Carl M
@camon345.bsky.social
Biomedical scientist. Care about the future of humanity and strongly dislike greed. Living simply.
Reposted by Carl M
'A shutdown of the AMOC “cannot be considered a low likelihood risk anymore in view of the evolving science over the past years,” said @rahmstorf.bsky.social , a physical oceanographer and climatologist who has studied the AMOC at @pik-potsdam.bsky.social '
A crucial system of ocean currents may be on course to collapse. This country just declared it a national security threat | CNN
Without warm currents from the South Atlantic, Iceland would be much icier and stormier. Now, those currents are at risk of collapse and the country is preparing for this “existential threat.”
edition.cnn.com
November 17, 2025 at 10:18 AM
'A shutdown of the AMOC “cannot be considered a low likelihood risk anymore in view of the evolving science over the past years,” said @rahmstorf.bsky.social , a physical oceanographer and climatologist who has studied the AMOC at @pik-potsdam.bsky.social '
Reposted by Carl M
“changes in statistical significance are often not themselves statistically significant. … even large changes in significance levels can correspond to small, nonsignificant changes in the underlying quantities.”
www.tandfonline.com/doi/abs/10.1...
#Statistics
www.tandfonline.com/doi/abs/10.1...
#Statistics
The Difference Between “Significant” and “Not Significant” is not Itself Statistically Significant
It is common to summarize statistical comparisons by declarations of statistical significance or nonsignificance. Here we discuss one problem with such declarations, namely that changes in statisti...
www.tandfonline.com
November 9, 2025 at 12:39 PM
“changes in statistical significance are often not themselves statistically significant. … even large changes in significance levels can correspond to small, nonsignificant changes in the underlying quantities.”
www.tandfonline.com/doi/abs/10.1...
#Statistics
www.tandfonline.com/doi/abs/10.1...
#Statistics
Reposted by Carl M
100 Python Projects — From Beginner to Expert
pythonclcoding.gumroad.com/l/100PythonP...
pythonclcoding.gumroad.com/l/100PythonP...
November 8, 2025 at 6:00 PM
100 Python Projects — From Beginner to Expert
pythonclcoding.gumroad.com/l/100PythonP...
pythonclcoding.gumroad.com/l/100PythonP...
Reposted by Carl M
Reposted by Carl M
Australia Institute research shows Australia gives more than half the gas we export away for free!
Former QLD Premier Steven Miles showed what can happen when our governments tax fossil fuels properly.
@stevenjmiles.bsky.social #auspol @thepointau.bsky.social
Former QLD Premier Steven Miles showed what can happen when our governments tax fossil fuels properly.
@stevenjmiles.bsky.social #auspol @thepointau.bsky.social
October 30, 2025 at 7:07 AM
Australia Institute research shows Australia gives more than half the gas we export away for free!
Former QLD Premier Steven Miles showed what can happen when our governments tax fossil fuels properly.
@stevenjmiles.bsky.social #auspol @thepointau.bsky.social
Former QLD Premier Steven Miles showed what can happen when our governments tax fossil fuels properly.
@stevenjmiles.bsky.social #auspol @thepointau.bsky.social
Reposted by Carl M
Breaking News!
Code UFB!!!
October 25th, 2025 was the hottest on record for the date since records began in 1940, making it likely the hottest October 25th in the last 120,000 years.
More records are forecast to be set over the next week. Stay tuned.
Code UFB!!!
October 25th, 2025 was the hottest on record for the date since records began in 1940, making it likely the hottest October 25th in the last 120,000 years.
More records are forecast to be set over the next week. Stay tuned.
October 27, 2025 at 12:19 PM
Breaking News!
Code UFB!!!
October 25th, 2025 was the hottest on record for the date since records began in 1940, making it likely the hottest October 25th in the last 120,000 years.
More records are forecast to be set over the next week. Stay tuned.
Code UFB!!!
October 25th, 2025 was the hottest on record for the date since records began in 1940, making it likely the hottest October 25th in the last 120,000 years.
More records are forecast to be set over the next week. Stay tuned.
Reposted by Carl M
🌀 💪📈
Category 5 Hurricane Melissa rapidly intensificatied with the power of about 500 TW (terawatt, 500*10¹² joules per second).
For comparison, that's 25 times humanity's average global energy use of 20 TW.
Earth's Energy Imbalance is about +700 TW 🤯
Category 5 Hurricane Melissa rapidly intensificatied with the power of about 500 TW (terawatt, 500*10¹² joules per second).
For comparison, that's 25 times humanity's average global energy use of 20 TW.
Earth's Energy Imbalance is about +700 TW 🤯
October 27, 2025 at 10:35 AM
🌀 💪📈
Category 5 Hurricane Melissa rapidly intensificatied with the power of about 500 TW (terawatt, 500*10¹² joules per second).
For comparison, that's 25 times humanity's average global energy use of 20 TW.
Earth's Energy Imbalance is about +700 TW 🤯
Category 5 Hurricane Melissa rapidly intensificatied with the power of about 500 TW (terawatt, 500*10¹² joules per second).
For comparison, that's 25 times humanity's average global energy use of 20 TW.
Earth's Energy Imbalance is about +700 TW 🤯
Reposted by Carl M
Watch the full discussion with Dr Sue Wareham OAM, alongside Dr Mohammed Mustafa and Professor Fiona Stanley AC ⤵️
australiainstitute.org.au/event/delive...
australiainstitute.org.au/event/delive...
Delivering Healthcare in Gaza
The world has been witness to the devastating toll of Israel’s genocide in Gaza. Join three healthcare professionals for a discussion on the medical and ethical dilemmas faced by those providing medic...
australiainstitute.org.au
October 24, 2025 at 3:54 AM
Watch the full discussion with Dr Sue Wareham OAM, alongside Dr Mohammed Mustafa and Professor Fiona Stanley AC ⤵️
australiainstitute.org.au/event/delive...
australiainstitute.org.au/event/delive...
Reposted by Carl M
'mRNA vaccines seem to boost the effectiveness of an immune therapy for skin and lung cancer.' @maxkozlov.bsky.social @nature.com
'COVID-19 mRNA vaccine acts like a siren and activates the immune system throughout the body - programming a response to kill the cancer.'
www.nature.com/articles/d41...
'COVID-19 mRNA vaccine acts like a siren and activates the immune system throughout the body - programming a response to kill the cancer.'
www.nature.com/articles/d41...
People with some cancers live longer after a COVID vaccine
mRNA vaccines seem to boost the effectiveness of an immune therapy for skin and lung cancer ― in an unexpected way.
www.nature.com
October 23, 2025 at 1:48 PM
'mRNA vaccines seem to boost the effectiveness of an immune therapy for skin and lung cancer.' @maxkozlov.bsky.social @nature.com
'COVID-19 mRNA vaccine acts like a siren and activates the immune system throughout the body - programming a response to kill the cancer.'
www.nature.com/articles/d41...
'COVID-19 mRNA vaccine acts like a siren and activates the immune system throughout the body - programming a response to kill the cancer.'
www.nature.com/articles/d41...
Reposted by Carl M
A wee little thing we have been working on over the past few month is now up and going - @thepointau.bsky.social.
Where to go for @amyremeikis.bsky.social's live blog, for analysis, fact checks, and details about things that might not be in "the news" but should be
thepoint.com.au
Where to go for @amyremeikis.bsky.social's live blog, for analysis, fact checks, and details about things that might not be in "the news" but should be
thepoint.com.au
The Point
The point.com.au
thepoint.com.au
October 23, 2025 at 5:25 AM
A wee little thing we have been working on over the past few month is now up and going - @thepointau.bsky.social.
Where to go for @amyremeikis.bsky.social's live blog, for analysis, fact checks, and details about things that might not be in "the news" but should be
thepoint.com.au
Where to go for @amyremeikis.bsky.social's live blog, for analysis, fact checks, and details about things that might not be in "the news" but should be
thepoint.com.au
Reposted by Carl M
A groundbreaking study reveals that cancer patients who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy lived dramatically longer than those who didn’t.
www.sciencedaily.com/releases/202...
www.sciencedaily.com/releases/202...
Cancer patients who got a COVID vaccine lived much longer
A groundbreaking study reveals that cancer patients who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy lived dramatically longer than those who didn’t. Researchers from the...
www.sciencedaily.com
October 20, 2025 at 2:43 AM
A groundbreaking study reveals that cancer patients who received a COVID-19 mRNA vaccine within 100 days of starting immunotherapy lived dramatically longer than those who didn’t.
www.sciencedaily.com/releases/202...
www.sciencedaily.com/releases/202...
Reposted by Carl M
“Progressive” leaders get trapped by the system.
Watch @graceblakeley.substack.com and @yanisvaroufakis.bsky.social on how only a united, global movement can take back real democracy.
Watch @graceblakeley.substack.com and @yanisvaroufakis.bsky.social on how only a united, global movement can take back real democracy.
Yanis Varoufakis & Grace Blakeley: Why Everything Feels Broken
YouTube video by DiEM25
youtu.be
October 20, 2025 at 9:30 AM
“Progressive” leaders get trapped by the system.
Watch @graceblakeley.substack.com and @yanisvaroufakis.bsky.social on how only a united, global movement can take back real democracy.
Watch @graceblakeley.substack.com and @yanisvaroufakis.bsky.social on how only a united, global movement can take back real democracy.
Reposted by Carl M
I has been a very long time since I posted this list of 40 consequences of climate change. But, it's important to take note of item number 40.
I truly wish things were going to get better, but sadly, it's all just going to get more f&%ked from here.
climatecasino.net/2021/10/top-...
I truly wish things were going to get better, but sadly, it's all just going to get more f&%ked from here.
climatecasino.net/2021/10/top-...
Top 40 Impacts of Climate Change
In this post, I list 78 current and future impacts of climate change, along with references for some of the more unexpected items. That list was compiled scouring the web along with suggestions and c...
climatecasino.net
October 10, 2025 at 12:21 AM
I has been a very long time since I posted this list of 40 consequences of climate change. But, it's important to take note of item number 40.
I truly wish things were going to get better, but sadly, it's all just going to get more f&%ked from here.
climatecasino.net/2021/10/top-...
I truly wish things were going to get better, but sadly, it's all just going to get more f&%ked from here.
climatecasino.net/2021/10/top-...
Reposted by Carl M
My favourite Jane Goodall quotes....so many, so to the point, so wise. How different the world would be if enough people listened to her.
October 2, 2025 at 2:36 AM
My favourite Jane Goodall quotes....so many, so to the point, so wise. How different the world would be if enough people listened to her.
Reposted by Carl M
Even with the recent downswing, daily global 2-meter surface temperatures are still running more than 1.5C above the 1850-1900 IPCC pre-industrial baseline.
Will this continue? The Climate 8-ball is putting on sunscreen.
Will this continue? The Climate 8-ball is putting on sunscreen.
September 28, 2025 at 2:37 PM
Even with the recent downswing, daily global 2-meter surface temperatures are still running more than 1.5C above the 1850-1900 IPCC pre-industrial baseline.
Will this continue? The Climate 8-ball is putting on sunscreen.
Will this continue? The Climate 8-ball is putting on sunscreen.
Reposted by Carl M
For those keeping track (and who isn't?), the planet is now at day 3 at 1.65C above the 1850-1900 pre-industrial baseline.
While MSM sells outrage 24/7 with Kimmel, Tylenol, Putin, Israel... collapse just doesn't make the cut. Do folks care about the end of everything anymore?
While MSM sells outrage 24/7 with Kimmel, Tylenol, Putin, Israel... collapse just doesn't make the cut. Do folks care about the end of everything anymore?
September 23, 2025 at 2:48 PM
For those keeping track (and who isn't?), the planet is now at day 3 at 1.65C above the 1850-1900 pre-industrial baseline.
While MSM sells outrage 24/7 with Kimmel, Tylenol, Putin, Israel... collapse just doesn't make the cut. Do folks care about the end of everything anymore?
While MSM sells outrage 24/7 with Kimmel, Tylenol, Putin, Israel... collapse just doesn't make the cut. Do folks care about the end of everything anymore?
Reposted by Carl M
It can be tricky to objectively diagnose anxiety and depression, but your nose could help doctors understand when you’re feeling the strain, says Gillian Forrester.
Why your nose could be the perfect window into your mental state
Diagnosing mental health conditions like anxiety and depression can be difficult, but it turns out that your nose could help doctors understand when you are feeling the strain, says Gillian Forrester
www.newscientist.com
September 20, 2025 at 8:55 AM
It can be tricky to objectively diagnose anxiety and depression, but your nose could help doctors understand when you’re feeling the strain, says Gillian Forrester.
Reposted by Carl M
Cool! Some gut microbes make 2-MiCit from propionate. In vitro, it inhibits 3D colon tumor growth (and normal cells at high dose). Just a 'lucky' one among millions of microbial by-products? I haven't thought of any selective advantage 🤔 Thoughts? 🦠🧪 #microsky #microbiomesky doi.org/10.1016/j.ce...
September 17, 2025 at 4:17 AM
Cool! Some gut microbes make 2-MiCit from propionate. In vitro, it inhibits 3D colon tumor growth (and normal cells at high dose). Just a 'lucky' one among millions of microbial by-products? I haven't thought of any selective advantage 🤔 Thoughts? 🦠🧪 #microsky #microbiomesky doi.org/10.1016/j.ce...
Reposted by Carl M
"Over the past 60 years, scientists have largely succeeded in building a computer model of Earth to see what the future holds. One of the most ambitious projects humankind has ever undertaken has now reached a critical moment." via @quantamagazine.bsky.social
How Climate Scientists Saw the Future Before It Arrived | Quanta Magazine
Over the past 60 years, scientists have largely succeeded in building a computer model of Earth to see what the future holds. One of the most ambitious projects humankind has ever undertaken has now r...
www.quantamagazine.org
September 16, 2025 at 12:47 PM
"Over the past 60 years, scientists have largely succeeded in building a computer model of Earth to see what the future holds. One of the most ambitious projects humankind has ever undertaken has now reached a critical moment." via @quantamagazine.bsky.social
Reposted by Carl M
Reposted by Carl M
The landscape of microbial associations in human cancer www.science.org/doi/10.1126/...
TLDR -- most cancers do not have microbiomes...but a few do have consistent microbe associations (i.e., colorectal and oral cancers). Make sense!
TLDR -- most cancers do not have microbiomes...but a few do have consistent microbe associations (i.e., colorectal and oral cancers). Make sense!
The landscape of microbial associations in human cancer
Differences between cancer types, infectious disease, and potential prognostic markers are uncovered by studying microbes within cancer DNA.
www.science.org
September 12, 2025 at 7:40 PM
The landscape of microbial associations in human cancer www.science.org/doi/10.1126/...
TLDR -- most cancers do not have microbiomes...but a few do have consistent microbe associations (i.e., colorectal and oral cancers). Make sense!
TLDR -- most cancers do not have microbiomes...but a few do have consistent microbe associations (i.e., colorectal and oral cancers). Make sense!
Reposted by Carl M
X-Mapper 🦠🧬🧪 - a sequence aligner developed for microbes, now on Bioconda! 🚀
• 11–24× fewer suboptimal alignments (same for human genome)
• 3–579× lower inconsistency
• improves on ~30% of reads aligned to non-target species
github.com/mathjeff/map...
bioconda.github.io/recipes/x-ma...
#microsky
• 11–24× fewer suboptimal alignments (same for human genome)
• 3–579× lower inconsistency
• improves on ~30% of reads aligned to non-target species
github.com/mathjeff/map...
bioconda.github.io/recipes/x-ma...
#microsky
September 15, 2025 at 2:32 AM
X-Mapper 🦠🧬🧪 - a sequence aligner developed for microbes, now on Bioconda! 🚀
• 11–24× fewer suboptimal alignments (same for human genome)
• 3–579× lower inconsistency
• improves on ~30% of reads aligned to non-target species
github.com/mathjeff/map...
bioconda.github.io/recipes/x-ma...
#microsky
• 11–24× fewer suboptimal alignments (same for human genome)
• 3–579× lower inconsistency
• improves on ~30% of reads aligned to non-target species
github.com/mathjeff/map...
bioconda.github.io/recipes/x-ma...
#microsky
Reposted by Carl M
Exercise and suppression of cancer
wapo.st/47EINFQ
wapo.st/47EINFQ
A single exercise session may slow cancer cell growth, new study shows
Exercise may not only help prevent cancer but also could fight it at a cellular level.
wapo.st
September 11, 2025 at 2:24 PM
Exercise and suppression of cancer
wapo.st/47EINFQ
wapo.st/47EINFQ
Reposted by Carl M
NEW PAPER! (in press in EPIDEMIOLOGY)
Have you wondered:
- How to specify a target trial: as an ideal trial or something else?
- What biases do target trial emulations and actual RCTs share?
- How does it all relate to potential outcomes?
Read here! 👉 arxiv.org/abs/2405.10026
#EpiSky #CausalSky
Have you wondered:
- How to specify a target trial: as an ideal trial or something else?
- What biases do target trial emulations and actual RCTs share?
- How does it all relate to potential outcomes?
Read here! 👉 arxiv.org/abs/2405.10026
#EpiSky #CausalSky
The ideal trial: defining causal estimands that balance relevance and feasibility in target trial emulations and actual randomized trials
Causal inference is the goal of randomized trials and many observational studies. The first step in a formal causal inference framework is to define the causal estimand, and in both types of study thi...
arxiv.org
September 9, 2025 at 11:23 PM
NEW PAPER! (in press in EPIDEMIOLOGY)
Have you wondered:
- How to specify a target trial: as an ideal trial or something else?
- What biases do target trial emulations and actual RCTs share?
- How does it all relate to potential outcomes?
Read here! 👉 arxiv.org/abs/2405.10026
#EpiSky #CausalSky
Have you wondered:
- How to specify a target trial: as an ideal trial or something else?
- What biases do target trial emulations and actual RCTs share?
- How does it all relate to potential outcomes?
Read here! 👉 arxiv.org/abs/2405.10026
#EpiSky #CausalSky
Reposted by Carl M
You don’t need perfect English or “great writer” skills. You need clarity, honesty, and persistence. Writing is a craft—you get better with practice
Read Claudia Ratti’s full essay in A Pocket Guide to Scientific Writing and Publishing 👉https://mybook.to/ScienceGuide
Read Claudia Ratti’s full essay in A Pocket Guide to Scientific Writing and Publishing 👉https://mybook.to/ScienceGuide
September 10, 2025 at 1:05 PM
You don’t need perfect English or “great writer” skills. You need clarity, honesty, and persistence. Writing is a craft—you get better with practice
Read Claudia Ratti’s full essay in A Pocket Guide to Scientific Writing and Publishing 👉https://mybook.to/ScienceGuide
Read Claudia Ratti’s full essay in A Pocket Guide to Scientific Writing and Publishing 👉https://mybook.to/ScienceGuide