Vikram Paralkar
@paralkarlab.bsky.social
Physician-Scientist | University of Pennsylvania | Pol I, rRNA, Ribosomes, Chromatin, Transcription | Hematopoiesis and Leukemia | π©Έπ¬π§ͺπ§¬
https://paralkarlab.med.upenn.edu
https://paralkarlab.med.upenn.edu
Pinned
Vikram Paralkar
@paralkarlab.bsky.social
Β· Aug 2
Dynamics of Ribosomal RNA Transcription and Abundance in Normal and Leukemic Hematopoiesis
Transcription of ribosomal RNAs (rRNAs) from rDNA repeats is the first step of ribosome biogenesis, accounting for a major portion of all cellular transcription. Often regarded as a housekeeping proce...
www.biorxiv.org
π£ New preprint π£
We present a detailed map of nascent and mature ribosomal RNAs in mouse hematopoiesis and AML (including absolute rRNA molecule numbers), and outline principles of rDNA regulation.
Work by Eleanor Sams (@eleanor44.bsky.social) & Victoria Feist (@victoriafeist.bsky.social). (1/x)
We present a detailed map of nascent and mature ribosomal RNAs in mouse hematopoiesis and AML (including absolute rRNA molecule numbers), and outline principles of rDNA regulation.
Work by Eleanor Sams (@eleanor44.bsky.social) & Victoria Feist (@victoriafeist.bsky.social). (1/x)
Me at the "Journal of Advances in Agronomy and Crop Science"
a man in a suit and tie stands in a room
ALT: a man in a suit and tie stands in a room
media.tenor.com
February 4, 2026 at 12:15 AM
Me at the "Journal of Advances in Agronomy and Crop Science"
Totally in line with my expertise and not spam at all!
February 4, 2026 at 12:11 AM
Totally in line with my expertise and not spam at all!
Reposted by Vikram Paralkar
Dr. Pavan spent decades studying rare diseases at NIH. Today, heβs battling one: first diagnosed with MDS-RARSt and, later, myelofibrosis. A stem cell transplant from his son saved his life, made possible in part by NIH-funded research. Learn more: https://ow.ly/XaWp50XXqtu
#Fight4Hematology
#Fight4Hematology
January 29, 2026 at 3:00 PM
Dr. Pavan spent decades studying rare diseases at NIH. Today, heβs battling one: first diagnosed with MDS-RARSt and, later, myelofibrosis. A stem cell transplant from his son saved his life, made possible in part by NIH-funded research. Learn more: https://ow.ly/XaWp50XXqtu
#Fight4Hematology
#Fight4Hematology
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February 2, 2026 at 6:28 PM
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Reposted by Vikram Paralkar
This just in. So honored and grateful...
We're proud to join the Vilcek Foundation in recognizing HHMI Investigator Karolin Luger, whose dedication & groundbreaking nucleosome research has led to the development of innovative new drug treatments, including cancer medicines. hhmi.news/49VciEd @vilcekfoundation.bsky.social
February 2, 2026 at 6:24 PM
This just in. So honored and grateful...
Would you feel comfortable sharing your biosketch (I could also email you my work-in-progress document)? I'm at the gathering-ideas phase right now, and am not entirely sure what's permitted vs not...
February 1, 2026 at 6:22 PM
Would you feel comfortable sharing your biosketch (I could also email you my work-in-progress document)? I'm at the gathering-ideas phase right now, and am not entirely sure what's permitted vs not...
I have the same question: The instructions says "There is no specific format for referencing the products in this section" and then also says "Do not provide citations on the NIH Biographical Sketch Supplement." π΅βπ« #confused
February 1, 2026 at 6:06 PM
I have the same question: The instructions says "There is no specific format for referencing the products in this section" and then also says "Do not provide citations on the NIH Biographical Sketch Supplement." π΅βπ« #confused
I'm particularly unclear about how to cite papers in the "Contributions to Science" section. Any ideas, @ernstlaboratory.bsky.social or others?
February 1, 2026 at 6:05 PM
I'm particularly unclear about how to cite papers in the "Contributions to Science" section. Any ideas, @ernstlaboratory.bsky.social or others?
Are any of you happy with how your ScienCV-generated biosketch looks? I'm not quite satisfied with mine (formatting, flow, etc), and would love to look at other examples for customization ideas! Please message me if you'd be willing to swap biosketches (confidentially, of course)!
February 1, 2026 at 4:36 PM
Are any of you happy with how your ScienCV-generated biosketch looks? I'm not quite satisfied with mine (formatting, flow, etc), and would love to look at other examples for customization ideas! Please message me if you'd be willing to swap biosketches (confidentially, of course)!
Oh wow, I didn't realize that that was the name of the restaurant! I thought you were just naming an item on the menu! π
January 31, 2026 at 7:47 PM
Oh wow, I didn't realize that that was the name of the restaurant! I thought you were just naming an item on the menu! π
Thanks! Which restaurant?
January 31, 2026 at 7:40 PM
Thanks! Which restaurant?
Love to see insights arising from unique and fascinating analyses of existing massive datasets! π
Today in @nature.com, we describe how discarded reads in biobank-scale WGS can help resolve the genetic predictors and consequences of Epstein-Barr Virus (EBV) infection.
Wonderful working with @ryandhindsa.bsky.social @sherrynyeo.bsky.social @erinmayc.bsky.social
www.nature.com/articles/s41...
Wonderful working with @ryandhindsa.bsky.social @sherrynyeo.bsky.social @erinmayc.bsky.social
www.nature.com/articles/s41...
Population-scale sequencing resolves determinants of persistent EBV DNA - Nature
Population-scale WGS reveals genetic determinants of persistent EBV DNA, linking immune regulationβespecially antigen processing and MHC class II variationβto EBV persistence and heterogeneous di...
www.nature.com
January 28, 2026 at 5:28 PM
Love to see insights arising from unique and fascinating analyses of existing massive datasets! π
Credit where credit is due! NCBI helpdesk replied a week after my initial request, and merged my two accounts. I can now make my ScienCV Biosketch!
Just realized that the glitches I'm having with ScienCV are because I have two NCBI accounts... My ORCiD is linked to the obsolete acct, which means that I can't link it to my current acct... I've send a message to NCBI support desk to merge accts, and I hope they are staffed enough to respond...
January 27, 2026 at 4:13 PM
Credit where credit is due! NCBI helpdesk replied a week after my initial request, and merged my two accounts. I can now make my ScienCV Biosketch!
If this nation has a conscience, what will it take to shake it from its slumber?
A video of Alex Pretti reading out the final salute of an unnamed veteran he cared for until the end of his life in the ICU, posted to Facebook by his son.
January 25, 2026 at 9:32 PM
If this nation has a conscience, what will it take to shake it from its slumber?
Congratulations to Aishwarya Pawar (@aishwarya2510.bsky.social), @cambupenn.bsky.social PhD graduate from our lab, for the 2025 Kadesch Prize in Genetics. This award, in honor of Tom Kadesch (former chair of @penngenetics.bsky.social) honors graduate student excellence in research & citizenship.
January 23, 2026 at 7:57 PM
Congratulations to Aishwarya Pawar (@aishwarya2510.bsky.social), @cambupenn.bsky.social PhD graduate from our lab, for the 2025 Kadesch Prize in Genetics. This award, in honor of Tom Kadesch (former chair of @penngenetics.bsky.social) honors graduate student excellence in research & citizenship.
Congratulations to Charles Antony (@cantony07.bsky.social), Research Associate in our lab, for being awarded a 2026 American Society of Hematology (ASH) Fellow to Faculty Scholar Award for his investigations into ribosomal RNA transcription in hematopoiesis! Many thanks to ASH for this honor! #ASH
January 23, 2026 at 7:51 PM
Congratulations to Charles Antony (@cantony07.bsky.social), Research Associate in our lab, for being awarded a 2026 American Society of Hematology (ASH) Fellow to Faculty Scholar Award for his investigations into ribosomal RNA transcription in hematopoiesis! Many thanks to ASH for this honor! #ASH
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January 18, 2026 at 5:26 PM
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Just realized that the glitches I'm having with ScienCV are because I have two NCBI accounts... My ORCiD is linked to the obsolete acct, which means that I can't link it to my current acct... I've send a message to NCBI support desk to merge accts, and I hope they are staffed enough to respond...
January 17, 2026 at 1:04 PM
Just realized that the glitches I'm having with ScienCV are because I have two NCBI accounts... My ORCiD is linked to the obsolete acct, which means that I can't link it to my current acct... I've send a message to NCBI support desk to merge accts, and I hope they are staffed enough to respond...
Reposted by Vikram Paralkar
Portrait of @nobelprize.org laureate Carol Greider for the @nationalacademies.org.
Alongside her mentor Elizabeth Blackburn, Dr Greider identified telomerase, an enzyme that maintains the protective caps at the ends of chromosomes known as telomeres.
More: explorers.com/carol-grieder/ #SciArt
Alongside her mentor Elizabeth Blackburn, Dr Greider identified telomerase, an enzyme that maintains the protective caps at the ends of chromosomes known as telomeres.
More: explorers.com/carol-grieder/ #SciArt
January 16, 2026 at 2:00 PM
Portrait of @nobelprize.org laureate Carol Greider for the @nationalacademies.org.
Alongside her mentor Elizabeth Blackburn, Dr Greider identified telomerase, an enzyme that maintains the protective caps at the ends of chromosomes known as telomeres.
More: explorers.com/carol-grieder/ #SciArt
Alongside her mentor Elizabeth Blackburn, Dr Greider identified telomerase, an enzyme that maintains the protective caps at the ends of chromosomes known as telomeres.
More: explorers.com/carol-grieder/ #SciArt
If you're published in eLife they should at least give you water!
January 15, 2026 at 4:55 PM
If you're published in eLife they should at least give you water!
Congratulations, Vijay!
January 2, 2026 at 4:00 PM
Congratulations, Vijay!