Colleen E. Clancy PhD
clancyatheart.bsky.social
Colleen E. Clancy PhD
@clancyatheart.bsky.social
Colleen E. Clancy, Ph.D.
Editor-in-Chief: The Journal of Precision Medicine, Professor of Physiology and Director of Precision Medicine at UC Davis
Reposted by Colleen E. Clancy PhD
In @jgp.org, Jenna Lin and Baron Chanda compare different gating models to account for the diverse gating phenotypes observed across the cyclic nucleotide-binding domain (CNBD) family, including those arising from targeted mutations and chimeragenesis. rupress.org/jgp/article/...

#IonChannels
December 11, 2025 at 6:33 PM
Reposted by Colleen E. Clancy PhD
Great way to start the final month of the year with the publication of this collaborative work on how dopamine regulates L-type channels in #neurons.

www.science.org/doi/10.1126/...

And we got the cover!!! @ucdavis.bsky.social, @ucdavishealth.bsky.social
Stimulation of Ca2+ channel CaV1.2 activity by dopamine signaling augments spatial working memory
Dopamine-induced phosphorylation of an L-type Ca2+ channel supports working memory in mice.
www.science.org
December 9, 2025 at 11:32 PM
Congratulations!!!!!
December 10, 2025 at 12:46 AM
We are anticipating a truly exceptional collection of studies based on current commitments! Please send us your study on NAMs - we would love to have a chance to review it!
Colleagues, we are excited to receive your papers on New Approach Methodologies! Reach out to me if you have a presubmission question!
📣 CALL FOR PAPERS📣

Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎

Submit by 28 February 2026 ⏰

🔗 For topics and more information:

www.sciencedirect.com/special-issu...
December 10, 2025 at 12:42 AM
Reposted by Colleen E. Clancy PhD
📣CALL FOR PAPERS📣
For our "Contemporary antioxidant interventions: transforming the study of redox #biology in health and disease" #SpecialIssue! This special issue will provide insights into the #redox mechanisms underpinning health and disease!

🎓 buff.ly/LGKQ90r
December 3, 2025 at 5:02 PM
Colleagues, we are excited to receive your papers on New Approach Methodologies! Reach out to me if you have a presubmission question!
📣 CALL FOR PAPERS📣

Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎

Submit by 28 February 2026 ⏰

🔗 For topics and more information:

www.sciencedirect.com/special-issu...
October 20, 2025 at 7:40 PM
Reposted by Colleen E. Clancy PhD
📣 CALL FOR PAPERS📣

Examining New Approach Methodologies #NAMs in #precisionmedicine 💉🔎

Submit by 28 February 2026 ⏰

🔗 For topics and more information:

www.sciencedirect.com/special-issu...
October 6, 2025 at 2:42 PM
Reposted by Colleen E. Clancy PhD
Jehad Feras AlSamhori of The University of Jordan et al. examine the role of #ChatGPT in improving orthopedic patient education in low-resource settings across various #orthopedic specialties ✍️ 🥼

🔗 📜 Read the #Review here: www.jprecisionmedicine.org/article/S305...
October 13, 2025 at 12:00 PM
Reposted by Colleen E. Clancy PhD
In this recent #Review, Umama Shahid of Monash University Malaysia discusses the mechanistic insights, multi-omics integration, and translational horizons of #microbiome-guided precision medicine ✍️ 💉

🔗 Read the article here:
www.jprecisionmedicine.org/article/S305...
October 14, 2025 at 2:02 PM
Reposted by Colleen E. Clancy PhD
🚨CALL FOR PAPERS🚨
For our "Integrative physiological considerations of the human vasculature system" #SpecialIssue, which will showcase further insights into vascular haemodynamics and multi-organ diseases, as well as the technology used to monitor and treat cardiovascular disease

🔗 buff.ly/HN7wlPr
September 17, 2025 at 4:10 PM
Reposted by Colleen E. Clancy PhD
Turning sunlight into fuel [via Uni of Basel] 🧪⚗️🪴🌞⛽🔋

"a plant-inspired molecule that can store four charges using sunlight, a key step toward artificial photosynthesis"

www.nature.com/articles/s41...

#artificial #photosynthesis #sunlight #fuel #energy #environment #friendly
Photoinduced double charge accumulation in a molecular compound - Nature Chemistry
The photoinduced accumulation of redox equivalents is a challenging requirement for artificial photosynthesis. Now a molecule has been developed in which the sequential absorption of photons results i...
www.nature.com
August 26, 2025 at 6:31 PM
Please join us for the upcoming NHLBI workshop on digital twins!
Please register and spread the word! www.nhlbi.nih.gov/events/2025/...
Digital Twins in Heart, Lung, Blood, and Sleep Research Virtual Workshop
The Digital Twins in Heart, Lung, Blood, and Sleep Research Virtual Workshop will take place virtually on September 25–26, 2025.
www.nhlbi.nih.gov
August 22, 2025 at 7:59 PM
Reposted by Colleen E. Clancy PhD
"If the U.S. is no longer the world’s technoscientific superpower, it will almost certainly suffer for the change. America’s technology sector might lose its creativity. But science itself, in the global sense, will be fine. The deep human curiosities that drive it do not belong to any nation-state"
Every Scientific Empire Comes to an End
America’s run as the premier techno-superpower may be over.
www.theatlantic.com
August 2, 2025 at 9:48 PM
Reposted by Colleen E. Clancy PhD
Mind the midpoints: Rethinking variability in cardiac INa. Commentary from @clancyatheart.bsky.social @ucd-physiology.bsky.social highlighting the new study from @michaelclerx.com and colleagues (rupress.org/jgp/article/...): rupress.org/jgp/article/...
July 23, 2025 at 6:15 PM
Reposted by Colleen E. Clancy PhD
We traveled to DC to talk to Congressional Staffers about the impact of NIH and NIBIB funding. It enables us to develop synthetic biology tools to advance cell & genetic medicines for patients in need. REPOST to deliver the message that SCIENCE saves lives & makes America GREAT!
July 21, 2025 at 12:16 PM
Reposted by Colleen E. Clancy PhD
Hope you like it!

Thanks to the very helpful reviewers and editor.
And an extra special thank you to @clancyatheart.bsky.social who wrote a very thoughtful commentary here: doi.org/10.1085/jgp....
Mind the midpoints: Rethinking variability in cardiac INa | Journal of General Physiology | Rockefeller University Press
The comprehensive meta-analysis from Clerx and coauthors challenges long-standing assumptions about data interpretation, data comparison, and electrophysio
doi.org
July 16, 2025 at 4:55 PM
Reposted by Colleen E. Clancy PhD
@clancyatheart.bsky.social highlights the comprehensive meta-analysis in @jgp.org from Clerx et al. (rupress.org/jgp/article/... ) that challenges long-standing assumptions about data interpretation, data comparison, and electrophysiological data used to develop models. rupress.org/jgp/article/...
July 16, 2025 at 7:30 PM
So excited to share our study just published in eLife, “Harnessing AlphaFold to reveal hERG channel conformational state secrets” doi.org/10.7554/eLif...
Harnessing AlphaFold to reveal hERG channel conformational state secrets
Customized AlphaFold-based modeling of distinct functional states of the hERG channel, a major drug anti-target, significantly improves drug affinity predictions, enhancing cardiac safety screening fo...
doi.org
July 14, 2025 at 11:21 PM
So thrilling to share this game changing study from Dr. Patrick Ott group at Dana Farber. Dr. Ott is one of our esteemed senior editors at the Journal of Precision Medicine: Health and Disease! www.sciencedirect.com/science/arti...
A multi-adjuvant personal neoantigen vaccine generates potent immunity in melanoma
Personalized neoantigen-targeting vaccines have demonstrated great promise; however, improved immunogenicity is still needed. Since antigen availabili…
www.sciencedirect.com
July 10, 2025 at 4:50 PM
Reposted by Colleen E. Clancy PhD
Hello microscopy and imaging experts and enthusiasts!
We are looking for a staff scientist to join us here in Geneva to work on microscopy and image analysis projects! See the link for the job announcement (in French and in English).

Please apply and/or repost!

jobs.unige.ch/www/wd_porta...
July 7, 2025 at 2:05 PM
Reposted by Colleen E. Clancy PhD
Please see our open call for the upcoming special issue! We look forward to your submissions!
📣 CALL FOR PAPERS 📣

For our first #SpecialIssue edited by @vyy-sf.bsky.social
focusing on:

💉Precision medicine
🏠Structural biology
🧬Protein structure
🔄Protein dynamics
🖊️Biomarkers

🔗For full list of topics👇

www.sciencedirect.com/special-issu...

#proteinstructure #precisionmedicine
June 11, 2025 at 4:16 PM
Reposted by Colleen E. Clancy PhD
Carla Clemente of STAB VIDA et al. examined the analytical performance & clinical utility of a new LAMP-based portable system for the detection of somatic variants in non-small cell lung cancer patients 🫁🧬

Read the #Research article here: www.sciencedirect.com/science/arti...
June 18, 2025 at 12:12 PM
Reposted by Colleen E. Clancy PhD
Nominations for our Inaugural Review Prize are open!

🏆 The winner will receive £1000, and publish a Review Article in our journal.

📆 Nominations are open until 31 July 2025.

📜 Find out more about how to apply and submit your proposal: buff.ly/4cc9Asn
July 3, 2025 at 3:05 PM
A thrilling achievement! We are so proud of you @doctheagrif.bsky.social and @elisazhang.bsky.social!!!!
Congratulations to all the amazing scientists named 2025 Freeman Hrabowski Scholars by HHMI. We’re immensely honored to have two #PMB faculty members, @doctheagrif.bsky.social and @elisazhang.bsky.social , among this inspiring group. An incredible and well-deserved achievement! @ucdavis.bsky.social
The 2025 Freeman Hrabowski Scholars | HHMI
Freeman Hrabowski Scholars are outstanding early career faculty who have the potential to become leaders in their research fields.
www.hhmi.org
June 19, 2025 at 7:12 PM
Reposted by Colleen E. Clancy PhD
New book! 📖 #PMB’s Professor Aldrin Gomes and his lab explore how ibuprofen affects the body. An insightful look at this common painkiller in action. www.ucdavis.edu/news/new-boo...
New Book Details the Good, Bad and Unexpected of Ibuprofen
What you don’t know about ibuprofen, one of the world’s most popular painkillers, could well fill a book — and that book has just been published, authored by Professor Aldrin Gomes and 36 of his curre...
www.ucdavis.edu
June 4, 2025 at 8:22 PM