Helena Kilpinen
@hkilpinen.bsky.social
Associate Professor in Human Genetics and Genomic Medicine @HiLIFE_helsinki, @FIMM_UH, @UH_Neuro and Faculty of Medicine. Stem cells, single cells, genomics, and neurodevelopment.
Reposted by Helena Kilpinen
Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n
openrxiv.org/enabling-rev...
openrxiv.org/enabling-rev...
Enabling options for review: from training and transparency to author-centered AI tools - openRxiv
Peer review is widely viewed as a critical aspect of biomedical communication. Ideally, it provides authors with feedback so they can improve manuscripts and gives readers, particularly nonspecialists...
openrxiv.org
November 6, 2025 at 2:32 PM
Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n
openrxiv.org/enabling-rev...
openrxiv.org/enabling-rev...
Reposted by Helena Kilpinen
In praise of fundamental research
Our editorial this week argues that I n these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different
🧪
@nature.com
www.nature.com/articles/d41...
Our editorial this week argues that I n these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different
🧪
@nature.com
www.nature.com/articles/d41...
From MRI to Ozempic: breakthroughs that show why fundamental research must be protected
In these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different.
www.nature.com
October 30, 2025 at 1:53 PM
In praise of fundamental research
Our editorial this week argues that I n these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different
🧪
@nature.com
www.nature.com/articles/d41...
Our editorial this week argues that I n these financially straitened times, funders must recognize that great discoveries often arise from work that was looking for something completely different
🧪
@nature.com
www.nature.com/articles/d41...
Reposted by Helena Kilpinen
Beyond Transcriptomics: Can Imaging Bridge the Gap in Variant Interpretation?-join @hkilpinen.bsky.social @melinaclaussnitzer.bsky.social Alessandro Palma from @fabiantheis.bsky.social @enoutahi.bsky.social and myself at #ASHG25 for our Featured Symposium.
October 11, 2025 at 5:19 PM
Beyond Transcriptomics: Can Imaging Bridge the Gap in Variant Interpretation?-join @hkilpinen.bsky.social @melinaclaussnitzer.bsky.social Alessandro Palma from @fabiantheis.bsky.social @enoutahi.bsky.social and myself at #ASHG25 for our Featured Symposium.
Reposted by Helena Kilpinen
Larry Richardson appeared to be an early-career mathematician with potential, racking up more than 130 citations in 4 years.
It would all be rather remarkable—if the studies weren’t complete gibberish. And if Larry wasn’t a cat. #InternationalCatDay scim.ag/4lg3wTp
It would all be rather remarkable—if the studies weren’t complete gibberish. And if Larry wasn’t a cat. #InternationalCatDay scim.ag/4lg3wTp
How easy is it to fudge your scientific rank? Meet Larry, the world’s most cited cat
“Exercise in absurdity” reveals flaws in Google Scholar’s productivity metrics
scim.ag
August 8, 2025 at 5:58 PM
Larry Richardson appeared to be an early-career mathematician with potential, racking up more than 130 citations in 4 years.
It would all be rather remarkable—if the studies weren’t complete gibberish. And if Larry wasn’t a cat. #InternationalCatDay scim.ag/4lg3wTp
It would all be rather remarkable—if the studies weren’t complete gibberish. And if Larry wasn’t a cat. #InternationalCatDay scim.ag/4lg3wTp
Still time to apply for this, closes Aug 15th. Come work with us!
Job alert ‼️ @thomasdwkim.bsky.social and I are recruiting a postdoc in single-cell genomics via the NORPOD program of the @nordicembl.bsky.social. Collaboration between @fimm-uh.bsky.social and @dandrite.bsky.social on multimodal data integration in neurodevelopment.
jobs.helsinki.fi/job/Helsinki...
jobs.helsinki.fi/job/Helsinki...
Postdoctoral Researcher in Single-Cell Genomics through the NORPOD program
Postdoctoral Researcher in Single-Cell Genomics through the NORPOD program
jobs.helsinki.fi
July 31, 2025 at 11:21 AM
Still time to apply for this, closes Aug 15th. Come work with us!
Reposted by Helena Kilpinen
'Vacations.'
The word is 'vacations.'
The word is 'vacations.'
July 7, 2025 at 5:53 PM
'Vacations.'
The word is 'vacations.'
The word is 'vacations.'
Reposted by Helena Kilpinen
Exciting Research Professorship Position in Stem Cell and Developmental Biology at the University of Leuven. Amazing research ecosystem, great colleagues, high quality of life, tenure track. For those interested in joining us, please see below:
www.kuleuven.be/personeel/jo...
www.kuleuven.be/personeel/jo...
July 7, 2025 at 2:01 PM
Exciting Research Professorship Position in Stem Cell and Developmental Biology at the University of Leuven. Amazing research ecosystem, great colleagues, high quality of life, tenure track. For those interested in joining us, please see below:
www.kuleuven.be/personeel/jo...
www.kuleuven.be/personeel/jo...
Reposted by Helena Kilpinen
If you don’t have time to take a walk, then you don’t have time to do science. Charles Darwin would take two walks every day on his "thinking path", not as a break from science, but as a crucial part of it.
June 30, 2025 at 8:20 AM
If you don’t have time to take a walk, then you don’t have time to do science. Charles Darwin would take two walks every day on his "thinking path", not as a break from science, but as a crucial part of it.
Reposted by Helena Kilpinen
"The goal of academic training is not to solve problems as efficiently and quickly as possible, but to develop skills for identifying and dealing with novel problems, which have never been solved before"
<- this open letter should be read by everyone in #HigherEd
openletter.earth/open-letter-...
<- this open letter should be read by everyone in #HigherEd
openletter.earth/open-letter-...
Open Letter: Stop the Uncritical Adoption of AI Technologies in Academia
openletter.earth
June 29, 2025 at 10:19 AM
"The goal of academic training is not to solve problems as efficiently and quickly as possible, but to develop skills for identifying and dealing with novel problems, which have never been solved before"
<- this open letter should be read by everyone in #HigherEd
openletter.earth/open-letter-...
<- this open letter should be read by everyone in #HigherEd
openletter.earth/open-letter-...
Reposted by Helena Kilpinen
Wonderful tribute to a dear colleague- well worth the read www.ucsf.edu/news/2025/06...
UCSF Bioinformatics Pioneer Atul Butte Dies at 55
Atul Butte, who championed the use of big data in science and health care and inspired a generation of trainees at UC San Francisco and beyond to pursue the fields he pioneered — translational and cli...
www.ucsf.edu
June 25, 2025 at 12:51 AM
Wonderful tribute to a dear colleague- well worth the read www.ucsf.edu/news/2025/06...
Job alert ‼️ @thomasdwkim.bsky.social and I are recruiting a postdoc in single-cell genomics via the NORPOD program of the @nordicembl.bsky.social. Collaboration between @fimm-uh.bsky.social and @dandrite.bsky.social on multimodal data integration in neurodevelopment.
jobs.helsinki.fi/job/Helsinki...
jobs.helsinki.fi/job/Helsinki...
Postdoctoral Researcher in Single-Cell Genomics through the NORPOD program
Postdoctoral Researcher in Single-Cell Genomics through the NORPOD program
jobs.helsinki.fi
June 25, 2025 at 8:36 AM
Job alert ‼️ @thomasdwkim.bsky.social and I are recruiting a postdoc in single-cell genomics via the NORPOD program of the @nordicembl.bsky.social. Collaboration between @fimm-uh.bsky.social and @dandrite.bsky.social on multimodal data integration in neurodevelopment.
jobs.helsinki.fi/job/Helsinki...
jobs.helsinki.fi/job/Helsinki...
Reposted by Helena Kilpinen
📣 We are recruiting 2-3 early-stage group leaders. 📣
Join an institute where cross-disciplinary teamwork and national health-data resources let you ask the questions no one else can!
🚀 Apply here by 10 Aug to start your own research group:
jobs.helsinki.fi/job/Helsinki...
#ScienceJobs
Join an institute where cross-disciplinary teamwork and national health-data resources let you ask the questions no one else can!
🚀 Apply here by 10 Aug to start your own research group:
jobs.helsinki.fi/job/Helsinki...
#ScienceJobs
June 18, 2025 at 7:15 AM
📣 We are recruiting 2-3 early-stage group leaders. 📣
Join an institute where cross-disciplinary teamwork and national health-data resources let you ask the questions no one else can!
🚀 Apply here by 10 Aug to start your own research group:
jobs.helsinki.fi/job/Helsinki...
#ScienceJobs
Join an institute where cross-disciplinary teamwork and national health-data resources let you ask the questions no one else can!
🚀 Apply here by 10 Aug to start your own research group:
jobs.helsinki.fi/job/Helsinki...
#ScienceJobs
Reposted by Helena Kilpinen
FIMM, the Faculty of Medicine, and the Faculty of Science @helsinki.fi invite applications for
POSITIONS OF RESEARCH FELLOW (UNIVERSITY RESEARCHER) AND/OR POSTDOCTORAL RESEARCHER
at the intersection of AI, molecular medicine and health data science.
Apply by 5 June: jobs.helsinki.fi/job/Helsinki...
POSITIONS OF RESEARCH FELLOW (UNIVERSITY RESEARCHER) AND/OR POSTDOCTORAL RESEARCHER
at the intersection of AI, molecular medicine and health data science.
Apply by 5 June: jobs.helsinki.fi/job/Helsinki...
May 20, 2025 at 7:55 AM
FIMM, the Faculty of Medicine, and the Faculty of Science @helsinki.fi invite applications for
POSITIONS OF RESEARCH FELLOW (UNIVERSITY RESEARCHER) AND/OR POSTDOCTORAL RESEARCHER
at the intersection of AI, molecular medicine and health data science.
Apply by 5 June: jobs.helsinki.fi/job/Helsinki...
POSITIONS OF RESEARCH FELLOW (UNIVERSITY RESEARCHER) AND/OR POSTDOCTORAL RESEARCHER
at the intersection of AI, molecular medicine and health data science.
Apply by 5 June: jobs.helsinki.fi/job/Helsinki...
Reposted by Helena Kilpinen
Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. nyti.ms/4j49xBy
May 15, 2025 at 5:09 PM
Breaking News: A baby with a rare disorder made medical history by receiving the first custom gene-editing treatment. The technique used has the potential to help people with thousands of other uncommon genetic diseases. nyti.ms/4j49xBy
Reposted by Helena Kilpinen
FACULTY JOB ALERT! The Albert Einstein Dept of Neuroscience is hiring a new assistant professor in any area of neuroscience! We have funds specifically earmarked for this search. #Neuroscience #AcademicJobs #NeuroSky Job just posted: faculty-einstein.icims.com/jobs/17175/f... Please share widely!!
Albert Einstein College of Medicine | Medical Education | Biomedical Research
faculty-einstein.icims.com
March 26, 2025 at 5:52 PM
FACULTY JOB ALERT! The Albert Einstein Dept of Neuroscience is hiring a new assistant professor in any area of neuroscience! We have funds specifically earmarked for this search. #Neuroscience #AcademicJobs #NeuroSky Job just posted: faculty-einstein.icims.com/jobs/17175/f... Please share widely!!
Reposted by Helena Kilpinen
Scientists have just cured pancreatic cancer in some patients with personalized mRNA vaccines. Pancreatic cancer. And this Trump administration wants to throw it all away.
They’re throwing away a cure for cancer.
They’re throwing away a cure for cancer.
Exclusive: NIH officials have advised scientists to remove reference to mRNA vaccines from their grant applications, in expectation the Trump administration intends to abandon most research in the field.
By @arthurallen202.bsky.social
kffhealthnews.org/news/article...
By @arthurallen202.bsky.social
kffhealthnews.org/news/article...
Scientists Say NIH Officials Told Them To Scrub mRNA References on Grants - KFF Health News
Two senior scientists say National Institutes of Health officials advised them to remove references to mRNA vaccines in grant applications, and they fear the Trump administration will abandon a promis...
kffhealthnews.org
March 17, 2025 at 1:16 AM
Scientists have just cured pancreatic cancer in some patients with personalized mRNA vaccines. Pancreatic cancer. And this Trump administration wants to throw it all away.
They’re throwing away a cure for cancer.
They’re throwing away a cure for cancer.
Reposted by Helena Kilpinen
Yesterday, excellent science in the fully booked 2025 edition of Single Cell Omics symposium @helsinki.fi, with 300 participants! With Judith Zaugg & @mkuijjer.bsky.social,@haikalab.bsky.social, Minna Kaikkonen-Määttä, Maria Kasper, @e-manieri.bsky.social, Giole La Manno & @hagentilgner.bsky.social.
March 14, 2025 at 7:36 AM
Yesterday, excellent science in the fully booked 2025 edition of Single Cell Omics symposium @helsinki.fi, with 300 participants! With Judith Zaugg & @mkuijjer.bsky.social,@haikalab.bsky.social, Minna Kaikkonen-Määttä, Maria Kasper, @e-manieri.bsky.social, Giole La Manno & @hagentilgner.bsky.social.
This piece is spot on. While the situation in Finnish universities is perhaps not as bad yet, we are definitely on the slippery slope already.
academic.oup.com/brain/articl...
academic.oup.com/brain/articl...
On the responsibilities of intellectuals and the rise of bullshit jobs in universities
You may never have considered yourself to be one. Why would you? But if you’re reading this, there is more than a likelihood that you are one. If you’re a
academic.oup.com
March 12, 2025 at 3:57 PM
This piece is spot on. While the situation in Finnish universities is perhaps not as bad yet, we are definitely on the slippery slope already.
academic.oup.com/brain/articl...
academic.oup.com/brain/articl...
Reposted by Helena Kilpinen
If you’re at a European institution and are looking to poach American scientists, this would be a very good week to do it
January 28, 2025 at 8:31 AM
If you’re at a European institution and are looking to poach American scientists, this would be a very good week to do it
Reposted by Helena Kilpinen
How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3)
doi.org/10.1038/s415...
doi.org/10.1038/s415...
Analysis of multi-condition single-cell data with latent embedding multivariate regression - Nature Genetics
Latent embedding multivariate regression models multi-condition single-cell RNA-seq using a continuous latent space, enabling data integration, per-cell gene expression prediction and clustering-free ...
doi.org
January 3, 2025 at 7:18 PM
How to do differential expression with scRNAseq data? State of the art is "pseudo-bulk" analysis with RNA-seq methods like edgeR or DESeq2, where "cell type" is encoded as discrete categories. Biologically, discrete categories are not always the most appropriate concept.(1/3)
doi.org/10.1038/s415...
doi.org/10.1038/s415...
Reposted by Helena Kilpinen
A fun day in the lab today with some very special guests, colors, and slime-making. Downside: they now think that this is what I do every day.. #nextgeneration #bringyourkidstoworkday
November 22, 2024 at 1:04 PM
A fun day in the lab today with some very special guests, colors, and slime-making. Downside: they now think that this is what I do every day.. #nextgeneration #bringyourkidstoworkday
Reposted by Helena Kilpinen
There's a new open call for a junior faculty position at the Centre for Genomic Regulation.
The CRG is an excellent place to start your own lab!
recruitment.crg.eu/content/jobs...
The CRG is an excellent place to start your own lab!
recruitment.crg.eu/content/jobs...
October 30, 2023 at 10:01 AM
There's a new open call for a junior faculty position at the Centre for Genomic Regulation.
The CRG is an excellent place to start your own lab!
recruitment.crg.eu/content/jobs...
The CRG is an excellent place to start your own lab!
recruitment.crg.eu/content/jobs...
Reposted by Helena Kilpinen
Many people take "non-traditional" career paths in academia.
My Leading Edge colleagues and I did! We wrote for
PLOS Biology about how non-linear careers are increasingly common, but funding agencies and search committees penalize these paths. journals.plos.org/plosbiology/...
My Leading Edge colleagues and I did! We wrote for
PLOS Biology about how non-linear careers are increasingly common, but funding agencies and search committees penalize these paths. journals.plos.org/plosbiology/...
Supporting nonlinear careers to diversify science
Those who follow non-linear career trajectories often face disadvantages in academia. This Perspective looks at why individuals might choose non-linear careers and how these benefit diversity in scien...
journals.plos.org
September 14, 2023 at 7:29 PM
Many people take "non-traditional" career paths in academia.
My Leading Edge colleagues and I did! We wrote for
PLOS Biology about how non-linear careers are increasingly common, but funding agencies and search committees penalize these paths. journals.plos.org/plosbiology/...
My Leading Edge colleagues and I did! We wrote for
PLOS Biology about how non-linear careers are increasingly common, but funding agencies and search committees penalize these paths. journals.plos.org/plosbiology/...