A/Prof Sam Stehbens PhD (She/Her)
@samstehbens.bsky.social
Everything microtubules, movement, and microscopy. ARC Future Fellow, lab head University of Queensland #CatsOfAcademia advoCATe. UCSF Wittmann lab alumni.
Pinned
What we do: work out how cells move by watching them. (Movies by Robert Ju; you can check out his work (art?) here: www.nature.com/articles/s41...
> I'll repost the paper tutorial later for those who are interested). #microscopy #microtubules #cytoskeleton #cellmigration #confinement
> I'll repost the paper tutorial later for those who are interested). #microscopy #microtubules #cytoskeleton #cellmigration #confinement
Reposted by A/Prof Sam Stehbens PhD (She/Her)
Hey ARC DPers with career interruptions- take a "print screen" of what you enter in your career interruptions boxes- seems like the ARC will never make this info roll over so do your future self a favour if it's a complicated set of dates 😭 (yes I have it saved elsewhere) @arc-tracker.bsky.social
November 25, 2025 at 5:30 AM
Hey ARC DPers with career interruptions- take a "print screen" of what you enter in your career interruptions boxes- seems like the ARC will never make this info roll over so do your future self a favour if it's a complicated set of dates 😭 (yes I have it saved elsewhere) @arc-tracker.bsky.social
Reposted by A/Prof Sam Stehbens PhD (She/Her)
ARC says they’ll announce DECRA and LIEF outcomes tomorrow (Tuesday 25th Nov).
In recent times these announcements have been around 11am Canberra time. With 2 schemes on the same day, I assume they’ll announce one of them later in the day (probably DECRA first).
In recent times these announcements have been around 11am Canberra time. With 2 schemes on the same day, I assume they’ll announce one of them later in the day (probably DECRA first).
November 23, 2025 at 11:40 PM
ARC says they’ll announce DECRA and LIEF outcomes tomorrow (Tuesday 25th Nov).
In recent times these announcements have been around 11am Canberra time. With 2 schemes on the same day, I assume they’ll announce one of them later in the day (probably DECRA first).
In recent times these announcements have been around 11am Canberra time. With 2 schemes on the same day, I assume they’ll announce one of them later in the day (probably DECRA first).
I don’t know how they did it but someone found actual footage of @davidbryantlab.bsky.social and I on the dance for at the 2005 Cell contact and adhesion GRC.
November 22, 2025 at 8:23 AM
I don’t know how they did it but someone found actual footage of @davidbryantlab.bsky.social and I on the dance for at the 2005 Cell contact and adhesion GRC.
Reposted by A/Prof Sam Stehbens PhD (She/Her)
"The ins and outs of microtubule regulation in centrioles and cilia"
CSHL Keynote, Dr. Anna Akhmanova, Utrecht University
CSHL Leading Strand
youtu.be/X0nm0xGjwOQ?...
CSHL Keynote, Dr. Anna Akhmanova, Utrecht University
CSHL Leading Strand
youtu.be/X0nm0xGjwOQ?...
CSHL Keynote, Dr. Anna Akhmanova, Utrecht University
YouTube video by CSHL Leading Strand
youtu.be
November 20, 2025 at 1:21 AM
"The ins and outs of microtubule regulation in centrioles and cilia"
CSHL Keynote, Dr. Anna Akhmanova, Utrecht University
CSHL Leading Strand
youtu.be/X0nm0xGjwOQ?...
CSHL Keynote, Dr. Anna Akhmanova, Utrecht University
CSHL Leading Strand
youtu.be/X0nm0xGjwOQ?...
Reposted by A/Prof Sam Stehbens PhD (She/Her)
We got a large Helmholtz Bioengineering grant with Oliver Daumke, Artur Yakimovich, Alina Bazarova, and Dietrich Ruess to use protein design to target cancer.
Five open postdoctoral positions in Generative AI & Protein Engineering. Share & apply!
jobrxiv.org/job/max-delb...
Five open postdoctoral positions in Generative AI & Protein Engineering. Share & apply!
jobrxiv.org/job/max-delb...
Postdoctoral Positions in Protein Engineering
Post a job in 3min, or find thousands of job offers like this one at jobRxiv!
jobrxiv.org
November 21, 2025 at 7:08 AM
We got a large Helmholtz Bioengineering grant with Oliver Daumke, Artur Yakimovich, Alina Bazarova, and Dietrich Ruess to use protein design to target cancer.
Five open postdoctoral positions in Generative AI & Protein Engineering. Share & apply!
jobrxiv.org/job/max-delb...
Five open postdoctoral positions in Generative AI & Protein Engineering. Share & apply!
jobrxiv.org/job/max-delb...
Reposted by A/Prof Sam Stehbens PhD (She/Her)
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.
It ships many new features, detailed below, but that are articulated around the following:
It ships many new features, detailed below, but that are articulated around the following:
November 20, 2025 at 11:42 AM
We just released a new major version of TrackMate (v8), the cell and organelle tracking plugin of Fiji.
It ships many new features, detailed below, but that are articulated around the following:
It ships many new features, detailed below, but that are articulated around the following:
Reposted by A/Prof Sam Stehbens PhD (She/Her)
1/ Clare M. Waterman is a cell biologist who has worked on understanding the role of the cytoskeleton in cell migration.
November 17, 2025 at 1:00 PM
1/ Clare M. Waterman is a cell biologist who has worked on understanding the role of the cytoskeleton in cell migration.
Reposted by A/Prof Sam Stehbens PhD (She/Her)
There's not long left for you to submit your abstract for Signalling Circuits in Cancer!
If your research falls into any of these categories, don't miss your opportunity to be included in this new conference topic.
eacr.org/conference/s...
If your research falls into any of these categories, don't miss your opportunity to be included in this new conference topic.
eacr.org/conference/s...
November 17, 2025 at 9:01 AM
There's not long left for you to submit your abstract for Signalling Circuits in Cancer!
If your research falls into any of these categories, don't miss your opportunity to be included in this new conference topic.
eacr.org/conference/s...
If your research falls into any of these categories, don't miss your opportunity to be included in this new conference topic.
eacr.org/conference/s...
November 16, 2025 at 4:27 AM
Hot tip- when you remove references from your pre print for publication in journals that limit references- make sure the ones you cite *actually* support what you’re referencing…..
November 14, 2025 at 11:43 PM
Hot tip- when you remove references from your pre print for publication in journals that limit references- make sure the ones you cite *actually* support what you’re referencing…..
Reposted by A/Prof Sam Stehbens PhD (She/Her)
Dang, hard disagree. The best papers to write and read are works of art, not merely a list of data and statements.
Don’t let LLMs take this away too, for gods sake.
Don’t let LLMs take this away too, for gods sake.
I honestly think we would all be a lot more productive if papers were bullet points with plots.
November 14, 2025 at 10:22 PM
Dang, hard disagree. The best papers to write and read are works of art, not merely a list of data and statements.
Don’t let LLMs take this away too, for gods sake.
Don’t let LLMs take this away too, for gods sake.
Reposted by A/Prof Sam Stehbens PhD (She/Her)
I have some BIG NEWS to share today!
Today I begin my next adventure as
Chief Editor of Nature Biomedical Engineering!!
(a thread) @natmethods.nature.com @natbiomedeng.nature.com @natureportfolio.nature.com
Today I begin my next adventure as
Chief Editor of Nature Biomedical Engineering!!
(a thread) @natmethods.nature.com @natbiomedeng.nature.com @natureportfolio.nature.com
a bunch of balloons are flying in the sky .
ALT: a bunch of balloons are flying in the sky .
media.tenor.com
August 1, 2025 at 2:27 PM
I have some BIG NEWS to share today!
Today I begin my next adventure as
Chief Editor of Nature Biomedical Engineering!!
(a thread) @natmethods.nature.com @natbiomedeng.nature.com @natureportfolio.nature.com
Today I begin my next adventure as
Chief Editor of Nature Biomedical Engineering!!
(a thread) @natmethods.nature.com @natbiomedeng.nature.com @natureportfolio.nature.com
Reposted by A/Prof Sam Stehbens PhD (She/Her)
How I recovered from a collaboration gone wrong www.science.org/content/arti...
How I recovered from a collaboration gone wrong
After learning “how quickly ‘we’ can turn wicked,” this researcher reshaped his approach
www.science.org
November 12, 2025 at 7:00 PM
How I recovered from a collaboration gone wrong www.science.org/content/arti...
Reposted by A/Prof Sam Stehbens PhD (She/Her)
Are you a postdoc or Asst. Prof on the job market? Check out our listing and consider applying! The search is very broad and it’s in a great department, location, university! Even with the crazy schedule that comes with being a PI- I love my job @ucdavis.bsky.social @ucdavisvetmed.bsky.social!
Our department @ucdavisvetmed.bsky.social @ucdavis.bsky.social is hiring! We welcome research that diversifies or complements existing strengths in gastrointestinal, neuroimmune, musculoskeletal, cardiorespiratory
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
systems and/or developmental biology. @socdevbio.bsky.social @ascbiology.bsky.social
November 12, 2025 at 6:54 PM
Are you a postdoc or Asst. Prof on the job market? Check out our listing and consider applying! The search is very broad and it’s in a great department, location, university! Even with the crazy schedule that comes with being a PI- I love my job @ucdavis.bsky.social @ucdavisvetmed.bsky.social!
Reposted by A/Prof Sam Stehbens PhD (She/Her)
Nature research paper: SIGLEC12 mediates plasma membrane rupture during necroptotic cell death
go.nature.com/4hSSG5Q
go.nature.com/4hSSG5Q
SIGLEC12 mediates plasma membrane rupture during necroptotic cell death - Nature
CRISPR–Cas9-based genome-wide screening shows that SIGLEC12 mediates plasma membrane rupture in cells undergoing necroptosis, possibly through a human-specific mechanism, indicating its potential as a therapeutic target.
go.nature.com
November 12, 2025 at 7:15 PM
Nature research paper: SIGLEC12 mediates plasma membrane rupture during necroptotic cell death
go.nature.com/4hSSG5Q
go.nature.com/4hSSG5Q
Reposted by A/Prof Sam Stehbens PhD (She/Her)
Kinesin-1-driven microtubule sliding helps pancreatic β cells reorganise their cytoskeleton in response to glucose.
buff.ly/r3BlzFj
buff.ly/r3BlzFj
November 12, 2025 at 11:01 AM
Kinesin-1-driven microtubule sliding helps pancreatic β cells reorganise their cytoskeleton in response to glucose.
buff.ly/r3BlzFj
buff.ly/r3BlzFj
Reposted by A/Prof Sam Stehbens PhD (She/Her)
Peiyao Fan, Yang Chen et al. @pku1898.bsky.social show that tubular ER extends into retraction fibers and #migrasomes through #microtubule-dependent ER extension and ER-plasma membrane contact sites in migrating cells. rupress.org/jcb/article/...
#ER_literature #Migration #Organelles
#ER_literature #Migration #Organelles
November 6, 2025 at 5:00 PM
Peiyao Fan, Yang Chen et al. @pku1898.bsky.social show that tubular ER extends into retraction fibers and #migrasomes through #microtubule-dependent ER extension and ER-plasma membrane contact sites in migrating cells. rupress.org/jcb/article/...
#ER_literature #Migration #Organelles
#ER_literature #Migration #Organelles
Reposted by A/Prof Sam Stehbens PhD (She/Her)
I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange).
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
November 7, 2025 at 9:25 PM
I love to see the endoplasmic reticulum (ER, cyan) hitchhiking over microtubules (MTs, orange).
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
Also the membrane dynamics are lovely.
It's been a while, but here we are for a late #fluorescencefriday with some #microscopy
#scicomm #scisky @cellcommlab.bsky.social focalplane.bsky.social 🧪🔬
Reposted by A/Prof Sam Stehbens PhD (She/Her)
#Tubulin regulates stability and localization of STMN2 by binding preferentially to its soluble form, say Xiang Deng, Timothy Mitchison and colleagues @harvardmed.bsky.social: rupress.org/jcb/article/...
#ProteinHomeostasis #Neuroscience #Biochemistry #Cytoskeleton #Neurodegeneration #ALS
#ProteinHomeostasis #Neuroscience #Biochemistry #Cytoskeleton #Neurodegeneration #ALS
November 7, 2025 at 7:30 PM
#Tubulin regulates stability and localization of STMN2 by binding preferentially to its soluble form, say Xiang Deng, Timothy Mitchison and colleagues @harvardmed.bsky.social: rupress.org/jcb/article/...
#ProteinHomeostasis #Neuroscience #Biochemistry #Cytoskeleton #Neurodegeneration #ALS
#ProteinHomeostasis #Neuroscience #Biochemistry #Cytoskeleton #Neurodegeneration #ALS
Reposted by A/Prof Sam Stehbens PhD (She/Her)
ICYMI: New Online! Microtubules provide a mechanical link for YAP/TAZ signalling
Microtubules provide a mechanical link for YAP/TAZ signalling
Nature Reviews Molecular Cell Biology, Published online: 05 November 2025; doi:10.1038/s41580-025-00929-xA study finds that mechanical activation leads to microtubule rearrangement, facilitating the proteasomal degradation of an inhibitor of YAP/TAZ, thus promoting YAP/TAZ nuclear translocation.
bit.ly
November 8, 2025 at 3:54 PM
ICYMI: New Online! Microtubules provide a mechanical link for YAP/TAZ signalling
Trying to catch up on some missed work on the weekend. Phoebe is not helping. #CatsOfAcademia #AustralianMist
November 8, 2025 at 3:19 AM
Trying to catch up on some missed work on the weekend. Phoebe is not helping. #CatsOfAcademia #AustralianMist
Reposted by A/Prof Sam Stehbens PhD (She/Her)
Research | Amiad Pavlov, Heffler et al. demonstrate that stress transmitted to the cardiomyocyte nucleus by the microtubule cage drives LMNA-associated cardiomyopathy and may represent a promising therapeutic target.
doi.org/10.1038/s441...
rdcu.be/eOeTA
doi.org/10.1038/s441...
rdcu.be/eOeTA
Microtubule forces drive nuclear damage in LMNA cardiomyopathy - Nature Cardiovascular Research
Amiad Pavlov, Heffler, et al. demonstrate that stress transmitted to the cardiomyocyte nucleus by the microtubule cage drives LMNA-associated cardiomyopathy and may represent a promising therapeutic t...
doi.org
November 4, 2025 at 2:56 PM
Research | Amiad Pavlov, Heffler et al. demonstrate that stress transmitted to the cardiomyocyte nucleus by the microtubule cage drives LMNA-associated cardiomyopathy and may represent a promising therapeutic target.
doi.org/10.1038/s441...
rdcu.be/eOeTA
doi.org/10.1038/s441...
rdcu.be/eOeTA
@charlesdcox.bsky.social defining what makes a ‘Piezo fanatic’ at #MechBio2025 #AusMB 👉 @ardemp.bskyverified.social ‘s commitment #STEM (it is a bit kettle-Pot really 😂 ).
November 5, 2025 at 4:40 AM
@charlesdcox.bsky.social defining what makes a ‘Piezo fanatic’ at #MechBio2025 #AusMB 👉 @ardemp.bskyverified.social ‘s commitment #STEM (it is a bit kettle-Pot really 😂 ).
Reposted by A/Prof Sam Stehbens PhD (She/Her)
☕Vanni et al. show a role for #microtubules in YAP/TAZ mechanosignalling. Mechanoresponsive microtubule reorganization into centrosomal arrays allows for AMOT delivery to pericentrosomal proteasomes and degradation, leading to YAP/TAZ activation. #mechanobiology #cytoskeleton
bit.ly/4oS2Ju3
bit.ly/4oS2Ju3
Microtubule architecture connects AMOT stability to YAP/TAZ mechanotransduction and Hippo signalling - Nature Cell Biology
Vanni et al. show a role for microtubules in YAP/TAZ mechanosignalling. Mechanoresponsive microtubule reorganization into centrosomal arrays allows for AMOT delivery to pericentrosomal proteasomes and...
bit.ly
November 4, 2025 at 6:35 PM
☕Vanni et al. show a role for #microtubules in YAP/TAZ mechanosignalling. Mechanoresponsive microtubule reorganization into centrosomal arrays allows for AMOT delivery to pericentrosomal proteasomes and degradation, leading to YAP/TAZ activation. #mechanobiology #cytoskeleton
bit.ly/4oS2Ju3
bit.ly/4oS2Ju3
Looking forward to all things Australian #Mechanobiology tomorrow! #OzMechBio #ausmb. ausmb.org/meetings_202...
Mechanobiology2025
Join us for MechBio2025, the annual meeting of the Australian Society for Mechanobiology. November 5-7, 2025 at the University of Queensland, Brisbane. Featuring international keynote speakers and sho...
ausmb.org
November 4, 2025 at 11:04 AM
Looking forward to all things Australian #Mechanobiology tomorrow! #OzMechBio #ausmb. ausmb.org/meetings_202...