Susan Logue
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loguesusan.bsky.social
Susan Logue
@loguesusan.bsky.social
530 followers 300 following 26 posts
ER stress, Unfolded Protein Response, cancer, inflammation. 🇮🇪 🇨🇦 University of Manitoba Views are my own.
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Reposted by Susan Logue
afshinsamali.bsky.social
🎓 Want to do a PhD in cancer biology?
ARC, @universityofgalway.bsky.social offering 2 funded #PhD positions (€25k + fees) starting in 2026.
Focus: #IRE1 signaling in breast cancer.
Apply by 12 Dec 2025
📧 [email protected]
#CancerResearch #TNBC #MolecularBiology #PhDPositions
November 20, 2025 at 2:16 PM
loguesusan.bsky.social
Interesting perspective on GRP78 by Amy Lee #ER_Literature
Stress-induced translocation of the endoplasmic reticulum chaperone GRP78/BiP and its impact on human disease and therapy | PNAS www.pnas.org/doi/10.1073/...
PNAS
Proceedings of the National Academy of Sciences (PNAS), a peer reviewed journal of the National Academy of Sciences (NAS) - an authoritative source of high-impact, original research that broadly spans...
www.pnas.org
August 13, 2025 at 4:33 PM
loguesusan.bsky.social
Dissecting Branch-Specific Unfolded Protein Response Activation in Drug-Tolerant BRAF-Mutant Melanoma using Data-Independent Acquisition Mass Spectrometry - Molecular & Cellular Proteomics www.mcponline.org/article/S153...
Dissecting Branch-Specific Unfolded Protein Response Activation in Drug-Tolerant BRAF-Mutant Melanoma using Data-Independent Acquisition Mass Spectrometry
Cells rely on the Unfolded Protein Response (UPR) to maintain ER protein homeostasis (proteostasis) when faced with elevated levels of misfolded and aggregated proteins. The UPR is comprised of three ...
www.mcponline.org
July 25, 2025 at 5:15 PM
loguesusan.bsky.social
Optogenetic Clustering of Human IRE1 Reveals Differential Regulation of Transcription and mRNA Splice Isoform Abundance by the UPR
www.biorxiv.org/content/10.1...
Optogenetic Clustering of Human IRE1 Reveals Differential Regulation of Transcription and mRNA Splice Isoform Abundance by the UPR
Inositol-requiring enzyme 1 (IRE1) is one of three known sensor proteins that respond to homeostatic perturbations in the metazoan endoplasmic reticulum. The three sensors collectively initiate an int...
www.biorxiv.org
July 22, 2025 at 6:34 PM
loguesusan.bsky.social
Check out this weeks selection of Unfolded Protein Response papers!
biomed.news/bims-unfpre/...
Thanks @biomednews.bsky.social
bims-unfpre 2025-04-27 papers
biomed.news
April 27, 2025 at 3:33 PM
Reposted by Susan Logue
um-radyfhs.bsky.social
After testing 8,500 drugs, the research team discovered that poziotinib – a drug that already exists and is approved for other cancers – reduced breast cancer brain metastasis tumours in mice after two weeks of treatment. #Medsky #cancerresearch #radyfaculty
UM-led study offers hope that existing drug can target metastatic brain tumours
A University of Manitoba-led study successfully eliminated breast-cancer derived brain tumours in mice, using a drug to penetrate the brain and eliminate metastatic brain tumours. After testing 8,500
news.umanitoba.ca
April 15, 2025 at 7:41 PM
loguesusan.bsky.social
Lots of great Unfolded Protein Response papers this week....
biomed.news/bims-unfpre/... thanks @biomednews.bsky.social
bims-unfpre 2025-04-13 papers
biomed.news
April 13, 2025 at 4:27 PM
loguesusan.bsky.social
Happy St Patrick’s Day, Lá Fhéile Pádraig sona daoibh
March 17, 2025 at 12:30 PM
loguesusan.bsky.social
Celebrating Irish change-makers across the globe
youtu.be/MeIcN6KJSlU?...
St Patrick’s Day 2025 – Celebrating Irish change-makers across the globe #stpatricksday
YouTube video by Department of Foreign Affairs and Trade, Ireland
youtu.be
March 14, 2025 at 12:42 PM
Reposted by Susan Logue
joechambers.bsky.social
Delighted to share our latest paper on alpha-1-antitrypsin deficiency, in @naturegenet.bsky.social.

A fun collaboration between groups of @matthoare20.bsky.social, @profmarciniak.bsky.social, and Peter Campbell.

@thecimr.bsky.social ky.social, @sangerinstitute.bsky.social, Early Cancer Institute
Selection for somatic escape variants in SERPINA1 in the liver of patients with alpha-1 antitrypsin deficiency - Nature Genetics
The expansion of clones with distinct SERPINA1 somatic mutants in the livers of alpha-1 antitrypsin deficiency (A1AT) patients is consistent with convergent evolution. These variants interfere with th...
www.nature.com
March 10, 2025 at 10:38 AM
Reposted by Susan Logue
cvasilescu.bsky.social
Here it is, the #mitochondrialdisease selection of papers from last week! 📚
biomed.news/bims-mitdis/...

@biomednews.bsky.social @gavinmcstay.bsky.social @mitoworld.bsky.social @mitowomen.bsky.social @mitoscientist.bsky.social

Many interesting findings, a few highlights in the comments below! 👇
Woman scientist reading books.
March 9, 2025 at 3:21 PM
loguesusan.bsky.social
Fantastic article from Linda Hendershot—an incredible scientist and one of the most supportive and inspiring researchers I've had the pleasure of meeting.
www.sciencedirect.com/science/arti...
A BiP-centric view of endoplasmic reticulum functions and of my career
After completing my post-doctoral training at the University of Alabama, Birmingham and a brief period on the faculty there, I joined the Department o…
www.sciencedirect.com
March 9, 2025 at 6:43 PM
Reposted by Susan Logue
drdonnamartin.bsky.social
Hugh Kearns @umanitoba.bsky.social April 7 Bannatyne Campus, April 10 at FG
7 secrets to research success QR code for details
Photo of Hugh Kearns, announcing Sam Weiner Distinguished Visitor Awardee QR code to register
March 8, 2025 at 1:37 AM
loguesusan.bsky.social
This weeks selection of Unfolded Protein Response papers
biomed.news/bims-unfpre/... @biomednews.bsky.social
March 5, 2025 at 3:40 PM
loguesusan.bsky.social
Now to sprinkle the last ingredient of a little magic dust over this grant…….third time lucky?🤞🤞
a man wearing sunglasses and a white tank top says " a little bit of magic dust "
ALT: a man wearing sunglasses and a white tank top says " a little bit of magic dust "
media.tenor.com
February 28, 2025 at 6:49 PM
loguesusan.bsky.social
Past few weeks of Unfolded Protein Response papers! #ERStress @biomednews.bsky.social
biomed.news/bims-unfpre/...
biomed.news/bims-unfpre/...
biomed.news/bims-unfpre/...
February 23, 2025 at 2:25 PM
loguesusan.bsky.social
After a long delay time to catch up on Unfoled Protein Response related papers! @biomednews.bsky.social
biomed.news/bims-unfpre/...
biomed.news/bims-unfpre/...
biomed.news/bims-unfpre/...
biomed.news/bims-unfpre/...
biomed.news/bims-unfpre/...
biomed.news/bims-unfpre/...
February 21, 2025 at 4:46 PM
Reposted by Susan Logue
meaghanjones.bsky.social
Come be my colleague! We are hiring very broadly in cancer biology. Great colleagues and department, lots of support, sure the winter is cold but our hearts are warm!
umbmg.bsky.social Biochemistry & Medical Genetics @umbmg.bsky.social · Feb 11
🚨We're hiring! 🚨

BMG is seeking an Assistant/Associate Professor with expertise in Cancer Biology—focusing on genetics and/or biochemistry.

📅 Application review begins March 31, 2025.

🔗More info: viprecprod.ad.umanitoba.ca/DEFAULT.ASPX...
viprecprod.ad.umanitoba.ca
February 11, 2025 at 4:46 PM
Reposted by Susan Logue
umbmg.bsky.social
🚨We're hiring! 🚨

BMG is seeking an Assistant/Associate Professor with expertise in Cancer Biology—focusing on genetics and/or biochemistry.

📅 Application review begins March 31, 2025.

🔗More info: viprecprod.ad.umanitoba.ca/DEFAULT.ASPX...
viprecprod.ad.umanitoba.ca
February 11, 2025 at 4:29 PM
Reposted by Susan Logue
kirkmcmanuslab.bsky.social
Great opportunity for an Assistant/Associate Professor position in #CancerBiology in the Department of Biochemistry & Medical Genetics at the University of Manitoba. Supportive environment and Winnipeg is a great and affordable city!
bit.ly/4gKnmnS
February 11, 2025 at 9:28 PM
loguesusan.bsky.social
ER stress peeps I have a question - is there a paper that demonstrates p-PERK ab are not always a reliable method to detect PERK activation? I have a vague recollection of a paper but can’t seem to find it….
January 16, 2025 at 3:53 PM
Reposted by Susan Logue
ericchevet.bsky.social
The University of Rennes is recruiting an assistant professor (Maître de Conférence) in bioinformatics with a research activity in our unit (oss-clcc.univ-rennes.fr) - if you seek for some information regarding the research them please DM me
January 6, 2025 at 8:16 PM
Reposted by Susan Logue
cahirokane.bsky.social
Experience Postgrad Life Sciences in @cambridgebiosci.bsky.social
Paid 8-week research internships, for undergraduates in their penultimate year at a UK/Irish university. Aimed at talented students who might not otherwise feel they can easily access summer research opportunities.
Experience Postgrad Life Sciences | Enhancing diversity among life scientists of the future
www.exppg.lifesci.cam.ac.uk
January 5, 2025 at 12:00 PM
Reposted by Susan Logue
gthibault.bsky.social
🌟 Registration is now OPEN for the #FASEB Endoplasmic Reticulum Conference 2025 #ERSRC! 🎉 Join us June 8-12, 2025, in Melbourne 🏖️, FL, for cutting-edge science and networking.

Check out the program and register here 👇

events.faseb.org/event/endoplasmic-reticulum-function-disease
Endoplasmic Reticulum
events.faseb.org
December 11, 2024 at 12:23 AM
Reposted by Susan Logue
profmarciniak.bsky.social
Arise, UPR & ISR scientists !

I will have missed many, so please tag below
go.bsky.app/8VzRKLW
November 24, 2024 at 9:23 AM