Georg Otto
gwotto.bsky.social
Georg Otto
@gwotto.bsky.social
Active biologist, bioinformatician and researcher. Retired caballarius saint. Severely affected by mental tsundoku.
Reposted by Georg Otto
Main take-away so far from very interesting presser on #Marburg outbreak in Rwanda: Health minister Sabin Nsanzimana says all cases are linked to known infection chains. The outbreak is one major cluster with three branches.
October 20, 2024 at 12:46 PM
Reposted by Georg Otto
Wow, the Guardian journalists who just yesterday published about the network of race scientists getting funding from tech CEOs just broke another story that this group has accessed UK Biobank data without authorization. This is seriously bad for the integrity of science & a massive failure by UKBB
‘Race science’ group say they accessed sensitive UK health data
Exclusive: Fringe network recorded boasting of securing data from UK Biobank trove donated by 500,000 volunteers
www.theguardian.com
October 17, 2024 at 3:40 PM
Reposted by Georg Otto
...Without that light of evolution, biology becomes a pile of sundry facts: some of them interesting or curious but making no meaningful picture as a whole."
- Theodosius Dobzhansky.
October 17, 2024 at 12:57 PM
Reposted by Georg Otto
In the end, I don't especially care if you accept evolution, or if it clashes with your religious dogma.

Teaching it in public schools is the only way to prepare students with the framework they will need for any course in biology, ecology, medicine or genetics.
October 17, 2024 at 12:55 PM
Reposted by Georg Otto
After getting duckpilled and writing yesterday about DuckDB and duckplyr as a faster alternative to base R and dplyr, today I follow that up with a look at parquet (nanoparquet) as a better and faster alternative to CSV (readr) blog.stephenturner.us/p/use-nanopa... #rstats
Use nanoparquet instead of readr/CSV
Parquet is interoperable between Python and R, fast to read+write, works well with databases, and stores complex data types (e.g., tibble listcols). Use it instead of CSV. Many pros, few (no?) cons.
blog.stephenturner.us
October 8, 2024 at 11:56 AM
Reposted by Georg Otto
#Marburg outbreak in Rwanda is now up to 41 cases incl. 12 deaths and 5 patients that have recovered according to the Ministry of Health
October 4, 2024 at 10:41 PM
October 4, 2024 at 6:54 AM
Reposted by Georg Otto
Holy YIKES a redshift of 14.2 is high. That's a helluva long way off. Here's my explainer of the number (from a different galaxy observation):

badastronomy.beehiiv.com/p/jwst-bags-...

🔭🧪
October 3, 2024 at 6:53 PM
Reposted by Georg Otto
This is *and I can’t emphasise this enough* a brilliant podcast episode
NEW EPISODE OUT NOW!

In today’s episode David and @shannonvallor.bsky.social discuss Isaac Asimov’s 1955 short story ‘Franchise’, which imagines the American presidential election of 2008 as decided by one voter and a giant computer.

Find us at...🎧 ppfideas.com

shows.acast.com/pastpresentf...
Thinking About Thinking Machines: Isaac Asimov’s ‘Franchise’ | Past Present Future
The History of Ideas Podcast
shows.acast.com
September 26, 2024 at 11:38 AM
Reposted by Georg Otto
As much as we all love our deliciously horrible killer viruses getting ready for the next pandemic, I think the creeping threat of less and less treatable common bacterial infections is actually much worse.
#episky
🧪
Anti-microbial resistance to antibiotics (AMR) is one of our biggest threats now. This article highlights the risk + prevalence of contaminated water, the lack of adequate diagnostic testing risking inappropriate antibiotics being used and need for action globally 🧪
‘Drug-resistant typhoid is the final warning sign’: disease spreads in Pakistan as antibiotics fail
As world leaders discuss the battle against superbugs in New York, Pakistan’s children are suffering on the frontline
www.theguardian.com
September 24, 2024 at 9:18 AM
Reposted by Georg Otto
If you hate statistics like I do, then you'll love my free lectures. Putting science before statistics, 20 lectures from basics of inference & causal modeling to multilevel models & dynamic state space models. It's all free, made with love and sympathy. 🧪 #stats www.youtube.com/playlist?lis...
September 19, 2024 at 10:56 AM
Reposted by Georg Otto
some fancy shrimps got a big idea and crawled outta the ocean like 500 million years ago and now we got these jabronis
September 18, 2024 at 7:41 PM
Reposted by Georg Otto
Engineered E coli determine if a number is prime, if a letter is a vowel, and the maximum number of pieces of pie that can be made for a given number of cuts. "Prints" answers by expressing fluorescent proteins https://www.nature.com/articles/s41589-024-01711-4
September 18, 2024 at 8:00 PM
Reposted by Georg Otto
It's Ig Nobel season again! This one's remarkably depressing! 😀

[Longevity data.. set everyone’s pension rate - $$ trillions. If data are junk, so are [pension] projections. It also means we’re allocating money wrong. Insurance premiums are based on this stuff.]

theconversation.com/the-data-on-...
‘The data on extreme human ageing is rotten from the inside out’ – Ig Nobel winner Saul Justin Newman
Saul Newman’s research suggests that we’re completely mistaken about how long humans live for.
theconversation.com
September 15, 2024 at 7:05 AM
Reposted by Georg Otto
Dave Grohl is back in the headlines, and you all know what that means: re-upping the "Foo Fighters indirectly caused hundreds of thousands of deaths through medical misinformation" thread.
I don't think I've ever talked on Bluesky about why I hate the Foo Fighters and Dave Grohl.

Don't read any further unless you're prepared for uncomfortable truths about the "Nicest Guy in Rock", and his very substantial body count & subsequent cover-up.
September 10, 2024 at 9:37 PM
Reposted by Georg Otto
🧪 Nature reports on #Pathoplexus, a new initiative that incentivizes sharing viral genome data in real-time 🦠🧬. www.nature.com/articles/d41...
New virus-genome website seeks to make sharing sequences easy and fair
The Pathoplexus database has sequences from Ebola, West Nile virus and another dangerous pathogen. The Pathoplexus database has sequences from Ebola, West Nile virus and another dangerous pathogen.
www.nature.com
September 10, 2024 at 1:25 AM
Six novels about India, perhaps the world’s most interesting place
www.economist.com/the-economis...
from The Economist
August 28, 2024 at 6:36 PM
Al rescate de dos millones de topónimos a través de una ‘app’ para salvar la memoria de los abuelos - elpais.com/espana/galic...
Al rescate de dos millones de topónimos a través de una ‘app’ para salvar la memoria de los abuelos
La Real Academia Galega impulsa la mayor recogida de nombres de lugar acometida en Europa en una comunidad, Galicia, que suma más de un tercio de todas las entidades de población de España
elpais.com
August 27, 2024 at 11:22 PM
Reposted by Georg Otto
I’ve read a lot of stuff about #mpox already that is wrong or at least confused. And it’s not that surprising. The situation is pretty complicated and confusing. I tried to disentangle a few things for Science here (thread to come later):

www.science.org/content/arti...
Confused about the mpox outbreaks? Here’s what’s spreading, where, and why
With three virus variants on the move in different populations, “it keeps getting more complicated by the day”
www.science.org
August 25, 2024 at 6:27 AM
Reposted by Georg Otto
I really firmly think that even if you don't want to read all of "Moby Dick" you can have so much fun just reading the first chapter
August 25, 2024 at 11:08 PM
Reposted by Georg Otto
Paper describing the difficulties of establishing genetic causation in studies of human behavior. @arbelharpak.bsky.social @jedidiahcarlson.com www.biorxiv.org/content/10.1...
Confounding Fuels Misinterpretation in Human Genetics
bioRxiv - the preprint server for biology, operated by Cold Spring Harbor Laboratory, a research and educational institution
www.biorxiv.org
August 23, 2024 at 8:32 PM
Reposted by Georg Otto
My first post. Wednesday Morning's great Saturn occultation by the Moon.
August 24, 2024 at 7:13 AM
Reposted by Georg Otto
As a sparkly citizen of the world, you must defend yourself against research. You need it, but you can't assume peer review works. But a little knowledge goes a long way. Here is a 15 min video of me explaining one of the most common fallacies, "TABLE 2" #stats: youtu.be/uanZZLlzKHw?...
Statistical Rethinking 2023 - 06 - Good & Bad Controls
YouTube video by Richard McElreath
youtu.be
August 24, 2024 at 10:46 AM
Reposted by Georg Otto
Largest animal genome ever sequenced: 91 Gb. 18 of 19 chromosomes are each individually larger than the entire 3 Gb human genome.

The genomes of all lungfish inform on genome expansion and tetrapod evolution https://www.nature.com/articles/s41586-024-07830-1 (free: https://rdcu.be/dRE64)
August 22, 2024 at 6:30 PM