Vikram Paralkar
@paralkarlab.bsky.social
2.5K followers 780 following 520 posts
Physician-Scientist | University of Pennsylvania | Pol I, rRNA, Ribosomes, Chromatin, Transcription | Hematopoiesis and Leukemia | 🩸🔬🧪🧬 https://paralkarlab.med.upenn.edu
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paralkarlab.bsky.social
Little-known fact: Checking the status of a submitted manuscript multiple times a day does not cause it to more rapidly move along the internal journal pipeline...
paralkarlab.bsky.social
There comes a moment in your life when you realize that it's been forever since someone carded you at a bar or liquor store. That is a sad moment indeed ... 😢
paralkarlab.bsky.social
It's a strange and vexing feeling to read and score grants for an upcoming NIH study section this month. I have no idea if the study section will even take place, but I do know that I owe each applicant a careful assessment...
paralkarlab.bsky.social
How is it that Joan Steitz hasn't been awarded a Nobel?
paralkarlab.bsky.social
Can you imagine what the mitotic spindle looks like?!? I wonder if they develop somatic aneupolidies in the course of just normal development.
paralkarlab.bsky.social
Actually, if he had, perhaps his conclusion would have been that pretty much no trait shows Mendelian linkage with any other trait! 😜
paralkarlab.bsky.social
227 autosomes! 😱💀 One can only be grateful that Thomas Hunt Morgan didn't use the Atlas blue butterfly as his model organism...
currentbiology.bsky.social
Which journal would publish such a fragmented mess?
www.cell.com/current-biol...
Reposted by Vikram Paralkar
genesdev.bsky.social
📽️ G&D Tapes 📽️

G&D Author, Aishwarya Pawar, tells us about their new study showing that PHF6 and PHIP function together to suppress stemness programs and leukemia progression.
@aishwarya2510.bsky.social
@paralkarlab.bsky.social

Learn more here:
➡️ genesdev.cshlp.org/content/39/1...
Reposted by Vikram Paralkar
genesdev.bsky.social
RESEARCH PAPER: Leukemia mutated proteins PHF6 and PHIP form a chromatin complex that represses acute myeloid leukemia stemness
By Pawar et al. and Vikram Paralkar
Aishwarya Pawar
Vikram Paralkar

Learn more here:
 ➡️ https:
//genesdev.cshlp.org/content/39/19-20/1219.abstract
paralkarlab.bsky.social
What an incredible and impactful life!
phillewis.bsky.social
Jane Goodall, ethologist and conservationist, has died. She was 91
Reposted by Vikram Paralkar
Reposted by Vikram Paralkar
aphillippy.bsky.social
🚂 The T2T train keeps rolling: "The formation and propagation of human Robertsonian chromosomes" with Gerton and Garrison labs is out! What's a Robertsonian chromosome? Let Jen tell you herself in this great video, or read our paper: [1/3]
📺 youtu.be/JmlY5omxQVc
📄 www.nature.com/articles/s41...
How Stowers Scientists Found the DNA Site Where Robertsonian Chromosomes Fuse
YouTube video by Stowers Institute for Medical Research
youtu.be
paralkarlab.bsky.social
WAIT there's actually a bacterial culture medium called TERRIFIC BROTH?!? I thought it was just a joke that members in my lab were making... 😵‍💫
Reposted by Vikram Paralkar
Reposted by Vikram Paralkar
harmitmalik.bsky.social
Any academic folks on H1B visas (even with stamps in passports) please get legal advice from your University attorneys before leaving the US.
Reposted by Vikram Paralkar
chrislhayes.bsky.social
Not really an overstatement to say that the test of a free society is whether or not comedians can make fun of the country's leader on TV without repurcussions.
Reposted by Vikram Paralkar
teiflab.bsky.social
A random bit of history (for modern analogies). Lysenko set back genetics in USSR by ~50 years. Hundreds of geneticists imprisoned or died. Cybernetics was also named "reactionary pseudoscience", and about to undergo similar fate, but got lucky that this started close to the end of the Stalin era.
Reposted by Vikram Paralkar
vangalenlab.bsky.social
Excited to share our latest work on blood aging! To find out why the blood system changes as people age, we started at the source: hematopoietic stem cells (HSCs) #hemesky 🩸🧬 doi.org/10.1101/2025... 🧵 1/5
paralkarlab.bsky.social
Beautiful cover design!
Reposted by Vikram Paralkar
norock.bsky.social
Actually, Frankenstein is a doctor success at the Venice film festival
BBC News headline: Frankenstein is monster success at Venice film festival