Karolin Luger
@nucleosomepolice.bsky.social
Chromatin and cryoEM afficionada. Still a fan of crystallography. Avid Colorado hiker. Will call out ugly nucleosome cartoons. Come for the science, stay for the mountain pictures and snark. Opinions and snark are my own.
Pinned
Histone PARylation factor 1: a review of its role in the DNA damage response
Abstract. Although poly-(ADP ribose) polymerase 1 (PARP1) and PARylation of histones have been known for over 50 years and have been successfully targeted
academic.oup.com
Beautiful review from J. Rudolph on Histone PARylation factor 1: a review of its role in the DNA damage response url: academic.oup.com/nar/article/...
Reposted by Karolin Luger
Tradescantia occidentalis, our Western Spiderwort, blooming in my yard #nativeplants
#FallbackFlowers #Fallback to June 5 🌿
#FallbackFlowers #Fallback to June 5 🌿
December 5, 2025 at 4:18 PM
Tradescantia occidentalis, our Western Spiderwort, blooming in my yard #nativeplants
#FallbackFlowers #Fallback to June 5 🌿
#FallbackFlowers #Fallback to June 5 🌿
#quiltsky, i'd be curious to learn how you all are using AI in your quilting design (eg hacking of pattern, fabric calculations, design....) - lets get the conversation going!
December 5, 2025 at 4:22 PM
#quiltsky, i'd be curious to learn how you all are using AI in your quilting design (eg hacking of pattern, fabric calculations, design....) - lets get the conversation going!
re #fifa 'peace prize' and who is expected to 'win' it: those of you who raised kids know the trick: - 'here is shiny new thing that is even BETTER than the shiny thing that for so many reasons you cannot have'..... sometimes works with 2-4 year olds. pathetic.
December 5, 2025 at 2:23 PM
re #fifa 'peace prize' and who is expected to 'win' it: those of you who raised kids know the trick: - 'here is shiny new thing that is even BETTER than the shiny thing that for so many reasons you cannot have'..... sometimes works with 2-4 year olds. pathetic.
Reposted by Karolin Luger
@science.org 🧬🔬 Multiscale structure of #chromatin condensates explains phase separation and material properties | Science www.science.org/doi/10.1126/... @janhuemar.bsky.social et al.
Multiscale structure of chromatin condensates explains phase separation and material properties
The structure and interaction networks of molecules within biomolecular condensates are poorly understood. Using cryo–electron tomography and molecular dynamics simulations, we elucidated the structur...
www.science.org
December 5, 2025 at 5:24 AM
@science.org 🧬🔬 Multiscale structure of #chromatin condensates explains phase separation and material properties | Science www.science.org/doi/10.1126/... @janhuemar.bsky.social et al.
Reposted by Karolin Luger
My department at California State University Northridge is hiring! We're looking for a new colleague studying microbiology or molecular/cellular biology. I'm not on the search committee, but happy to answer questions about the department and campus, and life in LA
buff.ly/Pc1KOaC
buff.ly/Pc1KOaC
Career Opportunities
Applicant Log-In
careers.pageuppeople.com
December 4, 2025 at 7:19 PM
My department at California State University Northridge is hiring! We're looking for a new colleague studying microbiology or molecular/cellular biology. I'm not on the search committee, but happy to answer questions about the department and campus, and life in LA
buff.ly/Pc1KOaC
buff.ly/Pc1KOaC
Reposted by Karolin Luger
Feeling festive?
Why not deck the halls with @cvrinfo.bsky.social's papercraft #VirusSnowflakes and celebrate the science of viruses and the fight against viral diseases.
Download for free: cvr-engagement.co.uk/virus-snowfl...
#scicomm #sciart #decorations
Why not deck the halls with @cvrinfo.bsky.social's papercraft #VirusSnowflakes and celebrate the science of viruses and the fight against viral diseases.
Download for free: cvr-engagement.co.uk/virus-snowfl...
#scicomm #sciart #decorations
December 1, 2025 at 9:51 AM
Feeling festive?
Why not deck the halls with @cvrinfo.bsky.social's papercraft #VirusSnowflakes and celebrate the science of viruses and the fight against viral diseases.
Download for free: cvr-engagement.co.uk/virus-snowfl...
#scicomm #sciart #decorations
Why not deck the halls with @cvrinfo.bsky.social's papercraft #VirusSnowflakes and celebrate the science of viruses and the fight against viral diseases.
Download for free: cvr-engagement.co.uk/virus-snowfl...
#scicomm #sciart #decorations
Reposted by Karolin Luger
Calypso bulbosa, our Fairy Slipper orchid, blooming on the Ceran St. Vrain trail #orchids #nativeplants
#FallBackFlowers #FallBack to June 4 🌿
#FallBackFlowers #FallBack to June 4 🌿
December 4, 2025 at 3:06 PM
Calypso bulbosa, our Fairy Slipper orchid, blooming on the Ceran St. Vrain trail #orchids #nativeplants
#FallBackFlowers #FallBack to June 4 🌿
#FallBackFlowers #FallBack to June 4 🌿
it is the season of giving.. maybe even to yourself! fantastic pieces!
Small business spotlight...
Palms Trading Company is a family-owned business in #Albuquerque that specializes in authentic, handcrafted Native American Indian art. Founded in 1933, Palms is known for its selection of high-quality items, guaranteed authenticity & pricing - www.palmstrading.com
Palms Trading Company is a family-owned business in #Albuquerque that specializes in authentic, handcrafted Native American Indian art. Founded in 1933, Palms is known for its selection of high-quality items, guaranteed authenticity & pricing - www.palmstrading.com
December 3, 2025 at 9:16 PM
it is the season of giving.. maybe even to yourself! fantastic pieces!
my new go-to name for name-calling purposes.
It’s the bird whose name sounds like a Shakespearean insult!!!
A Yellow-bellied Sapsucker for #WoodpeckerWednesday. #birds 🌿
A Yellow-bellied Sapsucker for #WoodpeckerWednesday. #birds 🌿
December 3, 2025 at 9:13 PM
my new go-to name for name-calling purposes.
December 3, 2025 at 3:09 PM
add my WTF to the collective. WTF.
The former oil executive/DOE official who held the all-staff meeting announcing the change repeatedly told the scientists who work on clean energy that she "hates" clean energy.
'A Collective WTF': National Renewable Energy Laboratory Gets a Trumpian Name Change
NREL employees, many of whom joined the lab specifically to work toward its clean energy mission, are not happy about the oil-soaked leadership's moves.
www.gravityisgone.com
December 2, 2025 at 10:29 PM
add my WTF to the collective. WTF.
if y'all arent follwing @frwildflowers.bsky.social you are missing out on fantastic #plant pictures native to #colorado.
Oenothera caespitosa, our Tufted Evening Primrose, blooming with spider in Boulder Canyon #nativeplants
#FallBackFlowers #FallBack to June 2 🌿
#FallBackFlowers #FallBack to June 2 🌿
December 2, 2025 at 5:34 PM
if y'all arent follwing @frwildflowers.bsky.social you are missing out on fantastic #plant pictures native to #colorado.
you go girls! Austrian nuns raise a ruckus. www.npr.org/2025/12/01/g...
Austria's rebel nuns refuse to give up Instagram to stay in their convent
The trio of octogenarian nuns gained global fame after fleeing their care home and breaking into their former convent. Now their superior has asked the Vatican to intercede in the dispute.
www.npr.org
December 2, 2025 at 5:15 PM
you go girls! Austrian nuns raise a ruckus. www.npr.org/2025/12/01/g...
Reposted by Karolin Luger
Yesterday was #WorldAIDSDay. It's the first time since its inception in 1988 that the US has not formally recognized it.
December 2, 2025 at 4:55 PM
Yesterday was #WorldAIDSDay. It's the first time since its inception in 1988 that the US has not formally recognized it.
Reposted by Karolin Luger
Oenothera caespitosa, our Tufted Evening Primrose, blooming with spider in Boulder Canyon #nativeplants
#FallBackFlowers #FallBack to June 2 🌿
#FallBackFlowers #FallBack to June 2 🌿
December 2, 2025 at 3:23 PM
Oenothera caespitosa, our Tufted Evening Primrose, blooming with spider in Boulder Canyon #nativeplants
#FallBackFlowers #FallBack to June 2 🌿
#FallBackFlowers #FallBack to June 2 🌿
immigrants... get the job done!
Electronic engineer Joy Lim Arthur was born 90 years ago today in Manila, traveling to the United States in the 1950s for college. After graduation, she spent her career working for the US Army on methods to protect soldiers from electronic warfare.
#WomenInSTEM #Engineering 🧪🔌
#WomenInSTEM #Engineering 🧪🔌
December 2, 2025 at 3:05 PM
immigrants... get the job done!
Reposted by Karolin Luger
New York Times article on science funding with some depressing but familiar curves with interactive graphics.
www.nytimes.com/interactive/...
www.nytimes.com/interactive/...
The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine (Gift Article)
A quiet policy change means the government is making fewer bets on long-term science.
www.nytimes.com
December 2, 2025 at 11:57 AM
New York Times article on science funding with some depressing but familiar curves with interactive graphics.
www.nytimes.com/interactive/...
www.nytimes.com/interactive/...
Question to y'all #protein experts: we used to do limited proteolysis, then N-terminal sequencing to see where domains are in proteins. no more N-terminal sequencing. 1) why doesnt anyone do Edman any more? 2) what is the most accurate / feasible / cost effective way to do this now?
December 1, 2025 at 1:40 PM
Question to y'all #protein experts: we used to do limited proteolysis, then N-terminal sequencing to see where domains are in proteins. no more N-terminal sequencing. 1) why doesnt anyone do Edman any more? 2) what is the most accurate / feasible / cost effective way to do this now?
Reposted by Karolin Luger
The world has lost a giant of virology, molecular biology and science advocacy
David Baltimore’s obituary by Stephen Goff www.nature.com/articles/d41...
David Baltimore’s obituary by Stephen Goff www.nature.com/articles/d41...
David Baltimore obituary: virologist whose enzyme discovery transformed understanding of cancer and HIV/AIDS
The protein, reverse transcriptase, has become an essential tool for making DNA copies of RNA.
www.nature.com
December 1, 2025 at 1:25 PM
The world has lost a giant of virology, molecular biology and science advocacy
David Baltimore’s obituary by Stephen Goff www.nature.com/articles/d41...
David Baltimore’s obituary by Stephen Goff www.nature.com/articles/d41...
Reposted by Karolin Luger
And now confirmation of the liquid nature of viral factories for poxviridae.
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Poxvirus H5 mediates the formation of liquid-liquid phase separation condensates which promote virus factory assembly
Author summary In this study, we investigate the role of a protein called H5 from the vaccinia virus in the formation of structures inside infected cells known as viral factories. These viral factorie...
journals.plos.org
November 21, 2025 at 6:00 AM
And now confirmation of the liquid nature of viral factories for poxviridae.
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
i am here for this
November 30, 2025 at 3:52 PM
i am here for this
Reposted by Karolin Luger
Here’s this year’s Books We Love—but thanks to lots of work by lots of people, you can also look over all the Books We Love years back to 2013. It’s a remarkable project, and I can say that because I have nothing to do with it. (/fin)
Books We Love
Here are 380+ great reads from 2025 handpicked just for you by NPR staffers and trusted critics.
apps.npr.org
November 30, 2025 at 1:54 PM
Here’s this year’s Books We Love—but thanks to lots of work by lots of people, you can also look over all the Books We Love years back to 2013. It’s a remarkable project, and I can say that because I have nothing to do with it. (/fin)
Reposted by Karolin Luger
It’s officially Denver’s first snow of the season!
A whopping 0.2” at DIA = we’re on the board. First measurable snow since April 18 (225 days).
❄️ 2nd-latest first snow of the season (12/10/21).
❄️ 225 snowless days = T-3rd-longest snowless on record for Denver.
#COwx
A whopping 0.2” at DIA = we’re on the board. First measurable snow since April 18 (225 days).
❄️ 2nd-latest first snow of the season (12/10/21).
❄️ 225 snowless days = T-3rd-longest snowless on record for Denver.
#COwx
November 29, 2025 at 2:51 PM
It’s officially Denver’s first snow of the season!
A whopping 0.2” at DIA = we’re on the board. First measurable snow since April 18 (225 days).
❄️ 2nd-latest first snow of the season (12/10/21).
❄️ 225 snowless days = T-3rd-longest snowless on record for Denver.
#COwx
A whopping 0.2” at DIA = we’re on the board. First measurable snow since April 18 (225 days).
❄️ 2nd-latest first snow of the season (12/10/21).
❄️ 225 snowless days = T-3rd-longest snowless on record for Denver.
#COwx
