Author | Lightnews

Vilja Oired @oired.bsky.social · 20d

Vilja Oired @oired.bsky.social · Sep 7

Selection bias could be the cause. But artificial sweeteners trigger insulin: A) Short term they move sugar into non-brain cells, causing relative brain hypoglycemia. B) Long term they drive insulin resistance, with or without meeting diabetes criteria, but cognitive decline expected.

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Vilja Oired @oired.bsky.social · Jul 5

Interesting🤔

How do vaccines reduce the risk of dementia? | University of Oxford

A new study by the University of Oxford, published in the journal npj Vaccines, shows that a vaccine against respiratory syncytial virus (RSV) is associated with a 29% reduction in dementia risk in

www.ox.ac.uk

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Vilja Oired @oired.bsky.social · Jun 6

Like much of human nature, it’s a question of trust - just like when elevators first switched from human operators to automation. People were skeptical, even afraid. Now, no one asks for a lift operator.

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Vilja Oired @oired.bsky.social · Jun 3

Robotic surgery outperforms laparoscopic in rectal cancer. Next step: train robots using AI like that in self-driving cars and humanoids. How long before an AI-driven robot beats the surgeon-controlled one?

JAMA @jama.com · Jun 2

Robotic surgery for middle or low rectal cancer demonstrated lower 3-year locoregional recurrence rates and improved functional outcomes compared to conventional laparoscopic surgery.

#ASCO25

https://ja.ma/4mGtyBh

Figure 2. Oncological Outcomes at 3 Years

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Vilja Oired @oired.bsky.social · May 23

Excess death in US compared to other high-income countries. This trend can probably only be broken by the Ozempic-pandemic🤔 and maybe some sensible healthcare reforms💡.

Excess US Deaths Before, During, and After the COVID-19 Pandemic

This cohort study examines trends in excess deaths in the US before, during, and after the COVID-19 pandemic.

jamanetwork.com

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Vilja Oired @oired.bsky.social · May 23

Superhuman performance of a large language model on the reasoning tasks of a physician.

arxiv.org/abs/2412.10849

Reposted by Vilja Oired

Journal of the American Geriatrics Society (JAGS) @agsjournal.bsky.social · May 16

Hospitalized patients with dementia are infrequently present in GOC conversations and less likely to have their values and preferences for medical care documented within a GOC note. #geriatrics #palliativecare agsjournals.onlinelibrary.wiley.com/doi/10.1111/...

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Vilja Oired @oired.bsky.social · May 15

Human(?) development is about to jump to hyperspace. With small tweaks, this could be applied to everything from scientific research to factory floors and logistics.

DeepMind unveils ‘spectacular’ general-purpose science AI

System improves chip designs and tackles unsolved maths problems, but has not been rolled out to researchers outside the company.

www.nature.com

Reposted by Vilja Oired

NEJM.org @nejm.org · May 11

“Our study demonstrated associations between obesity, particularly severe obesity, and the incidence of 16 common health outcomes.” 📋 Read the full study results by Z. Yao et al. in NEJM Evidence: eviden.cc/4iIRjGg

#MedSky #EndoSky

$A graph showing the adjusted population-attributable fraction of obesity classes for prevalent health conditions$

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Reposted by Vilja Oired

AHA Science @ahascience.bsky.social · Apr 21

Heart and Kidney disease are related. Many patients have both, leading to CKM syndrome. http://spr.ly/6048uP0fo

As many as 9 in 10 adults with CKD don't know they have it. Kidney disease usually has 0 symptoms, & many people don’t know they have it until it’s very advanced.

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Reposted by Vilja Oired

Mikael Ehrnström @mickeehrnstrom.bsky.social · Apr 15

Symptom support, unbiased and pure. Taking on the toughest cases: elderly patients. Get diagnoses and suggested investigations. Powered by our own AI (not Big Tech), but we use LLM as a sidekick. Easy, no login, free to use: Oired.com

Oired

Introducing Oired, a symptom checker designed with the elderly in mind

Oired.com

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Reposted by Vilja Oired

NEJM.org @nejm.org · Apr 13

In the API-CAT trial involving patients with active cancer and venous thromboembolism, extended anticoagulation with reduced-dose apixaban was noninferior to full-dose apixaban for preventing recurrent thromboembolic events. Full trial results and Research Summary: nej.md/41YkRZK

#MedSky

The New England Journal of Medicine
Extended Reduced-Dose Apixaban for Cancer-Associated VTE
A Research Summary based on Mahé I et al. | 10.1056/NEJMoa2416112 | Published on March 29, 2025

Visual representations of the patients in the trial and the treatments they were assigned.

Read the full Research Summary at NEJM.org.

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Vilja Oired @oired.bsky.social · Apr 8

In Type 2 Diabetes SLGT2 decreased risk of Alzheimer with 43% and GLP-1 with 33% compared with other DM2 medications. No significant difference between SLGT2 and GLP-1.

jamanetwork.com/journals/jam...

Vilja Oired @oired.bsky.social · Apr 7

Read, learn, think and challenge yourself should be added throughout life.

Ian Kremer @leadcoalition.bsky.social · Apr 7

Help Reduce Your Risks of #Dementia

#Alzheimers #health #publichealth

Help Reduce Your Risks of Dementia – Things You Might Be Able To Change

Early Life

* More Education

Mid Life

* Manage Blood Pressure
* Prevent & Treat Hearing Loss
* Keep a Healthy Weight for Your Body
* Prevent Head Injury
* Limit Alcohol

Later Life

* Do Not Smoke
* Connect with Friends & Family
* Be Active
* Avoid Air Pollution
* Treat Depression
* Manage Diabetes

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Vilja Oired @oired.bsky.social · Apr 2

Zoster vaccine reduced the probability of a new dementia diagnosis by approximately 20% over a seven-year follow-up period.

A natural experiment on the effect of herpes zoster vaccination on dementia - Nature

Using a natural experiment that avoids common bias concerns, this study finds that the live-attenuated shingles vaccine reduced the probability of a new dementia diagnosis within a follow-up period of...

www.nature.com

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Vilja Oired @oired.bsky.social · Apr 1

”On average, each dollar spent on vaccination yields a hefty $54 in returns.” - That is a good investment!

First, jab more babies

As aid shrinks, donors and recipients should focus more on health

economist.com

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Vilja Oired @oired.bsky.social · Apr 1

NEJM: Global Effect of Cardiovascular Risk Factors on Lifetime Estimates. With all 5 risk factors (high blood pressure, high cholesterol, diabetes, smoking, and unhealthy body weight) at age 50 lifetime cardiovascular disease risk was 38% in men and 24% in women.

www.nejm.org/doi/full/10....

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Vilja Oired @oired.bsky.social · Apr 1

Treating coronary artery disease risk factors early could make it a rare disease. But are we ready to take pills to prevent a disease that might occur 40 years later? Of course, a middle way already exists in clinical practice. However, this Lancet Commission rightly highlights prevention.

The Lancet @thelancet.com · Apr 1

🆕 Coronary artery disease (CAD) remains a leading cause of global morbidity & mortality.

A Lancet Commission redefines CAD, emphasising early detection, risk factor management, & a comprehensive approach to prevention throughout the life course: tinyurl.com/5axhtr85 #ACC25 #MedSky

Promotional card for the Lancet Commission on rethinking coronary artery disease: moving from ischaemia to atheroma. Background image depicts a blood clot.

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Vilja Oired @oired.bsky.social · Mar 26

About to retire, prepare yourself or risk cognitive decline.

Retirement Can Harm Your Brain. Here’s How to Keep It Healthy.

It’s challenging to stay mentally sharp and healthy through the major transition. Careful planning is key.

www.nytimes.com

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Vilja Oired @oired.bsky.social · Mar 25

The number of geriatricians is shrinking, just 7,400 in 2022, down from 10,000 in 2000, while the aging population keeps growing. The American Geriatrics Society says we’ll need 30,000 by 2030. The math isn’t adding up!

America's aging population faces a growing shortage of geriatric care

For a variety of reasons, geriatric care experts told BI it's been hard attracting new doctors to the field. It's a problem for an aging US population.

www.businessinsider.com

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Reposted by Vilja Oired

Eric Topol @erictopol.bsky.social · Mar 23

A pie graph worth keeping in mind as the NIH budget plummets jamanetwork.com/journals/jam... for 356 new FDA drugs approved

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Reposted by Vilja Oired

Ian Kremer @leadcoalition.bsky.social · Mar 24

#Kindness cannot prevent, slow or cure #Alzheimers. But the presence or absence of kindness fundamentally changes quality of life for people experiencing #dementia and those who are #caregiving.

#quote

"Kindness is like snow—it beautifies everything it covers."

~ Khalil Gibran

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Vilja Oired @oired.bsky.social · Mar 23

Or could the relative decline in dementia be partly due to the increasing use of smartphones among older people? A constant flow of information and interactions, which stimulate thought and keep the brain active, proven by how hard it is to get someone’s attention when they’re on their phone.

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Vilja Oired @oired.bsky.social · Mar 18

Gene repair inside the human body is now a reality.

Science Magazine @science.org · Mar 17

For the first time, researchers have used the #CRISPR gene editor to repair a flawed gene in the human body. scim.ag/3RdMzMT

Gene editing fixes DNA—and treats incurable lung and liver disease

A promising clinical trial marks another milestone for the CRISPR gene editor

scim.ag

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