George Bouras
@gbouras13.bsky.social
Bioinformatics @ University of Adelaide
- phages, microbes and more
- phages, microbes and more
Pinned
George Bouras
@gbouras13.bsky.social
· Aug 8
Protein Structure Informed Bacteriophage Genome Annotation with Phold
Bacteriophage (phage) genome annotation is essential for understanding their functional potential and suitability for use as therapeutic agents. Here we introduce Phold, an annotation framework utilis...
www.biorxiv.org
Stoked to finally have a preprint out for Phold, our tool that uses protein structural information to enhance phage genome annotation #phagesky 1/n
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by George Bouras
That’s a wrap! Huge thank you to everyone who joined us for #ABACBS2025 & a big shout-out to the Adelaide bioinfo community who worked their butts off. Couldn’t have asked for a better crew or a better venue than Adelaide Oval. @wessidepraxis.bsky.social @linsalrob.bsky.social
November 28, 2025 at 5:58 AM
That’s a wrap! Huge thank you to everyone who joined us for #ABACBS2025 & a big shout-out to the Adelaide bioinfo community who worked their butts off. Couldn’t have asked for a better crew or a better venue than Adelaide Oval. @wessidepraxis.bsky.social @linsalrob.bsky.social
Reposted by George Bouras
Wonderful week at ABACBS and BioCAsia conferences in Adelaide, Australia.
Thanks everyone who joined the workshop on Orchestrating Microbiome Analysis with Bioconductor, you made it awesome!
@abacbs.bsky.social
@bioconductor.bsky.social
#ABACBS2025
#BioCAsia2025
Thanks everyone who joined the workshop on Orchestrating Microbiome Analysis with Bioconductor, you made it awesome!
@abacbs.bsky.social
@bioconductor.bsky.social
#ABACBS2025
#BioCAsia2025
November 28, 2025 at 6:20 AM
Wonderful week at ABACBS and BioCAsia conferences in Adelaide, Australia.
Thanks everyone who joined the workshop on Orchestrating Microbiome Analysis with Bioconductor, you made it awesome!
@abacbs.bsky.social
@bioconductor.bsky.social
#ABACBS2025
#BioCAsia2025
Thanks everyone who joined the workshop on Orchestrating Microbiome Analysis with Bioconductor, you made it awesome!
@abacbs.bsky.social
@bioconductor.bsky.social
#ABACBS2025
#BioCAsia2025
This was one of the best workshops I have ever been to.
I came out of it with a Wasm app for making pharokka/phold/phynteny's genome maps - available at gbouras13.github.io/phold-plot-w...
It runs the browser almost instantly - please give it a go with your phages of interest!
#ABACBS2025
I came out of it with a Wasm app for making pharokka/phold/phynteny's genome maps - available at gbouras13.github.io/phold-plot-w...
It runs the browser almost instantly - please give it a go with your phages of interest!
#ABACBS2025
November 28, 2025 at 4:23 AM
This was one of the best workshops I have ever been to.
I came out of it with a Wasm app for making pharokka/phold/phynteny's genome maps - available at gbouras13.github.io/phold-plot-w...
It runs the browser almost instantly - please give it a go with your phages of interest!
#ABACBS2025
I came out of it with a Wasm app for making pharokka/phold/phynteny's genome maps - available at gbouras13.github.io/phold-plot-w...
It runs the browser almost instantly - please give it a go with your phages of interest!
#ABACBS2025
Reposted by George Bouras
Last workshop for ABACBS and BiocAsia. Really great turnout and material, led by Ning, Nora and Monika. Great way to finish a top notch week
November 28, 2025 at 3:06 AM
Last workshop for ABACBS and BiocAsia. Really great turnout and material, led by Ning, Nora and Monika. Great way to finish a top notch week
Reposted by George Bouras
This package to decompose weighted graphs into weighted paths by @alextomescu.bsky.social is going to be very useful. Can't wait to try it out in my viral metagenomic tools. 🤩🧬🖥️
#bioinformatics #graphs #graph-algorithms #flow-decomposition #integer-linear-programming
github.com/algbio/flowp...
#bioinformatics #graphs #graph-algorithms #flow-decomposition #integer-linear-programming
github.com/algbio/flowp...
GitHub - algbio/flowpaths: A Python package to quickly decompose weighted graphs (acyclic or not) into weighted paths or walks, under various models.
A Python package to quickly decompose weighted graphs (acyclic or not) into weighted paths or walks, under various models. - algbio/flowpaths
github.com
November 28, 2025 at 12:18 AM
This package to decompose weighted graphs into weighted paths by @alextomescu.bsky.social is going to be very useful. Can't wait to try it out in my viral metagenomic tools. 🤩🧬🖥️
#bioinformatics #graphs #graph-algorithms #flow-decomposition #integer-linear-programming
github.com/algbio/flowp...
#bioinformatics #graphs #graph-algorithms #flow-decomposition #integer-linear-programming
github.com/algbio/flowp...
Reposted by George Bouras
Client-side bioinformatics workshop done ✅ massive thanks to legends @lonsbio.bsky.social @lfeatherstone.bsky.social @torstenseemann.bsky.social #ABACBS2025
November 27, 2025 at 7:23 AM
Client-side bioinformatics workshop done ✅ massive thanks to legends @lonsbio.bsky.social @lfeatherstone.bsky.social @torstenseemann.bsky.social #ABACBS2025
Reposted by George Bouras
Our cornetto work is now published at www.nature.com/articles/s41...
It can do near-T2T assembly using @nanoporetech.com adaptive sampling
- with less 💸
- reference agnostic, so works for non-humans
- not just blood, even saliva
Just presented at #abacbs2025 yesterday.
It can do near-T2T assembly using @nanoporetech.com adaptive sampling
- with less 💸
- reference agnostic, so works for non-humans
- not just blood, even saliva
Just presented at #abacbs2025 yesterday.
Targeted sequencing and iterative assembly of near-complete genomes - Nature Communications
Long-read sequencing enables high-quality genome assemblies, but challenges remain. Here, the authors introduce Cornetto, a method that improves assembly quality, enables genome sequencing from saliva...
www.nature.com
November 26, 2025 at 4:12 AM
Our cornetto work is now published at www.nature.com/articles/s41...
It can do near-T2T assembly using @nanoporetech.com adaptive sampling
- with less 💸
- reference agnostic, so works for non-humans
- not just blood, even saliva
Just presented at #abacbs2025 yesterday.
It can do near-T2T assembly using @nanoporetech.com adaptive sampling
- with less 💸
- reference agnostic, so works for non-humans
- not just blood, even saliva
Just presented at #abacbs2025 yesterday.
Workshops underway this morning! #ABACBS2025
November 26, 2025 at 10:58 PM
Workshops underway this morning! #ABACBS2025
Reposted by George Bouras
And also a fantastic keynote at #ABACBS2025 on this story!
Long read Metagenomics, #phage and #prophage in the gut by Ami Bhatt's group. Beautiful data showing changes in phages over two years
#phagesky
www.nature.com/articles/s41...
#phagesky
www.nature.com/articles/s41...
Long-read metagenomics reveals phage dynamics in the human gut microbiome - Nature
Complex prophage integration dynamics, including low-level induction, cross-family host range and transposase-mediated mobilization, challenge existing paradigms and deepen our understanding of phage–...
www.nature.com
November 26, 2025 at 9:56 PM
And also a fantastic keynote at #ABACBS2025 on this story!
Reposted by George Bouras
LoL-align: sensitive and fast probabilistic protein structure alignment https://www.biorxiv.org/content/10.1101/2025.11.24.690091v1
November 26, 2025 at 2:46 AM
LoL-align: sensitive and fast probabilistic protein structure alignment https://www.biorxiv.org/content/10.1101/2025.11.24.690091v1
Reposted by George Bouras
@acepigenetics.bsky.social team at #ABACBS2025! Grateful for the chance to help plan and organise this year’s meeting and to chair the single cell and spatial session, where my colleague and dear friend Ning is our invited speaker. Biggest congrats to @mmohenska.bsky.social for her poster award!
November 26, 2025 at 9:54 AM
@acepigenetics.bsky.social team at #ABACBS2025! Grateful for the chance to help plan and organise this year’s meeting and to chair the single cell and spatial session, where my colleague and dear friend Ning is our invited speaker. Biggest congrats to @mmohenska.bsky.social for her poster award!
Reposted by George Bouras
Thanks to the amazing Adelaide Bioinformatics community for making #ABACBS2025 an amazing event. We couldn’t have done it without you. A few more days of workshops to go before the festival finishes for another year 😀
November 26, 2025 at 10:02 AM
Thanks to the amazing Adelaide Bioinformatics community for making #ABACBS2025 an amazing event. We couldn’t have done it without you. A few more days of workshops to go before the festival finishes for another year 😀
Reposted by George Bouras
10 years ago I took a flight to Sydney to attend my first COMBINE. The support of @shazanfar.bsky.social @hdashnow.bsky.social and @lonsbio.bsky.social meant the world and I made so many friends that year I still get to hang out with.Thanks to everyone for a successful conference! #ABACBS2025
November 26, 2025 at 5:56 AM
10 years ago I took a flight to Sydney to attend my first COMBINE. The support of @shazanfar.bsky.social @hdashnow.bsky.social and @lonsbio.bsky.social meant the world and I made so many friends that year I still get to hang out with.Thanks to everyone for a successful conference! #ABACBS2025
What an amazing talk by Beth Cross as the winner of the best talk at COMBINE about the genomic jigsaw of blakpc transposons - and maybe it’s time for someone to develop a better (bacterial) promoter prediction tool #ABACBS2025
November 26, 2025 at 5:54 AM
What an amazing talk by Beth Cross as the winner of the best talk at COMBINE about the genomic jigsaw of blakpc transposons - and maybe it’s time for someone to develop a better (bacterial) promoter prediction tool #ABACBS2025
Reposted by George Bouras
Reposted by George Bouras
Thrilled to get to hear Bethany Cross’ talk for a second time, such a well deserved best COMBINE talk!
#ABACBS2025
⚫️🔴
🔵⚪️
#ABACBS2025
⚫️🔴
🔵⚪️
November 26, 2025 at 5:24 AM
Thrilled to get to hear Bethany Cross’ talk for a second time, such a well deserved best COMBINE talk!
#ABACBS2025
⚫️🔴
🔵⚪️
#ABACBS2025
⚫️🔴
🔵⚪️
Reposted by George Bouras
Congratulations Hiruna Samarakoon (yet to be on bluesky) for winning the #abacbs2025 “Torsten Seemann” Outstanding Bioinformatics Software Developer Award!!! 🎉🎉🎉
November 26, 2025 at 5:01 AM
Congratulations Hiruna Samarakoon (yet to be on bluesky) for winning the #abacbs2025 “Torsten Seemann” Outstanding Bioinformatics Software Developer Award!!! 🎉🎉🎉
Reposted by George Bouras
Such a cool and interesting talk by Dr Sally Lau @lausally.bsky.social on Octopus DNA and the collapse of Ice sheets in Antarctic!
#Confbingo update - presentation on dangerous animals ✅✅ #ABACBS2025
#Confbingo update - presentation on dangerous animals ✅✅ #ABACBS2025
November 26, 2025 at 4:04 AM
Such a cool and interesting talk by Dr Sally Lau @lausally.bsky.social on Octopus DNA and the collapse of Ice sheets in Antarctic!
#Confbingo update - presentation on dangerous animals ✅✅ #ABACBS2025
#Confbingo update - presentation on dangerous animals ✅✅ #ABACBS2025
Reposted by George Bouras
iplotx by Fabio Zanini supports visualising any network or tree analysis library. Can’t wait to visualise assembly graphs with iplotx! 🤩💻 #ABACBS2025 @abacbs.bsky.social
November 26, 2025 at 1:09 AM
iplotx by Fabio Zanini supports visualising any network or tree analysis library. Can’t wait to visualise assembly graphs with iplotx! 🤩💻 #ABACBS2025 @abacbs.bsky.social
Reposted by George Bouras
Ashlee Thomson taking us ALL on a ride Aboard the Pan-Genome Express at #abacbs2025 to Enhance Alignment
Precision and Variant Calling in Acute Lymphoblastic Leukaemia
Patients
Precision and Variant Calling in Acute Lymphoblastic Leukaemia
Patients
a train with the number 705 on the front of it
ALT: a train with the number 705 on the front of it
media.tenor.com
November 26, 2025 at 1:53 AM
Ashlee Thomson taking us ALL on a ride Aboard the Pan-Genome Express at #abacbs2025 to Enhance Alignment
Precision and Variant Calling in Acute Lymphoblastic Leukaemia
Patients
Precision and Variant Calling in Acute Lymphoblastic Leukaemia
Patients
Reposted by George Bouras
@hsiaochi.bsky.social talking us through how to remove unwanted variation from single cell multi-omics data with EXTruvIIInb #ABACBS2025 @abacbs.bsky.social
November 26, 2025 at 1:37 AM
@hsiaochi.bsky.social talking us through how to remove unwanted variation from single cell multi-omics data with EXTruvIIInb #ABACBS2025 @abacbs.bsky.social
Reposted by George Bouras
Loved hearing Dr. Ryan Wick’s talk on genome assemblies with Autocycler. Really amazing hearing from him as I use a lot of his tools in my every day work!
#ABACBS2025
⚫️🔴
🔵⚪️
#ABACBS2025
⚫️🔴
🔵⚪️
November 26, 2025 at 12:53 AM
Loved hearing Dr. Ryan Wick’s talk on genome assemblies with Autocycler. Really amazing hearing from him as I use a lot of his tools in my every day work!
#ABACBS2025
⚫️🔴
🔵⚪️
#ABACBS2025
⚫️🔴
🔵⚪️
Reposted by George Bouras
With Slorado, now you have more choices for GPUs when basecalling @nanoporetech.com sequencing data. This is a work we collaborated on with AMD, led by
PhD candidate @bonson-wong.bsky.social (poster at #abacbs2025) and great to see being highlighted in the AMD blog: www.amd.com/en/blogs/202...
PhD candidate @bonson-wong.bsky.social (poster at #abacbs2025) and great to see being highlighted in the AMD blog: www.amd.com/en/blogs/202...
www.amd.com
November 26, 2025 at 1:43 AM
With Slorado, now you have more choices for GPUs when basecalling @nanoporetech.com sequencing data. This is a work we collaborated on with AMD, led by
PhD candidate @bonson-wong.bsky.social (poster at #abacbs2025) and great to see being highlighted in the AMD blog: www.amd.com/en/blogs/202...
PhD candidate @bonson-wong.bsky.social (poster at #abacbs2025) and great to see being highlighted in the AMD blog: www.amd.com/en/blogs/202...
Reposted by George Bouras
You can check out the agtools preprint on bioRxiv for more details and analysis.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
agtools: a software framework to manipulate assembly graphs
Summary Assembly graphs are a fundamental data structure used by genome and metagenome assemblers to represent sequences and their overlap information, facilitating the assembler to construct longer g...
doi.org
November 26, 2025 at 1:31 AM
You can check out the agtools preprint on bioRxiv for more details and analysis.
doi.org/10.1101/2025...
doi.org/10.1101/2025...
Tom Litfin on LMIBoltz -optimising VRAM in the AF3-like model Boltz2 in modelling huge complexes - saving us from getting a bigger GPU! #ABACBS2025
November 26, 2025 at 1:30 AM
Tom Litfin on LMIBoltz -optimising VRAM in the AF3-like model Boltz2 in modelling huge complexes - saving us from getting a bigger GPU! #ABACBS2025