Clara Mutschler
@claramutschler.bsky.social
Postdoc @CUAnschutz • PhD @Cambridge_Uni • obsessed with how neurons and glia communicate 🔬🧠
Reposted by Clara Mutschler
Extremely happy to share our manuscript jointly authored by me and the amazing Lyndsay Osso! An awesome collaboration between the @ethanhugheslab.bsky.social , Dan Denman and Autobahn Therapeutics. www.nature.com/articles/s41...
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https://www.nature.com/articles/s41467-025-56092-6🧵
January 18, 2025 at 9:46 PM
Extremely happy to share our manuscript jointly authored by me and the amazing Lyndsay Osso! An awesome collaboration between the @ethanhugheslab.bsky.social , Dan Denman and Autobahn Therapeutics. www.nature.com/articles/s41...
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🧵
Reposted by Clara Mutschler
How I feel in lab meetings
November 22, 2024 at 6:46 PM
How I feel in lab meetings
Reposted by Clara Mutschler
some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
November 17, 2024 at 8:35 PM
some great starter packs for the #glia, #astrocyte, #oligodendrocyte, #microglia, #neuro researcher: gliasky, astrocytesky, microglia
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
But if you also like interactions between celltypes, please help this starter pack get started. Maybe someone can connect all of us in a feed?
go.bsky.app/MHtJzeC
Reposted by Clara Mutschler
This just out from grad student Samantha Bromley-Coolidge with help from Regis University undergrad Diego Iruegas. By the way, Regis has an awesome neuroscience program. If one of their students applies to your grad program, give them a close look!
authors.elsevier.com/a/1k7nr14Yy4...
authors.elsevier.com/a/1k7nr14Yy4...
authors.elsevier.com
November 20, 2024 at 1:35 PM
This just out from grad student Samantha Bromley-Coolidge with help from Regis University undergrad Diego Iruegas. By the way, Regis has an awesome neuroscience program. If one of their students applies to your grad program, give them a close look!
authors.elsevier.com/a/1k7nr14Yy4...
authors.elsevier.com/a/1k7nr14Yy4...
Reposted by Clara Mutschler
By popular demand: the Axon Degeneration starter pack. Definitely incomplete so let me know who I missed.
go.bsky.app/5BH6mBE
go.bsky.app/5BH6mBE
Axon degeneration
Join the conversation
go.bsky.app
November 19, 2024 at 7:36 AM
By popular demand: the Axon Degeneration starter pack. Definitely incomplete so let me know who I missed.
go.bsky.app/5BH6mBE
go.bsky.app/5BH6mBE
Reposted by Clara Mutschler
Didn't see one for Neuroscience yet; allow me to oblige
November 18, 2024 at 11:03 AM
Didn't see one for Neuroscience yet; allow me to oblige
Constantly teaching people about Vorführeffekt 🇩🇪
"Vorführeffekt" is a German term that I think of often
It's when you are trying to demonstrate something and it suddenly doesn't behave like it normally does
E.g. there's a glitch & when a technician looks at it, it seems fine. Or, you can normally do a thing, but can't when someone is watching
It's when you are trying to demonstrate something and it suddenly doesn't behave like it normally does
E.g. there's a glitch & when a technician looks at it, it seems fine. Or, you can normally do a thing, but can't when someone is watching
November 18, 2024 at 2:43 PM
Constantly teaching people about Vorführeffekt 🇩🇪
Reposted by Clara Mutschler
Oligodendroglia starter pack!
Missing many, please share and comment below to be added. Go team Oligo 🧠🦋!
go.bsky.app/JgL2evN
Missing many, please share and comment below to be added. Go team Oligo 🧠🦋!
go.bsky.app/JgL2evN
November 17, 2024 at 8:59 PM
Oligodendroglia starter pack!
Missing many, please share and comment below to be added. Go team Oligo 🧠🦋!
go.bsky.app/JgL2evN
Missing many, please share and comment below to be added. Go team Oligo 🧠🦋!
go.bsky.app/JgL2evN
Reposted by Clara Mutschler
New work from Yasmine Kamen shows that differentiating oligodendrocytes are filled with the zymogen procaspase-3. This provides a specific marker for new oligodendrocytes and suggests a role for this pathway in oligodendrocyte fate decisions.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 15, 2024 at 2:21 PM
New work from Yasmine Kamen shows that differentiating oligodendrocytes are filled with the zymogen procaspase-3. This provides a specific marker for new oligodendrocytes and suggests a role for this pathway in oligodendrocyte fate decisions.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Clara Mutschler
I am really enjoying the surge of people to bluesky but still kind of missing the VERY early career group of people! (Aging in academia is a funny thing) - I went ahead and made this starter pack go.bsky.app/Jq8YaQM - if you would like to be removed/added please let me know
November 14, 2024 at 8:48 AM
I am really enjoying the surge of people to bluesky but still kind of missing the VERY early career group of people! (Aging in academia is a funny thing) - I went ahead and made this starter pack go.bsky.app/Jq8YaQM - if you would like to be removed/added please let me know
Yay!! We finally have a glia starter pack 🧠 🎉
go.bsky.app/Lyzro3M
!WELCOME!
thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list.
apologies for missing many of you - please do reply to get added
and remember to repost so the newbies can find us!
!WELCOME!
thought we might need a starter pack for all those coming over from the birdhouse - here's a GliaSky list.
apologies for missing many of you - please do reply to get added
and remember to repost so the newbies can find us!
November 14, 2024 at 3:28 PM
Yay!! We finally have a glia starter pack 🧠 🎉
Reposted by Clara Mutschler
One part of our upgraded infrastructure may affect your profile.
If you see your handle now says “Invalid handle,” please reverify it by navigating to Settings > Change my handle > Type in your current handle > Verify DNS Record > Update.
(Basically, update to the same handle.)
If you see your handle now says “Invalid handle,” please reverify it by navigating to Settings > Change my handle > Type in your current handle > Verify DNS Record > Update.
(Basically, update to the same handle.)
August 18, 2023 at 9:35 PM
One part of our upgraded infrastructure may affect your profile.
If you see your handle now says “Invalid handle,” please reverify it by navigating to Settings > Change my handle > Type in your current handle > Verify DNS Record > Update.
(Basically, update to the same handle.)
If you see your handle now says “Invalid handle,” please reverify it by navigating to Settings > Change my handle > Type in your current handle > Verify DNS Record > Update.
(Basically, update to the same handle.)
Reposted by Clara Mutschler
And here’s the rest! A list of ECRs in the #zebrafish community 😎 Reach out if you think you should be added 🙏 🧪 go.bsky.app/HwxuHey
November 12, 2024 at 7:18 AM
And here’s the rest! A list of ECRs in the #zebrafish community 😎 Reach out if you think you should be added 🙏 🧪 go.bsky.app/HwxuHey
Reposted by Clara Mutschler
Came to check in on the hype and tbh i need to start seeing more shitposting to take this place seriously
November 12, 2024 at 2:46 AM
Came to check in on the hype and tbh i need to start seeing more shitposting to take this place seriously
Me going back to lab after submitting my thesis🫣
I put so many things off for October that I am shocked to find it is now October!
October 3, 2023 at 7:42 PM
Me going back to lab after submitting my thesis🫣
My image made it onto the cover!! 🔬 #neuroskyence #academicsky #phdsky
October 3, 2023 at 4:40 PM
My image made it onto the cover!! 🔬 #neuroskyence #academicsky #phdsky
Reposted by Clara Mutschler
"However journal-level metrics fail to identify up to 90% of the equally well-cited papers in the biomedical research literature, controlling for field and year of publication"
You do not receive enough recognition for your influential science
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
September 30, 2023 at 8:07 AM
"However journal-level metrics fail to identify up to 90% of the equally well-cited papers in the biomedical research literature, controlling for field and year of publication"
Reposted by Clara Mutschler
Did you know? Zebrafish are more closely related to fish than to zebras. #ZebrafishFunFacts 🧪
September 30, 2023 at 12:39 PM
Did you know? Zebrafish are more closely related to fish than to zebras. #ZebrafishFunFacts 🧪
Check out our new paper on mouse myelinating Schwann cell dorsal root ganglion neuron cocultures! #neuroskyence #PhDSky #AcademicSky (one day I shall remember these hashtags in the first place but apparently today is not that day😅)
Really excited to share our new paper!! We describe a detailed protocol for setting up dissociated mouse myelinating Schwann cell dorsal root ganglion neuron cocultures in microfluidic chambers, and use this model to investigate axon degeneration. journals.biologists.com/jcs/article/...
Schwann cells are axo-protective after injury irrespective of myelination status in mouse Schwann ce...
Highlighted Article: A novel method for compartmentalised mouse myelinating Schwann cell–DRG neuron cocultures, showing that Schwann cell myelination status does not influence their axon protective ...
journals.biologists.com
September 26, 2023 at 11:22 AM
Check out our new paper on mouse myelinating Schwann cell dorsal root ganglion neuron cocultures! #neuroskyence #PhDSky #AcademicSky (one day I shall remember these hashtags in the first place but apparently today is not that day😅)
Really excited to share our new paper!! We describe a detailed protocol for setting up dissociated mouse myelinating Schwann cell dorsal root ganglion neuron cocultures in microfluidic chambers, and use this model to investigate axon degeneration. journals.biologists.com/jcs/article/...
Schwann cells are axo-protective after injury irrespective of myelination status in mouse Schwann ce...
Highlighted Article: A novel method for compartmentalised mouse myelinating Schwann cell–DRG neuron cocultures, showing that Schwann cell myelination status does not influence their axon protective ...
journals.biologists.com
September 26, 2023 at 11:13 AM
Really excited to share our new paper!! We describe a detailed protocol for setting up dissociated mouse myelinating Schwann cell dorsal root ganglion neuron cocultures in microfluidic chambers, and use this model to investigate axon degeneration. journals.biologists.com/jcs/article/...
Reposted by Clara Mutschler
Mark(@sanbomics.bsky.social) put together a really nice video & walkthrough on using alevin-fry/simpleAF to process your single-cell RNA-seq data. If you're doing processing of such data, I recommend checking it out as a transparent & open alternative to CellRanger (& way faster) t.co/Hu9ueRduQ9! 🖥️🧬
Processing single-cell RNAseq counts with simpleaf (alevin-fry)
Simpleaf is a faster and more efficient alternative to other counters, such as cellranger, and it works with other single-cell chemistries. It is a wrapper f...
t.co
September 15, 2023 at 1:16 PM
Mark(@sanbomics.bsky.social) put together a really nice video & walkthrough on using alevin-fry/simpleAF to process your single-cell RNA-seq data. If you're doing processing of such data, I recommend checking it out as a transparent & open alternative to CellRanger (& way faster) t.co/Hu9ueRduQ9! 🖥️🧬
Post PhD thesis submission project: finding a new beautiful location to read all the fun books I haven’t had time to read over the past few months every single day☀️ #PhDSky #AcademicSky #neuroskyence
September 10, 2023 at 4:32 PM
Post PhD thesis submission project: finding a new beautiful location to read all the fun books I haven’t had time to read over the past few months every single day☀️ #PhDSky #AcademicSky #neuroskyence
Time to figure out if it’s worth migrating👀
September 4, 2023 at 8:45 PM
Time to figure out if it’s worth migrating👀