Adrian Duszkiewicz
@adrian-du.bsky.social
Spatial+systems neuroscientist | Working out how the 🧠 generates 🌐 to find its 🧭 | Incoming Lecturer (Asst Prof) at the University of Manchester | Big fan of ancient things 🏺📜
Pinned
Adrian Duszkiewicz
@adrian-du.bsky.social
· Oct 15
The postsubiculum as a head-direction cortex
The organisation of thalamocortical networks follows a conserved structure. Traditionally, these are divided into primary sensory systems that receive…
www.sciencedirect.com
Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)
Great to be back at SfN in San Diego, even though the weather gods have decided to go full 'Scottish summer' this year 🌧️
If you're here and you're into spatial navigation do check out the posters below 👇 [1/n]
If you're here and you're into spatial navigation do check out the posters below 👇 [1/n]
November 15, 2025 at 6:21 PM
Great to be back at SfN in San Diego, even though the weather gods have decided to go full 'Scottish summer' this year 🌧️
If you're here and you're into spatial navigation do check out the posters below 👇 [1/n]
If you're here and you're into spatial navigation do check out the posters below 👇 [1/n]
Having a great time at the @flatironinstitute.org CCN software workshop in San Diego! Do check out their fantastic Python packages Pynapple @pynapple.bsky.social (for general neurophys analysis) and NeMoS (for GLM) github.com/flatironinstitute/nemos - they are an absolute pleasure to work with 🤩
November 14, 2025 at 6:12 PM
Having a great time at the @flatironinstitute.org CCN software workshop in San Diego! Do check out their fantastic Python packages Pynapple @pynapple.bsky.social (for general neurophys analysis) and NeMoS (for GLM) github.com/flatironinstitute/nemos - they are an absolute pleasure to work with 🤩
Reposted by Adrian Duszkiewicz
I wrote a thing on episodic memory and systems consolidation. I hope you all enjoy it and/or find it interesting.
A neural state space for episodic memories
www.sciencedirect.com/science/arti...
#neuroskyence #psychscisky #cognition 🧪
A neural state space for episodic memories
www.sciencedirect.com/science/arti...
#neuroskyence #psychscisky #cognition 🧪
A neural state space for episodic memories
Episodic memories are highly dynamic and change in nonlinear ways over time. This dynamism is not captured by existing systems consolidation theories …
www.sciencedirect.com
November 3, 2025 at 12:56 PM
I wrote a thing on episodic memory and systems consolidation. I hope you all enjoy it and/or find it interesting.
A neural state space for episodic memories
www.sciencedirect.com/science/arti...
#neuroskyence #psychscisky #cognition 🧪
A neural state space for episodic memories
www.sciencedirect.com/science/arti...
#neuroskyence #psychscisky #cognition 🧪
Reposted by Adrian Duszkiewicz
🧠✨ Genetic Tools Atlas 3.0 is here!
The GTA now has an additional 750 datasets, including 80+ mouse whole-brain light sheet microscopy images as well as the first macaque datasets.
🔗 https://portal.brain-map.org/genetic-tools/genetic-tools-atlas
#neuroskyence
The GTA now has an additional 750 datasets, including 80+ mouse whole-brain light sheet microscopy images as well as the first macaque datasets.
🔗 https://portal.brain-map.org/genetic-tools/genetic-tools-atlas
#neuroskyence
November 2, 2025 at 3:46 PM
🧠✨ Genetic Tools Atlas 3.0 is here!
The GTA now has an additional 750 datasets, including 80+ mouse whole-brain light sheet microscopy images as well as the first macaque datasets.
🔗 https://portal.brain-map.org/genetic-tools/genetic-tools-atlas
#neuroskyence
The GTA now has an additional 750 datasets, including 80+ mouse whole-brain light sheet microscopy images as well as the first macaque datasets.
🔗 https://portal.brain-map.org/genetic-tools/genetic-tools-atlas
#neuroskyence
Reposted by Adrian Duszkiewicz
A study in Nature Neuroscience shows that the moments of failed attention we experience after sleep deprivation reflect brief ‘sleep-like’ episodes in the brain, corresponding to a brain- and body-wide event with altered brain activity, pupil size and brain fluid movement. #neuroskyence 🧪
Attentional failures after sleep deprivation are locked to joint neurovascular, pupil and cerebrospinal fluid flow dynamics - Nature Neuroscience
Yang et al. show that moments of failed attention we experience after sleep deprivation reflect brief ‘sleep-like’ episodes in the brain, corresponding to a brain- and body-wide event with altered brain activity, pupil size and brain fluid movement.
go.nature.com
November 2, 2025 at 5:23 PM
A study in Nature Neuroscience shows that the moments of failed attention we experience after sleep deprivation reflect brief ‘sleep-like’ episodes in the brain, corresponding to a brain- and body-wide event with altered brain activity, pupil size and brain fluid movement. #neuroskyence 🧪
Reposted by Adrian Duszkiewicz
New primer in Cell from Patrick Haggard & @mattlongo.bsky.social
Somatosensation and the sense of self: Current Biology www.cell.com/current-biol...
#interoception #exteroception #affect #neuroskyence
Somatosensation and the sense of self: Current Biology www.cell.com/current-biol...
#interoception #exteroception #affect #neuroskyence
Somatosensation and the sense of self
In this primer, Patrick Haggard and Matthew Longo consider how sensory signals from
receptors throughout the body are integrated to produce the sense of a coherent, continuous,
sentient body that form...
www.cell.com
October 30, 2025 at 7:57 PM
New primer in Cell from Patrick Haggard & @mattlongo.bsky.social
Somatosensation and the sense of self: Current Biology www.cell.com/current-biol...
#interoception #exteroception #affect #neuroskyence
Somatosensation and the sense of self: Current Biology www.cell.com/current-biol...
#interoception #exteroception #affect #neuroskyence
Reposted by Adrian Duszkiewicz
Dopamine ≠ reward but turns out, also not the learning molecule we thought.
If DA RPE is the emperor, this work SCREAMS it was running naked all the time.
This paper got quite some attention recently. Let's simplify it a bit.
A🧵with my toy model and notes:
#neuroskyence #compneuro #NeuroAI
If DA RPE is the emperor, this work SCREAMS it was running naked all the time.
This paper got quite some attention recently. Let's simplify it a bit.
A🧵with my toy model and notes:
#neuroskyence #compneuro #NeuroAI
October 30, 2025 at 11:36 AM
Dopamine ≠ reward but turns out, also not the learning molecule we thought.
If DA RPE is the emperor, this work SCREAMS it was running naked all the time.
This paper got quite some attention recently. Let's simplify it a bit.
A🧵with my toy model and notes:
#neuroskyence #compneuro #NeuroAI
If DA RPE is the emperor, this work SCREAMS it was running naked all the time.
This paper got quite some attention recently. Let's simplify it a bit.
A🧵with my toy model and notes:
#neuroskyence #compneuro #NeuroAI
Reposted by Adrian Duszkiewicz
My co-authors have yet to move to Bluesky, so I'm pleased to announce our latest work has just been published in @nature.com Neuroscience. Amazing work led by Junheng Li, revealing that falling asleep follows a predictable bifurcation pattern #neuroskyence #sleep
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Falling asleep follows a predictable bifurcation dynamic - Nature Neuroscience
Li et al. propose a conceptual framework to study the phenomenon of falling asleep based on electroencephalogram data. They show that a tipping point marks the brain’s nonlinear wake-to-sleep transiti...
www.nature.com
October 28, 2025 at 5:35 PM
My co-authors have yet to move to Bluesky, so I'm pleased to announce our latest work has just been published in @nature.com Neuroscience. Amazing work led by Junheng Li, revealing that falling asleep follows a predictable bifurcation pattern #neuroskyence #sleep
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Reposted by Adrian Duszkiewicz
Let’s use a good occasion to break my Bluesky shyness 😅 — a new article just came out!
This one goes back to data from the very start of my PhD, and I’m so happy to see it finally published 🧠
👉 onlinelibrary.wiley.com/doi/full/10.... 🧵1/5
This one goes back to data from the very start of my PhD, and I’m so happy to see it finally published 🧠
👉 onlinelibrary.wiley.com/doi/full/10.... 🧵1/5
October 27, 2025 at 10:32 AM
Let’s use a good occasion to break my Bluesky shyness 😅 — a new article just came out!
This one goes back to data from the very start of my PhD, and I’m so happy to see it finally published 🧠
👉 onlinelibrary.wiley.com/doi/full/10.... 🧵1/5
This one goes back to data from the very start of my PhD, and I’m so happy to see it finally published 🧠
👉 onlinelibrary.wiley.com/doi/full/10.... 🧵1/5
Reposted by Adrian Duszkiewicz
Various theoretical properties derived for gamma oscillations based on canonical E-SOM-PV microcircuit connectivity using mean-field modelling, which moves beyond classic Wilson-Cowan models in important ways
biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo
biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo
A mean-field model of neural networks with PV and SOM interneurons reveals connectivity-based mechanisms of gamma oscillations
Classic theoretical models of cortical oscillations are based on the interactions between two populations of excitatory and inhibitory neurons. Nevertheless, experimental studies and network simulatio...
biorxiv.org
October 24, 2025 at 11:02 AM
Various theoretical properties derived for gamma oscillations based on canonical E-SOM-PV microcircuit connectivity using mean-field modelling, which moves beyond classic Wilson-Cowan models in important ways
biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo
biorxiv.org/content/10.1... - w. Farzin Tahvili & Matteo Di Volo
Reposted by Adrian Duszkiewicz
New paper from the lab 🚨
Led by Ali Golbabaei, this study explores the how the composition of prefrontal cortical engrams changes with memory age:
authors.elsevier.com/a/1lzT-3BtfH...
Led by Ali Golbabaei, this study explores the how the composition of prefrontal cortical engrams changes with memory age:
authors.elsevier.com/a/1lzT-3BtfH...
authors.elsevier.com
October 22, 2025 at 6:50 PM
New paper from the lab 🚨
Led by Ali Golbabaei, this study explores the how the composition of prefrontal cortical engrams changes with memory age:
authors.elsevier.com/a/1lzT-3BtfH...
Led by Ali Golbabaei, this study explores the how the composition of prefrontal cortical engrams changes with memory age:
authors.elsevier.com/a/1lzT-3BtfH...
Reposted by Adrian Duszkiewicz
I am recruiting PhD students for 2026!😃
You want to reveal the geometric signatures of natural and artificial intelligence, and understand computations in brains and AI? 🌐🧠🤖
Apply to the UCSB Geometric Intelligence Lab ✨
This is the view you'd have from... your desk🌴
You want to reveal the geometric signatures of natural and artificial intelligence, and understand computations in brains and AI? 🌐🧠🤖
Apply to the UCSB Geometric Intelligence Lab ✨
This is the view you'd have from... your desk🌴
October 22, 2025 at 5:32 PM
I am recruiting PhD students for 2026!😃
You want to reveal the geometric signatures of natural and artificial intelligence, and understand computations in brains and AI? 🌐🧠🤖
Apply to the UCSB Geometric Intelligence Lab ✨
This is the view you'd have from... your desk🌴
You want to reveal the geometric signatures of natural and artificial intelligence, and understand computations in brains and AI? 🌐🧠🤖
Apply to the UCSB Geometric Intelligence Lab ✨
This is the view you'd have from... your desk🌴
A 🍍 spotted in the wild at @edinburgh-uni.bsky.social!
Great crash course on neuro data processing with @pynapple.bsky.social and @spikeinterface.bsky.social delivered by @matthiashennig6.bsky.social, @wulfdewolf.bsky.social and Chris Halcrow. So nice to see both libraries working so well together
Great crash course on neuro data processing with @pynapple.bsky.social and @spikeinterface.bsky.social delivered by @matthiashennig6.bsky.social, @wulfdewolf.bsky.social and Chris Halcrow. So nice to see both libraries working so well together
October 21, 2025 at 4:25 PM
A 🍍 spotted in the wild at @edinburgh-uni.bsky.social!
Great crash course on neuro data processing with @pynapple.bsky.social and @spikeinterface.bsky.social delivered by @matthiashennig6.bsky.social, @wulfdewolf.bsky.social and Chris Halcrow. So nice to see both libraries working so well together
Great crash course on neuro data processing with @pynapple.bsky.social and @spikeinterface.bsky.social delivered by @matthiashennig6.bsky.social, @wulfdewolf.bsky.social and Chris Halcrow. So nice to see both libraries working so well together
Reposted by Adrian Duszkiewicz
✨My first first-author paper is out✨
Entorhinal grid-like codes for visual space during memory formation in @natcomms.nature.com ➡️ rdcu.be/eLRm2
Big thanks to everyone @isabellacwagner.bsky.social, @tobiasstaudigl.bsky.social, @olejensen.bsky.social, @doellerlab.bsky.social, @clauslamm.bsky.social
Entorhinal grid-like codes for visual space during memory formation in @natcomms.nature.com ➡️ rdcu.be/eLRm2
Big thanks to everyone @isabellacwagner.bsky.social, @tobiasstaudigl.bsky.social, @olejensen.bsky.social, @doellerlab.bsky.social, @clauslamm.bsky.social
Entorhinal grid-like codes for visual space during memory formation
Nature Communications - Eye movements during scene viewing are tied to grid-like codes in the entorhinal cortex. Grid signals are specific to later remembered scenes, covary with activity in...
rdcu.be
October 20, 2025 at 4:42 PM
✨My first first-author paper is out✨
Entorhinal grid-like codes for visual space during memory formation in @natcomms.nature.com ➡️ rdcu.be/eLRm2
Big thanks to everyone @isabellacwagner.bsky.social, @tobiasstaudigl.bsky.social, @olejensen.bsky.social, @doellerlab.bsky.social, @clauslamm.bsky.social
Entorhinal grid-like codes for visual space during memory formation in @natcomms.nature.com ➡️ rdcu.be/eLRm2
Big thanks to everyone @isabellacwagner.bsky.social, @tobiasstaudigl.bsky.social, @olejensen.bsky.social, @doellerlab.bsky.social, @clauslamm.bsky.social
Thrilled to announce I'll be joining the Division of Neuroscience at @manchester.ac.uk as a Lecturer in Feb '26!
The DuLab will explore how the brain integrates sensory streams into internal maps 🌐 using the rodent head-direction circuit, the 'neural compass', as a starting point for the journey 🧭
The DuLab will explore how the brain integrates sensory streams into internal maps 🌐 using the rodent head-direction circuit, the 'neural compass', as a starting point for the journey 🧭
October 20, 2025 at 8:20 PM
Thrilled to announce I'll be joining the Division of Neuroscience at @manchester.ac.uk as a Lecturer in Feb '26!
The DuLab will explore how the brain integrates sensory streams into internal maps 🌐 using the rodent head-direction circuit, the 'neural compass', as a starting point for the journey 🧭
The DuLab will explore how the brain integrates sensory streams into internal maps 🌐 using the rodent head-direction circuit, the 'neural compass', as a starting point for the journey 🧭
Super interesting study characterizing functional sub-modules within the tiny thalamic relay of the head-direction signal 🔥
*New preprint from the lab* – “Granularity of thalamic head direction cells”
doi.org/10.1101/2025...
🧠📈 🧪
1/11
doi.org/10.1101/2025...
🧠📈 🧪
1/11
Granularity of thalamic head direction cells
Head direction signaling is fundamental for spatial orientation and navigation. The anterodorsal nucleus of the thalamus (ADn) contains a high density of head direction (HD) cells that process sensori...
doi.org
October 20, 2025 at 4:21 AM
Super interesting study characterizing functional sub-modules within the tiny thalamic relay of the head-direction signal 🔥
Cool job opportunity in a fantastic lab!!!
Junior Researcher position (16 months) available on fMRI analysis in my lab! Apply www.genzellab.com/we-are-hiring
We are hiring! — Semantic memory Lab
www.genzellab.com
October 19, 2025 at 3:44 PM
Cool job opportunity in a fantastic lab!!!
Reposted by Adrian Duszkiewicz
The work with bats on barren, 7-acre Latham Island was Nachum Ulanovsky’s most complex undertaking yet.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
October 16, 2025 at 6:15 PM
The work with bats on barren, 7-acre Latham Island was Nachum Ulanovsky’s most complex undertaking yet.
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
By @claudia-lopez.bsky.social
#neuroskyence
www.thetransmitter.org/neuroetholog...
Reposted by Adrian Duszkiewicz
Delighted that our main #TeamReuniens paper is finally out in @plosbiology.org. Been a long time in the making, congratulations to Lilya and all the team. A thread to follow soon, after I've had some sleep... #NeuroSkyence
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Hippocampal pyramidal cells of the CA1 region are not a major target of the thalamic nucleus reuniens
Excitatory input from the prefrontal cortex to hippocampus pyramidal cells is commonly believed to be mediated through the thalamic nucleus reuniens brain region. This study shows in rodents that this...
journals.plos.org
October 13, 2025 at 8:45 PM
Delighted that our main #TeamReuniens paper is finally out in @plosbiology.org. Been a long time in the making, congratulations to Lilya and all the team. A thread to follow soon, after I've had some sleep... #NeuroSkyence
journals.plos.org/plosbiology/...
journals.plos.org/plosbiology/...
Reposted by Adrian Duszkiewicz
Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
October 16, 2025 at 3:00 PM
Out today at Neuron, our experiments show that frontal cortical representation of economic variables is jointly determined by spatial organization and downstream
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
connectivity of neurons, revealing a structured, multi-scale code for economic variables. www.cell.com/neuron/fullt...
Reposted by Adrian Duszkiewicz
Our new review on how the opioid system contributes to the mechanism of widely used antidepressants — and what new insights from ketamine research reveal is now out in Biochemical Pharmacology! Check it out
🔗: www.sciencedirect.com/science/arti...
🔗: www.sciencedirect.com/science/arti...
Antidepressants and the endogenous opioid system
The endogenous opioid system consists of three different G protein-coupled receptors, named mu-, delta- and kappa-opioid receptors (MOR, DOR, and KOR,…
www.sciencedirect.com
October 17, 2025 at 6:39 PM
Our new review on how the opioid system contributes to the mechanism of widely used antidepressants — and what new insights from ketamine research reveal is now out in Biochemical Pharmacology! Check it out
🔗: www.sciencedirect.com/science/arti...
🔗: www.sciencedirect.com/science/arti...
Reposted by Adrian Duszkiewicz
I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island.
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
October 16, 2025 at 6:04 PM
I am excited to share my PhD work on head-direction cells recorded in the wild, now published in @science.org, where we recorded neurons in bats flying outdoors on an island.
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
doi.org/10.1126/sci...
With @ray-neuro.bsky.social, Shir Maimon, Liora Las, Nachum Ulanovsky and many others
Head-direction cells... in a tropical paradise! Looks amazing, can't wait to dig into it
Head-direction cells as a neural compass in bats navigating outdoors on a remote oceanic island
Animals and humans rely on their navigation skills to survive. However, spatial neurons in the brain’s “navigation circuit” had not previously been studied under real-world conditions. We conducted an...
www.science.org
October 17, 2025 at 2:28 PM
Head-direction cells... in a tropical paradise! Looks amazing, can't wait to dig into it
Reposted by Adrian Duszkiewicz
We are delighted to support the 2025 @ucl-neurodomain.bsky.social NeuroAI Annual Conference.
Join experts in neuroscience, AI, machine learning, and related fields on Wednesday 5 November 2025 at @uclchildhealth.bsky.social
Details and registration: www.ucl.ac.uk/event-ticket...
Join experts in neuroscience, AI, machine learning, and related fields on Wednesday 5 November 2025 at @uclchildhealth.bsky.social
Details and registration: www.ucl.ac.uk/event-ticket...
October 17, 2025 at 1:42 PM
We are delighted to support the 2025 @ucl-neurodomain.bsky.social NeuroAI Annual Conference.
Join experts in neuroscience, AI, machine learning, and related fields on Wednesday 5 November 2025 at @uclchildhealth.bsky.social
Details and registration: www.ucl.ac.uk/event-ticket...
Join experts in neuroscience, AI, machine learning, and related fields on Wednesday 5 November 2025 at @uclchildhealth.bsky.social
Details and registration: www.ucl.ac.uk/event-ticket...
Reposted by Adrian Duszkiewicz
🚨new paper: the head-direction circuit as a model of primary thalamocortical system. Check this out 👇
kudos to @adrian-du.bsky.social for the huge amount of work put into this opinion piece, starting with the beautiful figures comparing the different thalamocortical systems 🤩
kudos to @adrian-du.bsky.social for the huge amount of work put into this opinion piece, starting with the beautiful figures comparing the different thalamocortical systems 🤩
Really excited to share this Opinion piece we've been working on with fellow head-direction cell geeks @apeyrache.bsky.social @desdemonafricker.bsky.social and (bsky-less?) Andrea Burgalossi! While head-direction cells pop up in many cortical regions, we think that one of them is quite unique (1/8)
The postsubiculum as a head-direction cortex
The organisation of thalamocortical networks follows a conserved structure. Traditionally, these are divided into primary sensory systems that receive…
www.sciencedirect.com
October 15, 2025 at 9:39 PM
🚨new paper: the head-direction circuit as a model of primary thalamocortical system. Check this out 👇
kudos to @adrian-du.bsky.social for the huge amount of work put into this opinion piece, starting with the beautiful figures comparing the different thalamocortical systems 🤩
kudos to @adrian-du.bsky.social for the huge amount of work put into this opinion piece, starting with the beautiful figures comparing the different thalamocortical systems 🤩