Hugo Bisio
@molbiolgv.bsky.social
#Free-palestina. #Respect-venezuela #Respect-south-America. #f@ Trump. Molecular biologist digging into Giant Virus genomes at the IGS. 🏳️🌈🇺🇾👨🔬🌎 Views and opinions are my own
Pinned
Hugo Bisio
@molbiolgv.bsky.social
· Oct 15
Elucidating the interaction network of one of the largest icosahedral capsids in the virosphere
Giant viruses challenge traditional boundaries of virology with their large particle sizes, complex genomes, and unique replication strategies. Yet, despite its 750 nm diameter and incorporation of do...
www.biorxiv.org
The latest preprint from the lab is out!
Here we used structural clustering and immunoprecipitations to uncover some networks in our knowledge of giant virons proteomes. An interesting story by Hela Safi and @ambsch.bsky.social.
www.biorxiv.org/content/10.1...
Here we used structural clustering and immunoprecipitations to uncover some networks in our knowledge of giant virons proteomes. An interesting story by Hela Safi and @ambsch.bsky.social.
www.biorxiv.org/content/10.1...
Reposted by Hugo Bisio
Reposted by Hugo Bisio
The boats the regime is claiming are going from Venezuela to the US would need to refuel over 20 times to get to Miami.
They are lying to us.
They are lying to us.
December 3, 2025 at 5:40 PM
The boats the regime is claiming are going from Venezuela to the US would need to refuel over 20 times to get to Miami.
They are lying to us.
They are lying to us.
And there we go... Assholes www.euronews.com/my-europe/20...
Rutte: US to make €4.3bn in weapons sales for Ukraine through NATO
Washington more or less stopped deliveries of weapons to Ukraine this summer, instead calling on Europeans to purchase equipment and donate it themselves – and Ukraine's allies have so far obliged to ...
www.euronews.com
December 3, 2025 at 6:12 PM
And there we go... Assholes www.euronews.com/my-europe/20...
Reposted by Hugo Bisio
immigrants... get the job done!
Electronic engineer Joy Lim Arthur was born 90 years ago today in Manila, traveling to the United States in the 1950s for college. After graduation, she spent her career working for the US Army on methods to protect soldiers from electronic warfare.
#WomenInSTEM #Engineering 🧪🔌
#WomenInSTEM #Engineering 🧪🔌
December 2, 2025 at 3:05 PM
immigrants... get the job done!
Reposted by Hugo Bisio
Excited to release the Herculean efforts of @scottchisholm.bsky.social &Co. defining the subcellular #hyperLOPIT spatial proteome of #Plasmodium schizonts. Proteomes defining 24 subcellular niches, including exported compartments in the blood cell, are identified.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
November 28, 2025 at 8:30 AM
Excited to release the Herculean efforts of @scottchisholm.bsky.social &Co. defining the subcellular #hyperLOPIT spatial proteome of #Plasmodium schizonts. Proteomes defining 24 subcellular niches, including exported compartments in the blood cell, are identified.
www.biorxiv.org/content/10.1...
www.biorxiv.org/content/10.1...
Reposted by Hugo Bisio
I was one of those immigrants, and we commit fewer crimes than people born here.
“Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the US by revoking their legal status.”
apnews.com/article/trum...
“Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the US by revoking their legal status.”
apnews.com/article/trum...
Trump says he wants to 'permanently pause' migration to the US from poorer countries
President Donald Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the United States by revoking their legal status...
apnews.com
November 28, 2025 at 3:19 PM
I was one of those immigrants, and we commit fewer crimes than people born here.
“Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the US by revoking their legal status.”
apnews.com/article/trum...
“Trump says he wants to “permanently pause migration” from poorer nations and is promising to seek to expel millions of immigrants from the US by revoking their legal status.”
apnews.com/article/trum...
Reposted by Hugo Bisio
Check out our latest paper on mirusviruses, one of the most remarkable new groups of protist viruses - extremely diverse, carry lots of spliceosomal introns (including new homing introns) and are at the evolutionary crossroads between tailed phages and herpesviruses! www.nature.com/articles/s41...
Widespread and intron-rich mirusviruses are predicted to reproduce in nuclei of unicellular eukaryotes - Nature Microbiology
Environmental metagenomic explorations show that Mirusviricota lineages lack essential replication and transcription genes and contain spliceosomal introns, suggesting nuclear reproduction.
www.nature.com
November 28, 2025 at 4:43 PM
Check out our latest paper on mirusviruses, one of the most remarkable new groups of protist viruses - extremely diverse, carry lots of spliceosomal introns (including new homing introns) and are at the evolutionary crossroads between tailed phages and herpesviruses! www.nature.com/articles/s41...
Reposted by Hugo Bisio
The war continues. Don't be fooled. www.euronews.com/2025/11/21/i...
Israel plans to seize major archaeological site in the West Bank
The move coincided with the establishment of a new illegal outpost by Israeli settlers near Bethlehem and comes as the Israeli government faces growing pressure to crackdown on settler violence.
www.euronews.com
November 21, 2025 at 7:56 AM
The war continues. Don't be fooled. www.euronews.com/2025/11/21/i...
And now confirmation of the liquid nature of viral factories for poxviridae.
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Poxvirus H5 mediates the formation of liquid-liquid phase separation condensates which promote virus factory assembly
Author summary In this study, we investigate the role of a protein called H5 from the vaccinia virus in the formation of structures inside infected cells known as viral factories. These viral factorie...
journals.plos.org
November 21, 2025 at 6:00 AM
And now confirmation of the liquid nature of viral factories for poxviridae.
journals.plos.org/plospathogen...
journals.plos.org/plospathogen...
Reposted by Hugo Bisio
Is it a flagellate? A tiny ball with tentacles? Contamination in my ciliate culture? NEW SUPERGROUP OF EUKARYOTES? Yes to all 4! Meet Solarion - just out in #Nature doi.org/10.1038/s415... Huge congrats to Marek Valt, Cepicka Lab & the star team! Very happy to be part of this project. #ProtistsOnSky
November 19, 2025 at 9:39 PM
Is it a flagellate? A tiny ball with tentacles? Contamination in my ciliate culture? NEW SUPERGROUP OF EUKARYOTES? Yes to all 4! Meet Solarion - just out in #Nature doi.org/10.1038/s415... Huge congrats to Marek Valt, Cepicka Lab & the star team! Very happy to be part of this project. #ProtistsOnSky
Reposted by Hugo Bisio
Where Do #Viruses Come From? ...
| #genomics | #Duplodnaviria | #virus | #DNA | #RNA | By @kamalnahas.bsky.social via the-scientist .com
| #genomics | #Duplodnaviria | #virus | #DNA | #RNA | By @kamalnahas.bsky.social via the-scientist .com
Where Do Viruses Come From?
Using genomics, evolutionary biologists test several hypotheses on the origin of viruses. New evidence suggests they may have emerged more times than previously thought.
www.the-scientist.com
November 13, 2025 at 10:01 PM
Where Do #Viruses Come From? ...
| #genomics | #Duplodnaviria | #virus | #DNA | #RNA | By @kamalnahas.bsky.social via the-scientist .com
| #genomics | #Duplodnaviria | #virus | #DNA | #RNA | By @kamalnahas.bsky.social via the-scientist .com
Reposted by Hugo Bisio
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
November 7, 2025 at 10:44 AM
An Asgard archaeon with internal membrane compartments
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Brilliant study led by @fmacleod.bsky.social and Andriko von Kügelgen. Tight collaboration with @buzzbaum.bsky.social and lab. Congrats to all authors!
www.biorxiv.org/content/10.1...
Reposted by Hugo Bisio
Diatom ultrastructural diversity across controlled and natural environments: Current Biology www.cell.com/current-biol... @currentbiology.bsky.social
Diatom ultrastructural diversity across controlled and natural environments
Flori et al. establish high-resolution and generalizable immunofluorescence in cultured
and environmental diatoms, thanks to 4-fold cryo-expansion microscopy. This represents
a step-change for compara...
www.cell.com
November 1, 2025 at 6:41 PM
Diatom ultrastructural diversity across controlled and natural environments: Current Biology www.cell.com/current-biol... @currentbiology.bsky.social
Reposted by Hugo Bisio
It’s outrageous they’re killing innocent people, but we also need to stress, every time, that it would not really matter even it were absolutely certain that they were drug traffickers. Murdering criminals is still, you know, murder.
The government has killed 32 people in 7 strikes with no evidence they were traffickers. The admiral leading the mission quit. If we had proof, they’d face a court, not a drone.
The law still applies, even to suspected drug traffickers, and right now, the Administration’s story isn’t adding up.
The law still applies, even to suspected drug traffickers, and right now, the Administration’s story isn’t adding up.
October 22, 2025 at 1:45 AM
It’s outrageous they’re killing innocent people, but we also need to stress, every time, that it would not really matter even it were absolutely certain that they were drug traffickers. Murdering criminals is still, you know, murder.
Reposted by Hugo Bisio
-A living wage
-Guaranteed healthcare
-The right to join a union
-The right to vote
-The right to choose when, how, and with whom you start a family
-The right for you and your family to live free from gun violence
These are the foundations of real freedom.
-Guaranteed healthcare
-The right to join a union
-The right to vote
-The right to choose when, how, and with whom you start a family
-The right for you and your family to live free from gun violence
These are the foundations of real freedom.
October 20, 2025 at 6:01 PM
-A living wage
-Guaranteed healthcare
-The right to join a union
-The right to vote
-The right to choose when, how, and with whom you start a family
-The right for you and your family to live free from gun violence
These are the foundations of real freedom.
-Guaranteed healthcare
-The right to join a union
-The right to vote
-The right to choose when, how, and with whom you start a family
-The right for you and your family to live free from gun violence
These are the foundations of real freedom.
Reposted by Hugo Bisio
🤭🤭🤭
October 19, 2025 at 11:03 AM
🤭🤭🤭
Reposted by Hugo Bisio
The world joined us and said, “No Kings.”
October 19, 2025 at 4:17 AM
The world joined us and said, “No Kings.”
Reposted by Hugo Bisio
As seen at No Kings Atlanta:
October 18, 2025 at 7:05 PM
As seen at No Kings Atlanta:
Reposted by Hugo Bisio
October 18, 2025 at 5:21 PM
Reposted by Hugo Bisio
Our work on viruses and virus satellites of haloarchaea and their DPANN symbionts is out today in Nature Microbiology!
@mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social
www.nature.com/articles/s41...
@mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social
www.nature.com/articles/s41...
Viruses and virus satellites of haloarchaea and their nanosized DPANN symbionts reveal intricate nested interactions - Nature Microbiology
An exploration of the viromes of haloarchaea and their ultra-small DPANN symbionts reveals plasmid-derived satellites of viruses from both archaeal groups, highlighting the complexity of nested symbio...
www.nature.com
October 17, 2025 at 9:54 AM
Our work on viruses and virus satellites of haloarchaea and their DPANN symbionts is out today in Nature Microbiology!
@mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social
www.nature.com/articles/s41...
@mkrupovic.bsky.social @deemteam.bsky.social @anagtz.bsky.social
www.nature.com/articles/s41...
Reposted by Hugo Bisio
1/10 Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from?
Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria.
www.biorxiv.org/content/10.1...
Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria.
www.biorxiv.org/content/10.1...
Antiviral reverse transcriptases reveal the evolutionary origin of telomerase
Defense-associated reverse transcriptases (DRTs) employ diverse and distinctive mechanisms of cDNA synthesis to protect bacteria against viral infection. However, much of DRT family diversity remains ...
www.biorxiv.org
October 17, 2025 at 5:22 PM
1/10 Genome maintenance by telomerase is a fundamental process in nearly all eukaryotes. But where does it come from?
Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria.
www.biorxiv.org/content/10.1...
Today, we report the discovery of telomerase homologs in a family of antiviral RTs, revealing an unexpected evolutionary origin in bacteria.
www.biorxiv.org/content/10.1...
Reposted by Hugo Bisio
Our paper on chromosome segregation in the archaeon Sulfolobus Acidocaldarius has been published in PNAS! This has been a great collaboration with @joeparham19.bsky.social and the rest of @buzzbaum.bsky.social's team. Stay tuned for more to come!😉 @istaresearch.bsky.social
doi.org/10.1073/pnas...
doi.org/10.1073/pnas...
Temporal and spatial coordination of DNA segregation and cell division in an archaeon | PNAS
Cells must coordinate DNA segregation with cytokinesis to ensure that each daughter
cell inherits a complete genome. Here, we explore how DNA segre...
doi.org
October 16, 2025 at 8:53 AM
Our paper on chromosome segregation in the archaeon Sulfolobus Acidocaldarius has been published in PNAS! This has been a great collaboration with @joeparham19.bsky.social and the rest of @buzzbaum.bsky.social's team. Stay tuned for more to come!😉 @istaresearch.bsky.social
doi.org/10.1073/pnas...
doi.org/10.1073/pnas...