Daughter of immigrants advocated for people with disabilities to have full autonomy over their lives

423 likes, 73 comments - alicatsamurai on November 14, 2025: "ID: Yellow background with black text "This is Alice's friend Sandy Ho, posting. Per Alice's wishes, this message is being shared at the t...

A researcher who found "dangerous" toxic metals in illegal anabolic steroids is in talks the health department officials to continue his work despite Queensland's drug checking ban.

Fluorinated analogs of ketamine, such as 2-fluoro-deschloroketamine and its isomers, have recently emerged as dissociative anesthetics that act throug…

Spurred by a recent report on sexual harassment in academia, our columnist revisits a historical case and reflects on what has changed—and what hasn’t

New psychoactive substances are a group of synthetic or naturally occurring drugs that mimic the effects of controlled illicit drugs. With limited inf…

YouTube video by Drugreporter

Nitazenes, a class of new psychoactive substances, have emerged as a significant public health and safety concern due to their widespread abuse. While various detection methods, particularly mass spectrometry, have been developed for these substances, there is limited information regarding their fragmentation pathways and isomeric identification. This knowledge is crucial for drug analysis and forensic toxicology. Among the mass spectrometry techniques, collision-induced dissociation (CID) is commonly used for analyzing the fragmentation of analytes; however, its fragmentation pattern may not be sufficient for complete characterization or differentiation of isomers. Electron-activated dissociation (EAD), a fragmentation technique, provides complementary data to CID by generating distinct fragment ions that aid in the identification and characterization of small molecules. This study aims to characterize and identify 17 kinds of nitazenes using CID and EAD in combination with liquid chromatography time-of-flight mass spectrometry (LC-TOF-MS). The chromatographic and mass spectrometric behaviors of these compounds were examined, and the fragments were analyzed, with a particular focus on the differences between isomers under CID and EAD modes. Notably, EAD generated more detailed fragmentation profiles than CID, revealing unique fragmentation pathways and characteristic fragment ions. In addition, the doubly charged ions of nitazenes were identified in the EAD spectra. Based on the CID and EAD fragmentation pathways of nitazenes, a novel substance was identified in a seized sample. These findings underscore the value of CID and EAD in enhancing forensic toxicology workflows by providing complementary fragmentation data that improve the identification and characterization of novel and unknown compounds.

Stop Forced Redundancies at QUT's Faculty of Science

Comprehensive toxicology testing of emergency department (ED) presentations has become a prominent data source on novel psychoactive substances (NPS) …

C&EN’s 2025 Trailblazers issue, curated by guest editor Mona Minkara, looks at how chemists can solve problems in new ways

Exclusive: Scientists from UNSW school of chemistry analyse sample of treatment, bought online and purported to mimic effects of Ozempic, and find nothing more than saline solution

drug checking, harm reduction, overdose prevention, NarxCare, fentanyl analogs, HALT Fentanyl Act, nitazenes, public health surveillance, Narcan, Overdose Chain of Survival, commercial determinants of...

AbstractBackground. Hexahydrocannabinol (HHC) and its analogs are recent additions to semi-synthetic cannabinoids in the recreational drug market. Here, th

A painterly, macro view of a cauliflower soft coral by Ross Gudgeon has taken out top prize

Scientists with disabilities ascended to the forefronts of their fields long before labs were accessible and civil rights were codified