Schmidt Lab Innsbruck
@schmidtlabibk.bsky.social
cell biologists and sphingolipid afficionados in the middle of the Alps
https://cellbiology.i-med.ac.at/research-groups/the-schmidt-laboratory/
Medical University of Innsbruck, Institute of Cell Biology
opinions are my own.
https://cellbiology.i-med.ac.at/research-groups/the-schmidt-laboratory/
Medical University of Innsbruck, Institute of Cell Biology
opinions are my own.
Reposted by Schmidt Lab Innsbruck
Für seinen Beitrag zum Verständnis der zellulären Kraftwerke (Mitochondrien) wurde Nikolaus Pfanner in die Accademia Nazionale dei Lincei, die nationale Akademie der Wissenschaften Italiens, aufgenommen. Zudem erhielt er die Walter Neupert-Medaille. ufr.link/auszeichnung-pfanner @cibss.bsky.social
December 2, 2025 at 12:24 PM
Für seinen Beitrag zum Verständnis der zellulären Kraftwerke (Mitochondrien) wurde Nikolaus Pfanner in die Accademia Nazionale dei Lincei, die nationale Akademie der Wissenschaften Italiens, aufgenommen. Zudem erhielt er die Walter Neupert-Medaille. ufr.link/auszeichnung-pfanner @cibss.bsky.social
Reposted by Schmidt Lab Innsbruck
Thrilled to share our latest work showing that the bridge lipid transport protein ATG2A transfers diacylglycerol (DAG), and some TAG/PA, from the ER to LDs, thereby recruiting DGAT2 to drive local TAG synthesis, promoting LD expansion while protecting ER membranes.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
ATG2A-mediated DAG transfer recruits DGAT2 for lipid droplet growth - Nature Structural & Molecular Biology
Elhan et al. show that ATG2A acts with DGAT2, the enzyme producing triacylglycerol (TAG), in lipid droplet growth. By delivering diacylglycerol to lipid droplets, ATG2A not only fuels TAG production b...
www.nature.com
November 17, 2025 at 10:57 PM
Thrilled to share our latest work showing that the bridge lipid transport protein ATG2A transfers diacylglycerol (DAG), and some TAG/PA, from the ER to LDs, thereby recruiting DGAT2 to drive local TAG synthesis, promoting LD expansion while protecting ER membranes.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Schmidt Lab Innsbruck
Such a worthy recipient. Maya is not only a great scientist but also a fantastic mentor and a rich source of inspiration.
🎉 Huge congrats to Maya Schuldiner from the Weizmann Institute (Israel) for the 🏅 Otto Warburg Medal 2026!
Her work on how proteins find their way to organelles and how these organelles talk to each other has reshaped how we think about cells 🧬✨
#OWM #WeizmannInstitute @elsevierconnect.bsky.social
Her work on how proteins find their way to organelles and how these organelles talk to each other has reshaped how we think about cells 🧬✨
#OWM #WeizmannInstitute @elsevierconnect.bsky.social
October 27, 2025 at 10:43 AM
Such a worthy recipient. Maya is not only a great scientist but also a fantastic mentor and a rich source of inspiration.
Reposted by Schmidt Lab Innsbruck
Quiescent cells stay alive by eating less. They downregulate amino acid transporters to match reduced demand. When this brake fails -> cell death & disease.
More info in our new paper 👇
More info in our new paper 👇
TXNIP mediates LAT1/SLC7A5 endocytosis to limit amino acid uptake in cells entering quiescence | The EMBO Journal www.embopress.org/doi/full/10....
TXNIP mediates LAT1/SLC7A5 endocytosis to limit amino acid uptake in cells entering quiescence | The EMBO Journal
imageimageIt remains unclear how cells reduce nutrient uptake in quiescence. This work shows
that the α-arrestin TXNIP couples reduced AKT signaling to endocytosis of the amino
acid transporter LAT1/S...
www.embopress.org
October 20, 2025 at 4:03 PM
Quiescent cells stay alive by eating less. They downregulate amino acid transporters to match reduced demand. When this brake fails -> cell death & disease.
More info in our new paper 👇
More info in our new paper 👇
Reposted by Schmidt Lab Innsbruck
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
October 15, 2025 at 6:33 AM
Finally, someone has solved a real problem with AI! No more having to take a paper in the format for a journal that rejected you, and reformat it for a new journal. Well done!! formatmypaper.com
Reposted by Schmidt Lab Innsbruck
GBM Lunch: July 16, 12:30
Speaker: Volker Haucke (@volkerhaucke-lab.bsky.social, @fmp-berlin.de)
Title: "Lipid control of membrane dynamics in health and disease"
Chair: Johannes Herrmann (RPTU)
Organized by GBM Study Group "Cellular Organelles"
gbm-online.de/gbm-lunch.html
#GBMLunch
Speaker: Volker Haucke (@volkerhaucke-lab.bsky.social, @fmp-berlin.de)
Title: "Lipid control of membrane dynamics in health and disease"
Chair: Johannes Herrmann (RPTU)
Organized by GBM Study Group "Cellular Organelles"
gbm-online.de/gbm-lunch.html
#GBMLunch
July 8, 2025 at 9:50 AM
GBM Lunch: July 16, 12:30
Speaker: Volker Haucke (@volkerhaucke-lab.bsky.social, @fmp-berlin.de)
Title: "Lipid control of membrane dynamics in health and disease"
Chair: Johannes Herrmann (RPTU)
Organized by GBM Study Group "Cellular Organelles"
gbm-online.de/gbm-lunch.html
#GBMLunch
Speaker: Volker Haucke (@volkerhaucke-lab.bsky.social, @fmp-berlin.de)
Title: "Lipid control of membrane dynamics in health and disease"
Chair: Johannes Herrmann (RPTU)
Organized by GBM Study Group "Cellular Organelles"
gbm-online.de/gbm-lunch.html
#GBMLunch
Reposted by Schmidt Lab Innsbruck
Just stumbled upon a German tongue-twister song by Bodo Wartke… about the sexiest cell organelle. Yes, endoplasmic reticulum - your moment has come.
youtube.com/shorts/EP5pd...
youtube.com/shorts/EP5pd...
Das endoplasmatische Retikulum
YouTube video by Bodo Wartke
youtube.com
June 7, 2025 at 9:54 AM
Just stumbled upon a German tongue-twister song by Bodo Wartke… about the sexiest cell organelle. Yes, endoplasmic reticulum - your moment has come.
youtube.com/shorts/EP5pd...
youtube.com/shorts/EP5pd...
Reposted by Schmidt Lab Innsbruck
Incredibly grateful to my mentors, lab members, and generous collaborators who continue to inspire our work. Thankful also to microbial cell surfaces and tomography, which continue to deliver the excitement everyday!
EMBO is delighted to announce that this year the EMBO Gold Medal is awarded to Tanmay Bharat @tbharat-lab.bsky.social @mrclmb.bsky.social and David Bikard @dbikard.bsky.social @pasteur.fr for their remarkable contributions to the #LifeSciences.
www.embo.org/press-releas...
#award 🧪
www.embo.org/press-releas...
#award 🧪
EMBO Gold Medal 2025 awarded to Tanmay Bharat and David Bikard – Press releases – EMBO
Every year, EMBO awards the Gold Medal to group leaders in the early stages of their careers for their remarkable contributions to the life sciences in
www.embo.org
June 5, 2025 at 4:24 PM
Incredibly grateful to my mentors, lab members, and generous collaborators who continue to inspire our work. Thankful also to microbial cell surfaces and tomography, which continue to deliver the excitement everyday!
Reposted by Schmidt Lab Innsbruck
We're on the cover of @science.org this week. Awesome work by @florentwaltz.bsky.social. #CryoET is reaching crazy resolutions inside cells, and this is just the beginning. Fantastic interpretation of the proton motive force by @verenaresch.bsky.social. Always a pleasure making #SciArt with you!🧪🧶🧬🌾
In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.
Learn more in this week's issue: scim.ag/3FA3Ygq
Learn more in this week's issue: scim.ag/3FA3Ygq
March 20, 2025 at 10:37 PM
We're on the cover of @science.org this week. Awesome work by @florentwaltz.bsky.social. #CryoET is reaching crazy resolutions inside cells, and this is just the beginning. Fantastic interpretation of the proton motive force by @verenaresch.bsky.social. Always a pleasure making #SciArt with you!🧪🧶🧬🌾
Amazing structure...
www.science.org/doi/10.1126/...
TOM complex and kinase... wait, something feels rather familiar here ;)
www.science.org/doi/10.1126/...
TOM complex and kinase... wait, something feels rather familiar here ;)
Structure of human PINK1 at a mitochondrial TOM-VDAC array
Mutations in the ubiquitin kinase PINK1 cause early onset Parkinson’s Disease, but how PINK1 is stabilized at depolarized mitochondrial translocase complexes has remained poorly understood. We determi...
www.science.org
March 14, 2025 at 1:44 PM
Amazing structure...
www.science.org/doi/10.1126/...
TOM complex and kinase... wait, something feels rather familiar here ;)
www.science.org/doi/10.1126/...
TOM complex and kinase... wait, something feels rather familiar here ;)
Reposted by Schmidt Lab Innsbruck
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
February 8, 2025 at 9:21 PM
It’s been a tough few weeks. My 10yo daughter was diagnosed with a very rare, aggressive cancer called interdigitating dendritic cell sarcoma (IDCS). I’m reaching out to identify clinicians/patients who have encountered pediatric IDCS or other (non-LCH) dendritic or histiocytic sarcomas cases.
Reposted by Schmidt Lab Innsbruck
🚨🚨 We are proud to launch MemBioMed, a new international Master program offering interdisciplinary training in biomembrane research at 3 sites: Université de Côte d'Azur 🇫🇷 Università di Genova 🇮🇹 & Osnabrück University 🇩🇪. We offer 15 scholarships & encourage talented students to apply by April 6th ♻️🙏
January 25, 2025 at 8:19 PM
🚨🚨 We are proud to launch MemBioMed, a new international Master program offering interdisciplinary training in biomembrane research at 3 sites: Université de Côte d'Azur 🇫🇷 Università di Genova 🇮🇹 & Osnabrück University 🇩🇪. We offer 15 scholarships & encourage talented students to apply by April 6th ♻️🙏