Jonathan Wirsich
@jwirsich.bsky.social
EEG-fMRI, multimodal connectomics
Reposted by Jonathan Wirsich
Evidence from 14 research funding programmes confirms that early winners tend to keep winning (Matthew effect). But the idea that an early setback makes you stronger later doesn’t replicate widely.
buff.ly/UEtcRd4
buff.ly/UEtcRd4
November 12, 2025 at 4:15 PM
Evidence from 14 research funding programmes confirms that early winners tend to keep winning (Matthew effect). But the idea that an early setback makes you stronger later doesn’t replicate widely.
buff.ly/UEtcRd4
buff.ly/UEtcRd4
Check out our newest demonstrating feasabilty of sub-mm whole brain EEG-fMRI at 7T.
Happy to have been part of this amazing collaboration and thank you so much to Cristina and João for leading this project 😊👍.
Happy to have been part of this amazing collaboration and thank you so much to Cristina and João for leading this project 😊👍.
New paper in Imaging Neuroscience by C. Sainz Martinez, J. Jorge, et al:
An optimized framework for simultaneous EEG-fMRI at 7T enabling safe, high-quality human brain imaging with millisecond temporal resolution and sub-millimeter spatial resolution
doi.org/10.1162/IMAG...
An optimized framework for simultaneous EEG-fMRI at 7T enabling safe, high-quality human brain imaging with millisecond temporal resolution and sub-millimeter spatial resolution
doi.org/10.1162/IMAG...
November 7, 2025 at 9:06 AM
Check out our newest demonstrating feasabilty of sub-mm whole brain EEG-fMRI at 7T.
Happy to have been part of this amazing collaboration and thank you so much to Cristina and João for leading this project 😊👍.
Happy to have been part of this amazing collaboration and thank you so much to Cristina and João for leading this project 😊👍.
Reposted by Jonathan Wirsich
Is the the neuroimaging community (broadly conceived) submitting to 𝗡𝗲𝘂𝗿𝗼𝗶𝗺𝗮𝗴𝗲 again?????
Not to be publication police but the shift had seemed major 1-2 years ago.
Looking at the editorial board it seems to have serious scientists once more.
Curious about thoughts of the community.
Not to be publication police but the shift had seemed major 1-2 years ago.
Looking at the editorial board it seems to have serious scientists once more.
Curious about thoughts of the community.
October 21, 2025 at 4:16 PM
Is the the neuroimaging community (broadly conceived) submitting to 𝗡𝗲𝘂𝗿𝗼𝗶𝗺𝗮𝗴𝗲 again?????
Not to be publication police but the shift had seemed major 1-2 years ago.
Looking at the editorial board it seems to have serious scientists once more.
Curious about thoughts of the community.
Not to be publication police but the shift had seemed major 1-2 years ago.
Looking at the editorial board it seems to have serious scientists once more.
Curious about thoughts of the community.
Reposted by Jonathan Wirsich
Monty Python understood p-hacking
October 23, 2025 at 8:43 AM
Monty Python understood p-hacking
Reposted by Jonathan Wirsich
Enrico Amico and I have a project with competitively awarded studentships available through the MIBTP doctoral landscape award:
Decoding Human Thalamocortical Interactions with Invasive Electrophysiology
warwick.ac.uk/fac/cross_fa...
Please circulate and get in touch if interested.
Decoding Human Thalamocortical Interactions with Invasive Electrophysiology
warwick.ac.uk/fac/cross_fa...
Please circulate and get in touch if interested.
October 21, 2025 at 3:55 PM
Enrico Amico and I have a project with competitively awarded studentships available through the MIBTP doctoral landscape award:
Decoding Human Thalamocortical Interactions with Invasive Electrophysiology
warwick.ac.uk/fac/cross_fa...
Please circulate and get in touch if interested.
Decoding Human Thalamocortical Interactions with Invasive Electrophysiology
warwick.ac.uk/fac/cross_fa...
Please circulate and get in touch if interested.
Reposted by Jonathan Wirsich
Get ready for the biggest #ABIM yet! 🥳 We're celebrating our 20th anniversary with a special edition you won't want to miss.
🗓️ Registration & abstract submission: www.unige.ch/ABIM/partici...
💰Early bird fee ends November 9th!
#ABIM2026 #neuroimaging
🗓️ Registration & abstract submission: www.unige.ch/ABIM/partici...
💰Early bird fee ends November 9th!
#ABIM2026 #neuroimaging
October 14, 2025 at 1:53 PM
Get ready for the biggest #ABIM yet! 🥳 We're celebrating our 20th anniversary with a special edition you won't want to miss.
🗓️ Registration & abstract submission: www.unige.ch/ABIM/partici...
💰Early bird fee ends November 9th!
#ABIM2026 #neuroimaging
🗓️ Registration & abstract submission: www.unige.ch/ABIM/partici...
💰Early bird fee ends November 9th!
#ABIM2026 #neuroimaging
Reposted by Jonathan Wirsich
October 10, 2025 at 7:34 AM
Reposted by Jonathan Wirsich
A speech about what drives me, how science and open source are bitter victories, unable to make improve the world if society does not embrace them for the better:
gael-varoquaux.info/personnal/a-...
gael-varoquaux.info/personnal/a-...
A national recognition; but science and open source are bitter victories
I have recently been awarded France’s national order of merit, for my career, in science, in open source, and around AI. The speech that I gave carries messages important to me (French below;...
gael-varoquaux.info
October 10, 2025 at 11:37 AM
A speech about what drives me, how science and open source are bitter victories, unable to make improve the world if society does not embrace them for the better:
gael-varoquaux.info/personnal/a-...
gael-varoquaux.info/personnal/a-...
Reposted by Jonathan Wirsich
When @laurapritschet.bsky.social & Pavel Shapturenka set out to build the 28&Me + 28&He datasets, I don't think any of us could've predicted the spectacularly creative ways the datasets would be used years later. That's the power of open science. 👇🏼
October 3, 2025 at 8:00 PM
When @laurapritschet.bsky.social & Pavel Shapturenka set out to build the 28&Me + 28&He datasets, I don't think any of us could've predicted the spectacularly creative ways the datasets would be used years later. That's the power of open science. 👇🏼
Reposted by Jonathan Wirsich
#emotion
Armony, J., & Vuilleumier, P. (2025). The Cambridge handbook of human affective neuroscience (2nd ed.). Cambridge University Press. doi.org/10.1017/9781...
Armony, J., & Vuilleumier, P. (2025). The Cambridge handbook of human affective neuroscience (2nd ed.). Cambridge University Press. doi.org/10.1017/9781...
The Cambridge Handbook of Human Affective Neuroscience
Cambridge Core - Cognition - The Cambridge Handbook of Human Affective Neuroscience
doi.org
October 2, 2025 at 7:26 PM
#emotion
Armony, J., & Vuilleumier, P. (2025). The Cambridge handbook of human affective neuroscience (2nd ed.). Cambridge University Press. doi.org/10.1017/9781...
Armony, J., & Vuilleumier, P. (2025). The Cambridge handbook of human affective neuroscience (2nd ed.). Cambridge University Press. doi.org/10.1017/9781...
Reposted by Jonathan Wirsich
New layer-fMRI preprint using simultaneous layer-fMRI with EEG at 7T. Establishing an acquisition and analysis setup to capture layer-fMRI correlates of spontaneous alpha power variations.
By Marsh et al.
doi.org/10.1101/2025...
By Marsh et al.
doi.org/10.1101/2025...
October 2, 2025 at 1:08 PM
New layer-fMRI preprint using simultaneous layer-fMRI with EEG at 7T. Establishing an acquisition and analysis setup to capture layer-fMRI correlates of spontaneous alpha power variations.
By Marsh et al.
doi.org/10.1101/2025...
By Marsh et al.
doi.org/10.1101/2025...
Reposted by Jonathan Wirsich
Normative framework of bigger tech
(aka, me trolling the tech audience)
(aka, me trolling the tech audience)
Come to my lightning talk
At @pydataparis.bsky.social in a few minutes
At @pydataparis.bsky.social in a few minutes
October 1, 2025 at 4:42 PM
Normative framework of bigger tech
(aka, me trolling the tech audience)
(aka, me trolling the tech audience)
Reposted by Jonathan Wirsich
Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
September 30, 2025 at 7:39 PM
Ever wondered if your interesting brain-behavior correlation was over- or under-estimated due to head motion, but were afraid to ask? We’ve created a motion impact score for detecting spurious brain-behavior associations, now available in Nature Communications!
doi.org/10.1038/s414...
doi.org/10.1038/s414...
Reposted by Jonathan Wirsich
Excited to share such a career milestone 🌟 Our new @pnas.org paper shows how E–I balance drives dynamic brain adaptation.
Thanks to @jorgejovicich.bsky.social, @dimitrivdv.bsky.social, @asiaferrari.bsky.social, @bcassone.bsky.social & amazing co-authors 🙏
🔗 www.pnas.org/doi/10.1073/...
Thanks to @jorgejovicich.bsky.social, @dimitrivdv.bsky.social, @asiaferrari.bsky.social, @bcassone.bsky.social & amazing co-authors 🙏
🔗 www.pnas.org/doi/10.1073/...
Disentangling metabolic and neurovascular timescales supporting cognitive processes | PNAS
The balance between neural excitation and inhibition (EIB), governed by glutamatergic
and GABAergic neurotransmission, is an essential mechanism su...
www.pnas.org
September 24, 2025 at 7:41 AM
Excited to share such a career milestone 🌟 Our new @pnas.org paper shows how E–I balance drives dynamic brain adaptation.
Thanks to @jorgejovicich.bsky.social, @dimitrivdv.bsky.social, @asiaferrari.bsky.social, @bcassone.bsky.social & amazing co-authors 🙏
🔗 www.pnas.org/doi/10.1073/...
Thanks to @jorgejovicich.bsky.social, @dimitrivdv.bsky.social, @asiaferrari.bsky.social, @bcassone.bsky.social & amazing co-authors 🙏
🔗 www.pnas.org/doi/10.1073/...
Reposted by Jonathan Wirsich
Reposted by Jonathan Wirsich
This was my first paper with the new @elife.bsky.social model. Have to say, while I don't agree with all the reviewers' comments the new process is awesome. We can directly reply to their concerns and it'll be obvious what changed between revisions when we upload the revised version :) 4/4
September 16, 2025 at 6:45 AM
This was my first paper with the new @elife.bsky.social model. Have to say, while I don't agree with all the reviewers' comments the new process is awesome. We can directly reply to their concerns and it'll be obvious what changed between revisions when we upload the revised version :) 4/4
Reposted by Jonathan Wirsich
We are hiring !
👩🏼🎓👨🎓🧑🏼🎓👨🏿🎓👩🏿🎓👩🎓
I am looking for a motivated person interested in a PhD in basic neuroscience, for a project at the edge between epilepsy and sleep.
If you are interested, check the job announcement:
jobs.unige.ch/www/wd_porta...
👩🏼🎓👨🎓🧑🏼🎓👨🏿🎓👩🏿🎓👩🎓
I am looking for a motivated person interested in a PhD in basic neuroscience, for a project at the edge between epilepsy and sleep.
If you are interested, check the job announcement:
jobs.unige.ch/www/wd_porta...
Assistant-e (A2) (6548)
jobs.unige.ch
September 15, 2025 at 12:41 PM
We are hiring !
👩🏼🎓👨🎓🧑🏼🎓👨🏿🎓👩🏿🎓👩🎓
I am looking for a motivated person interested in a PhD in basic neuroscience, for a project at the edge between epilepsy and sleep.
If you are interested, check the job announcement:
jobs.unige.ch/www/wd_porta...
👩🏼🎓👨🎓🧑🏼🎓👨🏿🎓👩🏿🎓👩🎓
I am looking for a motivated person interested in a PhD in basic neuroscience, for a project at the edge between epilepsy and sleep.
If you are interested, check the job announcement:
jobs.unige.ch/www/wd_porta...
Reposted by Jonathan Wirsich
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
September 5, 2025 at 2:59 AM
Launched in 2023, Imaging Neuroscience is now firmly established, with full indexing (PubMed, etc.) and 700 papers to date.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
We're very happy to announce that we are able to reduce the APC to $1400.
Huge thanks to all authors, reviewers, editorial team+board, and MIT Press.
Reposted by Jonathan Wirsich
Our review discussing the potential use of laminar fMRI for probing the role of cortical layers in epileptic seizure propagation and spread as well as it possible future clinical applications out in Brain (well as accepted manuscript!)
academic.oup.com/brain/advanc...
academic.oup.com/brain/advanc...
The potential of laminar functional MRI in refining the understanding of epilepsy in humans
Aitken et al. highlight laminar fMRI as a tool to connect the neural effects of anti-seizure medications with the microcircuits that generate seizures in e
academic.oup.com
September 3, 2025 at 7:24 PM
Our review discussing the potential use of laminar fMRI for probing the role of cortical layers in epileptic seizure propagation and spread as well as it possible future clinical applications out in Brain (well as accepted manuscript!)
academic.oup.com/brain/advanc...
academic.oup.com/brain/advanc...
Reposted by Jonathan Wirsich
Happy to see this out: our new preprint shows that laminar GE-BOLD fMRI decoding isn’t immune to vascular draining biases. Simulations reveal false positives due to multivariate signal spread across layers, but oversampling + deconvolution can (sometimes) improve specificity.
Vascular draining confounds laminar decoding in fMRI https://www.biorxiv.org/content/10.1101/2025.08.26.672278v1
August 30, 2025 at 2:28 PM
Happy to see this out: our new preprint shows that laminar GE-BOLD fMRI decoding isn’t immune to vascular draining biases. Simulations reveal false positives due to multivariate signal spread across layers, but oversampling + deconvolution can (sometimes) improve specificity.
Reposted by Jonathan Wirsich
New paper🥳
🧠 In TLE, brain changes go beyond the temporal lobe & beyond normal aging.
Our ENIGMA study (769 patients, 18 sites) found widespread gray & white matter decline, especially after 55. By Judy Chen and a terrific intl' team
Time for earlier diagnosis & deeper research
bit.ly/3HRYeQt
🧠 In TLE, brain changes go beyond the temporal lobe & beyond normal aging.
Our ENIGMA study (769 patients, 18 sites) found widespread gray & white matter decline, especially after 55. By Judy Chen and a terrific intl' team
Time for earlier diagnosis & deeper research
bit.ly/3HRYeQt
August 24, 2025 at 6:05 PM
New paper🥳
🧠 In TLE, brain changes go beyond the temporal lobe & beyond normal aging.
Our ENIGMA study (769 patients, 18 sites) found widespread gray & white matter decline, especially after 55. By Judy Chen and a terrific intl' team
Time for earlier diagnosis & deeper research
bit.ly/3HRYeQt
🧠 In TLE, brain changes go beyond the temporal lobe & beyond normal aging.
Our ENIGMA study (769 patients, 18 sites) found widespread gray & white matter decline, especially after 55. By Judy Chen and a terrific intl' team
Time for earlier diagnosis & deeper research
bit.ly/3HRYeQt
Interested in Epileptic Discharges? In need of a data set to validate your source reconstruction models based on clinical outcome? Check out our newest: www.nature.com/articles/s41...
Big thanks to B. Vorderwülbecke, S. Vuillémoz et al. ! - @seeber.bsky.social @cibm.bsky.social
Big thanks to B. Vorderwülbecke, S. Vuillémoz et al. ! - @seeber.bsky.social @cibm.bsky.social
High-Density EEG Source Localisation of averaged interictal epileptic Discharges validated by surgical Outcome - Scientific Data
Scientific Data - High-Density EEG Source Localisation of averaged interictal epileptic Discharges validated by surgical Outcome
www.nature.com
August 18, 2025 at 11:33 AM
Interested in Epileptic Discharges? In need of a data set to validate your source reconstruction models based on clinical outcome? Check out our newest: www.nature.com/articles/s41...
Big thanks to B. Vorderwülbecke, S. Vuillémoz et al. ! - @seeber.bsky.social @cibm.bsky.social
Big thanks to B. Vorderwülbecke, S. Vuillémoz et al. ! - @seeber.bsky.social @cibm.bsky.social
Reposted by Jonathan Wirsich
In 2019, the CNeuroMod team and 6 participants began a massive data collection journey: twice-weekly MRI scans for most of 5 years. Data collection is now complete! 1/🧵
August 7, 2025 at 8:30 PM
In 2019, the CNeuroMod team and 6 participants began a massive data collection journey: twice-weekly MRI scans for most of 5 years. Data collection is now complete! 1/🧵
Reposted by Jonathan Wirsich
5. It has been centuries since any one human could know everything that is known; understand everything that is understood.
This is a remarkable power of science. We delegate trust and authority to experts as internally established in ways that are remarkably resilient to mistakes and malfeasance.
This is a remarkable power of science. We delegate trust and authority to experts as internally established in ways that are remarkably resilient to mistakes and malfeasance.
August 12, 2025 at 5:00 AM
5. It has been centuries since any one human could know everything that is known; understand everything that is understood.
This is a remarkable power of science. We delegate trust and authority to experts as internally established in ways that are remarkably resilient to mistakes and malfeasance.
This is a remarkable power of science. We delegate trust and authority to experts as internally established in ways that are remarkably resilient to mistakes and malfeasance.
Reposted by Jonathan Wirsich
Thanks to all (co)authors & reviewers for their contribution to this study on #layer specific changes in #sensory #cortex across the #lifespan in #humans & #mice now out in @natneuro.nature.com Here is a short summary of our findings 1/6
🧠 The human brain ages less than thought and in layers – at least in the area of the cortex responsible for the sense of touch. See study @natneuro.nature.com by @estherkuehn.bsky.social and colleagues at DZNE, @hih-tuebingen.bsky.social and @uni-magdeburg.de:
👉 www.nature.com/articles/s41...
👉 www.nature.com/articles/s41...
Layer-specific changes in sensory cortex across the lifespan in mice and humans - Nature Neuroscience
The principal layer architecture of the sensory cortex is altered with aging. The authors show that overall thinning of the primary somatosensory cortex is driven by deep layer degeneration but that l...
www.nature.com
August 11, 2025 at 2:29 PM