Marjon de Vos
@lizscurious.bsky.social
Cares about tiny things in a larger context
Asst prof @uniGroningen
Microbiology, ecology, evolution
#AMR, #UTI
microbecoevo.com
Asst prof @uniGroningen
Microbiology, ecology, evolution
#AMR, #UTI
microbecoevo.com
Reposted by Marjon de Vos
We are organising an AMR meeting next spring in Helsinki. Meeting includes evolution of AMR and environmental AMR sessions. Please submit your abstract now! Deadline Dec 1st.
November 25, 2025 at 12:48 PM
We are organising an AMR meeting next spring in Helsinki. Meeting includes evolution of AMR and environmental AMR sessions. Please submit your abstract now! Deadline Dec 1st.
Reposted by Marjon de Vos
Really pleased to share the first paper to come out of the lab.
We found that hospital patients were frequently colonised with P. aeruginosa and that the same clone was shared between the gut and the lung.
The phylogenies indicate that the clones moved from lung->gut
www.nature.com/articles/s41...
We found that hospital patients were frequently colonised with P. aeruginosa and that the same clone was shared between the gut and the lung.
The phylogenies indicate that the clones moved from lung->gut
www.nature.com/articles/s41...
High frequency body site translocation of nosocomial Pseudomonas aeruginosa - Nature Communications
Here, the authors report within-host diversity and body site translocation dynamics in hospital samples of Pseudomonas aeruginosa and reveal that body site sharing was likely due to within-patient tra...
www.nature.com
November 25, 2025 at 10:40 AM
Really pleased to share the first paper to come out of the lab.
We found that hospital patients were frequently colonised with P. aeruginosa and that the same clone was shared between the gut and the lung.
The phylogenies indicate that the clones moved from lung->gut
www.nature.com/articles/s41...
We found that hospital patients were frequently colonised with P. aeruginosa and that the same clone was shared between the gut and the lung.
The phylogenies indicate that the clones moved from lung->gut
www.nature.com/articles/s41...
Reposted by Marjon de Vos
Really happy to see the final version of this published in @isme-microbes.bsky.social. We show that production of and competition for biotin shapes S. aureus fitness in the context of nasal commensals doi.org/10.1093/isme...
Work lead by the amazing Kevser Bilici!
Work lead by the amazing Kevser Bilici!
Competitive fitness of Staphylococcus aureus against nasal commensals depends on biotin biosynthesis and acquisition
Abstract. The human nasal microbiome can serve as a reservoir for pathogens. In particular, the opportunistic pathogen Staphylococcus aureus can be a membe
doi.org
November 24, 2025 at 5:54 PM
Really happy to see the final version of this published in @isme-microbes.bsky.social. We show that production of and competition for biotin shapes S. aureus fitness in the context of nasal commensals doi.org/10.1093/isme...
Work lead by the amazing Kevser Bilici!
Work lead by the amazing Kevser Bilici!
Reposted by Marjon de Vos
We've had to wait a long time to get to this point! With this new pair of Cochrane systematic reviews, the weight of the evidence has tipped very heavily in favor of HPV vaccination.
My new post @plos.org absolutelymaybe.plos.org/2025/11/24/t...
#Vaccines
My new post @plos.org absolutelymaybe.plos.org/2025/11/24/t...
#Vaccines
This Evidence Fundamentally Shifts the Debate About the HPV Vaccine - Absolutely Maybe
We’ve had to wait a long time to get to this point. If cervical cancer develops after HPV infection, it will take…
absolutelymaybe.plos.org
November 24, 2025 at 10:24 AM
We've had to wait a long time to get to this point! With this new pair of Cochrane systematic reviews, the weight of the evidence has tipped very heavily in favor of HPV vaccination.
My new post @plos.org absolutelymaybe.plos.org/2025/11/24/t...
#Vaccines
My new post @plos.org absolutelymaybe.plos.org/2025/11/24/t...
#Vaccines
Reposted by Marjon de Vos
It's time to remove laptops from classrooms.
24 experiments: Students learn more and get better grades after taking notes by hand than typing. It's not just because they're less distracted—writing enables deeper processing and more images.
The pen is mightier than the keyboard.
24 experiments: Students learn more and get better grades after taking notes by hand than typing. It's not just because they're less distracted—writing enables deeper processing and more images.
The pen is mightier than the keyboard.
November 20, 2025 at 3:09 PM
It's time to remove laptops from classrooms.
24 experiments: Students learn more and get better grades after taking notes by hand than typing. It's not just because they're less distracted—writing enables deeper processing and more images.
The pen is mightier than the keyboard.
24 experiments: Students learn more and get better grades after taking notes by hand than typing. It's not just because they're less distracted—writing enables deeper processing and more images.
The pen is mightier than the keyboard.
Reposted by Marjon de Vos
Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Intracellular competition shapes plasmid population dynamics
From populations of multicellular organisms to selfish genetic elements, conflicts between levels of biological organization are central to evolution. Plasmids are extrachromosomal, self-replicating g...
www.science.org
November 20, 2025 at 9:42 PM
Hot off the press! Our latest paper led by @fernpizza.bsky.social, understanding how plasmids evolve inside cells. These small, self-replicating DNA circles live inside bacteria and carry antibiotic resistance genes, but also compete with one another to replicate. 1/
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...
Reposted by Marjon de Vos
I really hate it when scientists keep saying that “we need to rebuild trust in science,” because it implies that scientists are to blame for the mistrust rather than the millions of dollars of dark money that have funded political attacks on science in order to advance a far right agenda.
November 19, 2025 at 9:48 PM
I really hate it when scientists keep saying that “we need to rebuild trust in science,” because it implies that scientists are to blame for the mistrust rather than the millions of dollars of dark money that have funded political attacks on science in order to advance a far right agenda.
Reposted by Marjon de Vos
Why does daptomycin resistance appear so fast in Enterococcus? We finally have a clue.
DAP resistance in enterococci pops up quickly. What’s been missing is why resistance-associated membrane changes look the way they do, and why the classic path of mutations is so predictable.
DAP resistance in enterococci pops up quickly. What’s been missing is why resistance-associated membrane changes look the way they do, and why the classic path of mutations is so predictable.
A two-component system signaling hub controls enterococcal membrane remodeling in response to daptomycin https://www.biorxiv.org/content/10.1101/2025.11.16.688641v1
November 17, 2025 at 8:27 PM
Why does daptomycin resistance appear so fast in Enterococcus? We finally have a clue.
DAP resistance in enterococci pops up quickly. What’s been missing is why resistance-associated membrane changes look the way they do, and why the classic path of mutations is so predictable.
DAP resistance in enterococci pops up quickly. What’s been missing is why resistance-associated membrane changes look the way they do, and why the classic path of mutations is so predictable.
Reposted by Marjon de Vos
Twee jaar geleden bracht de Algemene Rekenkamer het rapport “Focus op vogelgriep” uit over de kosten van de vogelgriepepidemie tussen 2021 en 2023. Nu dat vogelgriep weer opspeelt is het goed om een aantal conclusies uit het rapport ter herinnering te nemen. www.rekenkamer.nl/documenten/2...
November 19, 2025 at 5:31 AM
Twee jaar geleden bracht de Algemene Rekenkamer het rapport “Focus op vogelgriep” uit over de kosten van de vogelgriepepidemie tussen 2021 en 2023. Nu dat vogelgriep weer opspeelt is het goed om een aantal conclusies uit het rapport ter herinnering te nemen. www.rekenkamer.nl/documenten/2...
Reposted by Marjon de Vos
gggenomes: A Grammar of Graphics for Comparative Genomics thackl.github.io/gggenomes/ #Rstats
A Grammar of Graphics for Comparative Genomics
An extension of ggplot2 for creating complex genomic maps. It builds on the power of ggplot2 and tidyverse adding new ggplot2-style geoms & positions and dplyr-style verbs to manipulate the…
thackl.github.io
November 18, 2025 at 7:02 PM
gggenomes: A Grammar of Graphics for Comparative Genomics thackl.github.io/gggenomes/ #Rstats
Reposted by Marjon de Vos
🚨#PhD studentship opportunity! Plasmids provide bacteria with antimicrobial resistance, but do they have more fundamental effects on behaviour? 🧫🦠💫🧟♂️
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Liverpool on Fin...
PhD Project - MRC DiMeN Doctoral Training Partnership: Resistant zombies: how drug-resistance plasmids manipulate the behaviour of the opportunistic pathogen Pseudomonas aeruginosa at University of Li...
www.findaphd.com
November 18, 2025 at 9:38 AM
🚨#PhD studentship opportunity! Plasmids provide bacteria with antimicrobial resistance, but do they have more fundamental effects on behaviour? 🧫🦠💫🧟♂️
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Apply for a 4y funded MRC DiMeN position with me and Jamie Wheeler @livuni-ives.bsky.social www.findaphd.com/phds/project...
Reposted by Marjon de Vos
When colonizing a new habitat, organisms adapt to maximize their reproductive success via #LifeHistory #evolution. @ecoevodevolab.bsky.social @cbank.bsky.social show that life history evolution facilitates niche diversification across a range of theoretical models @plosbiology.org 🧪 plos.io/4p7YT0a
November 13, 2025 at 10:02 AM
When colonizing a new habitat, organisms adapt to maximize their reproductive success via #LifeHistory #evolution. @ecoevodevolab.bsky.social @cbank.bsky.social show that life history evolution facilitates niche diversification across a range of theoretical models @plosbiology.org 🧪 plos.io/4p7YT0a
Reposted by Marjon de Vos
Er komt een nieuw kabinet. Maar de onderwijsbezuinigingen van 606 miljoen op het hoger onderwijs staan nog. We blijven druk zetten op de politiek en komen we 9/12 weer in actie! Zorg dat je erbij bent✊
Stop de sloop van het hoger onderwijs‼️
📍De Dam, Amsterdam
📅Di 9/12
🕛12:00 uur
lnkd.in/eAh3bTwZ
Stop de sloop van het hoger onderwijs‼️
📍De Dam, Amsterdam
📅Di 9/12
🕛12:00 uur
lnkd.in/eAh3bTwZ
November 12, 2025 at 3:48 PM
Er komt een nieuw kabinet. Maar de onderwijsbezuinigingen van 606 miljoen op het hoger onderwijs staan nog. We blijven druk zetten op de politiek en komen we 9/12 weer in actie! Zorg dat je erbij bent✊
Stop de sloop van het hoger onderwijs‼️
📍De Dam, Amsterdam
📅Di 9/12
🕛12:00 uur
lnkd.in/eAh3bTwZ
Stop de sloop van het hoger onderwijs‼️
📍De Dam, Amsterdam
📅Di 9/12
🕛12:00 uur
lnkd.in/eAh3bTwZ
Reposted by Marjon de Vos
Professor Joana Falcao Salles, a professor of Microbial Community Ecology at the University of Groningen, has been named as the newest winner of the Basil Jarvis Food Security and Innovation Award. @rug.nl www.the-microbiologist.com/news/horizon...
Horizon Awards 2025: Professor Joana Falcao Salles named as winner of Basil Jarvis Award
Professor Joana Falcao Salles, a professor of Microbial Community Ecology at the University of Groningen, has been named as the newest winner of the Basil Jarvis Food Security and Innovation Award.
www.the-microbiologist.com
November 12, 2025 at 11:01 AM
Professor Joana Falcao Salles, a professor of Microbial Community Ecology at the University of Groningen, has been named as the newest winner of the Basil Jarvis Food Security and Innovation Award. @rug.nl www.the-microbiologist.com/news/horizon...
Reposted by Marjon de Vos
New paper alert! DNA replication and repair conflicts lead to cell death in gram positive bacteria, possible new targets for novel antimicrobials.
@microbiologysociety.org @winterhalterlab.bsky.social www.microbiologyresearch.org/content/jour...
@microbiologysociety.org @winterhalterlab.bsky.social www.microbiologyresearch.org/content/jour...
Conflicts between the DNA replication and repair machineries promote cell death in Gram-positive bacteria
Cellular proliferation relies on the successful coordination and completion of genome replication and segregation. To help achieve this, many bacteria utilize regulatory pathways that ensure DNA repli...
www.microbiologyresearch.org
November 11, 2025 at 4:59 PM
New paper alert! DNA replication and repair conflicts lead to cell death in gram positive bacteria, possible new targets for novel antimicrobials.
@microbiologysociety.org @winterhalterlab.bsky.social www.microbiologyresearch.org/content/jour...
@microbiologysociety.org @winterhalterlab.bsky.social www.microbiologyresearch.org/content/jour...
Reposted by Marjon de Vos
Super excited that the bulk of my PhD work is now preprinted! Here we used whole-community competition, or coalescence, experiments to quantify selection acting on genetically diverged strains within larger communities. (1/n)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
www.biorxiv.org
November 11, 2025 at 5:15 PM
Super excited that the bulk of my PhD work is now preprinted! Here we used whole-community competition, or coalescence, experiments to quantify selection acting on genetically diverged strains within larger communities. (1/n)
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Marjon de Vos
ooof this feels like most every university rn
November 12, 2025 at 3:28 AM
ooof this feels like most every university rn
Reposted by Marjon de Vos
Cool paper from @smitslab.bsky.social Structural insights into how PolC-inhibitors work and can open up the road to a new suite of antibiotics www.nature.com/articles/s41...
A unique inhibitor conformation selectively targets the DNA polymerase PolC of Gram-positive priority pathogens - Nature Communications
In this work, Urem et al. characterize the mode of action as well as mechanism of reduced susceptibility related to a class of antimicrobials that is in development for the treatment of infections wit...
www.nature.com
November 7, 2025 at 3:10 PM
Cool paper from @smitslab.bsky.social Structural insights into how PolC-inhibitors work and can open up the road to a new suite of antibiotics www.nature.com/articles/s41...
Reposted by Marjon de Vos
🚨 Excited to share our new paper is out! 🎉
We show how interactions within gut microbiomes allow certain antibiotic-resistant E. coli strains to persist even without antibiotics, helping explain how resistance is maintained in the human gut.
Now published in @natcomms.nature.com rdcu.be/eOf63
We show how interactions within gut microbiomes allow certain antibiotic-resistant E. coli strains to persist even without antibiotics, helping explain how resistance is maintained in the human gut.
Now published in @natcomms.nature.com rdcu.be/eOf63
Multi-layered ecological interactions determine growth of clinical antibiotic-resistant strains within human microbiomes
Nature Communications - The role of ecological factors in modulating the spread of antibiotic-resistance bacteria in the gut remains unclear. Here, the authors use anaerobic microcosms to study the...
rdcu.be
November 7, 2025 at 9:15 AM
🚨 Excited to share our new paper is out! 🎉
We show how interactions within gut microbiomes allow certain antibiotic-resistant E. coli strains to persist even without antibiotics, helping explain how resistance is maintained in the human gut.
Now published in @natcomms.nature.com rdcu.be/eOf63
We show how interactions within gut microbiomes allow certain antibiotic-resistant E. coli strains to persist even without antibiotics, helping explain how resistance is maintained in the human gut.
Now published in @natcomms.nature.com rdcu.be/eOf63
Hannah Dugdale on Evolutionary Medicine and Aging at the first ENLIGHT-REACT workshop 'Modern Perspectives on the Biology of Ageing'
@react-enlight.bsky.social
@rug.nl
@react-enlight.bsky.social
@rug.nl
November 7, 2025 at 8:15 AM
Hannah Dugdale on Evolutionary Medicine and Aging at the first ENLIGHT-REACT workshop 'Modern Perspectives on the Biology of Ageing'
@react-enlight.bsky.social
@rug.nl
@react-enlight.bsky.social
@rug.nl
Reposted by Marjon de Vos
New(ish!) paper on how within-host competition and antibiotic resistance shape the fitness of Streptococcus pneumoniae serotypes, out in August in Plos Biology. journals.plos.org/plosbiology/...
Quantifying the effects of antibiotic resistance and within-host competition on strain fitness in Streptococcus pneumoniae
Competition significantly influences bacterial population dynamics, particularly in how strains interact within and between hosts. This study shows that within-host competition in Streptococcus pneumo...
journals.plos.org
October 31, 2025 at 3:05 PM
New(ish!) paper on how within-host competition and antibiotic resistance shape the fitness of Streptococcus pneumoniae serotypes, out in August in Plos Biology. journals.plos.org/plosbiology/...
Reposted by Marjon de Vos
Ik gooi deze klassieker er maar weer even tegenaan:
November 5, 2025 at 6:29 PM
Ik gooi deze klassieker er maar weer even tegenaan:
Reposted by Marjon de Vos
Another fantastic study from @lisamaierlab.bsky.social showing how non-antibiotics impact gut ecosytem. Congratulations @ghammeranne.bsky.social et al.!
Seeing this published is even better than eating sweets! I am so happy and proud of whole @lisamaierlab.bsky.social, especially Lisa and @jdlcz.bsky.social who walked the funny/exciting/rocky road with me until the very end. Check it out!
#science #microbiome #health
www.nature.com/articles/s41...
#science #microbiome #health
www.nature.com/articles/s41...
Non-antibiotics disrupt colonization resistance against enteropathogens - Nature
Non-antibiotic drugs from a wide range of therapeutic classes can alter the ability of gut commensals to resist invasion by enteropathogens, a previously underappreciated side effect of such drugs.
www.nature.com
July 17, 2025 at 12:23 PM
Another fantastic study from @lisamaierlab.bsky.social showing how non-antibiotics impact gut ecosytem. Congratulations @ghammeranne.bsky.social et al.!
Reposted by Marjon de Vos
We're just 6 months away from @keystoneSymposia.bsky.social Beyond #Antibiotics : Emerging Strategies Combating #BacterialInfection, May 2026 in Breckenridge! 👉Scholarship and short talk abstract deadlines are Jan 7! 🧐 keysym.us/KSBeyondAntibiotics26 #KSBeyondAntibiotics26
Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection | Keystone Symposia
Join us at the Keystone Symposia on Beyond Antibiotics: Emerging Strategies for Combating Bacterial Infection, May 2026, in Breckenridge, with field leaders!
keysym.us
November 4, 2025 at 2:47 PM
We're just 6 months away from @keystoneSymposia.bsky.social Beyond #Antibiotics : Emerging Strategies Combating #BacterialInfection, May 2026 in Breckenridge! 👉Scholarship and short talk abstract deadlines are Jan 7! 🧐 keysym.us/KSBeyondAntibiotics26 #KSBeyondAntibiotics26