Mill_lab
@cilialab.bsky.social
Group at MRC HGU using genetics, cell biology and lots of imaging to unlock the mysteries of mammalian #cilia. #cilia. #centrioles #cytoskeleton #RareDisease www.cilialab.co.uk
Reposted by Mill_lab
New JCS snapshot - Asymmetries in the three-dimensional beat of Chlamydomonas reinhardtii flagella revealed by holographic microscopy
Laurence Wilson presents the key findings from their recent JCS paper with Martin Bees.
#JCSciliaSI
journals.biologists.com/jcs/article/...
Laurence Wilson presents the key findings from their recent JCS paper with Martin Bees.
#JCSciliaSI
journals.biologists.com/jcs/article/...
November 26, 2025 at 12:57 PM
New JCS snapshot - Asymmetries in the three-dimensional beat of Chlamydomonas reinhardtii flagella revealed by holographic microscopy
Laurence Wilson presents the key findings from their recent JCS paper with Martin Bees.
#JCSciliaSI
journals.biologists.com/jcs/article/...
Laurence Wilson presents the key findings from their recent JCS paper with Martin Bees.
#JCSciliaSI
journals.biologists.com/jcs/article/...
Our 53rd BSCB GenSoc UK Cilia Network e-symposium: JCS Special Issue on Cilia and Flagella was a smash hit! A staggering 🤩 435 participants 🤩 for outstanding and sometimes contentious takes on fantastic #cilia & #centrosome research. From 🇨🇱 Chile to 🇨🇳 China to the 🇨🇿 Czech Republic- #UKCilia2025 /1
November 25, 2025 at 7:14 PM
Our 53rd BSCB GenSoc UK Cilia Network e-symposium: JCS Special Issue on Cilia and Flagella was a smash hit! A staggering 🤩 435 participants 🤩 for outstanding and sometimes contentious takes on fantastic #cilia & #centrosome research. From 🇨🇱 Chile to 🇨🇳 China to the 🇨🇿 Czech Republic- #UKCilia2025 /1
#Cilia and #Centrosome friends- tomorrow is the big day!! 🎉 🎉
Organoids for #PCD, #CryoET of the base of motile cilia, TZ organization in #IRDs, macrophages & cystic niches in #PKD, how pro-inflammatory lipids & #adipogenesis AND cilia as signal-sending organelles shedding #EVs! 🤩 😍 Join us!!
Organoids for #PCD, #CryoET of the base of motile cilia, TZ organization in #IRDs, macrophages & cystic niches in #PKD, how pro-inflammatory lipids & #adipogenesis AND cilia as signal-sending organelles shedding #EVs! 🤩 😍 Join us!!
🎆 Join us for an unmissable finale to 2025! 🎆 We're thrilled to bring our #cilia & #centrosome community together 25/11/2025 15:00-17:45 GMT! Our 53rd @bscb-official.bsky.social @gensocuk.bsky.social @ukcilianetwork.bsky.social e-symposium schedule is live: www.eventbrite.co.uk/e/bscb-genso... /1
November 24, 2025 at 11:04 AM
#Cilia and #Centrosome friends- tomorrow is the big day!! 🎉 🎉
Organoids for #PCD, #CryoET of the base of motile cilia, TZ organization in #IRDs, macrophages & cystic niches in #PKD, how pro-inflammatory lipids & #adipogenesis AND cilia as signal-sending organelles shedding #EVs! 🤩 😍 Join us!!
Organoids for #PCD, #CryoET of the base of motile cilia, TZ organization in #IRDs, macrophages & cystic niches in #PKD, how pro-inflammatory lipids & #adipogenesis AND cilia as signal-sending organelles shedding #EVs! 🤩 😍 Join us!!
Reposted by Mill_lab
And yes, the swag bags. Attendees received MAHA-branded tote bags with:
- Packets of creatine
- Beef tallow potato chips ($79 for a 6-pack!!)
- Mouth tape
- RFK Jr's biography
- Beef protein bars
- Packets of creatine
- Beef tallow potato chips ($79 for a 6-pack!!)
- Mouth tape
- RFK Jr's biography
- Beef protein bars
November 21, 2025 at 5:01 PM
And yes, the swag bags. Attendees received MAHA-branded tote bags with:
- Packets of creatine
- Beef tallow potato chips ($79 for a 6-pack!!)
- Mouth tape
- RFK Jr's biography
- Beef protein bars
- Packets of creatine
- Beef tallow potato chips ($79 for a 6-pack!!)
- Mouth tape
- RFK Jr's biography
- Beef protein bars
Reposted by Mill_lab
16 (! What?) years ago I went to my first ABRCMS and was welcomed and encouraged to pursue my scientific dreams. I met folks that provided direct feedback on my graduate school applications and served a pivotal role in my career. I am honored return and give back again as faculty.
#ABRCMS2025
#ABRCMS2025
November 20, 2025 at 9:33 PM
16 (! What?) years ago I went to my first ABRCMS and was welcomed and encouraged to pursue my scientific dreams. I met folks that provided direct feedback on my graduate school applications and served a pivotal role in my career. I am honored return and give back again as faculty.
#ABRCMS2025
#ABRCMS2025
Reposted by Mill_lab
Updates for how to request childcare supplements for individual fellowships and institutional training grants. grants.nih.gov/grants/guide...
NOT-OD-25-165: Updated Frequently Asked Questions for Ruth L. Kirschstein National Research Service Award (NRSA) Childcare Costs
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Updated Frequently Asked Questions for Ruth L. Kirschstein National Research Service Award (NRSA) Childcare Costs NOT-O...
grants.nih.gov
November 20, 2025 at 5:14 PM
Updates for how to request childcare supplements for individual fellowships and institutional training grants. grants.nih.gov/grants/guide...
Reposted by Mill_lab
On how Vangl2 shapes the heart❤️
Planar cell polarity protein, Vangl2, goes out of its way to shape the heart through a planar polarity-independent mechanism. #preprint from the team of @meilhacsigolene.bsky.social
#preLight by @prakash-patterns.bsky.social⬇️
prelights.biologists.com/highlights/v...
Planar cell polarity protein, Vangl2, goes out of its way to shape the heart through a planar polarity-independent mechanism. #preprint from the team of @meilhacsigolene.bsky.social
#preLight by @prakash-patterns.bsky.social⬇️
prelights.biologists.com/highlights/v...
VANGL2 shapes the mouse heart tube from adjacent epithelia and without planar polarity - preLights
Planar cell polarity protein, Vangl2, goes out of its way to shape the heart through a planar polarity-independent mechanism.
prelights.biologists.com
November 20, 2025 at 12:04 PM
On how Vangl2 shapes the heart❤️
Planar cell polarity protein, Vangl2, goes out of its way to shape the heart through a planar polarity-independent mechanism. #preprint from the team of @meilhacsigolene.bsky.social
#preLight by @prakash-patterns.bsky.social⬇️
prelights.biologists.com/highlights/v...
Planar cell polarity protein, Vangl2, goes out of its way to shape the heart through a planar polarity-independent mechanism. #preprint from the team of @meilhacsigolene.bsky.social
#preLight by @prakash-patterns.bsky.social⬇️
prelights.biologists.com/highlights/v...
Reposted by Mill_lab
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
November 19, 2025 at 8:23 PM
SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT
Reposted by Mill_lab
We’re recruiting an institute director, take a look!
👇🏻
👇🏻
November 19, 2025 at 5:44 PM
We’re recruiting an institute director, take a look!
👇🏻
👇🏻
Reposted by Mill_lab
Do you want to do some frontier of knowledge research? There's still time to register for the next webinar of @hfspo.bsky.social
By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory...
www.hfsp.org/hfsp-events/...
By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory...
www.hfsp.org/hfsp-events/...
HFSP Webinar 2025: Research Grants | Human Frontier Science Program
www.hfsp.org
November 19, 2025 at 8:36 AM
Do you want to do some frontier of knowledge research? There's still time to register for the next webinar of @hfspo.bsky.social
By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory...
www.hfsp.org/hfsp-events/...
By far one of the best agencies I've worked with for my beloved HFSP project, even if it's a bumpy road...no risk no glory...
www.hfsp.org/hfsp-events/...
Reposted by Mill_lab
Key transcripts encoded centrin-like proteins, a frequent component of sensory/contractile structures in protists. We visualized tentacle ultrastructure by U-ExM with @dudinlab.bsky.social lab, discovering stunning tip and collar structures 🤯that add structural complexity to new tentacle formation.
November 18, 2025 at 4:15 PM
Key transcripts encoded centrin-like proteins, a frequent component of sensory/contractile structures in protists. We visualized tentacle ultrastructure by U-ExM with @dudinlab.bsky.social lab, discovering stunning tip and collar structures 🤯that add structural complexity to new tentacle formation.
Reposted by Mill_lab
Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526
HMS - Postdoctoral Fellow in BCMP, Brown Lab
We invite applicants for a postdoctoral fellow position in the Brown lab at Harvard Medical School in Boston, Massachusetts. The Brown lab uses structural, biophysical, and biochemical approaches to d...
academicpositions.harvard.edu
November 18, 2025 at 8:05 PM
Our lab is seeking a Postdoctoral Fellow. The position is intentionally broad, as we are looking for outstanding researchers from diverse scientific backgrounds to advance our understanding of cilia and ciliopathies: academicpositions.harvard.edu/postings/15526
Reposted by Mill_lab
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
November 18, 2025 at 10:18 AM
Are you looking for female speakers in CryoEM for seminars and conferences? Are you a woman in CryoEM and not yet on the ‚woman in CryoEM‘ list? Find your speakers and add/update name and affiliation! docs.google.com/spreadsheets...
Reposted by Mill_lab
To hear more about Rudolfo’s research, published in #JCSciliaSI, join us at the 53rd BSCB GenSoc UK Cilia and Centrosome Network e-symposium.
www.eventbrite.co.uk/e/bscb-genso...
www.eventbrite.co.uk/e/bscb-genso...
BSCB GenSoc UK Cilia and Centrosome Network e-Symposia Series
BSCB GenSoc UK Cilia and Centrosome Network e-Symposia Series
www.eventbrite.co.uk
November 17, 2025 at 3:06 PM
To hear more about Rudolfo’s research, published in #JCSciliaSI, join us at the 53rd BSCB GenSoc UK Cilia and Centrosome Network e-symposium.
www.eventbrite.co.uk/e/bscb-genso...
www.eventbrite.co.uk/e/bscb-genso...
Reposted by Mill_lab
New JCS snapshot - Renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease
Rudolfo Karl presents the key findings from their recent JCS paper with Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social & team.
#JCSciliaSI
youtu.be/RDr146QtTx4
Rudolfo Karl presents the key findings from their recent JCS paper with Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social & team.
#JCSciliaSI
youtu.be/RDr146QtTx4
JCS snapshot - Renal tissue-resident macrophages promote cystogenesis in polycystic kidney disease
YouTube video by The Company of Biologists
youtu.be
November 17, 2025 at 3:06 PM
New JCS snapshot - Renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease
Rudolfo Karl presents the key findings from their recent JCS paper with Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social & team.
#JCSciliaSI
youtu.be/RDr146QtTx4
Rudolfo Karl presents the key findings from their recent JCS paper with Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social & team.
#JCSciliaSI
youtu.be/RDr146QtTx4
Reposted by Mill_lab
I guess it never gets old...bc we love #CellMigration
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
November 14, 2025 at 8:38 PM
I guess it never gets old...bc we love #CellMigration
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
ATP has many roles: energy currency, hydrotrope, and *danger signal*
Immune cells are faster after ATP exposure, F-actin (cyan) goes to the rear for nitro boost!
www.science.org/doi/full/10....
@focalplane.bsky.social #fluorescencefriday 🧪🔬
Reposted by Mill_lab
Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
An enzymatic cascade enables sensitive and specific proximity labeling proteomics in challenging biological systems - Nature Communications
Proximity labeling allows proteomic mapping of subcellular structures. Here, Sroka et al. develop in situ APEX activation (iAPEX) to overcome limitations of labeling specificity and H2O2 toxicity, app...
www.nature.com
November 14, 2025 at 8:07 PM
Thrilled to share "in situ APEX activation" (iAPEX), a proximity labeling technology for subcellular #proteomics applied to primary #cilia. iAPEX uses an enzymatic cascade, in which a D-amino acid oxidase locally produces H2O2 to activate ascorbate peroxidase.
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Mill_lab
Rudolfo Karl, Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social and colleagues discover that renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
November 14, 2025 at 2:14 PM
Rudolfo Karl, Elvira Mass, Dagmar Wachten @wachtenlab.bsky.social and colleagues discover that renal tissue-resident macrophages promote cystogenesis in early polycystic kidney disease.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
Just heading home from our @mrcmousenetwork.bsky.social MRC NMGN Science Meeting 2025 in York where our Congenital Anomalies Cluster shared updates on our clinical VUS & phenotyping pipelines at the podium! Great discussions! #FunctionalGenomics #RareDisease #CongenitalAnomalies
November 14, 2025 at 6:40 PM
Just heading home from our @mrcmousenetwork.bsky.social MRC NMGN Science Meeting 2025 in York where our Congenital Anomalies Cluster shared updates on our clinical VUS & phenotyping pipelines at the podium! Great discussions! #FunctionalGenomics #RareDisease #CongenitalAnomalies
Reposted by Mill_lab
Correct guidance link: grants.nih.gov/grants/guide...
NOT-OD-26-005: Interim Guidance on Reopening of NIH Extramural Activities
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Interim Guidance on Reopening of NIH Extramural Activities NOT-OD-26-005. NIH
grants.nih.gov
November 14, 2025 at 5:24 PM
Correct guidance link: grants.nih.gov/grants/guide...
Reposted by Mill_lab
Updated guidance about study sections and due dates during the shut down. (Given the number of emails about issues with submission/letters of rec I had, this will help with those). grants.nih.gov/grants/guide...
NOT-OD-26-004: Information for the NIH Extramural Community During the Lapse of Federal Government Funding
NIH Funding Opportunities and Notices in the NIH Guide for Grants and Contracts: Information for the NIH Extramural Community During the Lapse of Federal Government Funding NOT-OD-26-004. NIH
grants.nih.gov
November 14, 2025 at 5:16 PM
Updated guidance about study sections and due dates during the shut down. (Given the number of emails about issues with submission/letters of rec I had, this will help with those). grants.nih.gov/grants/guide...
Reposted by Mill_lab
While trying to steer clear of the ‘best organelle’ debate, we’re delighted to highlight #JCSciliaSI, guest edited by @cilialab.bsky.social & @lottepedersen.bsky.social.
And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!
And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!
JCS Special Issue - 'Cilia and Flagella: from Basic Biology to Disease' - FocalPlane
JCS Special Issue - 'Cilia and Flagella: from Basic Biology to Disease' - News
focalplane.biologists.com
November 13, 2025 at 11:26 AM
While trying to steer clear of the ‘best organelle’ debate, we’re delighted to highlight #JCSciliaSI, guest edited by @cilialab.bsky.social & @lottepedersen.bsky.social.
And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!
And, we hope that even the most ardent fans of other organelles can agree that cilia are certainly beautiful to image!
Reposted by Mill_lab
The Next Gen Pregnancy Initiative is now accepting applications. Up to $500,000 over 4 years to support bold research into pregnancy duration, fetal growth, and pregnancy complications. Deadline: Dec 4, 2025.
Apply now buff.ly/rNhJKMW #bwfrepro
Apply now buff.ly/rNhJKMW #bwfrepro
Next Gen Pregnancy Initiative - Burroughs Wellcome Fund
by
buff.ly
October 7, 2025 at 9:33 AM
The Next Gen Pregnancy Initiative is now accepting applications. Up to $500,000 over 4 years to support bold research into pregnancy duration, fetal growth, and pregnancy complications. Deadline: Dec 4, 2025.
Apply now buff.ly/rNhJKMW #bwfrepro
Apply now buff.ly/rNhJKMW #bwfrepro
Reposted by Mill_lab
Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n
openrxiv.org/enabling-rev...
openrxiv.org/enabling-rev...
Enabling options for review: from training and transparency to author-centered AI tools - openRxiv
Peer review is widely viewed as a critical aspect of biomedical communication. Ideally, it provides authors with feedback so they can improve manuscripts and gives readers, particularly nonspecialists...
openrxiv.org
November 6, 2025 at 2:32 PM
Excited to launch an openRxiv partnership with the scientist-run AI review service qed (@qedscience.bsky.social), the brainchild of @odedrechavi.bsky.social 1/n
openrxiv.org/enabling-rev...
openrxiv.org/enabling-rev...
Reposted by Mill_lab
Laurence Wilson and Martin Bees use high-speed 3D holographic imaging to capture the flagellar beat of single algal cells, revealing changes in the ‘handedness’ of the flagellar shapes at different points in their cycle.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...
November 6, 2025 at 9:05 AM
Laurence Wilson and Martin Bees use high-speed 3D holographic imaging to capture the flagellar beat of single algal cells, revealing changes in the ‘handedness’ of the flagellar shapes at different points in their cycle.
#JCSciliaSI
journals.biologists.com/jcs/article/...
#JCSciliaSI
journals.biologists.com/jcs/article/...