cause.
asm.social
November 11, 2025 at 5:27 PM
When a mysterious deadly virus attacked the Four Corners region of the U.S., the assistance of Navajo elders proved invaluable in uncovering the cause. Read this story of resilience, wisdom and collaboration: asm.social/2Gn #NAHM2025
Reposted
A high-resolution digital map allows people to plan their routes along the ancient roads of the Roman Empire
go.nature.com/4nHZmoM
go.nature.com/4nHZmoM
‘Google Maps’ for Roman roads reveals vast extent of ancient network
Nature - A high-resolution digital map nearly doubles the known length of the ancient road network.
go.nature.com
November 9, 2025 at 10:08 AM
A high-resolution digital map allows people to plan their routes along the ancient roads of the Roman Empire
go.nature.com/4nHZmoM
go.nature.com/4nHZmoM
Reposted
Revising Sepsis Definitions to Better Target and Tailor Sepsis Care
Revising Sepsis Definitions to Better Target and Tailor Sepsis Care
How we define sepsis has significant implications for clinical care, quality improvement, and regulatory policies.
academic.oup.com
July 26, 2025 at 12:41 PM
Revising Sepsis Definitions to Better Target and Tailor Sepsis Care
Reposted
PODCAST DROP!
This week Callum & Alyssa talk to Jeremy Day about Cryptococcus! Overview & diagnostics this week, treatment next week. Enjoy!
podcasts.apple.com/gb/podcast/i...
#idsky #idtwitter #microsky #infection #fungi
This week Callum & Alyssa talk to Jeremy Day about Cryptococcus! Overview & diagnostics this week, treatment next week. Enjoy!
podcasts.apple.com/gb/podcast/i...
#idsky #idtwitter #microsky #infection #fungi
113. The yeasts: Cryptococcus part 1, overview and diagnosis
Podcast Episode · ID:IOTS - Infectious Disease Insight Of Two Specialists · 07/07/2025 · 45m
podcasts.apple.com
July 7, 2025 at 6:30 AM
PODCAST DROP!
This week Callum & Alyssa talk to Jeremy Day about Cryptococcus! Overview & diagnostics this week, treatment next week. Enjoy!
podcasts.apple.com/gb/podcast/i...
#idsky #idtwitter #microsky #infection #fungi
This week Callum & Alyssa talk to Jeremy Day about Cryptococcus! Overview & diagnostics this week, treatment next week. Enjoy!
podcasts.apple.com/gb/podcast/i...
#idsky #idtwitter #microsky #infection #fungi
Reposted
We prescribe medication after medication to prevent serious heart events—and while these are needed, we often miss the simplest prevention measure: a flu shot. Vaccination is linked to ~50% fewer cardiovascular events in people with heart disease.
globalheartjournal.com
July 4, 2025 at 7:38 PM
We prescribe medication after medication to prevent serious heart events—and while these are needed, we often miss the simplest prevention measure: a flu shot. Vaccination is linked to ~50% fewer cardiovascular events in people with heart disease.
Reposted
before and after today’s glacier collapse that buried 90% of blatten, switzerland
May 28, 2025 at 10:01 PM
before and after today’s glacier collapse that buried 90% of blatten, switzerland
Reposted
Over 2,400 years ago, Thucydides noticed that survivors of a mysterious plague in Athens never got sick again. That observation sparked a journey through centuries of experiments, risky trials, and brilliant moments. Read more: historyofvaccines.org/blog/remarka...
The Remarkable Journey of Immunology
From an observation by Thucydides to the use of mRNA vaccines, immunology has come a long way.
historyofvaccines.org
May 23, 2025 at 9:06 PM
Over 2,400 years ago, Thucydides noticed that survivors of a mysterious plague in Athens never got sick again. That observation sparked a journey through centuries of experiments, risky trials, and brilliant moments. Read more: historyofvaccines.org/blog/remarka...
Reposted
Trump on imams: "I said, 'Do you want to die?' They said, 'We don't want to die.' I said, 'What about the 38 virgins?' They said, 'That's nonsense! We don't know anything about it.' And we won the state of Michigan."
May 1, 2025 at 4:53 PM
Trump on imams: "I said, 'Do you want to die?' They said, 'We don't want to die.' I said, 'What about the 38 virgins?' They said, 'That's nonsense! We don't know anything about it.' And we won the state of Michigan."
Reposted
Carl warned us 30 years ago:
April 26, 2025 at 2:48 PM
Carl warned us 30 years ago:
Reposted
1) A meta-analysis of RCTs of oral Abx for CAP found:
"oral antibiotic therapy had a beneficial effect on the risk of all-cause mortality (RR, 0.58; 95% CI, 0.35–0.96; P = 0.034)."
Which is pretty amazing, and parallels suggestive findings of bacteremia and endocarditis RCTs.
"oral antibiotic therapy had a beneficial effect on the risk of all-cause mortality (RR, 0.58; 95% CI, 0.35–0.96; P = 0.034)."
Which is pretty amazing, and parallels suggestive findings of bacteremia and endocarditis RCTs.
April 19, 2025 at 7:05 PM
1) A meta-analysis of RCTs of oral Abx for CAP found:
"oral antibiotic therapy had a beneficial effect on the risk of all-cause mortality (RR, 0.58; 95% CI, 0.35–0.96; P = 0.034)."
Which is pretty amazing, and parallels suggestive findings of bacteremia and endocarditis RCTs.
"oral antibiotic therapy had a beneficial effect on the risk of all-cause mortality (RR, 0.58; 95% CI, 0.35–0.96; P = 0.034)."
Which is pretty amazing, and parallels suggestive findings of bacteremia and endocarditis RCTs.
Reposted
2) For both CAP and SSTIs, several of the trials, including the one by the prodigious and amazing
@aurdinh.bsky.social, oral therapy was used up front, with no IV lead in!
Thanks again to Dr. Wong for doing the leg work to find these trials!
@aurdinh.bsky.social, oral therapy was used up front, with no IV lead in!
Thanks again to Dr. Wong for doing the leg work to find these trials!
April 19, 2025 at 7:05 PM
2) For both CAP and SSTIs, several of the trials, including the one by the prodigious and amazing
@aurdinh.bsky.social, oral therapy was used up front, with no IV lead in!
Thanks again to Dr. Wong for doing the leg work to find these trials!
@aurdinh.bsky.social, oral therapy was used up front, with no IV lead in!
Thanks again to Dr. Wong for doing the leg work to find these trials!
Reposted
How good are we at preventing HIV? The latest episode of Beyond Journal Club, a collaboration between @coreimpodcast.bsky.social and NEJM Group, takes a deep dive into the PURPOSE trials, which look at the use of long-acting lenacapavir as PrEP. 🎧 Listen now: nej.md/4lDlNf2
#MedSky #IDSky
#MedSky #IDSky
April 18, 2025 at 1:38 PM
How good are we at preventing HIV? The latest episode of Beyond Journal Club, a collaboration between @coreimpodcast.bsky.social and NEJM Group, takes a deep dive into the PURPOSE trials, which look at the use of long-acting lenacapavir as PrEP. 🎧 Listen now: nej.md/4lDlNf2
#MedSky #IDSky
#MedSky #IDSky
Reposted
We've greatly underestimated the role of the gut microbiome in fatty liver disease (MASLD). This open-access outstanding review @jclinical-invest.bsky.social is illuminating
www.jci.org/articles/vie...
www.jci.org/articles/vie...
April 6, 2025 at 4:50 PM
We've greatly underestimated the role of the gut microbiome in fatty liver disease (MASLD). This open-access outstanding review @jclinical-invest.bsky.social is illuminating
www.jci.org/articles/vie...
www.jci.org/articles/vie...
Reposted
Diagnosis of Prosthetic Joint Infection of Hips and Knees - One Size Does Not Fit All
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Diagnosis of Prosthetic Joint Infection of Hips and Knees - One Size Does Not Fit All
This study evaluated IDSA, ICM2018, and EBJIS criteria, finding IDSA most accurate for early PJI and knee infections, while ICM2018 and EBJIS were superior for delayed and late cases. Diagnostic approaches should consider infection timing and context.
doi.org
April 6, 2025 at 2:33 PM
Diagnosis of Prosthetic Joint Infection of Hips and Knees - One Size Does Not Fit All
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Reposted
Anyone who attended this year's #CROI2025 will tell you it was a very strange experience given the current political climate. Still, plenty of interesting studies -- here's a Really Rapid Review of selected highlights. #IDSky #HIVSky blogs.jwatch.org/hiv-id-obser...
Really Rapid Review: CROI 2025 San Francisco
Wow, that was an interesting conference — in ways both good and bad. The good part was the content, as the Conference on Retroviruses and Opportunistic Infections (CROI) is our leading HIV research co...
blogs.jwatch.org
March 22, 2025 at 10:55 AM
Anyone who attended this year's #CROI2025 will tell you it was a very strange experience given the current political climate. Still, plenty of interesting studies -- here's a Really Rapid Review of selected highlights. #IDSky #HIVSky blogs.jwatch.org/hiv-id-obser...
Reposted
I've reviewed 10 consumer-facing companies that are in the business of promoting longevity and healthspan
erictopol.substack.com/p/the-busine...
Open-access, in the new edition of Ground Truths
erictopol.substack.com/p/the-busine...
Open-access, in the new edition of Ground Truths
March 22, 2025 at 5:14 PM
I've reviewed 10 consumer-facing companies that are in the business of promoting longevity and healthspan
erictopol.substack.com/p/the-busine...
Open-access, in the new edition of Ground Truths
erictopol.substack.com/p/the-busine...
Open-access, in the new edition of Ground Truths
Reposted
Michael Lewis is one hell of a writer--here on the FDA, Balamuthia, and #RareDiseases... Proud mama moment, forgive me. Gift link: wapo.st/3DELV80 #MedicalMysteries #Balamuthia #GorgasCourse #FDA #DrugRepurposing
wapo.st
March 13, 2025 at 2:27 PM
Michael Lewis is one hell of a writer--here on the FDA, Balamuthia, and #RareDiseases... Proud mama moment, forgive me. Gift link: wapo.st/3DELV80 #MedicalMysteries #Balamuthia #GorgasCourse #FDA #DrugRepurposing
Reposted
February 22, 2025 at 6:20 PM
Reposted
Thoughtful challenge to 30 yrs of clinical practice. FQ ppx to prevent SBP in pts w/ cirrhosis based on low quality evidence and a/w ⬆️ resistant bacteria, longer hospitalizations, C diff, ⬆️ gut translocation due to microbiome disruption, and ⬆️ rates of recurrent SBP. academic.oup.com/cid/advance-...
Rethinking Antibiotic Prophylaxis for Spontaneous Bacterial Peritonitis in Patients with Cirrhosis: First, Do No Harm
Abstract. Antibiotic prophylaxis for spontaneous bacterial peritonitis (SBPPr) in patients with cirrhosis has been considered standard of care since the 19
academic.oup.com
February 8, 2025 at 2:38 PM
Thoughtful challenge to 30 yrs of clinical practice. FQ ppx to prevent SBP in pts w/ cirrhosis based on low quality evidence and a/w ⬆️ resistant bacteria, longer hospitalizations, C diff, ⬆️ gut translocation due to microbiome disruption, and ⬆️ rates of recurrent SBP. academic.oup.com/cid/advance-...
Reposted
New #LetsTalkID episode out! Paul Sax, MD, FIDSA, Varun Phadke, MD, and Daniel Minter, MD discuss CID's new series, "Clinical Dilemmas in Infectious Diseases," a guide through challenging clinical decisions in ID.
Available where you listen to podcasts. Transcript: www.idsociety.org/multimedia/p...
Available where you listen to podcasts. Transcript: www.idsociety.org/multimedia/p...
Exploring Clinical Dilemmas in Infectious Diseases
Paul Sax, MD, FIDSA, is joined by Varun Phadke, MD, and Daniel Minter, MD, co-creators of CID's new series, "Clinical Dilemmas in Infectious Diseases," which guides readers through challenging clinica...
www.idsociety.org
February 1, 2025 at 6:12 PM
New #LetsTalkID episode out! Paul Sax, MD, FIDSA, Varun Phadke, MD, and Daniel Minter, MD discuss CID's new series, "Clinical Dilemmas in Infectious Diseases," a guide through challenging clinical decisions in ID.
Available where you listen to podcasts. Transcript: www.idsociety.org/multimedia/p...
Available where you listen to podcasts. Transcript: www.idsociety.org/multimedia/p...
Reposted
I know there's huge concern about the material on the #CDC site that went dark last night.
For those looking for the #ACIP recommendations on vaccinations, that page is live here: www.cdc.gov/acip-recs/hc...
For those looking for the #ACIP recommendations on vaccinations, that page is live here: www.cdc.gov/acip-recs/hc...
Vaccine-Specific Recommendations
Access all vaccine-specific recommendations from ACIP.
www.cdc.gov
February 1, 2025 at 3:45 PM
I know there's huge concern about the material on the #CDC site that went dark last night.
For those looking for the #ACIP recommendations on vaccinations, that page is live here: www.cdc.gov/acip-recs/hc...
For those looking for the #ACIP recommendations on vaccinations, that page is live here: www.cdc.gov/acip-recs/hc...
Reposted
In CID, Nicholas A Turner, MD MHSc, and colleagues describe the natural history of C. difficile NAAT+/toxin- adults.
Natural History of Clostridioides difficile-related Disease Progression in the Two-Step Testing Era
buff.ly
January 30, 2025 at 5:01 PM
In CID, Nicholas A Turner, MD MHSc, and colleagues describe the natural history of C. difficile NAAT+/toxin- adults.
Reposted
Characteristics of clinics offering non-traditional Lyme disease therapies in Lyme endemic states of the US
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Characteristics of clinics offering non-traditional Lyme disease therapies in Lyme endemic states of the US
In this cross-sectional analysis, we analyzed 117 US clinics in Lyme endemic states that provide non-traditional care for Lyme disease. We found that unproven therapies are routinely offered, and some therapies raise safety concerns. The cost of care can be high, which may lead to significant out-of-pocket expenditures for patients.
buff.ly
January 26, 2025 at 3:12 PM
Characteristics of clinics offering non-traditional Lyme disease therapies in Lyme endemic states of the US
✅ Just Accepted
#IDSky
✅ Just Accepted
#IDSky
Reposted
ONE ANTIBIOTIC PK TABLE TO RULE THEM ALL
Absorption takes drug into blood from GI,
Vd spreads drug out to where bug calls home.
And after bacteria are doomed to die,
The drug’s eliminated on the porcelain throne
In the Land of Notion where this table doth lie…
#idSky #microsky #pharmsky #medsky
Absorption takes drug into blood from GI,
Vd spreads drug out to where bug calls home.
And after bacteria are doomed to die,
The drug’s eliminated on the porcelain throne
In the Land of Notion where this table doth lie…
#idSky #microsky #pharmsky #medsky
January 26, 2025 at 7:48 PM
Reposted
TOMORROW, Fri., Jan. 10 at 2 p.m. ET: learn about the new add-on code (G0545), which boosts hospital and inpatient evaluation and management services by $28.80 each time it’s used.
Register: https://buff.ly/40tBSu7
Register: https://buff.ly/40tBSu7
January 9, 2025 at 7:33 PM
TOMORROW, Fri., Jan. 10 at 2 p.m. ET: learn about the new add-on code (G0545), which boosts hospital and inpatient evaluation and management services by $28.80 each time it’s used.
Register: https://buff.ly/40tBSu7
Register: https://buff.ly/40tBSu7