Juan C. Landoni 🔬
@jclandoni.bsky.social
Mitochondriac 🔬 Postdoc @EPFL Manley lab of Experimental Biophysics 🧪 Ph.D. @HelsinkiUni 🇦🇷🇫🇮🇪🇺🇨🇭🏳️🌈 (he/él)
linktr.ee/jclandoni
linktr.ee/jclandoni
Pinned
Juan C. Landoni 🔬
@jclandoni.bsky.social
· Dec 23
Stoked to share TWO preprints on mitochondrial pearling! 🎉
We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024...), and
@gavsturm.bsky.social
et al. dissect the biophysics behind it (doi.org/10.1101/2024...). Details below! 🔬🧵🧪
We uncover how spontaneous #mitochondria pearling drives #mtDNA nucleoid distribution (doi.org/10.1101/2024...), and
@gavsturm.bsky.social
et al. dissect the biophysics behind it (doi.org/10.1101/2024...). Details below! 🔬🧵🧪
It's not #FluorescenceFriday but unexpectedly beautiful data should always be celebrated 💚 #PKMO -stained #mitochondria cristae in #STED
November 25, 2025 at 12:56 PM
It's not #FluorescenceFriday but unexpectedly beautiful data should always be celebrated 💚 #PKMO -stained #mitochondria cristae in #STED
Another year and another group of brilliant young students preparing for the International Biology Olympiad #IBO 💪☘️
Thank you for making teaching so fun and inspiring, bon courage à tous, and most importantly: enjoy it!
Thank you for making teaching so fun and inspiring, bon courage à tous, and most importantly: enjoy it!
November 21, 2025 at 10:01 AM
Another year and another group of brilliant young students preparing for the International Biology Olympiad #IBO 💪☘️
Thank you for making teaching so fun and inspiring, bon courage à tous, and most importantly: enjoy it!
Thank you for making teaching so fun and inspiring, bon courage à tous, and most importantly: enjoy it!
Reposted by Juan C. Landoni 🔬
#StarterPack for the #Mitochondria research community! Very much a work in progress, comment below/reach out to be added!
#Mito #Mitochondriac
go.bsky.app/J6Bu5fL
#Mito #Mitochondriac
go.bsky.app/J6Bu5fL
November 12, 2024 at 6:35 PM
#StarterPack for the #Mitochondria research community! Very much a work in progress, comment below/reach out to be added!
#Mito #Mitochondriac
go.bsky.app/J6Bu5fL
#Mito #Mitochondriac
go.bsky.app/J6Bu5fL
Smartest booth luring strategy I've seen: a pro barista on site 🤯
Drop the free pens. Science runs on espresso ☕️
Drop the free pens. Science runs on espresso ☕️
November 6, 2025 at 12:24 PM
Smartest booth luring strategy I've seen: a pro barista on site 🤯
Drop the free pens. Science runs on espresso ☕️
Drop the free pens. Science runs on espresso ☕️
That's a wrap on a much-needed family vacay, thank you Costa Rica for your incredible nature 🌋🦥🏞️🐠🐡🐒🦈, now back to our regularly scheduled programming 🔬
October 27, 2025 at 3:31 PM
That's a wrap on a much-needed family vacay, thank you Costa Rica for your incredible nature 🌋🦥🏞️🐠🐡🐒🦈, now back to our regularly scheduled programming 🔬
Reposted by Juan C. Landoni 🔬
New paper - MAPL strikes again! Interested in mitochondrial signalling, inflammation, lysosome biology, pyroptosis, and Parkinson's disease? Have a look, there's something for everyone! Feeling grateful! @mitocollier.bsky.social Funded by #CIHR, @asapresearch.parkinsonsroadmap.org.
rdcu.be/eKKz1 🇨🇦
rdcu.be/eKKz1 🇨🇦
October 14, 2025 at 11:50 AM
New paper - MAPL strikes again! Interested in mitochondrial signalling, inflammation, lysosome biology, pyroptosis, and Parkinson's disease? Have a look, there's something for everyone! Feeling grateful! @mitocollier.bsky.social Funded by #CIHR, @asapresearch.parkinsonsroadmap.org.
rdcu.be/eKKz1 🇨🇦
rdcu.be/eKKz1 🇨🇦
Reposted by Juan C. Landoni 🔬
What complex are you if you have a very versatile company in close proximity? The MICOS Complex.
We present the MINDNet: Proximity Proteomics revealing the nanodomain interactome in the mitochondrial inner membrane, done by the talented Yulia and team.
We present the MINDNet: Proximity Proteomics revealing the nanodomain interactome in the mitochondrial inner membrane, done by the talented Yulia and team.
MINDNet: Proximity interactome of the MICOS complex revealing a multifaceted network orchestrating mitochondrial biogenesis https://www.biorxiv.org/content/10.1101/2025.05.20.655052v1
May 21, 2025 at 6:29 PM
What complex are you if you have a very versatile company in close proximity? The MICOS Complex.
We present the MINDNet: Proximity Proteomics revealing the nanodomain interactome in the mitochondrial inner membrane, done by the talented Yulia and team.
We present the MINDNet: Proximity Proteomics revealing the nanodomain interactome in the mitochondrial inner membrane, done by the talented Yulia and team.
Still buzzing from the incomparable @embl.org #SeeingisBelieving conference! 🔬
Great science and truly amazing people, thanks everyone!
#EESImaging
Great science and truly amazing people, thanks everyone!
#EESImaging
October 14, 2025 at 7:32 PM
Still buzzing from the incomparable @embl.org #SeeingisBelieving conference! 🔬
Great science and truly amazing people, thanks everyone!
#EESImaging
Great science and truly amazing people, thanks everyone!
#EESImaging
📣 Do you want to be part of #EESImaging, the exciting symposium that brings together leading innovators in imaging technologies and biological applications?
Then hurry up and submit your abstract! The deadline is tomorrow ⏰ https://s.embl.org/ees25-09-bl
Then hurry up and submit your abstract! The deadline is tomorrow ⏰ https://s.embl.org/ees25-09-bl
October 4, 2025 at 10:01 AM
Reposted by Juan C. Landoni 🔬
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
Mechano-osmotic signals control chromatin state and fate transitions in pluripotent stem cells - Nature Cell Biology
McCreery, Stubb et al. show that mechano-osmotic changes in the nucleus induce general transcriptional repression and prime chromatin for cell fate transitions by relieving repression of specific differentiation genes.
www.nature.com
September 29, 2025 at 4:45 PM
How do #stemcells integrate information to coordinate fate decisions? Delighted to finally see our work showing how growth factors regulate the mechano-osmotic state of the #nucleus and #chromatin to control #pluripotency exit out! www.nature.com/articles/s41... see 🧵 👇
Reposted by Juan C. Landoni 🔬
From MBoC: Wallace F. Marshall (UCSF) and team profile the giant ciliate Stentor pyriformis—symbiotic algae in microtubule baskets, symbiont-dependent phototaxis, and a standard genetic code. Paper: www.molbiolcell.org/doi/10.1091/... #CellBiology
September 19, 2025 at 12:02 PM
From MBoC: Wallace F. Marshall (UCSF) and team profile the giant ciliate Stentor pyriformis—symbiotic algae in microtubule baskets, symbiont-dependent phototaxis, and a standard genetic code. Paper: www.molbiolcell.org/doi/10.1091/... #CellBiology
"Who needs a 30x zoom anyway?"
I just found out the answer 🌙🤩
I just found out the answer 🌙🤩
September 7, 2025 at 7:15 PM
"Who needs a 30x zoom anyway?"
I just found out the answer 🌙🤩
I just found out the answer 🌙🤩
August 26, 2025 at 3:04 PM
Trying my hand at HTML/CSS using @github.com hosting for a new personal website 💻 Highly recommend!
jclandoni.github.io
Comments/tips welcome (should look nicer on desktop but mobile should work too).
jclandoni.github.io
Comments/tips welcome (should look nicer on desktop but mobile should work too).
August 25, 2025 at 11:52 AM
Trying my hand at HTML/CSS using @github.com hosting for a new personal website 💻 Highly recommend!
jclandoni.github.io
Comments/tips welcome (should look nicer on desktop but mobile should work too).
jclandoni.github.io
Comments/tips welcome (should look nicer on desktop but mobile should work too).
August 22, 2025 at 10:57 AM
So excited to follow the opening symposium of #SWAN 🦢[Sustainable Wellbeing Across Lifespan] at @helsinki.fi today! Congrats to @awartiovaara.bsky.social and all members for the exciting ongoing and future reseach!
#mitochondria #metabolism #aging #health
#mitochondria #metabolism #aging #health
August 20, 2025 at 12:43 PM
So excited to follow the opening symposium of #SWAN 🦢[Sustainable Wellbeing Across Lifespan] at @helsinki.fi today! Congrats to @awartiovaara.bsky.social and all members for the exciting ongoing and future reseach!
#mitochondria #metabolism #aging #health
#mitochondria #metabolism #aging #health
August 19, 2025 at 2:42 PM
Reposted by Juan C. Landoni 🔬
🐟 Zebrafish (Danio rerio): Clear as glass, zebrafish embryos let you watch organs form in real time. A powerhouse for studying organogenesis and regeneration, they’re also champions of transgenic expression of fluorescent proteins 🌈 image from Gopi Shah 🧪 #ModelMonday #DevBio
August 18, 2025 at 5:07 PM
🐟 Zebrafish (Danio rerio): Clear as glass, zebrafish embryos let you watch organs form in real time. A powerhouse for studying organogenesis and regeneration, they’re also champions of transgenic expression of fluorescent proteins 🌈 image from Gopi Shah 🧪 #ModelMonday #DevBio
In case you haven't heard, #Argentinian scientists are live-streaming their deep-sea mission with real-time interactive commentary.
It's genius, mesmerising, and triggering huge public interest and support for #science funding 🐙🧪 And the memes are great! #CONICET #MarDelPlataCanyon
It's genius, mesmerising, and triggering huge public interest and support for #science funding 🐙🧪 And the memes are great! #CONICET #MarDelPlataCanyon
August 6, 2025 at 8:32 AM
In case you haven't heard, #Argentinian scientists are live-streaming their deep-sea mission with real-time interactive commentary.
It's genius, mesmerising, and triggering huge public interest and support for #science funding 🐙🧪 And the memes are great! #CONICET #MarDelPlataCanyon
It's genius, mesmerising, and triggering huge public interest and support for #science funding 🐙🧪 And the memes are great! #CONICET #MarDelPlataCanyon
Reposted by Juan C. Landoni 🔬
Here it is❗️Our updated inventory of genes required for #OXPHOS & findings on #mito defects in #Menieres is now out at Cell Reports by Cell Press! 🎉
Thank you to all of our collaborators and funding sources, this was a great and exciting project from start to finish. 💫
www.cell.com/cell-reports...
Thank you to all of our collaborators and funding sources, this was a great and exciting project from start to finish. 💫
www.cell.com/cell-reports...
An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière’s disease
Harhai and collaborators expand the catalog of genes essential for oxidative phosphorylation
and implicate FAM136A in mitochondrial proteostasis. Their findings suggest a mitochondrial
contribution to...
www.cell.com
July 28, 2025 at 7:17 AM
Here it is❗️Our updated inventory of genes required for #OXPHOS & findings on #mito defects in #Menieres is now out at Cell Reports by Cell Press! 🎉
Thank you to all of our collaborators and funding sources, this was a great and exciting project from start to finish. 💫
www.cell.com/cell-reports...
Thank you to all of our collaborators and funding sources, this was a great and exciting project from start to finish. 💫
www.cell.com/cell-reports...
Reposted by Juan C. Landoni 🔬
Our updated inventory of genes required for #OXPHOS & findings on #mito defects in #Menieres is now out at Cell Reports! 🎉
🧫 New galactose #CRISPR screen
🎯 481 genes required for #OXPHOS
⚙️ #FAM136A in IMS proteostasis
👂 Mito defects in #Menieres
www.cell.com/cell-reports...
🧫 New galactose #CRISPR screen
🎯 481 genes required for #OXPHOS
⚙️ #FAM136A in IMS proteostasis
👂 Mito defects in #Menieres
www.cell.com/cell-reports...
An updated inventory of genes essential for oxidative phosphorylation identifies a mitochondrial origin in familial Ménière’s disease
Harhai and collaborators expand the catalog of genes essential for oxidative phosphorylation
and implicate FAM136A in mitochondrial proteostasis. Their findings suggest a mitochondrial
contribution to...
www.cell.com
July 28, 2025 at 5:40 AM
Reposted by Juan C. Landoni 🔬
Congrats to PhD student @marcellharhai.bsky.social , who joined the lab 2y ago (!) and led this work, to second author M. Foged, and to all our collaborators!
We are thankful to our funding sources including the @FSRMM, Novartis and @snsf.ch.
@dib-unil.bsky.social @fbm-unil.bsky.social
We are thankful to our funding sources including the @FSRMM, Novartis and @snsf.ch.
@dib-unil.bsky.social @fbm-unil.bsky.social
July 28, 2025 at 5:40 AM
Congrats to PhD student @marcellharhai.bsky.social , who joined the lab 2y ago (!) and led this work, to second author M. Foged, and to all our collaborators!
We are thankful to our funding sources including the @FSRMM, Novartis and @snsf.ch.
@dib-unil.bsky.social @fbm-unil.bsky.social
We are thankful to our funding sources including the @FSRMM, Novartis and @snsf.ch.
@dib-unil.bsky.social @fbm-unil.bsky.social
Reposted by Juan C. Landoni 🔬
Join us in Engelberg for an exciting #EMBO workshop on #mitochondria in the nervous system #EMBOmitoNervousSys. Great speaker line up and opportunities for short talks from early career scientists!
Submit your abstract until May 30st!
meetings.embo.org/event/25-mit...
Submit your abstract until May 30st!
meetings.embo.org/event/25-mit...
April 14, 2025 at 8:48 AM
Join us in Engelberg for an exciting #EMBO workshop on #mitochondria in the nervous system #EMBOmitoNervousSys. Great speaker line up and opportunities for short talks from early career scientists!
Submit your abstract until May 30st!
meetings.embo.org/event/25-mit...
Submit your abstract until May 30st!
meetings.embo.org/event/25-mit...
Is there still a reason for dumping figures at the end of manuscripts instead of in-text, even for #BioRxiv preprints? My scroll-finger is exhausted... 🙏🧪📜
May 1, 2025 at 7:59 AM
Is there still a reason for dumping figures at the end of manuscripts instead of in-text, even for #BioRxiv preprints? My scroll-finger is exhausted... 🙏🧪📜