ImmuNoah's Ark (Noe Rodriguez)
@immunoah.bsky.social
Group Leader @MRC LMB. Passionate about (neuro)immunology, the universe & every now & then some good old fashion fantasy🏳️🌈(he/him). Opinions are my own.
https://www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/noe-rodriguez/
https://orcid.org/0000-0001-7825-5634
https://www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/noe-rodriguez/
https://orcid.org/0000-0001-7825-5634
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Decisiveness is key for being a good editor.
Journal editors, if you put anyone through 2-3 revisions, that should be enough for you to show some gosh darned leadership and either decide (a) it is publishable without further review, or (b) it will not be published in your journal, and it's only fair to tell the authors so.
a woman says it 's time to make some decisions up here
Alt: Lizzo, looking glorious in gold velvet, says it's time to make some decisions up in here
media.tenor.com
November 23, 2025 at 2:34 PM
Decisiveness is key for being a good editor.
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Bad antibodies are a major roadblock in biomedical research, harming reproducibility and wasting resources.
The International Antibody Validation Meeting was created to fix it.
Watch the talks from the 5th Antibody Validation Meeting (2025)
tinyurl.com/AntibodyVali...
#Integrity #reproducibility
The International Antibody Validation Meeting was created to fix it.
Watch the talks from the 5th Antibody Validation Meeting (2025)
tinyurl.com/AntibodyVali...
#Integrity #reproducibility
5th International Antibody Validation Meeting - YouTube
Listen to talks from the speakers at the 5th AbVal meeting, held in Bath on the 9-11th September 2025.
tinyurl.com
November 22, 2025 at 10:57 AM
Bad antibodies are a major roadblock in biomedical research, harming reproducibility and wasting resources.
The International Antibody Validation Meeting was created to fix it.
Watch the talks from the 5th Antibody Validation Meeting (2025)
tinyurl.com/AntibodyVali...
#Integrity #reproducibility
The International Antibody Validation Meeting was created to fix it.
Watch the talks from the 5th Antibody Validation Meeting (2025)
tinyurl.com/AntibodyVali...
#Integrity #reproducibility
Reposted by ImmuNoah's Ark (Noe Rodriguez)
How do cytokines shape immune cells?
We analyzed and visualized Parse Bio's 10M PBMC dataset to give researchers a powerful tool for exploring the dynamics between cytokines & peripheral blood mononuclear cells.
More: https://apps.allenimmunology.org/aifi/resources/parse-10m-cytokines/
#ImmunoSky
We analyzed and visualized Parse Bio's 10M PBMC dataset to give researchers a powerful tool for exploring the dynamics between cytokines & peripheral blood mononuclear cells.
More: https://apps.allenimmunology.org/aifi/resources/parse-10m-cytokines/
#ImmunoSky
November 21, 2025 at 3:57 PM
How do cytokines shape immune cells?
We analyzed and visualized Parse Bio's 10M PBMC dataset to give researchers a powerful tool for exploring the dynamics between cytokines & peripheral blood mononuclear cells.
More: https://apps.allenimmunology.org/aifi/resources/parse-10m-cytokines/
#ImmunoSky
We analyzed and visualized Parse Bio's 10M PBMC dataset to give researchers a powerful tool for exploring the dynamics between cytokines & peripheral blood mononuclear cells.
More: https://apps.allenimmunology.org/aifi/resources/parse-10m-cytokines/
#ImmunoSky
Reposted by ImmuNoah's Ark (Noe Rodriguez)
You read what you can, with an honest attempt at being comprehensive. If you missed something, hopefully the editors/reviewers will point it out. If they don't, well, it happens; a reader or the authors might mention it, and now you know.
We haven't been able to "read everything" for many years.
We haven't been able to "read everything" for many years.
How do we make sense of scientific literature that is growing explosively to the point where no-one could read all the relevant papers, and is contaminated with fraudulent and LLM-generated papers? I think that science isn't currently equipped to deal with this, and we need to. #science #metascience
November 21, 2025 at 1:59 PM
You read what you can, with an honest attempt at being comprehensive. If you missed something, hopefully the editors/reviewers will point it out. If they don't, well, it happens; a reader or the authors might mention it, and now you know.
We haven't been able to "read everything" for many years.
We haven't been able to "read everything" for many years.
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Earlier this year, the LMB was thrilled to appoint Csilla Biro as the new Domestic Services Manager, overseeing cleaning and waste disposal services across the LMB.
Read more about Csilla and the team here: www2.mrc-lmb.cam.ac.uk/csilla-biro-...
#LMBNews
Read more about Csilla and the team here: www2.mrc-lmb.cam.ac.uk/csilla-biro-...
#LMBNews
November 20, 2025 at 10:32 AM
Earlier this year, the LMB was thrilled to appoint Csilla Biro as the new Domestic Services Manager, overseeing cleaning and waste disposal services across the LMB.
Read more about Csilla and the team here: www2.mrc-lmb.cam.ac.uk/csilla-biro-...
#LMBNews
Read more about Csilla and the team here: www2.mrc-lmb.cam.ac.uk/csilla-biro-...
#LMBNews
Reposted by ImmuNoah's Ark (Noe Rodriguez)
November 18, 2025 at 4:00 PM
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Want to join the LMB as a PhD student in October 2026?
You’ve got two weeks left to apply!
Visit our website for more details: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd December 2025.
You’ve got two weeks left to apply!
Visit our website for more details: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd December 2025.
November 18, 2025 at 2:29 PM
Want to join the LMB as a PhD student in October 2026?
You’ve got two weeks left to apply!
Visit our website for more details: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd December 2025.
You’ve got two weeks left to apply!
Visit our website for more details: www2.mrc-lmb.cam.ac.uk/students/int...
Applications close on 2nd December 2025.
Reposted by ImmuNoah's Ark (Noe Rodriguez)
How is the integrated stress response terminated?
@annebertolotti.bsky.social’s group have revealed the mechanism of termination of the ISR, answering a decades-old question surrounding the ISR pathway, which is crucial to cellular homeostasis.
www2.mrc-lmb.cam.ac.uk/how-is-the-i...
#LMBReserch
@annebertolotti.bsky.social’s group have revealed the mechanism of termination of the ISR, answering a decades-old question surrounding the ISR pathway, which is crucial to cellular homeostasis.
www2.mrc-lmb.cam.ac.uk/how-is-the-i...
#LMBReserch
November 14, 2025 at 9:30 AM
How is the integrated stress response terminated?
@annebertolotti.bsky.social’s group have revealed the mechanism of termination of the ISR, answering a decades-old question surrounding the ISR pathway, which is crucial to cellular homeostasis.
www2.mrc-lmb.cam.ac.uk/how-is-the-i...
#LMBReserch
@annebertolotti.bsky.social’s group have revealed the mechanism of termination of the ISR, answering a decades-old question surrounding the ISR pathway, which is crucial to cellular homeostasis.
www2.mrc-lmb.cam.ac.uk/how-is-the-i...
#LMBReserch
Definitely not the acknowledgement I was expecting when @dannbiostda.bsky.social told me about it (tbh I was not expecting any), but you are more than welcome! 🤣🤩
Congrats on the paper!
Congrats on the paper!
November 10, 2025 at 7:21 PM
Definitely not the acknowledgement I was expecting when @dannbiostda.bsky.social told me about it (tbh I was not expecting any), but you are more than welcome! 🤣🤩
Congrats on the paper!
Congrats on the paper!
Reposted by ImmuNoah's Ark (Noe Rodriguez)
GPR34 is a splenic cDC1 receptor that is required for efferocytosis and for the cross-presentation of apoptotic cell–associated antigen to CD8 T cells @jem.org
rupress.org/jem/article/...
rupress.org/jem/article/...
November 10, 2025 at 5:59 PM
GPR34 is a splenic cDC1 receptor that is required for efferocytosis and for the cross-presentation of apoptotic cell–associated antigen to CD8 T cells @jem.org
rupress.org/jem/article/...
rupress.org/jem/article/...
I had not had a chance to read the paper until now. Now I can say it is even cooler than I had anticipated. Congrats to all the authors.
Thus: Genetic/pharmacological modulation demonstrates GPR68’s role in acid-induced colonic nociception, supporting its therapeutic potential for pain management in colitis.
November 8, 2025 at 11:55 AM
I had not had a chance to read the paper until now. Now I can say it is even cooler than I had anticipated. Congrats to all the authors.
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Acid-induced pain is complex: there are LOTS of acid sensors; acid-induced pain is common in the animal kingdom, but not naked mole-rats, see @interlukein.bsky.social’s review royalsocietypublishing.org/doi/10.1098/...
November 4, 2025 at 4:49 PM
Acid-induced pain is complex: there are LOTS of acid sensors; acid-induced pain is common in the animal kingdom, but not naked mole-rats, see @interlukein.bsky.social’s review royalsocietypublishing.org/doi/10.1098/...
Reposted by ImmuNoah's Ark (Noe Rodriguez)
This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
November 7, 2025 at 1:35 PM
This is a glimpse of the cytoskeletal structures we found doing U-ExM in more than 200 species, now in Cell🤩: shorturl.at/6oHvi
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
Amazing collaboration between @centriolelab.bsky.social , @dudinlab.bsky.social and @gautamdey.bsky.social labs.
I believe last one is a 🕷️
#FluorescenceFriday
#Microscopy
Reposted by ImmuNoah's Ark (Noe Rodriguez)
LMB scientists showcased their research at the @pborostemfest.bsky.social with hands-on activities focused on the microscopic world 🔬
Read about the event here: www2.mrc-lmb.cam.ac.uk/peterborough... #LMBNews
#PeterboroughSTEMFestival
Read about the event here: www2.mrc-lmb.cam.ac.uk/peterborough... #LMBNews
#PeterboroughSTEMFestival
November 6, 2025 at 9:51 AM
LMB scientists showcased their research at the @pborostemfest.bsky.social with hands-on activities focused on the microscopic world 🔬
Read about the event here: www2.mrc-lmb.cam.ac.uk/peterborough... #LMBNews
#PeterboroughSTEMFestival
Read about the event here: www2.mrc-lmb.cam.ac.uk/peterborough... #LMBNews
#PeterboroughSTEMFestival
Reposted by ImmuNoah's Ark (Noe Rodriguez)
TODAY@16:00 CET: How do scientists make policy impact?
Go beyond data: engage with the values the motivate decisions
Join myself (EGU) & Mario Scharfbillig (EU Commission) as we explore strategies to help your message resonate with policy-makers
www.egu.eu/webinars/564...
#Science4Policy #SciComm
Go beyond data: engage with the values the motivate decisions
Join myself (EGU) & Mario Scharfbillig (EU Commission) as we explore strategies to help your message resonate with policy-makers
www.egu.eu/webinars/564...
#Science4Policy #SciComm
www.egu.eu
November 6, 2025 at 9:44 AM
TODAY@16:00 CET: How do scientists make policy impact?
Go beyond data: engage with the values the motivate decisions
Join myself (EGU) & Mario Scharfbillig (EU Commission) as we explore strategies to help your message resonate with policy-makers
www.egu.eu/webinars/564...
#Science4Policy #SciComm
Go beyond data: engage with the values the motivate decisions
Join myself (EGU) & Mario Scharfbillig (EU Commission) as we explore strategies to help your message resonate with policy-makers
www.egu.eu/webinars/564...
#Science4Policy #SciComm
Reposted by ImmuNoah's Ark (Noe Rodriguez)
AAI Member Elizabeth Delery shared a video explaining how the flu shot works and why as an immunologist, she gets her flu shot every year. Follow #ImmunologyExplained on Instagram, Facebook, or TikTok to see the full video and share it with your network!
October 30, 2025 at 12:17 PM
AAI Member Elizabeth Delery shared a video explaining how the flu shot works and why as an immunologist, she gets her flu shot every year. Follow #ImmunologyExplained on Instagram, Facebook, or TikTok to see the full video and share it with your network!
Reposted by ImmuNoah's Ark (Noe Rodriguez)
How can public engagement transform how we teach #Immunology?
Join this parallel session organised by the BSI Teaching Affinity Group at BSI Congress to explore how collaboration and lived experience enrich education & research.
Register for #BSI25: https://bit.ly/3IkxWq8
Join this parallel session organised by the BSI Teaching Affinity Group at BSI Congress to explore how collaboration and lived experience enrich education & research.
Register for #BSI25: https://bit.ly/3IkxWq8
November 5, 2025 at 11:35 AM
How can public engagement transform how we teach #Immunology?
Join this parallel session organised by the BSI Teaching Affinity Group at BSI Congress to explore how collaboration and lived experience enrich education & research.
Register for #BSI25: https://bit.ly/3IkxWq8
Join this parallel session organised by the BSI Teaching Affinity Group at BSI Congress to explore how collaboration and lived experience enrich education & research.
Register for #BSI25: https://bit.ly/3IkxWq8
Reposted by ImmuNoah's Ark (Noe Rodriguez)
A new #PainResearch paper from us at @phar.cam.ac.uk 😃 Led by Luke Paine from the Bulmer Lab, supported by @javimmunopain.bsky.social & others, & it’s all about acid; not the hallucinogenic kind, but rather H+ www.cmghjournal.org/article/S235...
GPR68, a proton-sensing GPCR, mediates acid-induced visceral nociception
Localised acidification from immune cell infiltration and heightened glycolysis contributes
to colitis pathology by activating acid-sensing receptors such as GPR68, a proton-sensing
GPCR expressed on ...
www.cmghjournal.org
November 4, 2025 at 4:49 PM
A new #PainResearch paper from us at @phar.cam.ac.uk 😃 Led by Luke Paine from the Bulmer Lab, supported by @javimmunopain.bsky.social & others, & it’s all about acid; not the hallucinogenic kind, but rather H+ www.cmghjournal.org/article/S235...
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Statistical thinking is a core part of solid biological results. However, many studies still include insufficient sample sizes, have poor experimental design, or select incorrect statistical tests.
Here, the authors present ten statistical tips for cell biology
www.nature.com/articles/s41...
Here, the authors present ten statistical tips for cell biology
www.nature.com/articles/s41...
Ten essential tips for robust statistics in cell biology - Nature Cell Biology
Statistical thinking is a core part of solid, trustworthy biology. However, many studies still include insufficient sample sizes, have poor experimental design or select an incorrect statistical metho...
www.nature.com
November 4, 2025 at 7:52 PM
Statistical thinking is a core part of solid biological results. However, many studies still include insufficient sample sizes, have poor experimental design, or select incorrect statistical tests.
Here, the authors present ten statistical tips for cell biology
www.nature.com/articles/s41...
Here, the authors present ten statistical tips for cell biology
www.nature.com/articles/s41...
Reposted by ImmuNoah's Ark (Noe Rodriguez)
'When Mendel began his investigation, his first inclination was to try breeding mice of different colors. However, before his mice experiment really got going, Mendel was forced to switch the subject of his experiments to peas by a prudish bishop uncomfortable with animals having sex in the abbey.'
Origins of the Lab Mouse
How the mouse found its way from Victorian novelty to a biomedical mainstay.
www.asimov.press
November 3, 2025 at 6:25 PM
'When Mendel began his investigation, his first inclination was to try breeding mice of different colors. However, before his mice experiment really got going, Mendel was forced to switch the subject of his experiments to peas by a prudish bishop uncomfortable with animals having sex in the abbey.'
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Last chance to apply - closing Nov 3rd: www.jobs.cam.ac.uk/job/52936/ Consider coming to Cambridge to work on a highly collaborative project on lung stem cells and lung disease with @labrawlins.bsky.social and @jennydickens41.bsky.social
October 31, 2025 at 4:29 PM
Last chance to apply - closing Nov 3rd: www.jobs.cam.ac.uk/job/52936/ Consider coming to Cambridge to work on a highly collaborative project on lung stem cells and lung disease with @labrawlins.bsky.social and @jennydickens41.bsky.social
NK cell definitely as a Jedi:
Travelling the Galaxy (BM to Liver and beyond)
Innately sensing the force (Receptors & antigens on other cells)
Controlling it (IFNg secretion)
Wielding a lightsaber (cytotoxic granules)
....If they embrace the dark side, immunopathology 👻
Travelling the Galaxy (BM to Liver and beyond)
Innately sensing the force (Receptors & antigens on other cells)
Controlling it (IFNg secretion)
Wielding a lightsaber (cytotoxic granules)
....If they embrace the dark side, immunopathology 👻
🎃 Happy Halloween! Ever wondered what your immune cells would wear to a costume party?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
October 31, 2025 at 5:58 PM
NK cell definitely as a Jedi:
Travelling the Galaxy (BM to Liver and beyond)
Innately sensing the force (Receptors & antigens on other cells)
Controlling it (IFNg secretion)
Wielding a lightsaber (cytotoxic granules)
....If they embrace the dark side, immunopathology 👻
Travelling the Galaxy (BM to Liver and beyond)
Innately sensing the force (Receptors & antigens on other cells)
Controlling it (IFNg secretion)
Wielding a lightsaber (cytotoxic granules)
....If they embrace the dark side, immunopathology 👻
Reposted by ImmuNoah's Ark (Noe Rodriguez)
🎃 Happy Halloween! Ever wondered what your immune cells would wear to a costume party?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
October 31, 2025 at 5:25 PM
🎃 Happy Halloween! Ever wondered what your immune cells would wear to a costume party?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
🚑 Neutrophil as an EMT: First responder on duty!
🥷 Killer T-Cell as a K-Pop Demon Hunter: Eliminating threats with precision!
What do you think each immune cell would wear for Halloween?
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Exciting day for the lab: our 1rst paper is officially out in @currentbiology.bsky.social 🥳 Wonderful collaboration wt @gautamdey.bsky.social showing how Cryo-ExM achieves consistent immunostaining in diverse diatoms, from the lab and the natural environment 1/n
#ProtistsOnSky
tinyurl.com/2zxaund7
#ProtistsOnSky
tinyurl.com/2zxaund7
October 31, 2025 at 3:27 PM
Exciting day for the lab: our 1rst paper is officially out in @currentbiology.bsky.social 🥳 Wonderful collaboration wt @gautamdey.bsky.social showing how Cryo-ExM achieves consistent immunostaining in diverse diatoms, from the lab and the natural environment 1/n
#ProtistsOnSky
tinyurl.com/2zxaund7
#ProtistsOnSky
tinyurl.com/2zxaund7
Reposted by ImmuNoah's Ark (Noe Rodriguez)
Now in #Science #Immunology: Hirahara lab reports activated #TH2 cells store LC-UFAs present in inflamed #lung within #lipid droplets. Subsequent catabolism via #microlipophagy induces ST2-hi effector & memory TH2 cell phenotypes, exacerbating #type2 #airway #inflammation!
#asthma #immunometabolism
#asthma #immunometabolism
Lipolysis-microlipophagy cascade regulated by adipose triglyceride lipase drives pathogenic adaptive type 2 immunity
Enzymatic and autophagic catabolism of lipid droplets after unsaturated fatty acid uptake induces pathogenic TH2 cells.
www.science.org
October 24, 2025 at 6:54 PM
Now in #Science #Immunology: Hirahara lab reports activated #TH2 cells store LC-UFAs present in inflamed #lung within #lipid droplets. Subsequent catabolism via #microlipophagy induces ST2-hi effector & memory TH2 cell phenotypes, exacerbating #type2 #airway #inflammation!
#asthma #immunometabolism
#asthma #immunometabolism