Prasanna Satpute-Krishnan
@pskcellbio.bsky.social
I am a cell biologist who studies protein quality control and proteostasis in the secretory pathway with emphasis on GPI-anchored proteins, p24-family of proteins, calnexin, endoplasmic reticulum, Golgi, and lysosomes.
Reposted by Prasanna Satpute-Krishnan
Just one week away until #CellBio2025!
Please plan to join us for a sUPeR speakER lineup at the #EndoplasmicReticulum Minisymposium!
Dec 10 at 9 AM
@ascbiology.bsky.social
Please plan to join us for a sUPeR speakER lineup at the #EndoplasmicReticulum Minisymposium!
Dec 10 at 9 AM
@ascbiology.bsky.social
Check out our @ascbiology.bsky.social #CellBio2025 Minisymposium on ER Homeostasis. With THIS speaker lineup, this event will be as dynamic, transformative and productive as the ER itself!
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
November 30, 2025 at 6:17 PM
Just one week away until #CellBio2025!
Please plan to join us for a sUPeR speakER lineup at the #EndoplasmicReticulum Minisymposium!
Dec 10 at 9 AM
@ascbiology.bsky.social
Please plan to join us for a sUPeR speakER lineup at the #EndoplasmicReticulum Minisymposium!
Dec 10 at 9 AM
@ascbiology.bsky.social
What a journey across the world and to the ER! Way to go, Guillaume 👏🏼👏🏼@gthibault.bsky.social
Thank you @jcellsci.bsky.social! It was so much fun chatting with Editor @seemagrewal.bsky.social about my journey, research, and advice for junior scientists.
It’s great that it reads just like our conversation flowed. I sincerely hope it resonates with trainees out there!
Read the interview 👇
It’s great that it reads just like our conversation flowed. I sincerely hope it resonates with trainees out there!
Read the interview 👇
Interview with Guillaume Thibault @gthibault.bsky.social – President of the Society for Cell Biology Singapore
We chatted about Guillaume’s route into academia, his research and his advice for junior scientists.
journals.biologists.com/jcs/article/...
We chatted about Guillaume’s route into academia, his research and his advice for junior scientists.
journals.biologists.com/jcs/article/...
November 11, 2025 at 3:19 AM
What a journey across the world and to the ER! Way to go, Guillaume 👏🏼👏🏼@gthibault.bsky.social
Check out our @ascbiology.bsky.social #CellBio2025 Minisymposium on ER Homeostasis. With THIS speaker lineup, this event will be as dynamic, transformative and productive as the ER itself!
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
November 9, 2025 at 6:04 PM
Check out our @ascbiology.bsky.social #CellBio2025 Minisymposium on ER Homeostasis. With THIS speaker lineup, this event will be as dynamic, transformative and productive as the ER itself!
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
So don’t 𝗦𝗧𝗥𝗘𝗦𝗦, 𝙩𝙧𝙖𝙣𝙨𝙡𝙤𝙘𝙖𝙩𝙚 yourselves over and join us to 𝗡𝗘𝗧𝗪𝗢𝗥𝗞 in world of the ER. (All PUNS intended.)
These are “can’t miss” events for membrane enthusiasts :)
Calling all #Membrane enthusiasts!
Our #MembraneTrafficking online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26.
The first talks are already next Thursday (Nov 6, 5pm CET) with @agatawitkowska.bsky.social and @abdourachidthiam.bsky.social !
Our #MembraneTrafficking online seminar series is back for the 2025-26 season: 8 fantastic speakers from Nov'25 to Feb'26.
The first talks are already next Thursday (Nov 6, 5pm CET) with @agatawitkowska.bsky.social and @abdourachidthiam.bsky.social !
October 27, 2025 at 10:36 PM
These are “can’t miss” events for membrane enthusiasts :)
This would be an amazing postdoc opportunity!
Attention membrane traffickers! I'm recruiting a post-doc to my lab in Dundee. We're dissecting the functions of intrinsically disordered domains of COPII coat proteins. We think they control timing of coat assembly and morphology of carriers.
www.dundee.ac.uk/work-for-us/...
www.dundee.ac.uk/work-for-us/...
Postdoctoral Research Assistant - MCDB - UOD2016
Closing date: Thursday 6 November 2025, 23:59
www.dundee.ac.uk
October 16, 2025 at 9:20 PM
This would be an amazing postdoc opportunity!
I can’t wait to read this!
New Online! Towards a unified framework for the function of endoplasmic reticulum exit sites
Towards a unified framework for the function of endoplasmic reticulum exit sites
Nature Reviews Molecular Cell Biology, Published online: 29 September 2025; doi:10.1038/s41580-025-00899-0Endoplasmic reticulum exit sites (ERES) are specialized ER subdomains that regulate the export of secreted cargo. This Roadmap explores how ERES integrate biochemical and mechanical signals to coordinate trafficking and proposes a multidisciplinary strategy to investigate their function, including in disease.
bit.ly
September 29, 2025 at 6:38 PM
I can’t wait to read this!
Reposted by Prasanna Satpute-Krishnan
📣 Deadline Extended! 📆
Abstract submissions for the WIA Symposium Webinar are now due Friday, Sept 19. Don’t miss your chance to showcase your work to the autophagy community!
👇Submit here:
forms.office.com/pages/respon...
Abstract submissions for the WIA Symposium Webinar are now due Friday, Sept 19. Don’t miss your chance to showcase your work to the autophagy community!
👇Submit here:
forms.office.com/pages/respon...
September 15, 2025 at 4:25 PM
📣 Deadline Extended! 📆
Abstract submissions for the WIA Symposium Webinar are now due Friday, Sept 19. Don’t miss your chance to showcase your work to the autophagy community!
👇Submit here:
forms.office.com/pages/respon...
Abstract submissions for the WIA Symposium Webinar are now due Friday, Sept 19. Don’t miss your chance to showcase your work to the autophagy community!
👇Submit here:
forms.office.com/pages/respon...
Reposted by Prasanna Satpute-Krishnan
Our first extraordinary biologist featured this week is Jennifer Lippincott-Schwartz, a @jcellsci.bsky.social Editor, @focalplane.bsky.social Scientific Advisory Board member and plenary speaker at the Biologists @ 100 conference. #biologists100 #100biologists
August 27, 2025 at 10:40 AM
Our first extraordinary biologist featured this week is Jennifer Lippincott-Schwartz, a @jcellsci.bsky.social Editor, @focalplane.bsky.social Scientific Advisory Board member and plenary speaker at the Biologists @ 100 conference. #biologists100 #100biologists
Reposted by Prasanna Satpute-Krishnan
Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday
www.nature.com/articles/nme...
www.nature.com/articles/nme...
August 22, 2025 at 1:17 PM
Today, I would like to honor the memory of Roger Y. Tsien, who died on August 24, 2016. His legacy lives with all who use his technologies, including calcium sensors, fluorescent proteins, the acetoxymethyl (AM) ester, & many more! #FluorescenceFriday
www.nature.com/articles/nme...
www.nature.com/articles/nme...
Reposted by Prasanna Satpute-Krishnan
Reposted by Prasanna Satpute-Krishnan
Happy to share my first publication, where we present our discovery of multi-chaperone condensates that orchestrate protein folding in the endoplasmic reticulum!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
August 11, 2025 at 3:07 PM
Happy to share my first publication, where we present our discovery of multi-chaperone condensates that orchestrate protein folding in the endoplasmic reticulum!
www.nature.com/articles/s41...
www.nature.com/articles/s41...
Congratulations @cohenlaboratory.bsky.social, @ibudin.bsky.social and all the 2025 ASCB award winners! This is a major achievement!
Meet the 2025 ASCB Award Winners—trailblazing scientists honored for research, mentoring, education, and innovation. Celebrate excellence across all career stages in cell biology. Read more: www.ascb.org/society-news...
August 7, 2025 at 12:27 PM
Congratulations @cohenlaboratory.bsky.social, @ibudin.bsky.social and all the 2025 ASCB award winners! This is a major achievement!
Reposted by Prasanna Satpute-Krishnan
We're thrilled to announce the largest private gift in our 137-year history: a $25 million unrestricted donation from MBL Whitman Scientist Mark Terasaki.
His extraordinary generosity will bolster our renowned research and education programs. 🔬
Learn more: bit.ly/452WL1m
His extraordinary generosity will bolster our renowned research and education programs. 🔬
Learn more: bit.ly/452WL1m
MBL Announces Largest Ever Gift for Its Renowned Biological Education and Research Programs | Marine Biological Laboratory
Cell Biology Researcher Mark Terasaki’s $25 Million Unrestricted Gift Will Support Operations and Infrastructure Contact: Samantha Cummis [email protected]; 973.800.4119
bit.ly
July 28, 2025 at 6:46 PM
We're thrilled to announce the largest private gift in our 137-year history: a $25 million unrestricted donation from MBL Whitman Scientist Mark Terasaki.
His extraordinary generosity will bolster our renowned research and education programs. 🔬
Learn more: bit.ly/452WL1m
His extraordinary generosity will bolster our renowned research and education programs. 🔬
Learn more: bit.ly/452WL1m
#Golgi folks, cannot miss this!
The #MembraneTrafficking online seminars are back this Thursday (June 26th, 5pm CEST). We'll hear from @jnuechel.bsky.social about how to find the right partner for a TANGO, and from Maohan Su about the organizational principles of the Golgi. @ishier.bsky.social @franbottanelli.bsky.social
MEMBRANE TRAFFICKING | Membrane Trafficking
felixcampelo.wixsite.com
June 24, 2025 at 2:02 AM
#Golgi folks, cannot miss this!
Reposted by Prasanna Satpute-Krishnan
What do you see when you stare at this grid of line segments: a series of rectangles, or a series of circles?
The way you perceive this optical illusion may tie back to the visual environment that surrounds you, a recent preprint suggests. scim.ag/4kTxbmd
The way you perceive this optical illusion may tie back to the visual environment that surrounds you, a recent preprint suggests. scim.ag/4kTxbmd
Culture literally changes how we see the world
Where city dwellers see rectangles, people who live in round huts see circles
scim.ag
June 20, 2025 at 7:07 PM
What do you see when you stare at this grid of line segments: a series of rectangles, or a series of circles?
The way you perceive this optical illusion may tie back to the visual environment that surrounds you, a recent preprint suggests. scim.ag/4kTxbmd
The way you perceive this optical illusion may tie back to the visual environment that surrounds you, a recent preprint suggests. scim.ag/4kTxbmd
Reposted by Prasanna Satpute-Krishnan
Gave a talk at my parents’ retirement community to describe how science is done, and what is at stake. There was a ton of interest, and anyone can do this. Get the word out about how science affects everyone. I’m happy to share slides with anyone who asks- just get in touch! youtu.be/BY_SFgi-Cig
Kara Marshall PHD-History of Science in America - Trilogy at Tehaleh 04/27/25
YouTube video by Steve Lawson
youtu.be
May 3, 2025 at 7:20 PM
Gave a talk at my parents’ retirement community to describe how science is done, and what is at stake. There was a ton of interest, and anyone can do this. Get the word out about how science affects everyone. I’m happy to share slides with anyone who asks- just get in touch! youtu.be/BY_SFgi-Cig
Reposted by Prasanna Satpute-Krishnan
tinyurl.com/mrce6bbb Fun to write this N&V together with Regina @hrshin.bsky.social, on the several cryoEM papers that build on her discovery of the fascinating LYCHOS protein and its role in cholesterol sensing and mTORC1 regulation!
Cholesterol finds its pocket in LYCHOS - Nature Structural & Molecular Biology
The lysosomal transmembrane protein LYCHOS enables activation of the master growth regulator mTORC1 kinase by cholesterol. Here we summarize recent structural findings that shed light on the LYCHOS ch...
tinyurl.com
April 28, 2025 at 3:42 PM
tinyurl.com/mrce6bbb Fun to write this N&V together with Regina @hrshin.bsky.social, on the several cryoEM papers that build on her discovery of the fascinating LYCHOS protein and its role in cholesterol sensing and mTORC1 regulation!
Reposted by Prasanna Satpute-Krishnan
Interested in chemical mechanisms of membrane proteins ?We have an opening for postbac fellows. Please share and repost. Thanks !
Our research focuses on understanding the chemical and cellular mechanisms of integral membrane enzymes and transition metal transporters.
bit.ly/42jWXYD.
/n
Our research focuses on understanding the chemical and cellular mechanisms of integral membrane enzymes and transition metal transporters.
bit.ly/42jWXYD.
/n
April 8, 2025 at 11:47 AM
Interested in chemical mechanisms of membrane proteins ?We have an opening for postbac fellows. Please share and repost. Thanks !
Our research focuses on understanding the chemical and cellular mechanisms of integral membrane enzymes and transition metal transporters.
bit.ly/42jWXYD.
/n
Our research focuses on understanding the chemical and cellular mechanisms of integral membrane enzymes and transition metal transporters.
bit.ly/42jWXYD.
/n
Reposted by Prasanna Satpute-Krishnan
Visiting Cambridge/Oxford/London w/ @sim0nredfern.bsky.social to connect w/ potential applicants for Nanyang Assistant Professorship (NAP) @ NTU SG. NAP offers tenure-track position w/ up to S$2.75M start-up. Join us and register at one of our recruitment events 👇
www.ntu.edu.sg/science/rese...
www.ntu.edu.sg/science/rese...
April 21, 2025 at 10:06 AM
Visiting Cambridge/Oxford/London w/ @sim0nredfern.bsky.social to connect w/ potential applicants for Nanyang Assistant Professorship (NAP) @ NTU SG. NAP offers tenure-track position w/ up to S$2.75M start-up. Join us and register at one of our recruitment events 👇
www.ntu.edu.sg/science/rese...
www.ntu.edu.sg/science/rese...
Happy Golgi Day!!
I’m celebrating in the lab!
I’m celebrating in the lab!
April 20, 2025 at 12:46 AM
Happy Golgi Day!!
I’m celebrating in the lab!
I’m celebrating in the lab!
This is a well written spotlight piece by Xin Xiang @xianglab.bsky.social highlighting a new discovery by Aquino et al in McNally lab. It describes a novel mechanism by which the kinesin-1-driven inward organelle packing pushes the spindle out towards the cortex. Interesting mechanism and biology!
Happy to share this short spotlight piece kwnsfk27.r.eu-west-1.awstrack.me/L0/https:%2F... published online by @cp-trendscellbio.bsky.social
for an interesting paper about an unexpected mechanism behind Kinesin-1-mediated meiotic spindle positioning in C. elegans @cp-cellreports.bsky.social
for an interesting paper about an unexpected mechanism behind Kinesin-1-mediated meiotic spindle positioning in C. elegans @cp-cellreports.bsky.social
kwnsfk27.r.eu-west-1.awstrack.me
April 11, 2025 at 2:44 AM
This is a well written spotlight piece by Xin Xiang @xianglab.bsky.social highlighting a new discovery by Aquino et al in McNally lab. It describes a novel mechanism by which the kinesin-1-driven inward organelle packing pushes the spindle out towards the cortex. Interesting mechanism and biology!
Exciting discovery by Aakriti Jain @aakritijain.bsky.social et al of the @robzonculab.bsky.social lab that LyLAP processively and rapidly proteolyses membrane-spanning hydrophobic domains of transmembrane proteins!
SO excited to share that a major part of the postdoctoral work in @robzonculab.bsky.social lab is now published: “Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins” www.science.org/doi/10.1126/...
Leucine aminopeptidase LyLAP enables lysosomal degradation of membrane proteins
Breakdown of every transmembrane protein trafficked to lysosomes requires proteolysis of their hydrophobic helical transmembrane domains. Combining lysosomal proteomics with functional genomic dataset...
www.science.org
March 30, 2025 at 3:25 AM
Exciting discovery by Aakriti Jain @aakritijain.bsky.social et al of the @robzonculab.bsky.social lab that LyLAP processively and rapidly proteolyses membrane-spanning hydrophobic domains of transmembrane proteins!
Reposted by Prasanna Satpute-Krishnan
Hey #scisky has anybody made the move to FBS substitutes for their research and is happy??? I soon may need a grant just to fund lab FBS 😭
March 26, 2025 at 8:55 PM
Hey #scisky has anybody made the move to FBS substitutes for their research and is happy??? I soon may need a grant just to fund lab FBS 😭
Good to know!!
PSA for NIH R35s: My R35 was administratively withdrawn this year because I broke my Future Research into “Aims” & they said this violated the “Do not submit a Specific Aims page or identify specific aims” policy.
So. Don’t use the word “Aims” in an R35 - use “Projects”. #critical
So. Don’t use the word “Aims” in an R35 - use “Projects”. #critical
March 20, 2025 at 10:33 PM
Good to know!!
Cool work by Jeppesen et al of the Dylan Burnette Lab @mag2art.bsky.social demonstrating and characterizing a whole new actor in the complex world of cells: blebbisomes.
Introducing blebbisomes! Cover art by @ento-sanchez.bsky.social! #CellBiology
Article: www.nature.com/articles/s41...
Article: www.nature.com/articles/s41...
March 15, 2025 at 3:44 PM
Cool work by Jeppesen et al of the Dylan Burnette Lab @mag2art.bsky.social demonstrating and characterizing a whole new actor in the complex world of cells: blebbisomes.