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jsross119.bsky.social
Joseph Ross
@jsross119.bsky.social
460 followers 300 following 79 posts

Primary care physician/health policy research @yaleschoolofmed.bsky.social; @ncspyale.bsky.social; healthy skeptic; @jama.com deputy editor; open science: YODAProject @yalecrrit.bsky.social @medrxivpreprint.bsky.social

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Economics 46%
Medicine 16%
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jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · 1d
Thanks @arnoldventures.bsky.social for supporting @yalecrrit.bsky.social - study builds on work nearly a decade ago published in @jama.com (jamanetwork.com/journals/jam...) - flagging for @alecgaffney.bsky.social @zacharybrennan.bsky.social @sarahkarlin-smith.bsky.social @lizzylawrence.bsky.social
Postmarket Safety Events Among Therapeutics Approved by the FDA
This study describes withdrawals, boxed warnings, and safety communications affecting pharmaceuticals and biologics approved by the US Food and Drug Administration between 2001 and 2010, and associati...
jamanetwork.com

Reposted by Stacie B. Dusetzina

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · 1d
Lots more detail in the paper (jamanetwork.com/journals/jam...), but our findings provide the first evaluation of FDAAA and its enhanced safety-related regulatory authorities, and its impact on drug safety and public health, and informs current PDUFA VII negotiations! @reshmagar.bsky.social (5/5)
Postmarket Drug Safety−Related Actions Before and After the FDA Amendments Act
This cross-sectional analysis assesses whether the US Food and Drug Administration Amendments Act was associated with differences in time to first postmarket drug safety−related action and whether the...
jamanetwork.com

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · 1d
... among therapeutics with postmarket safety-related actions within 5 years of approval, median time to first action was 1.3 years shorter post-FDAAA implementation, perhaps a consequence of FDAAA's conferring FDA new PMR authority and defined timelines for label changes (4/5)

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · 1d
Among these, FDA took postmarket safety-related actions for 23%, including actions within 5 years of approval for 21% approved pre-FDAAA and 14% approved post-FDAAA (p=.06). While FDAAA was not associated with differences in time to first postmarket safety-related action ... (3/5)

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · 1d
We wanted to understand whether FDAAA was associated with changes in FDA postmarket drug safety−related actions, and what characteristics were associated with a greater or lower likelihood of actions. To do this, we studied all 560 new drugs and biologics approved by FDA from 2001-2017 (2/5)

Reposted by Reshma Ramachandran

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · 1d
New paper from @yalecrrit.bsky.social out today in @jamainternalmed.com - The 2007 US Food and Drug Administration (FDA) Amendments Act (FDAAA) expanded the agency's safety-related regulatory authorities, including enhanced postmarketing safety surveillance and new clinical study requirements (1/5)

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · Sep 22
See recent articles in @jama.com, such as jamanetwork.com/journals/jam..., jamanetwork.com/journals/jam..., and jamanetwork.com/journals/jam... @lisamjarvis.bsky.social
Trends in the Proportion of US and International Medical Graduates at the County Level
This study assesses temporal trends in US medical graduates’ and international medical graduates’ relative contributions to the total physician workforce from 2010 to 2022, by rurality and across medi...
jamanetwork.com

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · Sep 22
Most early attention on the H-1B EO imposing a $100k fee is focused on the tech industry (i.e., good story by @joshwingrovebbg.bsky.social and Spencer Soper) www.bloomberg.com/news/article.... However, this policy will have a huge impact on healthcare delivery systems and research enterprise (1/2)
Trump Shapes Gilded Age of US Immigration With $100,000 H-1B Fee
President Donald Trump took his most extensive step yet toward overhauling the US legal migration system, with a pair of proclamations that explicitly favor the wealthiest of the world’s prospective e...
www.bloomberg.com

Reposted by Joseph S. Ross, Reshma Ramachandran

hollylynchez.bsky.social
Holly Fernandez Lynch @hollylynchez.bsky.social · Sep 20
Here's our new article reporting findings from stakeholder interviews in which we hoped to learn what it takes to successfully complete rigorous confirmatory studies after accelerated approval. Instead, we mostly heard willingness to trade rigor for feasibility. 1/
academic.oup.com/healthaffair...
Flexibility Over Rigor: Stakeholder Acceptance of the Limitations of Confirmatory Studies Following Accelerated Approval
Despite the importance of postmarketing requirements (PMRs) following accelerated approval and well-recognized shortcomings in their rigor and timeliness,
academic.oup.com

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · Sep 10
"Climate change is no longer a problem for our grandchildren but is inflicting profound economic and health damage right now.” @markgongloff.bsky.social
markgongloff.bsky.social Mark Gongloff @markgongloff.bsky.social · Sep 8
Climate change is an economic emergency, part 1000:

More than $1 trillion in US wages has been lost to wildfire smoke alone in the past 5 years. Gift link to my column for @opinion.bloomberg.com

www.bloomberg.com/opinion/arti...
$1 Trillion in American Wages Has Gone Up in Wildfire Smoke
The toxic haze is a nightmare for health and productivity.
www.bloomberg.com

Reposted by Joseph S. Ross

markgongloff.bsky.social
Mark Gongloff @markgongloff.bsky.social · Sep 8
Climate change is an economic emergency, part 1000:

More than $1 trillion in US wages has been lost to wildfire smoke alone in the past 5 years. Gift link to my column for @opinion.bloomberg.com

www.bloomberg.com/opinion/arti...
$1 Trillion in American Wages Has Gone Up in Wildfire Smoke
The toxic haze is a nightmare for health and productivity.
www.bloomberg.com

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · Sep 6
Kudos to @fda.gov leadership for following through on their efforts to promote transparency by posting CRLs for 2024 pending or withdrawn product applications. There is a lot that scientists, industry and clinicians can learn when FDA does not approve a product www.fiercebiotech.com/biotech/fda-...
FDA moves to publish drug rejection letters in real time, releases new batch including Replimune's high-profile snub
The FDA today announced a plan to p | The Food and Drug Administration today announced a plan to publicly release complete response letters at the same time they are issued to sponsoring companies, pa...
www.fiercebiotech.com

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · Sep 6
Great reporting on RFK "going wild" by sabotaging the @altcdc.altgov.info @dhruvkhullar.bsky.social www.newyorker.com/magazine/202...

Reposted by Shannon Vallor, Joseph S. Ross, Joe R. Feagin , and 10 more

petridishes.bsky.social
Alexandra Petri @petridishes.bsky.social · Sep 4
Florida Decided There Were Too Many Children
Florida Decided There Were Too Many Children
The state’s elimination of vaccine mandates is a courageous first step toward decluttering itself of any excess kids.
www.theatlantic.com

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · Sep 4
Great story by @annaedney.bsky.social ... reminds me of what happened with Essure, as patients complaints went unheeded for years
annaedney.bsky.social Anna Edney @annaedney.bsky.social · Sep 4
In my @bloomberg.com Big Take out today I explored how Hologic pushed a medical device on breast cancer patients despite hundreds of complaints, most of which stayed buried until now

Reposted by Joseph S. Ross

madhupai.bsky.social
Madhu Pai, MD, PhD @madhupai.bsky.social · Sep 4
Florida Made a Vaccine Mistake. Now, It’s Everyone’s Problem.

Agree with @lisamjarvis.bsky.social, viruses don’t give a damn for state lines

www.bloomberg.com/opinion/arti...
Florida Made a Vaccine Mistake. Now, It’s Everyone’s Problem.
State efforts to protect access to shots are welcome, but they can’t compensate for others’ anti-science policies and a dysfunctional CDC.
www.bloomberg.com

Reposted by Joseph S. Ross, Daniel Aaron

annaedney.bsky.social
Anna Edney @annaedney.bsky.social · Sep 4
In my @bloomberg.com Big Take out today I explored how Hologic pushed a medical device on breast cancer patients despite hundreds of complaints, most of which stayed buried until now

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · Sep 3
"The American scientific enterprise is being unravelled before our eyes—research grants are being cut off, satellites disconnected, reports cooked up [by] particular industries and ideologies ... but in the end, the truth will [win] out." @billmckibben.bsky.social www.newyorker.com/news/the-led...
Trump’s Department of Energy Gets Scienced
International climate experts have extensively debunked the D.O.E.’s recent report, but will science win out?
www.newyorker.com

Reposted by Joseph S. Ross

peerreviewcongress.bsky.social
Peer Review Congress #PRC10 @peerreviewcongress.bsky.social · Sep 1
"In a world accustomed to receiving real-time information, the process of publishing medical research remains trapped in a system designed for a slower era,” per @jsross119.bsky.social & colleagues from @utoronto.ca Med in @annalsofim.bsky.social
www.acpjournals.org/doi/10.7326/...
#peerreview
On a Slow Boat to Publication: Rethinking How We Disseminate Medical Research | Annals of Internal Medicine
www.acpjournals.org

Reposted by Joseph S. Ross

thewonkologist.bsky.social
Aaron Mitchell @thewonkologist.bsky.social · Aug 27
“Physicians receiving payments were more likely to prescribe the company's drugs, with a stronger association for payments that were larger, sustained and recent.”

New work on bribes to Rx multiple sclerosis drugs by Sayed, @reshmagar.bsky.social @jsross119.bsky.social
Industry payments to US neurologists related to multiple sclerosis drugs and prescribing (2015-2019): a retrospective cohort study - PubMed
Nearly 80% of neurologists prescribing MS drugs received at least one industry payment, with higher volume prescribers being more likely to receive payments. Physicians receiving payments were more li...
pubmed.ncbi.nlm.nih.gov

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · Aug 19
Amazing data visualization illustrating how Grier family manipulated science to ‘prove’ vaccines cause autism. Key take-home: "those who claim to champion people with autism are denying them real research while undermining one of public health’s greatest achievements" www.nytimes.com/interactive/...
Opinion | The Playbook Used to ‘Prove’ Vaccines Cause Autism
Data can easily be manipulated to show a causation that doesn’t exist.
www.nytimes.com

Reposted by Joseph S. Ross

craigtimes.bsky.social
Craig Pittman @craigtimes.bsky.social · Aug 4
The EPA's disastrous plan to end the regulation of greenhouse gases & just let climate change run rampant. www.newyorker.com/news/the-led... via @elizkolbert.bsky.social
The E.P.A.’s Disastrous Plan to End the Regulation of Greenhouse Gases
With a new proposal, the Trump Administration, which has already laid waste to dozens of programs aimed at limiting climate change, has managed to outdo itself.
www.newyorker.com

Reposted by Joseph S. Ross

juddlegum.bsky.social
Judd Legum @juddlegum.bsky.social · Aug 4
1. On February 24, Extremity Care LLC, a company that sells very expensive bandages made from placentas, donated $5 MILLION TO TRUMP'S SUPER PAC

Days later, Trump froze a pending rule that would BAR MEDICARE FROM COVERING EXTREMITY CARE'S PRODUCTS, which are overpriced & not backed by science.
Days after $5 million donation to MAGA Inc., Trump freezes Medicare waste crackdown
Trump pledged to root out "waste, fraud and abuse." Then a big contribution to his Super PAC came in.
popular.info

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · Aug 3
"The esteemed climate scientist Michael Mann said the report was akin to the result he would expect “if you took a chatbot and you trained it on the top 10 fossil fuel industry-funded climate denier websites”."
www.theguardian.com/us-news/2025...
Scientists slam Trump administration climate report as a ‘farce’ full of misinformation
Experts say the report being used to justify the mass rollback of climate regulations has many claims based on long-debunked research
www.theguardian.com

Reposted by Joseph S. Ross, Du Toit, Jesse H. Kroll , and 1 more

hausfath.bsky.social
Zeke Hausfather @hausfath.bsky.social · Aug 3
I have a new post over at The Climate Brink on how the recent DOE report on climate science and the EPA's proposed overturning of the endangerment finding used and misused my research: www.theclimatebrink....
How the DOE and EPA used and misused my research
Elevating contrarian views while burying the actual science
www.theclimatebrink.com

jsross119.bsky.social
Joseph Ross @jsross119.bsky.social · Aug 1
"If the US is no longer the world’s technoscientific superpower, it will almost certainly suffer for the change. America’s technology sector might lose its creativity. But science itself, in the global sense, will be fine. The deep human curiosities that drive it do not belong to any nation-state."
theatlantic.com The Atlantic @theatlantic.com · Jul 31
The rapid decline of American science has few precedents in history, argues @rossandersen.bsky.social. We are witnessing an unparalleled act of self-sabotage:
How Scientific Empires End
And what it means for America
bit.ly

Reposted by Joseph S. Ross

theatlantic.com
The Atlantic @theatlantic.com · Jul 31
The rapid decline of American science has few precedents in history, argues @rossandersen.bsky.social. We are witnessing an unparalleled act of self-sabotage:
How Scientific Empires End
And what it means for America
bit.ly

Reposted by Joseph S. Ross, Linda J. Skitka, Caroline Fohlin

nstenhouse.bsky.social
Neil Stenhouse @nstenhouse.bsky.social · Jun 29
“ICE gets a bigger budget than the Marine Corps” is a simple fact that should be communicated very widely because it clearly expresses how crazy and radical this is
dburbach.bsky.social David Burbach 🇺🇸🌹 @dburbach.bsky.social · Jun 29
With this budget, ICE alone would have nearly as large a detention operation as all 50 states' prison systems combined. Bigger budget than the Marine Corps. Police-state levels of spending
reichlinmelnick.bsky.social Aaron Reichlin-Melnick @reichlinmelnick.bsky.social · Jun 28
If the GOP reconciliation bill passes, ICE gets through FY2029:

- $45 billion for detention, on top of the current annual budget of $3.4 billion
- $14.4 billion for transportation and removal, on top of the current annual budget of $750 million
- $8 billion for hiring/retention
- Billions more.

Reposted by Joseph S. Ross

zacharybrennan.bsky.social
Zachary Brennan @zacharybrennan.bsky.social · Apr 1
Breaking: Firings sweep across FDA, gutting leadership and whole offices endpts.com/firings-swee...
Breaking: Firings sweep across FDA, gutting leadership and whole offices
Mass firings and forced resignations swept through the FDA on Tuesday, as part of thousands of planned job cuts at federal health agencies being implemented by the Trump administration.
endpts.com

Reposted by Joseph S. Ross

jama.com
JAMA @jama.com · Apr 3
Deportations and immigration restrictions could impact the US health care system by removing skilled noncitizen workers, leading to staff shortages and compromised patient care. https://ja.ma/4ci0NpS
Deporting Immigrants May Further Shrink the Health Care Workforce
This study explores the potential for health care staffing shortages in the US by estimating the number of immigrants employed in health care who could be affected by deportation or immigration restrictions.
ja.ma