James Pirruccello 🌉
@jamespirruccello.com
AI slop (except one) enjoyer
What did they know? (Hackers, 1995)
January 20, 2026 at 4:13 AM
What did they know? (Hackers, 1995)
Neither a wordcel nor a rotator be.
January 19, 2026 at 7:15 PM
Neither a wordcel nor a rotator be.
Artificial Intelligence Gore's Internet
January 19, 2026 at 5:39 AM
Artificial Intelligence Gore's Internet
impeachably weird
January 19, 2026 at 5:27 AM
impeachably weird
MacOS really said "No, you will not be typing Erdős".
January 18, 2026 at 7:11 AM
MacOS really said "No, you will not be typing Erdős".
PNAS paper idea: "Gas Town for semantic segmentation"
Who's writing this?
Who's writing this?
January 18, 2026 at 1:44 AM
PNAS paper idea: "Gas Town for semantic segmentation"
Who's writing this?
Who's writing this?
The NASA / Crew Dragon re-entry was easily visible to the eye to the west of San Francisco.
January 15, 2026 at 8:37 AM
The NASA / Crew Dragon re-entry was easily visible to the eye to the west of San Francisco.
Your Claude is dead 🎶
And no one cares 🎶
If there is a shell 🎶
I’ll C you there 🎶
And no one cares 🎶
If there is a shell 🎶
I’ll C you there 🎶
January 15, 2026 at 7:37 AM
Your Claude is dead 🎶
And no one cares 🎶
If there is a shell 🎶
I’ll C you there 🎶
And no one cares 🎶
If there is a shell 🎶
I’ll C you there 🎶
Lovely editorial on the forthcoming oral PCSK9 inhibitor enlicitide from Michelle O'Donoghue and Nick Marston at the Brigham:
💬 Editorial: The CORALreef HeFH trial demonstrated that oral enlicitide achieves robust, sustained reductions in LDL-C and other atherogenic lipids in patients with heterozygous familial hypercholesterolemia already receiving statin therapy.
ja.ma/4sBc3VU
ja.ma/4sBc3VU
January 13, 2026 at 5:25 PM
Lovely editorial on the forthcoming oral PCSK9 inhibitor enlicitide from Michelle O'Donoghue and Nick Marston at the Brigham:
What is every cardiologist's favorite NYC borough?
Yes that's right, Statin Island.
Yes that's right, Statin Island.
January 13, 2026 at 4:42 PM
What is every cardiologist's favorite NYC borough?
Yes that's right, Statin Island.
Yes that's right, Statin Island.
You say "perfidy," I say "according to Curtis James Jackson III".
oh so now all of a sudden everyone’s an expert in “perfidy”
January 13, 2026 at 1:57 AM
You say "perfidy," I say "according to Curtis James Jackson III".
Sunset Dunes was popping off @sunsetdunes.org
January 11, 2026 at 10:13 PM
Sunset Dunes was popping off @sunsetdunes.org
@frankfukuyama.bsky.social can we please go back to history being over? tysm
January 11, 2026 at 3:09 AM
@frankfukuyama.bsky.social can we please go back to history being over? tysm
Remember when President Bill Clinton played the saxophone?
January 9, 2026 at 5:30 AM
Remember when President Bill Clinton played the saxophone?
Imagine how big Buc-ee’s must look on a Mercator map.
January 6, 2026 at 8:46 PM
Imagine how big Buc-ee’s must look on a Mercator map.
Oh, you're a biologist? Then explain what the Vault does.
January 5, 2026 at 5:43 PM
Oh, you're a biologist? Then explain what the Vault does.
"A group of people" are going to run it? Which group?
January 3, 2026 at 5:17 PM
"A group of people" are going to run it? Which group?
Stop trying to make 'DONROE' happen.
January 3, 2026 at 4:57 PM
Stop trying to make 'DONROE' happen.
As long as there are no follow-up questions, crime is down 500%.
January 3, 2026 at 4:51 PM
As long as there are no follow-up questions, crime is down 500%.
Looking back to the Jimmy Carter days? Sure, why not. Let's remember the Herbert Hoover days. Fondly thinking about the Teddy Roosevelt days.
January 3, 2026 at 4:43 PM
Looking back to the Jimmy Carter days? Sure, why not. Let's remember the Herbert Hoover days. Fondly thinking about the Teddy Roosevelt days.
The "250" looks very bad?
January 1, 2026 at 4:00 AM
The "250" looks very bad?
As perceived in my timeline
December 31, 2025 at 5:42 PM
As perceived in my timeline